chr8 : 4,496,213 – 4,497,123

910 bp 78 TFs 1 linked gene

This 910 bp open chromatin element is linked to ENSG00000288110 and is bound by 78 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000288110		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

78 transcription factors

BRD4 1 dataset

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 439 bp overlap

CTCF 1 dataset

ChIP THP-1_macrophage_PMA GSE96800.CTCF.THP-1_macrophage_PMA 441 bp overlap

CTCFL 1 dataset

Motif DE_12h DE_12h-CTCFL_MA1102.3 8 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 187 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF262VBH 270 bp overlap

DUX4 1 dataset

Motif DE_12h DE_12h-DUX4_MA0468.1 11 bp overlap

EOMES 1 dataset

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

EP300 3 datasets

ChIP neural ENCSR843ZUP.EP300.neural 555 bp overlap

ChIP neural cell ENCFF442QNK 517 bp overlap

ChIP neural cell ENCFF442QNK 347 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

EZH2 3 datasets

ChIP A-1847 GSE95643.EZH2.A-1847 910 bp overlap

ChIP T-REx-293_K27WT_6h GSE118954.EZH2.T-REx-293_K27WT_6h 332 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 479 bp overlap

Foxl2 1 dataset

Motif DE_12h DE_12h-Foxl2_MA1607.2 10 bp overlap

GATA2 1 dataset

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 272 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 204 bp overlap

GATA6 3 datasets

ChIP DE DE-GATA6-1 206 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 168 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 289 bp overlap

Hnf1A 1 dataset

Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap

Lef1 1 dataset

Motif DE_12h DE_12h-Lef1_MA0768.3 8 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MGA 1 dataset

Motif DE_12h DE_12h-MGA_MA0801.1 8 bp overlap

MXI1 1 dataset

Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 430 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 261 bp overlap

ChIP hESC GSE18292.NANOG.hESC 93 bp overlap

NKX2-4 1 dataset

Motif DE_12h DE_12h-NKX2-4_MA2003.2 8 bp overlap

NR1H2::RXRA 1 dataset

Motif DE_12h DE_12h-NR1H2RXRA_MA0115.1 17 bp overlap

NR1H4::RXRA 1 dataset

Motif DE_12h DE_12h-NR1H4RXRA_MA1146.2 13 bp overlap

NR1I3 1 dataset

Motif DE_12h DE_12h-NR1I3_MA1534.2 8 bp overlap

NR2C1 1 dataset

Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap

Nr1H2 1 dataset

Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap

PDX1 1 dataset

ChIP hiPSC GSE125768.PDX1.hiPSC 185 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 385 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU5F1 1 dataset

ChIP HUES-8 GSE109524.POU5F1.HUES-8 549 bp overlap

Pparg::Rxra 1 dataset

Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap

REST 2 datasets

ChIP neural ENCSR000BTV.REST.neural 470 bp overlap

ChIP neural cell ENCFF882LXX 505 bp overlap

RXRA 1 dataset

ChIP WA01 ENCSR000BJW.RXRA.WA01 139 bp overlap

SIRT6 1 dataset

ChIP K-562 ENCSR000AUB.SIRT6.K-562 227 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 326 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 196 bp overlap

SMARCA4 6 datasets

ChIP NPC_K755R-pos GSE122631.SMARCA4.NPC_K755R-pos 196 bp overlap

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 500 bp overlap

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 176 bp overlap

ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 296 bp overlap

ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 384 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 726 bp overlap

SOX13 1 dataset

Motif DE_12h DE_12h-SOX13_MA1120.2 7 bp overlap

SOX14 1 dataset

Motif DE_12h DE_12h-SOX14_MA1562.2 9 bp overlap

SOX18 1 dataset

Motif DE_12h DE_12h-SOX18_MA1563.2 8 bp overlap

SOX2 4 datasets

Motif DE_12h DE_12h-SOX2_MA0143.5 7 bp overlap

ChIP HNSC GSE69479.SOX2.HNSC 584 bp overlap

ChIP hiPSC_INHI GSE67282.SOX2.hiPSC_INHI 271 bp overlap

ChIP hiPSC_KDP53_INHI GSE67282.SOX2.hiPSC_KDP53_INHI 234 bp overlap

SOX4 1 dataset

Motif DE_12h DE_12h-SOX4_MA0867.3 8 bp overlap

SOX8 3 datasets

Motif DE_12h DE_12h-SOX8_MA0868.3 7 bp overlap

ChIP RH4 GSE116344.SOX8.RH4 210 bp overlap

SOX9 1 dataset

Motif DE_12h DE_12h-SOX9_MA0077.2 8 bp overlap

SRY 1 dataset

Motif DE_12h DE_12h-SRY_MA0084.2 7 bp overlap

Sox11 1 dataset

Motif DE_12h DE_12h-Sox11_MA0869.3 8 bp overlap

Sox17 1 dataset

Motif DE_12h DE_12h-Sox17_MA0078.3 10 bp overlap

Sox3 1 dataset

Motif DE_12h DE_12h-Sox3_MA0514.3 7 bp overlap

Sox5 1 dataset

Motif DE_12h DE_12h-Sox5_MA0087.3 8 bp overlap

Sox6 1 dataset

Motif DE_12h DE_12h-Sox6_MA0515.1 10 bp overlap

Sox7 1 dataset

Motif DE_12h DE_12h-Sox7_MA2095.1 10 bp overlap

TAF1 1 dataset

ChIP WA01 ENCSR000BHO.TAF1.WA01 120 bp overlap

TBR1 1 dataset

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_12h DE_12h-TBX4_MA0806.1 8 bp overlap

TCF7 1 dataset

Motif DE_12h DE_12h-TCF7_MA0769.3 7 bp overlap

TCF7L1 1 dataset

Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 2 datasets

Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap

Tbx6 1 dataset

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF136 1 dataset

Motif DE_12h DE_12h-ZNF136_MA1588.1 15 bp overlap

ZNF257 1 dataset

Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap

ZNF281 1 dataset

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

ZNF354C 1 dataset

Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap

ZNF418 1 dataset

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap

ZNF675 1 dataset

Motif DE_12h DE_12h-ZNF675_MA1714.2 19 bp overlap

ZNF701 1 dataset

Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap

ZNF93 1 dataset

Motif DE_12h DE_12h-ZNF93_MA1721.2 14 bp overlap

Zfp809 1 dataset

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap

Znf423 1 dataset

Motif DE_12h DE_12h-Znf423_MA0116.1 15 bp overlap