chr1:213,066,260–213,067,034

chr1 : 213,066,260 – 213,067,034

774 bp 70 TFs 7 linked genes

This 774 bp open chromatin element is linked to 7 target genes and is bound by 70 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RPS6KC1		15.4 kb	Distal	Multiome
ANGEL2		51.2 kb	Distal	Multiome
VASH2		116.1 kb	Distal	Multiome
FLVCR1		208.4 kb	Distal	Multiome
FLVCR1-DT		208.5 kb	Distal	Multiome
TATDN3		274.7 kb	Distal	Multiome
NSL1		274.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

70 transcription factors

Arid3a 4 datasets

Motif DE_36h DE_36h-Arid3a_MA0151.1 6 bp overlap

Motif DE_48h DE_48h-Arid3a_MA0151.1 6 bp overlap

Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap

Motif DE_72h DE_72h-Arid3a_MA0151.1 6 bp overlap

Arid3b 1 dataset

Motif DE_60h DE_60h-Arid3b_MA0601.2 7 bp overlap

BARX2 1 dataset

Motif DE_60h DE_60h-BARX2_MA1471.2 9 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 355 bp overlap

CEBPA 6 datasets

ChIP Kasumi-1_CEBPA-ER GSE102697.CEBPA.Kasumi-1_CEBPA-ER 159 bp overlap

ChIP T-47D_progesterone GSE132649.CEBPA.T-47D_progesterone 275 bp overlap

ChIP T-47D_siCEBPA GSE132649.CEBPA.T-47D_siCEBPA 289 bp overlap

ChIP T-47D_siCtrl GSE132649.CEBPA.T-47D_siCtrl 269 bp overlap

ChIP THP-1_1-25D_24h GSE124032.CEBPA.THP-1_1-25D_24h 329 bp overlap

ChIP THP-1_1-25D_8h GSE124032.CEBPA.THP-1_1-25D_8h 133 bp overlap

CEBPB 18 datasets

ChIP A-549 ENCSR000BUB.CEBPB.A-549 157 bp overlap

ChIP A549 ENCFF235AIY 257 bp overlap

ChIP H1 ENCFF871PTR 261 bp overlap

ChIP HFOB_DIFF GSE82295.CEBPB.HFOB_DIFF 191 bp overlap

ChIP HeLa-S3 ENCFF722WEG 265 bp overlap

ChIP IMR-90 ENCFF468UGY 251 bp overlap

ChIP Ishikawa ENCFF010USJ 261 bp overlap

ChIP Ishikawa ENCSR000BTT.CEBPB.Ishikawa 227 bp overlap

ChIP Ishikawa ENCSR000BTT.CEBPB.Ishikawa 116 bp overlap

ChIP K-562 ENCSR000EHE.CEBPB.K-562 221 bp overlap

ChIP K-562 ENCSR000BRQ.CEBPB.K-562 188 bp overlap

ChIP K562 ENCFF189VBN 271 bp overlap

ChIP K562 ENCFF194QGF 321 bp overlap

ChIP K562 ENCFF584CTB 506 bp overlap

ChIP WA01 ENCSR000EBV.CEBPB.WA01 205 bp overlap

ChIP monocyte GSE98367.CEBPB.monocyte 194 bp overlap

ChIP monocyte_IFNg-LPS GSE120943.CEBPB.monocyte_IFNg-LPS 245 bp overlap

ChIP monocyte_INFg GSE98367.CEBPB.monocyte_INFg 250 bp overlap

CEBPG 4 datasets

ChIP K-562 ENCSR620VIC.CEBPG.K-562 364 bp overlap

ChIP K-562 ENCSR490LWA.CEBPG.K-562 343 bp overlap

ChIP K562 ENCFF783ADE 549 bp overlap

ChIP K562 ENCFF956TPS 511 bp overlap

Cebpa 6 datasets

ChIP BLaER1 ENCFF093OYK 340 bp overlap

ChIP BLaER1 ENCFF508JZF 441 bp overlap

ChIP BLaER1 ENCFF798NMV 353 bp overlap

ChIP BLaER1 ENCFF844FIP 256 bp overlap

ChIP BLaER1 ENCFF858JKM 457 bp overlap

ChIP BLaER1 ENCFF896HSY 388 bp overlap

Motif DE_36h DE_36h-Dux_MA0611.3 11 bp overlap

Motif DE_48h DE_48h-Dux_MA0611.3 11 bp overlap

Motif DE_60h DE_60h-Dux_MA0611.3 11 bp overlap

Motif DE_72h DE_72h-Dux_MA0611.3 11 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 402 bp overlap

EP300 2 datasets

ChIP Ishikawa ENCSR000BUE.EP300.Ishikawa 139 bp overlap

ChIP Ishikawa ENCSR000BUE.EP300.Ishikawa 61 bp overlap

ESR1 3 datasets

ChIP Ishikawa_C1-5 GSE147141.ESR1.Ishikawa_C1-5 235 bp overlap

ChIP Ishikawa_M1-9-1 GSE147141.ESR1.Ishikawa_M1-9-1 282 bp overlap

ChIP endometrioid-adenocarcinoma_tumor_3 GSE94031.ESR1.endometrioid-adenocarcinoma_tumor_3 312 bp overlap

ESRRA 1 dataset

Motif DE_60h DE_60h-ESRRA_MA0592.4 9 bp overlap

ESRRB 1 dataset

Motif DE_60h DE_60h-ESRRB_MA0141.4 10 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap

Elf5 4 datasets

Motif DE_36h DE_36h-Elf5_MA0136.4 8 bp overlap

Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap

Motif DE_60h DE_60h-Elf5_MA0136.4 8 bp overlap

Motif DE_72h DE_72h-Elf5_MA0136.4 8 bp overlap

FIGLA 4 datasets

Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 774 bp overlap

ChIP DE DE-FOXA2-2 762 bp overlap

FOXD2 1 dataset

Motif DE_72h DE_72h-FOXD2_MA0847.4 11 bp overlap

FOXE1 1 dataset

Motif DE_72h DE_72h-FOXE1_MA1487.3 12 bp overlap

Foxl2 1 dataset

Motif DE_72h DE_72h-Foxl2_MA1607.2 10 bp overlap

GATA2 1 dataset

ChIP TF1 GSE73207.GATA2.TF1 162 bp overlap

GATA4 3 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 175 bp overlap

ChIP DE DE-GATA4-1 689 bp overlap

ChIP DE DE-GATA4-2 774 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 652 bp overlap

ChIP DE DE-GATA6-2 774 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 314 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 639 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 362 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 610 bp overlap

Gfi1B 3 datasets

Motif DE_36h DE_36h-Gfi1B_MA0483.2 10 bp overlap

Motif DE_48h DE_48h-Gfi1B_MA0483.2 10 bp overlap

Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap

HAND2 1 dataset

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 229 bp overlap

ChIP HepG2 ENCFF854JLR 245 bp overlap

HNF1A 1 dataset

Motif DE_60h DE_60h-HNF1A_MA0046.3 13 bp overlap

HNF1B 1 dataset

Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap

IKZF2 4 datasets

Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap

Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap

Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap

Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap

Motif DE_60h DE_60h-IRF2_MA0051.2 16 bp overlap

Motif DE_60h DE_60h-Isl1_MA1608.2 7 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 250 bp overlap

MEF2A 2 datasets

Motif DE_60h DE_60h-MEF2A_MA0052.5 10 bp overlap

Motif DE_72h DE_72h-MEF2A_MA0052.5 10 bp overlap

MEF2B 2 datasets

Motif DE_60h DE_60h-MEF2B_MA0660.1 12 bp overlap

Motif DE_72h DE_72h-MEF2B_MA0660.1 12 bp overlap

MEF2C 2 datasets

Motif DE_60h DE_60h-MEF2C_MA0497.2 11 bp overlap

Motif DE_72h DE_72h-MEF2C_MA0497.2 11 bp overlap

MEF2D 2 datasets

Motif DE_60h DE_60h-MEF2D_MA0773.1 12 bp overlap

Motif DE_72h DE_72h-MEF2D_MA0773.1 12 bp overlap

MEIS1 3 datasets

Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

Motif DE_36h DE_36h-MSC_MA0665.1 10 bp overlap

Motif DE_48h DE_48h-MSC_MA0665.1 10 bp overlap

Motif DE_60h DE_60h-MSC_MA0665.1 10 bp overlap

Motif DE_72h DE_72h-MSC_MA0665.1 10 bp overlap

NANOG 2 datasets

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 207 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 199 bp overlap

NKX6-3 1 dataset

Motif DE_60h DE_60h-NKX6-3_MA1530.2 8 bp overlap

NR5A1 1 dataset

Motif DE_60h DE_60h-NR5A1_MA1540.3 12 bp overlap

NR6A1 1 dataset

Motif DE_60h DE_60h-NR6A1_MA1541.2 14 bp overlap

Nr2e1 1 dataset

Motif DE_60h DE_60h-Nr2e1_MA0676.1 9 bp overlap

Nr5A2 1 dataset

Motif DE_60h DE_60h-Nr5A2_MA0505.3 9 bp overlap

PBX3 3 datasets

Motif DE_36h DE_36h-PBX3_MA1114.2 11 bp overlap

Motif DE_48h DE_48h-PBX3_MA1114.2 11 bp overlap

Motif DE_60h DE_60h-PBX3_MA1114.2 11 bp overlap

PPARA::RXRA 1 dataset

Motif DE_60h DE_60h-PPARARXRA_MA1148.2 17 bp overlap

PRDM6 2 datasets

ChIP HEK293 ENCFF283AJL 445 bp overlap

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 529 bp overlap

Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 287 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 774 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 432 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 476 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 383 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 430 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 310 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 709 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 715 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 240 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 283 bp overlap

SMARCA4 2 datasets

ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 78 bp overlap

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 221 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 451 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 597 bp overlap

Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap

SREBF1 4 datasets

Motif DE_36h DE_36h-SREBF1_MA0829.3 10 bp overlap

Motif DE_48h DE_48h-SREBF1_MA0829.3 10 bp overlap

Motif DE_60h DE_60h-SREBF1_MA0829.3 10 bp overlap

Motif DE_72h DE_72h-SREBF1_MA0829.3 10 bp overlap

Sox6 4 datasets

Motif DE_36h DE_36h-Sox6_MA0515.1 10 bp overlap

Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap

Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 233 bp overlap

ChIP NPC GSE154479.TCF3.NPC 224 bp overlap

TCF7L2 1 dataset

Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap

TFAP4 8 datasets

Motif DE_36h DE_36h-TFAP4_MA0691.1 10 bp overlap

Motif DE_36h DE_36h-TFAP4_MA1570.1 10 bp overlap

Motif DE_48h DE_48h-TFAP4_MA0691.1 10 bp overlap

Motif DE_48h DE_48h-TFAP4_MA1570.1 10 bp overlap

Motif DE_60h DE_60h-TFAP4_MA0691.1 10 bp overlap

Motif DE_60h DE_60h-TFAP4_MA1570.1 10 bp overlap

Motif DE_72h DE_72h-TFAP4_MA0691.1 10 bp overlap

Motif DE_72h DE_72h-TFAP4_MA1570.1 10 bp overlap

VENTX 1 dataset

Motif DE_60h DE_60h-VENTX_MA0724.1 9 bp overlap

ZEB1 4 datasets

Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ZIM3 3 datasets

Motif DE_36h DE_36h-ZIM3_MA1709.2 11 bp overlap

Motif DE_48h DE_48h-ZIM3_MA1709.2 11 bp overlap

Motif DE_60h DE_60h-ZIM3_MA1709.2 11 bp overlap

ZNF75A 3 datasets

Motif DE_36h DE_36h-ZNF75A_MA2097.1 12 bp overlap

Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap

Motif DE_60h DE_60h-ZNF75A_MA2097.1 12 bp overlap

Zic1::Zic2 2 datasets

Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap

Zic3 2 datasets

Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap

Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap