chr7 : 125,264,093 – 125,264,967

874 bp 83 TFs 1 linked gene

This 874 bp open chromatin element is linked to ENSG00000219445 and is bound by 83 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000219445		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

83 transcription factors

AFF4 1 dataset

ChIP WTC11 ENCFF556XTF 445 bp overlap

Atoh1 1 dataset

Motif DE_12h DE_12h-Atoh1_MA1467.3 7 bp overlap

BRD3 1 dataset

ChIP K-562_IBET151_500nM GSE120715.BRD3.K-562_IBET151_500nM 83 bp overlap

Bach1::Mafk 1 dataset

Motif DE_12h DE_12h-Bach1Mafk_MA0591.2 12 bp overlap

CEBPD 1 dataset

Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap

CREB1 2 datasets

Motif DE_12h DE_12h-CREB1_MA0018.5 8 bp overlap

Motif ES_0h ES_0h-CREB1_MA0018.5 8 bp overlap

DUX4 1 dataset

Motif DE_12h DE_12h-DUX4_MA0468.1 11 bp overlap

E2F8 1 dataset

Motif DE_12h DE_12h-E2F8_MA0865.3 9 bp overlap

ERF::FIGLA 2 datasets

Motif DE_12h DE_12h-ERFFIGLA_MA1934.2 13 bp overlap

Motif DE_24h DE_24h-ERFFIGLA_MA1934.2 13 bp overlap

ESR2 1 dataset

Motif DE_12h DE_12h-ESR2_MA0258.2 15 bp overlap

ETV5::FIGLA 2 datasets

Motif DE_12h DE_12h-ETV5FIGLA_MA1945.2 14 bp overlap

Motif DE_24h DE_24h-ETV5FIGLA_MA1945.2 14 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

FIGLA 2 datasets

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap

FOS 1 dataset

Motif DE_12h DE_12h-FOS_MA1951.2 13 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-2 423 bp overlap

Foxq1 1 dataset

Motif DE_12h DE_12h-Foxq1_MA0040.2 10 bp overlap

GATA2 2 datasets

Motif DE_12h DE_12h-GATA2_MA0036.4 7 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 509 bp overlap

ChIP DE DE-GATA4-2 612 bp overlap

Motif DE_12h DE_12h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 456 bp overlap

GATA5 1 dataset

Motif DE_12h DE_12h-GATA5_MA0766.3 8 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 735 bp overlap

ChIP DE DE-GATA6-2 593 bp overlap

Motif DE_12h DE_12h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 703 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 570 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 814 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 243 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 495 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 496 bp overlap

ChIP foregut GSE117136.GATA6.foregut 433 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 256 bp overlap

Gata3 1 dataset

Motif DE_12h DE_12h-Gata3_MA0037.5 8 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

HIC2 1 dataset

Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap

Hmx2 1 dataset

Motif DE_12h DE_12h-Hmx2_MA0897.2 15 bp overlap

Hmx3 1 dataset

Motif DE_12h DE_12h-Hmx3_MA0898.2 9 bp overlap

ISL2 1 dataset

Motif DE_12h DE_12h-ISL2_MA0914.2 6 bp overlap

JUN 2 datasets

Motif DE_12h DE_12h-JUN_MA0488.2 10 bp overlap

Motif ES_0h ES_0h-JUN_MA0488.2 10 bp overlap

MAF 1 dataset

Motif DE_12h DE_12h-MAF_MA1520.2 13 bp overlap

MAFA 1 dataset

Motif DE_12h DE_12h-MAFA_MA1521.2 13 bp overlap

MAFF 2 datasets

Motif DE_12h DE_12h-MAFF_MA0495.4 11 bp overlap

Motif ES_0h ES_0h-MAFF_MA0495.4 11 bp overlap

MAFK 1 dataset

Motif DE_12h DE_12h-MAFK_MA0496.4 10 bp overlap

MAX 2 datasets

ChIP WTC11 ENCFF223QFY 585 bp overlap

ChIP WTC11 ENCFF223QFY 475 bp overlap

MEIS1 4 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MGA::EVX1 1 dataset

Motif ES_0h ES_0h-MGAEVX1_MA1960.2 11 bp overlap

MITF 2 datasets

Motif DE_12h DE_12h-MITF_MA0620.4 10 bp overlap

Motif DE_24h DE_24h-MITF_MA0620.4 10 bp overlap

Mafb 2 datasets

Motif DE_12h DE_12h-Mafb_MA0117.3 11 bp overlap

Motif ES_0h ES_0h-Mafb_MA0117.3 11 bp overlap

Mafg 1 dataset

Motif DE_12h DE_12h-Mafg_MA0659.4 12 bp overlap

Mecom 2 datasets

Motif DE_12h DE_12h-Mecom_MA0029.2 11 bp overlap

Motif DE_24h DE_24h-Mecom_MA0029.2 11 bp overlap

NANOG 5 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 293 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 490 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 453 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 269 bp overlap

NEUROD1 1 dataset

Motif DE_12h DE_12h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 1 dataset

Motif DE_12h DE_12h-NEUROG2_MA1642.2 7 bp overlap

NFKB1 2 datasets

Motif DE_12h DE_12h-NFKB1_MA0105.4 13 bp overlap

Motif DE_24h DE_24h-NFKB1_MA0105.4 13 bp overlap

NR2F1 1 dataset

Motif DE_12h DE_12h-NR2F1_MA0017.3 12 bp overlap

NR4A1 2 datasets

Motif DE_12h DE_12h-NR4A1_MA1112.3 8 bp overlap

Motif DE_24h DE_24h-NR4A1_MA1112.3 8 bp overlap

NRL 2 datasets

Motif DE_12h DE_12h-NRL_MA0842.3 12 bp overlap

Motif ES_0h ES_0h-NRL_MA0842.3 12 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA0668.3 8 bp overlap

Nkx3-2 1 dataset

Motif DE_12h DE_12h-Nkx3-2_MA0122.4 10 bp overlap

Nr1h3::Rxra 1 dataset

Motif DE_12h DE_12h-Nr1h3Rxra_MA0494.2 16 bp overlap

Nr2F6 1 dataset

Motif DE_12h DE_12h-Nr2F6_MA0728.1 15 bp overlap

Nr2e1 2 datasets

Motif DE_12h DE_12h-Nr2e1_MA0676.1 9 bp overlap

Motif DE_24h DE_24h-Nr2e1_MA0676.1 9 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 396 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 432 bp overlap

RXRA::VDR 1 dataset

Motif DE_12h DE_12h-RXRAVDR_MA0074.1 15 bp overlap

Rarb 1 dataset

Motif DE_12h DE_12h-Rarb_MA0857.1 16 bp overlap

Rarg 1 dataset

Motif DE_12h DE_12h-Rarg_MA0859.2 15 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 302 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 272 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

SREBF1 4 datasets

Motif DE_12h DE_12h-SREBF1_MA0595.1 10 bp overlap

Motif DE_12h DE_12h-SREBF1_MA0829.3 10 bp overlap

Motif DE_24h DE_24h-SREBF1_MA0595.1 10 bp overlap

Motif DE_24h DE_24h-SREBF1_MA0829.3 10 bp overlap

SREBF2 2 datasets

Motif DE_12h DE_12h-SREBF2_MA0828.3 10 bp overlap

Motif DE_24h DE_24h-SREBF2_MA0828.3 10 bp overlap

Stat6 1 dataset

Motif DE_12h DE_12h-Stat6_MA0520.2 10 bp overlap

TBX19 1 dataset

Motif DE_12h DE_12h-TBX19_MA0804.2 17 bp overlap

TEAD1 3 datasets

Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap

ChIP WTC11 ENCFF502QUV 405 bp overlap

TEAD2 1 dataset

Motif ES_0h ES_0h-TEAD2_MA1121.2 7 bp overlap

TEAD3 1 dataset

Motif ES_0h ES_0h-TEAD3_MA0808.1 8 bp overlap

TEAD4 1 dataset

Motif ES_0h ES_0h-TEAD4_MA0809.3 8 bp overlap

THAP1 1 dataset

Motif ES_0h ES_0h-THAP1_MA0597.3 8 bp overlap

TRPS1 1 dataset

Motif DE_12h DE_12h-TRPS1_MA1970.2 8 bp overlap

TWIST1 1 dataset

Motif DE_12h DE_12h-TWIST1_MA1123.3 8 bp overlap

USF1 3 datasets

Motif DE_12h DE_12h-USF1_MA0093.4 10 bp overlap

Motif DE_24h DE_24h-USF1_MA0093.4 10 bp overlap

ChIP WTC11 ENCFF699QGS 425 bp overlap

USF2 3 datasets

Motif DE_12h DE_12h-USF2_MA0526.5 10 bp overlap

Motif DE_24h DE_24h-USF2_MA0526.5 10 bp overlap

ChIP WTC11 ENCFF139JAW 417 bp overlap

ZEB1 2 datasets

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap

ZIC1 1 dataset

Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap

ZIC4 1 dataset

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

ZIC5 1 dataset

Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap

ZKSCAN1 2 datasets

Motif DE_12h DE_12h-ZKSCAN1_MA1585.2 9 bp overlap

Motif DE_24h DE_24h-ZKSCAN1_MA1585.2 9 bp overlap

ZNF16 1 dataset

Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap

ZNF416 1 dataset

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

ZNF454 2 datasets

Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap

Motif DE_24h DE_24h-ZNF454_MA1712.2 17 bp overlap

ZNF528 1 dataset

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

ZNF582 1 dataset

Motif DE_12h DE_12h-ZNF582_MA1983.2 19 bp overlap

ZNF677 2 datasets

Motif DE_12h DE_12h-ZNF677_MA2101.1 12 bp overlap

Motif DE_24h DE_24h-ZNF677_MA2101.1 12 bp overlap

ZNF684 1 dataset

Motif ES_0h ES_0h-ZNF684_MA1600.2 14 bp overlap

ZNF707 1 dataset

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap

ZNF85 2 datasets

Motif DE_12h DE_12h-ZNF85_MA1720.2 12 bp overlap

Motif DE_24h DE_24h-ZNF85_MA1720.2 12 bp overlap