chr12 : 74,546,835 – 74,548,107
1,272 bp 71 TFs 2 linked genes
This 1.3 kb open chromatin element is linked to ENSG00000257386 and ATXN7L3B and is bound by 71 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000257386 8.2 kb Proximal Proximity
ATXN7L3B 9.0 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:74,541,835 – 74,553,107
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
71 transcription factors
Source
Cell type
AR 1 dataset
ChIP LNCaP GSE80256.AR.LNCaP 196 bp overlap
ATF2 4 datasets
ChIP Hep-G2 ENCSR047BUZ.ATF2.Hep-G2 304 bp overlap
ChIP HepG2 ENCFF955VER 381 bp overlap
ChIP K-562 ENCSR869IUD.ATF2.K-562 302 bp overlap
ChIP K562 ENCFF139ZZG 391 bp overlap
ATF4 1 dataset
ChIP Jurkat_ZBTB1-KO_Asp-deprivation GSE145783.ATF4.Jurkat_ZBTB1-KO_Asp-deprivation 161 bp overlap
ATF7 3 datasets
ChIP Hep-G2 ENCSR545FXC.ATF7.Hep-G2 220 bp overlap
ChIP HepG2 ENCFF470FKK 381 bp overlap
ChIP MCF-7 ENCSR866QPZ.ATF7.MCF-7 224 bp overlap
BRD4 1 dataset
ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 313 bp overlap
CEBPA 1 dataset
ChIP Kasumi-1_CEBPA-ER_E2 GSE102697.CEBPA.Kasumi-1_CEBPA-ER_E2 260 bp overlap
CREB1 6 datasets
ChIP Hep-G2 ENCSR112ALD.CREB1.Hep-G2 242 bp overlap
ChIP HepG2 ENCFF792THT 391 bp overlap
ChIP MCF-7 ENCFF341ZEM 417 bp overlap
ChIP MCF-7 ENCFF867SAS 417 bp overlap
ChIP MCF-7 ENCSR897JAS.CREB1.MCF-7 293 bp overlap
ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 442 bp overlap
CTCF 1 dataset
ChIP THP-1_macrophage_PMA GSE96800.CTCF.THP-1_macrophage_PMA 223 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 383 bp overlap
ERF::FOXO1 1 dataset
Motif DE_36h DE_36h-ERFFOXO1_MA1936.2 12 bp overlap
ERF::HOXB13 1 dataset
Motif DE_36h DE_36h-ERFHOXB13_MA1937.2 13 bp overlap
ESR1 1 dataset
ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 223 bp overlap
ESR1_Y537N 2 datasets
ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 197 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 137 bp overlap
ESRRB 3 datasets
Motif DE_36h DE_36h-ESRRB_MA0141.4 10 bp overlap
Motif DE_48h DE_48h-ESRRB_MA0141.4 10 bp overlap
Motif DE_60h DE_60h-ESRRB_MA0141.4 10 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
Elf5 1 dataset
Motif DE_36h DE_36h-Elf5_MA0136.4 8 bp overlap
FEZF2 3 datasets
Motif DE_36h DE_36h-FEZF2_MA2341.1 8 bp overlap
Motif DE_48h DE_48h-FEZF2_MA2341.1 8 bp overlap
Motif DE_60h DE_60h-FEZF2_MA2341.1 8 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 571 bp overlap
ChIP DE DE-FOXA2-2 536 bp overlap
FOXC1 1 dataset
Motif DE_36h DE_36h-FOXC1_MA0032.2 11 bp overlap
FOXD3 1 dataset
Motif DE_36h DE_36h-FOXD3_MA0041.3 14 bp overlap
FOXH1 2 datasets
Motif DE_36h DE_36h-FOXH1_MA0479.2 8 bp overlap
Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap
FOXO1-PAX3 1 dataset
ChIP RH4_DMSO-6H GSE116344.FOXO1-PAX3.RH4_DMSO-6H 250 bp overlap
Foxl2 3 datasets
Motif DE_36h DE_36h-Foxl2_MA1607.2 10 bp overlap
Motif DE_48h DE_48h-Foxl2_MA1607.2 10 bp overlap
Motif DE_60h DE_60h-Foxl2_MA1607.2 10 bp overlap
Foxq1 2 datasets
Motif DE_36h DE_36h-Foxq1_MA0040.2 10 bp overlap
Motif DE_60h DE_60h-Foxq1_MA0040.2 10 bp overlap
GABPA 1 dataset
ChIP VCaP GSE49091.GABPA.VCaP 157 bp overlap
GATA2 4 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 222 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 624 bp overlap
ChIP DE DE-GATA4-2 633 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 273 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 225 bp overlap
GATA5 3 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 13 datasets
ChIP DE DE-GATA6-1 660 bp overlap
ChIP DE DE-GATA6-2 86 bp overlap
ChIP DE DE-GATA6-2 619 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 418 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 586 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 461 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 646 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 622 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 549 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 443 bp overlap
Gata3 3 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Gfi1B 3 datasets
Motif DE_36h DE_36h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_48h DE_48h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap
Hoxd13 3 datasets
Motif DE_36h DE_36h-Hoxd13_MA0909.4 7 bp overlap
Motif DE_48h DE_48h-Hoxd13_MA0909.4 7 bp overlap
Motif DE_60h DE_60h-Hoxd13_MA0909.4 7 bp overlap
IKZF2 1 dataset
Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap
KDM1A 1 dataset
ChIP K-562 ENCSR360HRA.KDM1A.K-562 302 bp overlap
MAX 1 dataset
ChIP WA01 ENCSR000EUP.MAX.WA01 138 bp overlap
MEIS1 4 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MXI1 3 datasets
Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap
MZF1 3 datasets
Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap
NR1H2::RXRA 3 datasets
Motif DE_36h DE_36h-NR1H2RXRA_MA0115.1 17 bp overlap
Motif DE_48h DE_48h-NR1H2RXRA_MA0115.1 17 bp overlap
Motif DE_60h DE_60h-NR1H2RXRA_MA0115.1 17 bp overlap
Nr2e1 3 datasets
Motif DE_36h DE_36h-Nr2e1_MA0676.1 9 bp overlap
Motif DE_48h DE_48h-Nr2e1_MA0676.1 9 bp overlap
Motif DE_60h DE_60h-Nr2e1_MA0676.1 9 bp overlap
PAX3-FOXO1 1 dataset
ChIP RH4 GSE140115.PAX3-FOXO1.RH4 264 bp overlap
PPARG 3 datasets
Motif DE_36h DE_36h-PPARG_MA0066.2 19 bp overlap
Motif DE_48h DE_48h-PPARG_MA0066.2 19 bp overlap
Motif DE_60h DE_60h-PPARG_MA0066.2 19 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 278 bp overlap
SMAD2-3 4 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 675 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 565 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 420 bp overlap
ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 1248 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 304 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 562 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 395 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 508 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 537 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 166 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 330 bp overlap
SOX10 3 datasets
Motif DE_36h DE_36h-SOX10_MA0442.3 6 bp overlap
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
SOX12 2 datasets
Motif DE_36h DE_36h-SOX12_MA1561.2 10 bp overlap
Motif DE_60h DE_60h-SOX12_MA1561.2 10 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 235 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 826 bp overlap
SOX8 1 dataset
ChIP RH4 GSE116344.SOX8.RH4 245 bp overlap
Six3 3 datasets
Motif DE_36h DE_36h-Six3_MA0631.2 11 bp overlap
Motif DE_48h DE_48h-Six3_MA0631.2 11 bp overlap
Motif DE_60h DE_60h-Six3_MA0631.2 11 bp overlap
Sox11 3 datasets
Motif DE_36h DE_36h-Sox11_MA0869.3 8 bp overlap
Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap
Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap
TBX19 4 datasets
Motif DE_36h DE_36h-TBX19_MA0804.2 17 bp overlap
Motif DE_48h DE_48h-TBX19_MA0804.2 17 bp overlap
Motif DE_60h DE_60h-TBX19_MA0804.2 17 bp overlap
Motif DE_72h DE_72h-TBX19_MA0804.2 17 bp overlap
TBXT 4 datasets
Motif DE_36h DE_36h-TBXT_MA0009.2 16 bp overlap
Motif DE_48h DE_48h-TBXT_MA0009.2 16 bp overlap
Motif DE_60h DE_60h-TBXT_MA0009.2 16 bp overlap
Motif DE_72h DE_72h-TBXT_MA0009.2 16 bp overlap
TCF7L1 3 datasets
Motif DE_36h DE_36h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_48h DE_48h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap
TCF7L2 3 datasets
Motif DE_36h DE_36h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
TEAD1 3 datasets
Motif DE_36h DE_36h-TEAD1_MA0090.4 9 bp overlap
Motif DE_48h DE_48h-TEAD1_MA0090.4 9 bp overlap
Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap
TEAD2 3 datasets
Motif DE_36h DE_36h-TEAD2_MA1121.2 7 bp overlap
Motif DE_48h DE_48h-TEAD2_MA1121.2 7 bp overlap
Motif DE_60h DE_60h-TEAD2_MA1121.2 7 bp overlap
TEAD3 3 datasets
Motif DE_36h DE_36h-TEAD3_MA0808.1 8 bp overlap
Motif DE_48h DE_48h-TEAD3_MA0808.1 8 bp overlap
Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap
TEAD4 3 datasets
Motif DE_36h DE_36h-TEAD4_MA0809.3 8 bp overlap
Motif DE_48h DE_48h-TEAD4_MA0809.3 8 bp overlap
Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap
TRPS1 3 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
USF1 3 datasets
Motif DE_36h DE_36h-USF1_MA0093.4 10 bp overlap
Motif DE_48h DE_48h-USF1_MA0093.4 10 bp overlap
Motif DE_60h DE_60h-USF1_MA0093.4 10 bp overlap
ZFP82 1 dataset
ChIP HEK293 GSE76494.ZFP82.HEK293 153 bp overlap
ZNF324 1 dataset
Motif DE_36h DE_36h-ZNF324_MA1977.2 14 bp overlap
ZNF354C 2 datasets
Motif DE_36h DE_36h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap
ZNF449 4 datasets
Motif DE_36h DE_36h-ZNF449_MA1656.2 10 bp overlap
Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap
Motif DE_60h DE_60h-ZNF449_MA1656.2 10 bp overlap
Motif DE_72h DE_72h-ZNF449_MA1656.2 10 bp overlap
ZNF582 3 datasets
Motif DE_36h DE_36h-ZNF582_MA1983.2 19 bp overlap
Motif DE_48h DE_48h-ZNF582_MA1983.2 19 bp overlap
Motif DE_60h DE_60h-ZNF582_MA1983.2 19 bp overlap
ZNF75A 1 dataset
Motif DE_36h DE_36h-ZNF75A_MA2097.1 12 bp overlap
ZSCAN16 3 datasets
Motif DE_36h DE_36h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_48h DE_48h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_60h DE_60h-ZSCAN16_MA2100.1 18 bp overlap
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