chr11:67,990,829–67,991,405

chr11 : 67,990,829 – 67,991,405

576 bp 54 TFs 6 linked genes

This 576 bp open chromatin element is linked to 6 target genes and is bound by 54 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
UNC93B1		13.0 kb	Distal	Multiome
NDUFS8		39.6 kb	Distal	Multiome
CHKA		130.3 kb	Distal	Multiome
KMT5B		222.6 kb	Distal	Multiome
C11orf24		280.9 kb	Distal	Multiome
ENSG00000286369		281.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

54 transcription factors

ARID4B 1 dataset

ChIP WTC11 ENCFF441HDK 431 bp overlap

Ahr::Arnt 3 datasets

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap

Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap

ChIP hESC GSE33281.BRD4.hESC 117 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 387 bp overlap

CREB1 3 datasets

ChIP H1 ENCFF955PMP 321 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 116 bp overlap

ChIP WTC11 ENCFF297VCI 371 bp overlap

E2F6 4 datasets

ChIP H1 ENCFF785DWK 451 bp overlap

ChIP K-562 ENCSR000BLI.E2F6.K-562 143 bp overlap

ChIP K562 ENCFF136LTS 325 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 142 bp overlap

EP400 1 dataset

ChIP K562 ENCFF850OZQ 576 bp overlap

EZH2 3 datasets

ChIP GM23248 ENCFF404ZHM 395 bp overlap

ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 247 bp overlap

ChIP neural progenitor cell ENCFF472NFV 457 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 374 bp overlap

Motif DE_24h DE_24h-HIC2_MA0738.2 6 bp overlap

HMGXB4 2 datasets

ChIP WTC11 ENCFF962POR 474 bp overlap

ChIP WTC11 ENCFF962POR 181 bp overlap

HNF4A 2 datasets

ChIP IM95 GSE114018.HNF4A.IM95 132 bp overlap

ChIP KATO-III GSE114018.HNF4A.KATO-III 236 bp overlap

KLF12 1 dataset

Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap

Motif DE_24h DE_24h-KLF3_MA1516.2 10 bp overlap

ChIP KATO-III GSE51705.KLF5.KATO-III 275 bp overlap

ChIP HEK293 ENCFF929IAJ 328 bp overlap

ChIP H1 ENCFF914VQY 319 bp overlap

ChIP HCT116 ENCFF810LEN 408 bp overlap

ChIP K562 ENCFF524IJO 226 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 186 bp overlap

ChIP WTC11 ENCFF223QFY 519 bp overlap

ChIP WTC11 ENCFF223QFY 439 bp overlap

MAX::MYC 2 datasets

Motif DE_12h DE_12h-MAXMYC_MA0059.2 10 bp overlap

Motif DE_24h DE_24h-MAXMYC_MA0059.2 10 bp overlap

MEIS1 1 dataset

Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap

ChIP K562 ENCFF820IGH 514 bp overlap

ChIP H1 ENCFF794ZJT 265 bp overlap

ChIP WA01 ENCSR000EBY.MYC.WA01 199 bp overlap

MYCN 3 datasets

ChIP Kelly GSE94782.MYCN.Kelly 131 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 196 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 277 bp overlap

NR2C1 2 datasets

Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap

Motif DE_24h DE_24h-NR2C1_MA1535.2 6 bp overlap

NR2C2 2 datasets

Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap

Motif DE_24h DE_24h-NR2C2_MA1536.2 6 bp overlap

NR3C1 1 dataset

ChIP A-549 ENCSR000BJR.NR3C1.A-549 106 bp overlap

Nr1H2 2 datasets

Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap

Motif DE_24h DE_24h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 2 datasets

Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap

Motif DE_24h DE_24h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 2 datasets

Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap

Motif DE_24h DE_24h-Nr1h3_MA2337.1 6 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 503 bp overlap

PHF8 2 datasets

ChIP H1 ENCFF427UFV 204 bp overlap

ChIP WA01 ENCSR000ATK.PHF8.WA01 206 bp overlap

POLR2A 9 datasets

ChIP GM18505 ENCFF311CYB 422 bp overlap

ChIP GM23338 ENCFF450WCS 325 bp overlap

ChIP H1 ENCFF566JSR 271 bp overlap

ChIP H1 ENCFF833NJP 215 bp overlap

ChIP HCT116 ENCFF508RDJ 183 bp overlap

ChIP spleen ENCFF044PYR 204 bp overlap

ChIP spleen ENCFF446ZGT 125 bp overlap

ChIP spleen ENCFF446ZGT 555 bp overlap

ChIP spleen ENCFF706IUS 576 bp overlap

POU5F1 2 datasets

ChIP BG03 GSE21614.POU5F1.BG03 234 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 402 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 248 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 239 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 333 bp overlap

RREB1 2 datasets

Motif DE_12h DE_12h-RREB1_MA0073.2 19 bp overlap

Motif DE_24h DE_24h-RREB1_MA0073.2 19 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 344 bp overlap

Rarg 2 datasets

Motif DE_12h DE_12h-Rarg_MA0860.1 17 bp overlap

Motif DE_24h DE_24h-Rarg_MA0860.1 17 bp overlap

SMAD3 1 dataset

ChIP WTC11 ENCFF815YYQ 357 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 130 bp overlap

ChIP WTC11 ENCFF688PEU 450 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 284 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 217 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 279 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 216 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 110 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 405 bp overlap

TGIF2 1 dataset

ChIP WTC11 ENCFF649SHI 411 bp overlap

THAP1 1 dataset

Motif DE_24h DE_24h-THAP1_MA0597.3 8 bp overlap

ChIP WTC11 ENCFF359JCU 513 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 143 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 255 bp overlap

ZBTB33 2 datasets

ChIP HepG2 ENCFF778UKV 337 bp overlap

ChIP K562 ENCFF875HLX 292 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_CSS GSE123089.ZBTB7A.VCaP_CSS 261 bp overlap

ZNF382 1 dataset

Motif DE_24h DE_24h-ZNF382_MA1594.1 24 bp overlap

ZSCAN16 1 dataset

Motif DE_24h DE_24h-ZSCAN16_MA2100.1 18 bp overlap

Motif DE_24h DE_24h-Zfx_MA0146.3 10 bp overlap