chr22 : 26,068,692 – 26,069,369
677 bp 61 TFs 1 linked gene
This 677 bp open chromatin element is linked to SEZ6L and is bound by 61 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SEZ6L 100.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr22:26,063,692 – 26,074,369
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
61 transcription factors
Source
Cell type
AHR 1 dataset
ChIP MCF-7_DMSO_45min GSE90550.AHR.MCF-7_DMSO_45min 164 bp overlap
AR 1 dataset
ChIP MCF-7 ERP001226.AR.MCF-7 154 bp overlap
ARID1A 1 dataset
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 214 bp overlap
ARID1B 1 dataset
ChIP K-562 ENCSR822CCM.ARID1B.K-562 171 bp overlap
ARNTL 1 dataset
ChIP U2OS_trough_DMOG GSE85096.ARNTL.U2OS_trough_DMOG 78 bp overlap
BACH1 1 dataset
ChIP K-562 ENCSR740NPG.BACH1.K-562 244 bp overlap
BRD4 3 datasets
ChIP CHL-1_OTX015 GSE95585.BRD4.CHL-1_OTX015 614 bp overlap
ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 238 bp overlap
ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 210 bp overlap
CREB1 1 dataset
ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 98 bp overlap
CTCF 1 dataset
ChIP WI38 ENCFF841AXJ 317 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF031ISE 199 bp overlap
ChIP BLaER1 ENCFF460KDD 328 bp overlap
ELF1 1 dataset
ChIP K-562 ENCSR000BMD.ELF1.K-562 117 bp overlap
EMSY 1 dataset
ChIP K562 ENCFF511ZZZ 172 bp overlap
ESR1 33 datasets
ChIP MCF-7 GSE148277.ESR1.MCF-7 219 bp overlap
ChIP MCF-7 GSE76893.ESR1.MCF-7 170 bp overlap
ChIP MCF-7 GSE103023.ESR1.MCF-7 214 bp overlap
ChIP MCF-7 GSE48930.ESR1.MCF-7 211 bp overlap
ChIP MCF-7 GSE41561.ESR1.MCF-7 154 bp overlap
ChIP MCF-7_4OH-Tam GSE117941.ESR1.MCF-7_4OH-Tam 167 bp overlap
ChIP MCF-7_AZD2014 GSE103023.ESR1.MCF-7_AZD2014 206 bp overlap
ChIP MCF-7_D538G GSE148277.ESR1.MCF-7_D538G 275 bp overlap
ChIP MCF-7_D538G_DMSO GSE148277.ESR1.MCF-7_D538G_DMSO 266 bp overlap
ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 105 bp overlap
ChIP MCF-7_E2-10min-ERalpha GSE94023.ESR1.MCF-7_E2-10min-ERalpha 125 bp overlap
ChIP MCF-7_E2-1280-min-ERalpha GSE94023.ESR1.MCF-7_E2-1280-min-ERalpha 210 bp overlap
ChIP MCF-7_E2-160min-ERalpha GSE94023.ESR1.MCF-7_E2-160min-ERalpha 135 bp overlap
ChIP MCF-7_E2-20min-ERalpha GSE94023.ESR1.MCF-7_E2-20min-ERalpha 177 bp overlap
ChIP MCF-7_E2-320min-ERalpha GSE94023.ESR1.MCF-7_E2-320min-ERalpha 147 bp overlap
ChIP MCF-7_E2-40min-ERalpha GSE94023.ESR1.MCF-7_E2-40min-ERalpha 208 bp overlap
ChIP MCF-7_E2-5min-ERalpha GSE94023.ESR1.MCF-7_E2-5min-ERalpha 205 bp overlap
ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 229 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 181 bp overlap
ChIP MCF-7_HC11 GSE102882.ESR1.MCF-7_HC11 176 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 219 bp overlap
ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 260 bp overlap
ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 227 bp overlap
ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 192 bp overlap
ChIP MCF-7_SIGATA_E2 GSE40129.ESR1.MCF-7_SIGATA_E2 119 bp overlap
ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 128 bp overlap
ChIP MCF-7_Y537S_DMSO GSE148277.ESR1.MCF-7_Y537S_DMSO 167 bp overlap
ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 202 bp overlap
ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 284 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 237 bp overlap
ChIP MCF-7_jc5852 GSE126004.ESR1.MCF-7_jc5852 179 bp overlap
ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 234 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 156 bp overlap
ESR1_Y537N 2 datasets
ChIP MCF-7_E2_talen GSE94493.ESR1_Y537N.MCF-7_E2_talen 149 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 138 bp overlap
ESR1_Y537S 1 dataset
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 221 bp overlap
ESRRA 1 dataset
ChIP K562 ENCFF968PEP 374 bp overlap
EZH2 2 datasets
ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 603 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 183 bp overlap
FOS 2 datasets
ChIP MCF-7 ENCFF282FWZ 232 bp overlap
ChIP MCF-7 ENCSR569XNP.FOS.MCF-7 284 bp overlap
FOSL2 3 datasets
ChIP MCF-7 ENCFF716UWP 226 bp overlap
ChIP MCF-7 ENCSR546KCN.FOSL2.MCF-7 228 bp overlap
ChIP MCF-7 ENCSR000BUI.FOSL2.MCF-7 155 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 565 bp overlap
ChIP DE DE-FOXA2-2 580 bp overlap
GATA1 1 dataset
ChIP K-562 GSE107726.GATA1.K-562 222 bp overlap
GATA2 5 datasets
ChIP K-562 ENCSR000DKA.GATA2.K-562 417 bp overlap
ChIP K562 ENCFF830LLA 399 bp overlap
ChIP K562 ENCFF830LLA 577 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 134 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 379 bp overlap
GATA3 5 datasets
ChIP BE2C GSE65664.GATA3.BE2C 234 bp overlap
ChIP Kelly GSE65664.GATA3.Kelly 161 bp overlap
ChIP MCF-7 ENCFF352QVM 338 bp overlap
ChIP MCF-7 ENCFF437NQS 289 bp overlap
ChIP MCF-7 GSE51274.GATA3.MCF-7 295 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 677 bp overlap
ChIP DE DE-GATA4-2 677 bp overlap
ChIP foregut GSE117136.GATA4.foregut 473 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 628 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 502 bp overlap
GATA6 14 datasets
ChIP DE DE-GATA6-1 665 bp overlap
ChIP DE DE-GATA6-2 677 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 630 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 628 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 557 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 408 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 677 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 617 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 627 bp overlap
ChIP foregut GSE117136.GATA6.foregut 504 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 508 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 399 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 677 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 313 bp overlap
HAND2 1 dataset
ChIP Kelly GSE94822.HAND2.Kelly 234 bp overlap
HDAC2 1 dataset
ChIP MCF-7 ENCSR000BTP.HDAC2.MCF-7 173 bp overlap
HIF1A 2 datasets
ChIP U2OS_DMOG GSE85096.HIF1A.U2OS_DMOG 319 bp overlap
ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 247 bp overlap
JUN 5 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 273 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 249 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 265 bp overlap
ChIP MCF-7_E2 GSE102410.JUN.MCF-7_E2 147 bp overlap
ChIP MCF-7_Tamoxifen GSE102410.JUN.MCF-7_Tamoxifen 176 bp overlap
KDM5B 1 dataset
ChIP HCC2157 GSE46055.KDM5B.HCC2157 58 bp overlap
MAFG 2 datasets
ChIP K-562 ENCSR818DQV.MAFG.K-562 308 bp overlap
ChIP K562 ENCFF455EEO 203 bp overlap
MED26 1 dataset
ChIP HEK293T GSE121024.MED26.HEK293T 322 bp overlap
MEIS2 2 datasets
ChIP K-562 ENCSR851BNE.MEIS2.K-562 342 bp overlap
ChIP K562 ENCFF320GSD 247 bp overlap
MTA1 1 dataset
ChIP MCF-7 ENCSR348JOJ.MTA1.MCF-7 238 bp overlap
NANOG 4 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 240 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 364 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 196 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 245 bp overlap
NCOA2 1 dataset
ChIP MCF-7_E2 ERP000901.NCOA2.MCF-7_E2 156 bp overlap
NFE2 5 datasets
ChIP K-562 ENCSR552YGL.NFE2.K-562 269 bp overlap
ChIP K-562 ENCSR000FCC.NFE2.K-562 182 bp overlap
ChIP K562 ENCFF047YKA 214 bp overlap
ChIP K562 ENCFF163BSI 82 bp overlap
ChIP erythroid_R3R4 GSE43625.NFE2.erythroid_R3R4 85 bp overlap
NFE2L1 1 dataset
ChIP K-562 ENCSR632SHZ.NFE2L1.K-562 191 bp overlap
NFE2L2 4 datasets
ChIP BEAS-2B GSE145834.NFE2L2.BEAS-2B 210 bp overlap
ChIP BEAS-2B_arsenic GSE145834.NFE2L2.BEAS-2B_arsenic 175 bp overlap
ChIP Hep-G2 ENCSR488EES.NFE2L2.Hep-G2 124 bp overlap
ChIP K-562 ENCSR485GKE.NFE2L2.K-562 199 bp overlap
NIPBL 2 datasets
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 225 bp overlap
ChIP hESC_activin GSE64758.NIPBL.hESC_activin 227 bp overlap
NRIP1 2 datasets
ChIP MCF-7 ERP005838.NRIP1.MCF-7 133 bp overlap
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 195 bp overlap
PBX2 2 datasets
ChIP K-562 ENCSR263DFP.PBX2.K-562 336 bp overlap
ChIP K562 ENCFF286KMN 250 bp overlap
PDX1 2 datasets
ChIP hiPSC GSE125768.PDX1.hiPSC 220 bp overlap
ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 200 bp overlap
RARA 2 datasets
ChIP hiPSC_D5 GSE132532.RARA.hiPSC_D5 197 bp overlap
ChIP hiPSC_D5 GSE132532.RARA.hiPSC_D5 198 bp overlap
SIN3A 1 dataset
ChIP MCF-7 ENCSR000BUM.SIN3A.MCF-7 154 bp overlap
SMAD2-3 4 datasets
ChIP HGrC1_C134W GSE138496.SMAD2-3.HGrC1_C134W 126 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 615 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 677 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 574 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 533 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 407 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 596 bp overlap
SMARCA4 2 datasets
ChIP MCF-7 GSE123284.SMARCA4.MCF-7 207 bp overlap
ChIP MCF-7_parental GSE123284.SMARCA4.MCF-7_parental 164 bp overlap
SMARCB1 3 datasets
ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 209 bp overlap
ChIP MCF-7_DCDT GSE123284.SMARCB1.MCF-7_DCDT 183 bp overlap
ChIP MCF-7_estrogen GSE123284.SMARCB1.MCF-7_estrogen 283 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 243 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 439 bp overlap
SOX2 1 dataset
ChIP LK2_DNp63 GSE137459.SOX2.LK2_DNp63 270 bp overlap
STAT3 3 datasets
ChIP MCF-7_jc5836 GSE126004.STAT3.MCF-7_jc5836 172 bp overlap
ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 293 bp overlap
ChIP MCF-7_jc5840 GSE126004.STAT3.MCF-7_jc5840 190 bp overlap
TCF7L2 1 dataset
ChIP MDA-MB-453 GSE45201.TCF7L2.MDA-MB-453 83 bp overlap
TFAP2A 1 dataset
ChIP WA09 GSE105081.TFAP2A.WA09 111 bp overlap
TFAP2B 1 dataset
ChIP SK-N-SH ENCFF869XXQ 181 bp overlap
TFAP2C 4 datasets
ChIP HCC1954 GSE126897.TFAP2C.HCC1954 127 bp overlap
ChIP MCF-7_E2 GSE23852.TFAP2C.MCF-7_E2 87 bp overlap
ChIP MCF-7_ETOH GSE23852.TFAP2C.MCF-7_ETOH 131 bp overlap
ChIP WA09 GSE105081.TFAP2C.WA09 109 bp overlap
ZBTB7B 1 dataset
ChIP Hep-G2 ENCSR322ULL.ZBTB7B.Hep-G2 123 bp overlap
ZNF134 1 dataset
ChIP K-562 ENCSR553NTC.ZNF134.K-562 226 bp overlap
ZNF19 1 dataset
ChIP HEK293T GSE78099.ZNF19.HEK293T 133 bp overlap
ZNF316 1 dataset
ChIP K562 ENCFF838QCD 287 bp overlap
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