chr18 : 59,001,173 – 59,002,098
925 bp 76 TFs 2 linked genes
This 925 bp open chromatin element is linked to SEC11C and ZNF532 and is bound by 76 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SEC11C 138.4 kb Distal Multiome
ZNF532 138.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr18:58,996,173 – 59,007,098
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
76 transcription factors
Source
Cell type
AR 3 datasets
ChIP VCaP_DHAT_2H GSE28950.AR.VCaP_DHAT_2H 154 bp overlap
ChIP VCaP_R1881_30M GSE84432.AR.VCaP_R1881_30M 172 bp overlap
ChIP VCaP_R1881_4H GSE84432.AR.VCaP_R1881_4H 161 bp overlap
BRD3 1 dataset
ChIP H-1_DE GSE126661.BRD3.H-1_DE 279 bp overlap
BRD4 1 dataset
ChIP SUM159PT_100nMtrametinib_24h GSE87418.BRD4.SUM159PT_100nMtrametinib_24h 804 bp overlap
CEBPA 1 dataset
ChIP Kasumi-1_CEBPA-ER GSE102697.CEBPA.Kasumi-1_CEBPA-ER 141 bp overlap
CHD7 1 dataset
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 191 bp overlap
Crx 2 datasets
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
Dmbx1 2 datasets
Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_72h DE_72h-Dmbx1_MA0883.2 10 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 296 bp overlap
ESRRA 4 datasets
ChIP BT-474 GSE81651.ESRRA.BT-474 325 bp overlap
ChIP SK-BR-3 GSE81651.ESRRA.SK-BR-3 302 bp overlap
ChIP SK-BR-3_EGF GSE81651.ESRRA.SK-BR-3_EGF 248 bp overlap
ChIP SK-BR-3_HRG GSE81651.ESRRA.SK-BR-3_HRG 327 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 207 bp overlap
EWSR1-FLI1 3 datasets
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
FOXA1 1 dataset
ChIP LNCaP_R1881 GSE69043.FOXA1.LNCaP_R1881 174 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 745 bp overlap
ChIP DE DE-FOXA2-2 600 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 657 bp overlap
ChIP DE DE-GATA4-2 749 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
GATA5 4 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 12 datasets
ChIP DE DE-GATA6-1 735 bp overlap
ChIP DE DE-GATA6-2 844 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 531 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 428 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 667 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 530 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 307 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 700 bp overlap
GRHL2 1 dataset
ChIP T-47D GSE99680.GRHL2.T-47D 226 bp overlap
GSC 2 datasets
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 2 datasets
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Gata3 4 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HAND2 2 datasets
Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap
Motif DE_72h DE_72h-HAND2_MA1638.2 6 bp overlap
HIC2 2 datasets
Motif DE_48h DE_48h-HIC2_MA0738.2 6 bp overlap
Motif DE_72h DE_72h-HIC2_MA0738.2 6 bp overlap
HOXB13 2 datasets
ChIP prostate_2484 GSE130408.HOXB13.prostate_2484 189 bp overlap
ChIP prostate_P19 GSE130408.HOXB13.prostate_P19 97 bp overlap
HOXB4 2 datasets
Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap
Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap
HOXC4 2 datasets
Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap
Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap
HOXD4 2 datasets
Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap
Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap
KLF4 1 dataset
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 115 bp overlap
MEIS1 3 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 314 bp overlap
NKX6-3 2 datasets
Motif DE_48h DE_48h-NKX6-3_MA1530.2 8 bp overlap
Motif DE_72h DE_72h-NKX6-3_MA1530.2 8 bp overlap
Nr2e3 2 datasets
Motif DE_48h DE_48h-Nr2e3_MA0164.2 6 bp overlap
Motif DE_72h DE_72h-Nr2e3_MA0164.2 6 bp overlap
OTX1 2 datasets
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
OTX2 2 datasets
Motif DE_48h DE_48h-OTX2_MA0712.3 7 bp overlap
Motif DE_72h DE_72h-OTX2_MA0712.3 7 bp overlap
PITX1 2 datasets
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX2 2 datasets
Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap
Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap
PITX3 2 datasets
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
POU1F1 2 datasets
Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap
Motif DE_72h DE_72h-POU1F1_MA0784.3 14 bp overlap
POU2F1 2 datasets
Motif DE_48h DE_48h-POU2F1_MA0785.2 9 bp overlap
Motif DE_72h DE_72h-POU2F1_MA0785.2 9 bp overlap
POU2F1::SOX2 2 datasets
Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_72h DE_72h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F2 2 datasets
Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap
Motif DE_72h DE_72h-POU2F2_MA0507.3 13 bp overlap
POU2F3 2 datasets
Motif DE_48h DE_48h-POU2F3_MA0627.3 9 bp overlap
Motif DE_72h DE_72h-POU2F3_MA0627.3 9 bp overlap
POU3F1 2 datasets
Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap
Motif DE_72h DE_72h-POU3F1_MA0786.2 10 bp overlap
POU3F2 2 datasets
Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap
Motif DE_72h DE_72h-POU3F2_MA0787.1 12 bp overlap
POU3F3 2 datasets
Motif DE_48h DE_48h-POU3F3_MA0788.1 13 bp overlap
Motif DE_72h DE_72h-POU3F3_MA0788.1 13 bp overlap
POU3F4 2 datasets
Motif DE_48h DE_48h-POU3F4_MA0789.1 9 bp overlap
Motif DE_72h DE_72h-POU3F4_MA0789.1 9 bp overlap
POU4F2 2 datasets
Motif DE_48h DE_48h-POU4F2_MA0683.2 15 bp overlap
Motif DE_72h DE_72h-POU4F2_MA0683.2 15 bp overlap
POU5F1 1 dataset
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 762 bp overlap
POU5F1B 2 datasets
Motif DE_48h DE_48h-POU5F1B_MA0792.1 9 bp overlap
Motif DE_72h DE_72h-POU5F1B_MA0792.1 9 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 237 bp overlap
POU6F1 2 datasets
Motif DE_48h DE_48h-POU6F1_MA1549.2 7 bp overlap
Motif DE_72h DE_72h-POU6F1_MA1549.2 7 bp overlap
POU6F2 2 datasets
Motif DE_48h DE_48h-POU6F2_MA0793.2 9 bp overlap
Motif DE_72h DE_72h-POU6F2_MA0793.2 9 bp overlap
Pou5f1::Sox2 2 datasets
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_72h DE_72h-Pou5f1Sox2_MA0142.1 15 bp overlap
RELA 2 datasets
Motif DE_48h DE_48h-RELA_MA0107.1 10 bp overlap
Motif DE_72h DE_72h-RELA_MA0107.1 10 bp overlap
RHOXF1 2 datasets
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 169 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 799 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 478 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 280 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 510 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 428 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 555 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 538 bp overlap
SMARCA4 1 dataset
ChIP NSC GSE125033.SMARCA4.NSC 209 bp overlap
SOX15 3 datasets
Motif DE_36h DE_36h-SOX15_MA1152.2 7 bp overlap
Motif DE_48h DE_48h-SOX15_MA1152.2 7 bp overlap
Motif DE_72h DE_72h-SOX15_MA1152.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 519 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 791 bp overlap
SOX2 1 dataset
ChIP HNSC GSE69479.SOX2.HNSC 479 bp overlap
SP4 3 datasets
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap
Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap
SP5 3 datasets
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
SPIB 1 dataset
ChIP OCI-Ly3_SHCTR GSE56857.SPIB.OCI-Ly3_SHCTR 238 bp overlap
Sox6 3 datasets
Motif DE_36h DE_36h-Sox6_MA0515.1 10 bp overlap
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
THAP1 2 datasets
Motif DE_48h DE_48h-THAP1_MA0597.3 8 bp overlap
Motif DE_72h DE_72h-THAP1_MA0597.3 8 bp overlap
TRIM28 1 dataset
ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 297 bp overlap
TRPS1 4 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
VEZF1 2 datasets
Motif DE_48h DE_48h-VEZF1_MA1578.2 6 bp overlap
Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap
ZNF263 3 datasets
Motif DE_48h DE_48h-ZNF263_MA0528.3 7 bp overlap
Motif DE_60h DE_60h-ZNF263_MA0528.3 7 bp overlap
Motif DE_72h DE_72h-ZNF263_MA0528.3 7 bp overlap
ZNF281 2 datasets
Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
ZNF410 2 datasets
Motif DE_48h DE_48h-ZNF410_MA0752.2 16 bp overlap
Motif DE_72h DE_72h-ZNF410_MA0752.2 16 bp overlap
ZNF675 2 datasets
Motif DE_48h DE_48h-ZNF675_MA1714.2 19 bp overlap
Motif DE_72h DE_72h-ZNF675_MA1714.2 19 bp overlap
ZNF816 2 datasets
Motif DE_48h DE_48h-ZNF816_MA1719.2 15 bp overlap
Motif DE_72h DE_72h-ZNF816_MA1719.2 15 bp overlap
Zfp335 3 datasets
Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap
Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap
Motif DE_72h DE_72h-Zfp335_MA2002.2 7 bp overlap
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