chr12:56,222,996–56,223,487

chr12 : 56,222,996 – 56,223,487

491 bp 38 TFs 26 linked genes

This 491 bp open chromatin element is linked to 26 target genes and is bound by 38 transcription factors.

Linked Genes

26 genes

Gene	Expression	Dist. to TSS	Distance	Link type
NABP2		982 bp	At TSS	Proximity
RNF41		1.1 kb	Proximal	Proximity
SMARCC2		33.6 kb	Distal	Multiome
ANKRD52		35.2 kb	Distal	Multiome+HiCAR
COQ10A		43.7 kb	Distal	Multiome+HiCAR
MYL6		64.8 kb	Distal	Multiome
MYL6B-AS1		64.9 kb	Distal	Multiome
MYL6B		70.7 kb	Distal	Multiome
CS		77.2 kb	Distal	Multiome
CNPY2		93.0 kb	Distal	Multiome
ESYT1		94.9 kb	Distal	Multiome
ZC3H10		104.9 kb	Distal	Multiome
RPL41		106.6 kb	Distal	Multiome
PAN2		110.8 kb	Distal	Multiome
PA2G4		118.6 kb	Distal	Multiome
STAT2		137.0 kb	Distal	Multiome
ERBB3		143.0 kb	Distal	Multiome
RPS26		181.3 kb	Distal	Multiome
IKZF4		215.5 kb	Distal	Multiome
SUOX		225.9 kb	Distal	Multiome
TIMELESS		226.2 kb	Distal	Multiome
SPRYD4		245.4 kb	Distal	Multiome
RAB5B		249.1 kb	Distal	Multiome
CDK2		256.4 kb	Distal	Multiome
PYM1		295.3 kb	Distal	Multiome
RBMS2		298.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

38 transcription factors

ChIP K562 ENCFF492SKF 84 bp overlap

ChIP MCF-7_aza GSE85352.ARNT.MCF-7_aza 246 bp overlap

ASCL1 1 dataset

ChIP SCLC_ASCLP_NE GSE61197.ASCL1.SCLC_ASCLP_NE 107 bp overlap

BCOR 2 datasets

ChIP K-562 ENCSR808AKZ.BCOR.K-562 304 bp overlap

ChIP K562 ENCFF343XWA 179 bp overlap

BRD2 4 datasets

ChIP K-562_DMSO GSE138084.BRD2.K-562_DMSO 298 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD2.K-562_DMSO-IFNG 315 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD2.K-562_iBET-BD2-IFNG 206 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD2.K-562_iBET-IFNG 238 bp overlap

BRD3 4 datasets

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 491 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 276 bp overlap

ChIP K-562_iBET-BD1-IFNG GSE138084.BRD3.K-562_iBET-BD1-IFNG 245 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD3.K-562_iBET-BD2-IFNG 298 bp overlap

BRD4 10 datasets

ChIP CLL_patient3 GSE109411.BRD4.CLL_patient3 247 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 224 bp overlap

ChIP HAP1 GSE108387.BRD4.HAP1 135 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD4.K-562_DMSO-IFNG 269 bp overlap

ChIP K-562_iBET-BD1-IFNG GSE138084.BRD4.K-562_iBET-BD1-IFNG 183 bp overlap

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 170 bp overlap

ChIP SW480 GSE110473.BRD4.SW480 149 bp overlap

ChIP SW480 GSE73319.BRD4.SW480 102 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 273 bp overlap

ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 281 bp overlap

CEBPA 1 dataset

ChIP Kasumi-1_CEBPA-ER_E2 GSE102697.CEBPA.Kasumi-1_CEBPA-ER_E2 100 bp overlap

CEBPB 1 dataset

ChIP HL-60_CEBPB_overexpressed GSE100486.CEBPB.HL-60_CEBPB_overexpressed 61 bp overlap

ChIP WTC11 ENCFF209ZUE 99 bp overlap

CTCF 2 datasets

ChIP T-47D_D538G GSE148277.CTCF.T-47D_D538G 107 bp overlap

ChIP colon_transverse ENCSR833FWC.CTCF.colon_transverse 129 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF031ISE 403 bp overlap

ChIP BLaER1 ENCFF093OYK 491 bp overlap

ChIP BLaER1 ENCFF364PUR 145 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

GABPB1 1 dataset

ChIP K-562 ENCSR138YYY.GABPB1.K-562 132 bp overlap

HDAC2 1 dataset

ChIP RH4_DMSO-6H_bioMerck GSE116344.HDAC2.RH4_DMSO-6H_bioMerck 159 bp overlap

ChIP K-562 ENCSR197ALX.HDGF.K-562 186 bp overlap

HNF4A 2 datasets

ChIP IM95 GSE114018.HNF4A.IM95 199 bp overlap

ChIP KATO-III GSE114018.HNF4A.KATO-III 149 bp overlap

INO80 1 dataset

ChIP Huh-7 GSE97411.INO80.Huh-7 83 bp overlap

ChIP PDAC GSE64557.KLF4.PDAC 446 bp overlap

MED1 2 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 155 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 255 bp overlap

MED26 1 dataset

ChIP HCT-116_aux GSE121355.MED26.HCT-116_aux 271 bp overlap

MLLT1 2 datasets

ChIP K-562 ENCSR107GRP.MLLT1.K-562 204 bp overlap

ChIP K562 ENCFF074XRJ 106 bp overlap

NELFCD 2 datasets

ChIP DLD-1_NELFCD-AID GSE144786.NELFCD.DLD-1_NELFCD-AID 128 bp overlap

ChIP DLD-1_NELFCD-AID GSE144786.NELFCD.DLD-1_NELFCD-AID 240 bp overlap

NELFE 1 dataset

ChIP DLD-1_NELFCD-AID GSE144786.NELFE.DLD-1_NELFCD-AID 224 bp overlap

PHIP 3 datasets

ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 106 bp overlap

ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 64 bp overlap

ChIP HCT-116_ab834 GSE101646.PHIP.HCT-116_ab834 61 bp overlap

POLR2A 2 datasets

ChIP endothelial cell of umbilical vein ENCFF467WJF 80 bp overlap

ChIP transverse colon ENCFF193UMS 491 bp overlap

POLR2G 1 dataset

ChIP K562 ENCFF047BLG 491 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 312 bp overlap

RBFOX2 2 datasets

ChIP K-562 GSE120104.RBFOX2.K-562 322 bp overlap

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 211 bp overlap

ChIP colorectal-cancer_shCDH1 GSE112555.REST.colorectal-cancer_shCDH1 71 bp overlap

SMARCA4 1 dataset

ChIP 22Rv1 GSE115615.SMARCA4.22Rv1 97 bp overlap

SUPT5H 2 datasets

ChIP DLD-1_NELFE-AID GSE144786.SUPT5H.DLD-1_NELFE-AID 246 bp overlap

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 255 bp overlap

TCF7L2 1 dataset

ChIP HCT-116 ENCSR000EUV.TCF7L2.HCT-116 188 bp overlap

ZBTB33 2 datasets

ChIP K562 ENCFF427SDV 420 bp overlap

ChIP K562 ENCFF875HLX 433 bp overlap

ZBTB38 1 dataset

ChIP HepG2 ENCFF875UQX 491 bp overlap

ZBTB40 1 dataset

ChIP K-562 ENCSR237VLT.ZBTB40.K-562 76 bp overlap

ZNF121 2 datasets

ChIP HEK293 ENCFF839FUF 430 bp overlap

ChIP WTC11 ENCFF291API 297 bp overlap

ZNF276 1 dataset

ChIP Hep-G2 ENCSR076KLJ.ZNF276.Hep-G2 240 bp overlap