chr7:149,870,542–149,871,523

chr7 : 149,870,542 – 149,871,523

981 bp 81 TFs 6 linked genes

This 981 bp open chromatin element is linked to 6 target genes and is bound by 81 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ATP6V0E2-AS1		2.3 kb	Proximal	Proximity
ATP6V0E2		2.4 kb	Proximal	Proximity
ZNF862		32.5 kb	Distal	Multiome
ZNF767P		246.2 kb	Distal	Multiome
RARRES2		470.8 kb	Distal	Multiome+HiCAR
ZNF775		508.4 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

81 transcription factors

ATF2 5 datasets

Motif DE_60h DE_60h-ATF2_MA1632.2 10 bp overlap

ChIP Hep-G2 ENCSR047BUZ.ATF2.Hep-G2 290 bp overlap

ChIP HepG2 ENCFF955VER 381 bp overlap

ChIP K-562 ENCSR869IUD.ATF2.K-562 205 bp overlap

ChIP K562 ENCFF139ZZG 391 bp overlap

Motif DE_60h DE_60h-ATF4_MA0833.3 10 bp overlap

Arid3a 1 dataset

Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap

BCL6 4 datasets

ChIP CD4 GSE59933.BCL6.CD4 207 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 622 bp overlap

ChIP OCI-Ly7 GSE44420.BCL6.OCI-Ly7 166 bp overlap

ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 163 bp overlap

ChIP SEM GSE83671.BRD4.SEM 320 bp overlap

CEBPG 1 dataset

Motif DE_60h DE_60h-CEBPG_MA1636.2 10 bp overlap

CREB1 1 dataset

Motif DE_60h DE_60h-CREB1_MA0018.5 8 bp overlap

CTCF 5 datasets

ChIP SEM GSE117864.CTCF.SEM 267 bp overlap

ChIP T-cell GSE115893.CTCF.T-cell 292 bp overlap

ChIP activated CD4-positive, alpha-beta T cell ENCFF095PZX 628 bp overlap

ChIP leukemia GSE142161.CTCF.leukemia 331 bp overlap

ChIP leukemia_CEBPA-24h GSE142161.CTCF.leukemia_CEBPA-24h 215 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF460KDD 120 bp overlap

Creb5 1 dataset

Motif DE_60h DE_60h-Creb5_MA0840.2 10 bp overlap

Motif DE_60h DE_60h-DBP_MA0639.2 10 bp overlap

DMRTA1 1 dataset

Motif DE_60h DE_60h-DMRTA1_MA1707.2 10 bp overlap

DMRTA2 1 dataset

Motif DE_60h DE_60h-DMRTA2_MA1478.2 6 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 352 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 313 bp overlap

ESR1 4 datasets

ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 274 bp overlap

ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 147 bp overlap

ChIP MCF-7_E2-5min-ERalpha GSE94023.ESR1.MCF-7_E2-5min-ERalpha 192 bp overlap

ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 181 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap

Motif DE_60h DE_60h-FOS_MA1951.2 13 bp overlap

FOS::JUN 1 dataset

Motif DE_60h DE_60h-FOSJUN_MA1126.2 10 bp overlap

FOSB::JUN 1 dataset

Motif DE_60h DE_60h-FOSBJUN_MA1127.1 11 bp overlap

FOSB::JUNB 1 dataset

Motif DE_60h DE_60h-FOSBJUNB_MA1136.1 10 bp overlap

FOSL1::JUN 1 dataset

Motif DE_60h DE_60h-FOSL1JUN_MA1129.1 10 bp overlap

FOSL1::JUND 1 dataset

Motif DE_60h DE_60h-FOSL1JUND_MA1143.2 9 bp overlap

FOSL2::JUN 1 dataset

Motif DE_60h DE_60h-FOSL2JUN_MA1131.2 10 bp overlap

FOSL2::JUNB 1 dataset

Motif DE_60h DE_60h-FOSL2JUNB_MA1139.2 10 bp overlap

FOSL2::JUND 1 dataset

Motif DE_60h DE_60h-FOSL2JUND_MA1145.2 10 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 450 bp overlap

ChIP DE DE-FOXA2-2 482 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 475 bp overlap

ChIP DE DE-GATA4-2 490 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 449 bp overlap

ChIP DE DE-GATA6-2 560 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 430 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 434 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 150 bp overlap

Motif DE_60h DE_60h-HLF_MA0043.4 9 bp overlap

HOXA4 1 dataset

Motif DE_60h DE_60h-HOXA4_MA1496.2 7 bp overlap

HOXB4 1 dataset

Motif DE_60h DE_60h-HOXB4_MA1499.2 6 bp overlap

HOXB9 1 dataset

Motif DE_60h DE_60h-HOXB9_MA1503.2 9 bp overlap

HOXC10 1 dataset

Motif DE_60h DE_60h-HOXC10_MA0905.2 9 bp overlap

HOXC4 1 dataset

Motif DE_60h DE_60h-HOXC4_MA1504.2 6 bp overlap

HOXC9 1 dataset

Motif DE_60h DE_60h-HOXC9_MA0485.3 9 bp overlap

HOXD11 1 dataset

Motif DE_60h DE_60h-HOXD11_MA0908.2 9 bp overlap

HOXD4 1 dataset

Motif DE_60h DE_60h-HOXD4_MA1507.2 6 bp overlap

Hoxa11 1 dataset

Motif DE_60h DE_60h-Hoxa11_MA0911.2 9 bp overlap

Motif DE_60h DE_60h-JDP2_MA0656.2 10 bp overlap

Motif DE_60h DE_60h-JUN_MA0488.2 10 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 340 bp overlap

JUN::JUNB 1 dataset

Motif DE_60h DE_60h-JUNJUNB_MA1133.2 11 bp overlap

Motif DE_60h DE_60h-JUNB_MA1140.3 11 bp overlap

Motif DE_60h DE_60h-JUND_MA0492.2 11 bp overlap

KDM1A 1 dataset

ChIP NCI-H526_DMSO GSE66297.KDM1A.NCI-H526_DMSO 73 bp overlap

KLF17 1 dataset

Motif DE_60h DE_60h-KLF17_MA1514.2 14 bp overlap

MEIS1 1 dataset

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

ChIP GM12878 ENCFF681QPL 306 bp overlap

ChIP Jurkat GSE59657.MYB.Jurkat 211 bp overlap

NFATC2 1 dataset

ChIP CD4 GSE116695.NFATC2.CD4 337 bp overlap

NKX6-1 1 dataset

Motif DE_60h DE_60h-NKX6-1_MA0674.2 7 bp overlap

NKX6-3 1 dataset

Motif DE_60h DE_60h-NKX6-3_MA1530.2 8 bp overlap

NR3C1 1 dataset

ChIP ALL_DEX GSE109946.NR3C1.ALL_DEX 200 bp overlap

NR4A1 1 dataset

Motif DE_60h DE_60h-NR4A1_MA1112.3 8 bp overlap

NR4A2 1 dataset

Motif DE_60h DE_60h-NR4A2_MA0160.3 8 bp overlap

NRIP1 1 dataset

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 169 bp overlap

PAX5 2 datasets

ChIP NALM-6 GSE126300.PAX5.NALM-6 538 bp overlap

ChIP NALM-6 GSE115764.PAX5.NALM-6 163 bp overlap

ChIP RCH-ACV GSE85988.PBX1.RCH-ACV 254 bp overlap

POU6F1 1 dataset

Motif DE_60h DE_60h-POU6F1_MA1549.2 7 bp overlap

POU6F2 1 dataset

Motif DE_60h DE_60h-POU6F2_MA0793.2 9 bp overlap

PPARA::RXRA 1 dataset

Motif DE_60h DE_60h-PPARARXRA_MA1148.2 17 bp overlap

PPARG 2 datasets

ChIP HT29_ROSIG_2H GSE77039.PPARG.HT29_ROSIG_2H 278 bp overlap

ChIP HT29_ROSIG_48H GSE77039.PPARG.HT29_ROSIG_48H 182 bp overlap

RUNX1 1 dataset

ChIP NALM-6 GSE126300.RUNX1.NALM-6 391 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 437 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 144 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 543 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 324 bp overlap

SMARCA4 3 datasets

ChIP J-Lat_GFP-Clone-A72_DMSO GSE100266.SMARCA4.J-Lat_GFP-Clone-A72_DMSO 309 bp overlap

ChIP J-Lat_GFP-Clone-A72_DMSO GSE100266.SMARCA4.J-Lat_GFP-Clone-A72_DMSO 418 bp overlap

ChIP J-Lat_GFP-Clone-A72_JQ1 GSE100266.SMARCA4.J-Lat_GFP-Clone-A72_JQ1 350 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 538 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 504 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 257 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

ChIP PRIMA5 GSE33850.TAL1.PRIMA5 154 bp overlap

TBX21 2 datasets

ChIP CD4_Th1 GSE62482.TBX21.CD4_Th1 155 bp overlap

ChIP Th1_CD3-CD28_donor2 GSE81881.TBX21.Th1_CD3-CD28_donor2 212 bp overlap

ChIP RCH-ACV GSE85988.TCF3.RCH-ACV 257 bp overlap

Motif DE_60h DE_60h-TEF_MA0843.2 10 bp overlap

TFDP1 1 dataset

ChIP K562 ENCFF584VSB 209 bp overlap

ZBTB33 5 datasets

ChIP GM12878 ENCSR542FLV.ZBTB33.GM12878 245 bp overlap

ChIP HepG2 ENCFF778UKV 337 bp overlap

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 380 bp overlap

ChIP K562 ENCFF427SDV 505 bp overlap

ChIP K562 ENCFF875HLX 465 bp overlap

ZFP36 6 datasets

ChIP A-549 ENCSR294JWV.ZFP36.A-549 85 bp overlap

ChIP GM12878 ENCSR900XDB.ZFP36.GM12878 270 bp overlap

ChIP K-562 ENCSR776CYN.ZFP36.K-562 128 bp overlap

ChIP K-562 ENCSR776CYN.ZFP36.K-562 142 bp overlap

ChIP K-562 ENCSR776CYN.ZFP36.K-562 180 bp overlap

ChIP K562 ENCFF255RZG 183 bp overlap

ZMYM3 1 dataset

ChIP K-562 ENCSR102KIN.ZMYM3.K-562 108 bp overlap

ZNF768 1 dataset

ChIP HepG2 ENCFF388QCK 440 bp overlap

ZNF784 1 dataset

Motif DE_60h DE_60h-ZNF784_MA1717.2 8 bp overlap