chr12 : 65,205,020 – 65,205,730
710 bp 69 TFs 1 linked gene
This 710 bp open chromatin element is linked to LEMD3 and is bound by 69 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
LEMD3 35.7 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:65,200,020 – 65,210,730
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
69 transcription factors
Source
Cell type
ARID1B 2 datasets
ChIP K-562 ENCSR822CCM.ARID1B.K-562 313 bp overlap
ChIP K562 ENCFF938UXQ 284 bp overlap
ATF2 1 dataset
ChIP GM12878 ENCFF066HPG 98 bp overlap
ATF4 3 datasets
Motif DE_36h DE_36h-ATF4_MA0833.3 10 bp overlap
Motif DE_48h DE_48h-ATF4_MA0833.3 10 bp overlap
Motif DE_72h DE_72h-ATF4_MA0833.3 10 bp overlap
CBFA2T2 2 datasets
ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 259 bp overlap
ChIP K562 ENCFF963TXY 174 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 375 bp overlap
ChIP K562 ENCFF673OEZ 319 bp overlap
CDX1 1 dataset
Motif DE_48h DE_48h-CDX1_MA0878.3 10 bp overlap
CDX4 1 dataset
Motif DE_48h DE_48h-CDX4_MA1473.2 9 bp overlap
CEBPG 3 datasets
Motif DE_36h DE_36h-CEBPG_MA1636.2 10 bp overlap
Motif DE_48h DE_48h-CEBPG_MA1636.2 10 bp overlap
Motif DE_72h DE_72h-CEBPG_MA1636.2 10 bp overlap
Crx 4 datasets
Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
DUX4 7 datasets
Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap
Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap
Motif DE_48h DE_48h-DUX4_MA0468.1 11 bp overlap
Motif DE_48h DE_48h-DUX4_MA0468.1 11 bp overlap
Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap
Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap
Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap
DUXA 3 datasets
Motif DE_36h DE_36h-DUXA_MA0884.2 13 bp overlap
Motif DE_48h DE_48h-DUXA_MA0884.2 13 bp overlap
Motif DE_72h DE_72h-DUXA_MA0884.2 13 bp overlap
Dmbx1 4 datasets
Motif DE_36h DE_36h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_72h DE_72h-Dmbx1_MA0883.2 10 bp overlap
Dux 3 datasets
Motif DE_36h DE_36h-Dux_MA0611.3 11 bp overlap
Motif DE_48h DE_48h-Dux_MA0611.3 11 bp overlap
Motif DE_72h DE_72h-Dux_MA0611.3 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 224 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 710 bp overlap
ChIP DE DE-FOXA2-2 562 bp overlap
GATA1 8 datasets
ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 74 bp overlap
ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 148 bp overlap
Motif DE_36h DE_36h-GATA1_MA0035.5 7 bp overlap
Motif DE_48h DE_48h-GATA1_MA0035.5 7 bp overlap
Motif DE_60h DE_60h-GATA1_MA0035.5 7 bp overlap
Motif DE_72h DE_72h-GATA1_MA0035.5 7 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 138 bp overlap
ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 459 bp overlap
GATA2 2 datasets
ChIP K562 ENCFF544PCK 251 bp overlap
ChIP TF1 GSE73207.GATA2.TF1 197 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 710 bp overlap
ChIP DE DE-GATA4-2 710 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 359 bp overlap
ChIP foregut GSE117136.GATA4.foregut 443 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 667 bp overlap
ChIP DE DE-GATA6-2 710 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 503 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 710 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 545 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 710 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 697 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 551 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 504 bp overlap
ChIP foregut GSE117136.GATA6.foregut 327 bp overlap
GSC 4 datasets
Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 4 datasets
Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
HOXA10 1 dataset
Motif DE_48h DE_48h-HOXA10_MA0899.2 9 bp overlap
HOXB13 1 dataset
Motif DE_48h DE_48h-HOXB13_MA0901.3 9 bp overlap
HOXD9 1 dataset
Motif DE_48h DE_48h-HOXD9_MA0913.3 9 bp overlap
Hmga1 1 dataset
Motif DE_48h DE_48h-Hmga1_MA2124.1 8 bp overlap
JUN 4 datasets
Motif DE_36h DE_36h-JUN_MA0488.2 10 bp overlap
Motif DE_48h DE_48h-JUN_MA0488.2 10 bp overlap
Motif DE_72h DE_72h-JUN_MA0488.2 10 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 299 bp overlap
JUNB 1 dataset
ChIP CD4 GSE116695.JUNB.CD4 376 bp overlap
KLF5 4 datasets
Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
Motif DE_60h DE_60h-KLF5_MA0599.1 10 bp overlap
Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap
LDB1 1 dataset
ChIP K-562 GSE142227.LDB1.K-562 224 bp overlap
MEF2A 1 dataset
Motif DE_48h DE_48h-MEF2A_MA0052.5 10 bp overlap
MEF2B 1 dataset
ChIP tonsil GSE110682.MEF2B.tonsil 97 bp overlap
MEF2C 1 dataset
Motif DE_48h DE_48h-MEF2C_MA0497.2 11 bp overlap
MLLT1 1 dataset
ChIP MOLM-13 GSE82116.MLLT1.MOLM-13 54 bp overlap
MXI1 4 datasets
Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap
Motif DE_72h DE_72h-MXI1_MA1108.3 6 bp overlap
MZF1 6 datasets
Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap
Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap
ChIP HEK293 ENCFF683ZWN 421 bp overlap
ChIP HEK293 ENCSR298QUH.MZF1.HEK293 341 bp overlap
NCOR1 3 datasets
ChIP K-562 ENCSR798ILC.NCOR1.K-562 215 bp overlap
ChIP K562 ENCFF788MPU 421 bp overlap
ChIP K562 ENCFF866HRM 441 bp overlap
NFATC2 2 datasets
ChIP CD4 GSE116695.NFATC2.CD4 318 bp overlap
ChIP CD4_CD28-ab GSE116695.NFATC2.CD4_CD28-ab 182 bp overlap
NFIC 1 dataset
ChIP K562 ENCFF167YID 442 bp overlap
NFYA 3 datasets
Motif DE_36h DE_36h-NFYA_MA0060.4 8 bp overlap
Motif DE_48h DE_48h-NFYA_MA0060.4 8 bp overlap
Motif DE_72h DE_72h-NFYA_MA0060.4 8 bp overlap
NFYC 3 datasets
Motif DE_36h DE_36h-NFYC_MA1644.2 7 bp overlap
Motif DE_48h DE_48h-NFYC_MA1644.2 7 bp overlap
Motif DE_72h DE_72h-NFYC_MA1644.2 7 bp overlap
OTX1 4 datasets
Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
OTX2 4 datasets
Motif DE_36h DE_36h-OTX2_MA0712.3 7 bp overlap
Motif DE_48h DE_48h-OTX2_MA0712.3 7 bp overlap
Motif DE_60h DE_60h-OTX2_MA0712.3 7 bp overlap
Motif DE_72h DE_72h-OTX2_MA0712.3 7 bp overlap
PITX1 4 datasets
Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX3 4 datasets
Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
PPARG 1 dataset
Motif DE_72h DE_72h-PPARG_MA0066.2 19 bp overlap
Pou5f1::Sox2 1 dataset
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
RARA 3 datasets
Motif DE_36h DE_36h-RARA_MA0729.1 18 bp overlap
Motif DE_48h DE_48h-RARA_MA0729.1 18 bp overlap
Motif DE_72h DE_72h-RARA_MA0729.1 18 bp overlap
RHOXF1 4 datasets
Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 678 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 652 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 270 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 340 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 535 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 619 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 701 bp overlap
SMARCA4 3 datasets
ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 149 bp overlap
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 227 bp overlap
ChIP K562 ENCFF506JCB 471 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 356 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 359 bp overlap
SP5 7 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
SPI1 3 datasets
ChIP primary-neutrophil_donorE GSE128834.SPI1.primary-neutrophil_donorE 99 bp overlap
ChIP primary-neutrophil_donorF GSE128834.SPI1.primary-neutrophil_donorF 145 bp overlap
ChIP primary-neutrophil_donorF GSE128834.SPI1.primary-neutrophil_donorF 106 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 262 bp overlap
TAL1 8 datasets
ChIP K-562 ENCSR106FRG.TAL1.K-562 333 bp overlap
ChIP K-562 ENCSR000EHB.TAL1.K-562 202 bp overlap
ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 158 bp overlap
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 144 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 212 bp overlap
ChIP K562 ENCFF620GMX 246 bp overlap
ChIP K562 ENCFF661CCK 277 bp overlap
ChIP ProEs GSE59087.TAL1.ProEs 154 bp overlap
TCF12 2 datasets
ChIP K-562 ENCSR744WOO.TCF12.K-562 349 bp overlap
ChIP K562 ENCFF931DJY 213 bp overlap
TCF3 1 dataset
ChIP K562 ENCFF319QZT 381 bp overlap
TEAD4 1 dataset
ChIP K562 ENCFF673NIK 365 bp overlap
THRA 4 datasets
Motif DE_36h DE_36h-THRA_MA1969.2 18 bp overlap
Motif DE_48h DE_48h-THRA_MA1969.2 18 bp overlap
Motif DE_60h DE_60h-THRA_MA1969.2 18 bp overlap
Motif DE_72h DE_72h-THRA_MA1969.2 18 bp overlap
TRIM24 3 datasets
ChIP K-562 ENCSR907MZR.TRIM24.K-562 204 bp overlap
ChIP K562 ENCFF284DKY 381 bp overlap
ChIP K562 ENCFF616RIL 437 bp overlap
VEZF1 4 datasets
Motif DE_36h DE_36h-VEZF1_MA1578.2 6 bp overlap
Motif DE_48h DE_48h-VEZF1_MA1578.2 6 bp overlap
Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap
Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap
Yy1 1 dataset
Motif DE_48h DE_48h-Yy1_MA0095.4 8 bp overlap
ZBTB7A 1 dataset
ChIP K-562 GSE103445.ZBTB7A.K-562 131 bp overlap
ZFP14 2 datasets
Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap
Motif DE_48h DE_48h-ZFP14_MA1972.1 15 bp overlap
ZKSCAN5 3 datasets
Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_72h DE_72h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF534 1 dataset
ChIP HEK293T GSE78099.ZNF534.HEK293T 141 bp overlap
ZNF816 3 datasets
Motif DE_36h DE_36h-ZNF816_MA1719.2 15 bp overlap
Motif DE_48h DE_48h-ZNF816_MA1719.2 15 bp overlap
Motif DE_72h DE_72h-ZNF816_MA1719.2 15 bp overlap
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