chr12 : 41,466,840 – 41,467,263

423 bp 70 TFs 0 linked genes

This 423 bp open chromatin element has no linked target genes and is bound by 70 transcription factors.

Linked Genes

No linked genes

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

70 transcription factors

ATF6 1 dataset

Motif DE_60h DE_60h-ATF6_MA1466.2 13 bp overlap

Ahr::Arnt 2 datasets

Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap

Motif DE_60h DE_60h-AhrArnt_MA0006.2 5 bp overlap

BRD4 2 datasets

ChIP CHL-1_BAY123897 GSE95585.BRD4.CHL-1_BAY123897 313 bp overlap

ChIP hESC GSE33281.BRD4.hESC 68 bp overlap

Bach1::Mafk 1 dataset

Motif DE_60h DE_60h-Bach1Mafk_MA0591.2 12 bp overlap

CHD1 1 dataset

ChIP WA01 ENCSR000AQK.CHD1.WA01 153 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 267 bp overlap

CREB1 2 datasets

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 157 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 159 bp overlap

CTCF 1 dataset

ChIP hiPSC_IB12 GSE106870.CTCF.hiPSC_IB12 129 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 179 bp overlap

FERD3L 1 dataset

Motif DE_60h DE_60h-FERD3L_MA1485.1 14 bp overlap

GATA1 2 datasets

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 183 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 167 bp overlap

GATA2 1 dataset

ChIP TF1 GSE73207.GATA2.TF1 256 bp overlap

GATA4 16 datasets

ChIP DE DE-GATA4-1 369 bp overlap

ChIP DE DE-GATA4-2 418 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

ChIP ESO-26 GSE132813.GATA4.ESO-26 250 bp overlap

ChIP G296S GSE85628.GATA4.G296S 182 bp overlap

ChIP G296S_2 GSE85628.GATA4.G296S_2 182 bp overlap

ChIP G296S_4 GSE85628.GATA4.G296S_4 188 bp overlap

ChIP cardiomyocyte GSE85628.GATA4.cardiomyocyte 183 bp overlap

ChIP cardiomyocyte_1 GSE85628.GATA4.cardiomyocyte_1 199 bp overlap

ChIP cardiomyocyte_5 GSE85628.GATA4.cardiomyocyte_5 148 bp overlap

ChIP cardiomyocyte_7 GSE85628.GATA4.cardiomyocyte_7 224 bp overlap

ChIP foregut GSE117136.GATA4.foregut 389 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 383 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 421 bp overlap

GATA5 3 datasets

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

GATA6 15 datasets

ChIP DE DE-GATA6-1 372 bp overlap

ChIP DE DE-GATA6-2 421 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 307 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 395 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 287 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 396 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 393 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 319 bp overlap

ChIP PATU8988 GSE47535.GATA6.PATU8988 207 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 363 bp overlap

ChIP foregut GSE117136.GATA6.foregut 309 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 325 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 335 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 346 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 392 bp overlap

HNF1B 1 dataset

Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap

INO80 1 dataset

ChIP Huh-7 GSE97411.INO80.Huh-7 251 bp overlap

INSM1 1 dataset

Motif DE_60h DE_60h-INSM1_MA0155.1 12 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 349 bp overlap

KDM1A 2 datasets

ChIP NCI-H526_DMSO GSE66297.KDM1A.NCI-H526_DMSO 148 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 352 bp overlap

MAF::NFE2 1 dataset

Motif DE_60h DE_60h-MAFNFE2_MA0501.2 11 bp overlap

MAFG::NFE2L1 1 dataset

Motif DE_60h DE_60h-MAFGNFE2L1_MA0089.3 11 bp overlap

MEIS1 2 datasets

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

MEIS3 2 datasets

Motif DE_48h DE_48h-MEIS3_MA0775.2 7 bp overlap

Motif DE_60h DE_60h-MEIS3_MA0775.2 7 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 182 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 126 bp overlap

NFIA 1 dataset

Motif DE_60h DE_60h-NFIA_MA0670.2 6 bp overlap

NFIC 1 dataset

Motif DE_60h DE_60h-NFIC_MA0161.3 7 bp overlap

NFIX 1 dataset

Motif DE_60h DE_60h-NFIX_MA0671.2 6 bp overlap

NR2C1 1 dataset

Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap

NR3C1 1 dataset

ChIP A-549 ENCSR000BHF.NR3C1.A-549 129 bp overlap

Nfe2l2 1 dataset

Motif DE_60h DE_60h-Nfe2l2_MA0150.3 11 bp overlap

Nr1H2 1 dataset

Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap

PDX1 1 dataset

ChIP hiPSC GSE125768.PDX1.hiPSC 284 bp overlap

POU2F3 1 dataset

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 215 bp overlap

POU4F1 1 dataset

Motif DE_60h DE_60h-POU4F1_MA0790.2 12 bp overlap

POU4F2 1 dataset

Motif DE_60h DE_60h-POU4F2_MA0683.2 15 bp overlap

POU4F3 1 dataset

Motif DE_60h DE_60h-POU4F3_MA0791.2 12 bp overlap

POU5F1 1 dataset

ChIP BG03 GSE21614.POU5F1.BG03 155 bp overlap

RAD21 1 dataset

ChIP HAP1 GSE152721.RAD21.HAP1 189 bp overlap

RARA 1 dataset

Motif DE_60h DE_60h-RARA_MA0730.1 17 bp overlap

RARA::RXRA 1 dataset

Motif DE_60h DE_60h-RARARXRA_MA0159.1 17 bp overlap

RARA::RXRG 1 dataset

Motif DE_60h DE_60h-RARARXRG_MA1149.2 17 bp overlap

RBPJ 2 datasets

Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap

REST 1 dataset

ChIP neural ENCSR000BTV.REST.neural 141 bp overlap

RXR 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.RXR.pancreatic-progenitor_PP1 282 bp overlap

Rarb 1 dataset

Motif DE_60h DE_60h-Rarb_MA0858.1 17 bp overlap

SIN3A 2 datasets

ChIP WA01 ENCSR000EBO.SIN3A.WA01 163 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 146 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 264 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 348 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 242 bp overlap

SMARCA4 1 dataset

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 178 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 189 bp overlap

SMARCC1 1 dataset

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 291 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 199 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 292 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 317 bp overlap

SOX2 1 dataset

ChIP HNSC GSE69479.SOX2.HNSC 214 bp overlap

STAT3 1 dataset

ChIP MDA-MB-231 GSE152203.STAT3.MDA-MB-231 230 bp overlap

TAL1 4 datasets

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 229 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 195 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 235 bp overlap

ChIP PRIMA5 GSE33850.TAL1.PRIMA5 158 bp overlap

TEAD4 1 dataset

Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap

TP53 1 dataset

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 171 bp overlap

ZFP42 1 dataset

Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap

ZNF10 2 datasets

ChIP HEK293 ENCFF611ZJI 284 bp overlap

ChIP HEK293 ENCSR019WUS.ZNF10.HEK293 312 bp overlap

ZNF134 1 dataset

ChIP HEK293 GSE76494.ZNF134.HEK293 240 bp overlap

ZNF140 1 dataset

Motif DE_60h DE_60h-ZNF140_MA1589.2 19 bp overlap

ZNF22 1 dataset

ChIP HEK293 GSE76494.ZNF22.HEK293 72 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 171 bp overlap

ZNF93 1 dataset

Motif DE_60h DE_60h-ZNF93_MA1721.2 14 bp overlap