chr20:18,101,249–18,101,961

chr20 : 18,101,249 – 18,101,961

712 bp 74 TFs 6 linked genes

This 712 bp open chromatin element is linked to 6 target genes and is bound by 74 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
KAT14		36.2 kb	Distal	Multiome
PET117		36.2 kb	Distal	Multiome
OVOL2		42.5 kb	Distal	Multiome
MGME1		132.6 kb	Distal	Multiome
SNX5		132.8 kb	Distal	Multiome
ZNF133		186.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

74 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 478 bp overlap

ATF4 2 datasets

Motif DE_12h DE_12h-ATF4_MA0833.3 10 bp overlap

Motif DE_24h DE_24h-ATF4_MA0833.3 10 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 318 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 201 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

CCAR2 1 dataset

ChIP Hep-G2 ENCSR247XFV.CCAR2.Hep-G2 156 bp overlap

CEBPA 1 dataset

Motif DE_12h DE_12h-CEBPA_MA0102.5 10 bp overlap

CEBPD 1 dataset

Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap

CEBPG 2 datasets

Motif DE_12h DE_12h-CEBPG_MA1636.2 10 bp overlap

Motif DE_24h DE_24h-CEBPG_MA1636.2 10 bp overlap

ChIP T-47D_ETOH_45 GSE62428.CHD8.T-47D_ETOH_45 155 bp overlap

CTCF 2 datasets

ChIP GM12869 ENCSR000DRJ.CTCF.GM12869 103 bp overlap

ChIP GSC23 GSE139416.CTCF.GSC23 297 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 456 bp overlap

DMRTA1 2 datasets

Motif DE_12h DE_12h-DMRTA1_MA1707.2 10 bp overlap

Motif DE_24h DE_24h-DMRTA1_MA1707.2 10 bp overlap

DMRTC2 2 datasets

Motif DE_12h DE_12h-DMRTC2_MA1479.2 11 bp overlap

Motif DE_24h DE_24h-DMRTC2_MA1479.2 11 bp overlap

ERF::SREBF2 3 datasets

Motif DE_12h DE_12h-ERFSREBF2_MA1939.2 16 bp overlap

Motif DE_48h DE_48h-ERFSREBF2_MA1939.2 16 bp overlap

Motif DE_60h DE_60h-ERFSREBF2_MA1939.2 16 bp overlap

ESR1 2 datasets

ChIP MCF-7_E2 ERP000901.ESR1.MCF-7_E2 111 bp overlap

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 319 bp overlap

ESR1_Y537S 1 dataset

ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 204 bp overlap

ETV5::FIGLA 3 datasets

Motif DE_12h DE_12h-ETV5FIGLA_MA1945.2 14 bp overlap

Motif DE_48h DE_48h-ETV5FIGLA_MA1945.2 14 bp overlap

Motif DE_60h DE_60h-ETV5FIGLA_MA1945.2 14 bp overlap

EWSR1-FLI1 3 datasets

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap

Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap

ChIP T98G GSE112240.EZH2.T98G 484 bp overlap

FEZF2 2 datasets

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

FIGLA 3 datasets

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

FOXA1 4 datasets

ChIP LAPC-4_TFS_p358fs-V5 GSE123618.FOXA1.LAPC-4_TFS_p358fs-V5 219 bp overlap

ChIP T-47D_shRNF2 GSE137579.FOXA1.T-47D_shRNF2 198 bp overlap

ChIP T-47D_shRNF2_8h GSE137579.FOXA1.T-47D_shRNF2_8h 157 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 313 bp overlap

FOXA2 8 datasets

ChIP BJ1-hTERT_MimoRelease GSE92491.FOXA2.BJ1-hTERT_MimoRelease 263 bp overlap

ChIP DE DE-FOXA2-1 610 bp overlap

ChIP DE DE-FOXA2-2 665 bp overlap

ChIP HepG2 ENCFF570ABM 387 bp overlap

ChIP KerCT GSE90454.FOXA2.KerCT 237 bp overlap

ChIP PANC-1 GSE119930.FOXA2.PANC-1 269 bp overlap

ChIP PANC-1_EV GSE119930.FOXA2.PANC-1_EV 322 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 282 bp overlap

FOXH1 3 datasets

Motif DE_12h DE_12h-FOXH1_MA0479.2 8 bp overlap

Motif DE_48h DE_48h-FOXH1_MA0479.2 8 bp overlap

Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap

GABPA 1 dataset

ChIP VCaP GSE49091.GABPA.VCaP 134 bp overlap

GATA2 1 dataset

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 160 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-2 565 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 447 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 292 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 203 bp overlap

ChIP DE DE-GATA6-2 583 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 589 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 451 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 634 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 431 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 332 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 298 bp overlap

GRHL2 1 dataset

Motif DE_12h DE_12h-GRHL2_MA1105.3 8 bp overlap

HNRNPK 1 dataset

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 201 bp overlap

Hand1::Tcf3 3 datasets

Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap

Motif DE_48h DE_48h-Hand1Tcf3_MA0092.2 9 bp overlap

Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 383 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 329 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 409 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 712 bp overlap

KLF17 3 datasets

Motif DE_12h DE_12h-KLF17_MA1514.2 14 bp overlap

Motif DE_48h DE_48h-KLF17_MA1514.2 14 bp overlap

Motif DE_60h DE_60h-KLF17_MA1514.2 14 bp overlap

LCORL 1 dataset

ChIP Hep-G2 ENCSR950NAZ.LCORL.Hep-G2 200 bp overlap

Motif DE_12h DE_12h-MAFK_MA0496.4 10 bp overlap

ChIP MM1-S_JQ1_5000NM GSE49224.MED1.MM1-S_JQ1_5000NM 426 bp overlap

MXI1 3 datasets

Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap

Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap

Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap

NANOG 1 dataset

ChIP WA01 ENCSR000BMT.NANOG.WA01 69 bp overlap

NCOA3 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 215 bp overlap

NIPBL 1 dataset

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 378 bp overlap

NOTCH3 1 dataset

ChIP TALL-1_GSI GSE104261.NOTCH3.TALL-1_GSI 226 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 202 bp overlap

ChIP hiPSC GSE125768.PDX1.hiPSC 185 bp overlap

POU4F2 1 dataset

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 126 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 577 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 229 bp overlap

PRDM9 3 datasets

Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap

Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap

Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap

RAD21 1 dataset

ChIP hiPSC_CVI GSE106870.RAD21.hiPSC_CVI 86 bp overlap

RBM39 1 dataset

ChIP Hep-G2 ENCSR339JTP.RBM39.Hep-G2 186 bp overlap

Motif DE_12h DE_12h-RFX4_MA0799.3 13 bp overlap

Motif DE_12h DE_12h-RFX5_MA0510.3 14 bp overlap

Motif DE_12h DE_12h-RFX7_MA1554.2 8 bp overlap

Motif DE_12h DE_12h-Rfx6_MA1724.2 9 bp overlap

SIN3A 2 datasets

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 137 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 239 bp overlap

SMAD2 7 datasets

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap

Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap

ChIP endoderm GSE29422.SMAD2.endoderm 318 bp overlap

ChIP hESC GSE29422.SMAD2.hESC 255 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 712 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 534 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 431 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 643 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 712 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 668 bp overlap

SMAD2_3 7 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 538 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 625 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 712 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 630 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 566 bp overlap

ChIP ESC S23-ESC-d0-SMAD2_3-exp1 267 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 459 bp overlap

SMAD3 4 datasets

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 294 bp overlap

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 259 bp overlap

ChIP endoderm GSE29422.SMAD3.endoderm 227 bp overlap

ChIP hESC GSE29422.SMAD3.hESC 300 bp overlap

SMAD4 2 datasets

ChIP endoderm GSE29422.SMAD4.endoderm 345 bp overlap

ChIP hESC GSE29422.SMAD4.hESC 235 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 451 bp overlap

ChIP RENVM GSE49404.SOX2.RENVM 208 bp overlap

STAT3 7 datasets

ChIP T-47D_JC4735 GSE126004.STAT3.T-47D_JC4735 202 bp overlap

ChIP T-47D_JC4741 GSE126004.STAT3.T-47D_JC4741 301 bp overlap

ChIP T-47D_JC4751 GSE126004.STAT3.T-47D_JC4751 194 bp overlap

ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 426 bp overlap

ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 472 bp overlap

ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 425 bp overlap

ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 348 bp overlap

SUZ12 1 dataset

ChIP K-562 ENCSR000AUC.SUZ12.K-562 118 bp overlap

ChIP breast-organoid GSE113909.TP63.breast-organoid 147 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 296 bp overlap

Thap11 3 datasets

Motif DE_12h DE_12h-Thap11_MA1573.2 14 bp overlap

Motif DE_48h DE_48h-Thap11_MA1573.2 14 bp overlap

Motif DE_60h DE_60h-Thap11_MA1573.2 14 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 77 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 123 bp overlap

ZEB1 3 datasets

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

ChIP HEK293T ENCFF402JZW 691 bp overlap

ZNF354C 3 datasets

Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap

Motif DE_48h DE_48h-ZNF354C_MA0130.1 6 bp overlap

Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap

ZNF528 3 datasets

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

Motif DE_48h DE_48h-ZNF528_MA1597.1 17 bp overlap

Motif DE_60h DE_60h-ZNF528_MA1597.1 17 bp overlap

ZNF692 3 datasets

Motif DE_12h DE_12h-ZNF692_MA1986.2 8 bp overlap

Motif DE_48h DE_48h-ZNF692_MA1986.2 8 bp overlap

Motif DE_60h DE_60h-ZNF692_MA1986.2 8 bp overlap

ZNF770 1 dataset

Motif DE_12h DE_12h-ZNF770_MA2099.1 8 bp overlap