chr7:65,233,376–65,233,924

chr7 : 65,233,376 – 65,233,924

548 bp 61 TFs 6 linked genes

This 548 bp open chromatin element is linked to 6 target genes and is bound by 61 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000289108		18.7 kb	Distal	Multiome
ENSG00000282381		35.7 kb	Distal	Multiome
ZNF92		140.1 kb	Distal	Multiome
CCT6P3		195.4 kb	Distal	Multiome
ERV3-1		227.0 kb	Distal	Multiome
ZNF117		227.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

61 transcription factors

ChIP LNCaP GSE80256.AR.LNCaP 191 bp overlap

ARID1A 1 dataset

ChIP 12Z GSE129781.ARID1A.12Z 359 bp overlap

Ascl2 1 dataset

Motif DE_72h DE_72h-Ascl2_MA0816.1 10 bp overlap

BHLHE22 1 dataset

Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap

ChIP Jurkat GSE83777.BRD4.Jurkat 256 bp overlap

CBFA2T3 1 dataset

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 224 bp overlap

ChIP SET-2 GSE65138.CDK8.SET-2 189 bp overlap

CDK9 2 datasets

ChIP MOLT-4_DMSO GSE79288.CDK9.MOLT-4_DMSO 203 bp overlap

ChIP MOLT-4_JQ1 GSE79288.CDK9.MOLT-4_JQ1 166 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 281 bp overlap

ChIP Jurkat GSE49091.ERG.Jurkat 252 bp overlap

ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 165 bp overlap

ESR1 4 datasets

ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 325 bp overlap

ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 345 bp overlap

ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 348 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 228 bp overlap

ChIP MDA-MB-231_estradiol GSE108979.ESR2.MDA-MB-231_estradiol 265 bp overlap

ETS1 3 datasets

ChIP 786-O GSE86092.ETS1.786-O 221 bp overlap

ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 67 bp overlap

ChIP THP-6_shCtrl GSE138516.ETS1.THP-6_shCtrl 346 bp overlap

ChIP COLO-800 GSE80443.ETV1.COLO-800 237 bp overlap

FOXL2 1 dataset

ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 168 bp overlap

FOXO1 1 dataset

ChIP CD34 GSE80773.FOXO1.CD34 168 bp overlap

GATA1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 173 bp overlap

GATA2 5 datasets

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 229 bp overlap

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 365 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 292 bp overlap

ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 133 bp overlap

GATA3 2 datasets

ChIP Jurkat GSE76181.GATA3.Jurkat 411 bp overlap

ChIP Jurkat GSE68976.GATA3.Jurkat 250 bp overlap

GATA4 7 datasets

ChIP DE DE-GATA4-1 525 bp overlap

ChIP DE DE-GATA4-2 548 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 280 bp overlap

ChIP foregut GSE117136.GATA4.foregut 455 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 362 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 375 bp overlap

GATA5 1 dataset

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 16 datasets

ChIP AGS GSE51705.GATA6.AGS 319 bp overlap

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 102 bp overlap

ChIP DE DE-GATA6-1 504 bp overlap

ChIP DE DE-GATA6-2 548 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 524 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 548 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 452 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 548 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 548 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 484 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 473 bp overlap

ChIP foregut GSE117136.GATA6.foregut 461 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 314 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 310 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 377 bp overlap

GRHL2 1 dataset

ChIP HBE GSE46194.GRHL2.HBE 169 bp overlap

Gata3 1 dataset

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

IKZF1 1 dataset

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 425 bp overlap

IKZF3 1 dataset

ChIP pre-B-cell GSE107886.IKZF3.pre-B-cell 260 bp overlap

JMJD1C 1 dataset

ChIP NB4 GSE63484.JMJD1C.NB4 152 bp overlap

ChIP 786-O GSE86092.JUN.786-O 279 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 283 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 548 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 286 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 263 bp overlap

ChIP Karpas-299 GSE151413.JUN.Karpas-299 548 bp overlap

ChIP Jurkat GSE94391.LMO1.Jurkat 266 bp overlap

ChIP TSU-1621MT GSE60477.LMO2.TSU-1621MT 147 bp overlap

ChIP pre-B-cell GSE107886.MTA2.pre-B-cell 204 bp overlap

ChIP DU528 GSE94000.MYB.DU528 293 bp overlap

ChIP Jurkat GSE59657.MYB.Jurkat 347 bp overlap

ChIP Loucy GSE94000.MYB.Loucy 244 bp overlap

ChIP MOLT-3 GSE59657.MYB.MOLT-3 152 bp overlap

ChIP PF-382 GSE94000.MYB.PF-382 397 bp overlap

Motif DE_72h DE_72h-MYOG_MA0500.3 8 bp overlap

NHLH1 1 dataset

Motif DE_72h DE_72h-NHLH1_MA0048.3 9 bp overlap

NHLH2 1 dataset

Motif DE_72h DE_72h-NHLH2_MA1529.2 16 bp overlap

NOTCH1 1 dataset

ChIP CUTLL1 GSE29600.NOTCH1.CUTLL1 89 bp overlap

NR3C1 2 datasets

ChIP BEAS-2B_TNF_IA1 GSE125623.NR3C1.BEAS-2B_TNF_IA1 309 bp overlap

ChIP BEAS-2B_Veh_IA1 GSE125623.NR3C1.BEAS-2B_Veh_IA1 361 bp overlap

Neurod2 1 dataset

Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap

Olig2 1 dataset

Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap

Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap

ChIP ME-1_KD GSE128771.RNF2.ME-1_KD 232 bp overlap

RUNX1 6 datasets

ChIP 697 GSE138031.RUNX1.697 196 bp overlap

ChIP Jurkat GSE76181.RUNX1.Jurkat 199 bp overlap

ChIP Jurkat GSE68976.RUNX1.Jurkat 196 bp overlap

ChIP Jurkat GSE42575.RUNX1.Jurkat 107 bp overlap

ChIP ME-1 GSE117138.RUNX1.ME-1 215 bp overlap

ChIP ME-1_KD GSE128771.RUNX1.ME-1_KD 215 bp overlap

RUNX2 2 datasets

ChIP Karpas-45 GSE151819.RUNX2.Karpas-45 210 bp overlap

ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 500 bp overlap

SMAD2-3 3 datasets

ChIP HGrC1_C134W-TGF GSE138496.SMAD2-3.HGrC1_C134W-TGF 186 bp overlap

ChIP HGrC1_WT-TGF GSE138496.SMAD2-3.HGrC1_WT-TGF 125 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 548 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 483 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 548 bp overlap

SOX11 1 dataset

ChIP GRANT-A519 GSE52146.SOX11.GRANT-A519 90 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 382 bp overlap

STAT3 1 dataset

ChIP MDA-MB-231 GSE152203.STAT3.MDA-MB-231 165 bp overlap

Stat5b 1 dataset

Motif DE_72h DE_72h-Stat5b_MA1625.2 9 bp overlap

ChIP MOLT-3 GSE59657.TAL1.MOLT-3 262 bp overlap

TBX19 1 dataset

Motif DE_72h DE_72h-TBX19_MA0804.2 17 bp overlap

TBX21 1 dataset

ChIP CD4_Th1 GSE62482.TBX21.CD4_Th1 92 bp overlap

Motif DE_72h DE_72h-TBXT_MA0009.2 16 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 274 bp overlap

TEAD1 1 dataset

ChIP HUCCT1 GSE68296.TEAD1.HUCCT1 284 bp overlap

TEAD4 2 datasets

ChIP PC-9_1DF GSE131687.TEAD4.PC-9_1DF 247 bp overlap

ChIP PC-9_2DF GSE131687.TEAD4.PC-9_2DF 267 bp overlap

TRPS1 1 dataset

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

Tcf12 1 dataset

Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap

ChIP ALL GSE145549.YY1.ALL 323 bp overlap

ZNF135 1 dataset

Motif DE_72h DE_72h-ZNF135_MA1587.1 14 bp overlap