Predicted to enable protein dimerization activity and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZNF862. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF862 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF862, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr7:149,624,082–149,625,237 | 213.6 kb | Distal (>10kb) Multiome | 945 | |
| chr7:149,635,565–149,636,149 | 202.6 kb | Distal (>10kb) Multiome | 244 | |
| chr7:149,662,437–149,663,314 | 175.6 kb | Distal (>10kb) Multiome | 244 | |
| chr7:149,690,670–149,691,411 | 147.2 kb | Distal (>10kb) Multiome | 702 | |
| chr7:149,713,614–149,715,757 | 123.6 kb | Distal (>10kb) Multiome | 639 | |
| chr7:149,742,187–149,742,741 | 96.0 kb | Distal (>10kb) Multiome | 398 | |
| chr7:149,764,497–149,766,171 | 73.4 kb | Distal (>10kb) Multiome | 166 | |
| chr7:149,771,145–149,773,373 | 66.5 kb | Distal (>10kb) Multiome | 598 | |
| chr7:149,790,022–149,790,694 | 48.0 kb | Distal (>10kb) Multiome | 229 | |
| chr7:149,837,911–149,839,325 | 16 bp | At TSS Multiome | 871 | |
| chr7:149,870,542–149,871,523 | 32.5 kb | Distal (>10kb) Multiome | 81 | |
| chr7:149,872,817–149,874,446 | 35.5 kb | Distal (>10kb) Multiome | 826 | |
| chr7:150,988,543–150,989,168 | 1150.4 kb | Distal (>10kb) Multiome HiCAR | 348 |
Genomic view of the ZNF862 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.