chr1 : 111,304,989 – 111,305,695
706 bp 89 TFs 4 linked genes
This 706 bp open chromatin element is linked to 4 target genes and is bound by 89 transcription factors.
Linked Genes
4 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
WDR77 143.9 kb Distal Multiome
ATP5PB 144.1 kb Distal Multiome
DRAM2 165.3 kb Distal Multiome
CEPT1 165.9 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:111,299,989 – 111,310,695
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
89 transcription factors
Source
Cell type
ARNTL 1 dataset
ChIP U2OS_DMSO GSE85096.ARNTL.U2OS_DMSO 239 bp overlap
ASCL1 1 dataset
Motif DE_48h DE_48h-ASCL1_MA1100.3 8 bp overlap
Ascl2 1 dataset
Motif DE_48h DE_48h-Ascl2_MA0816.1 10 bp overlap
BHLHE22 1 dataset
Motif DE_48h DE_48h-BHLHE22_MA1635.2 6 bp overlap
Bhlha15 1 dataset
Motif DE_48h DE_48h-Bhlha15_MA1472.3 8 bp overlap
CBX8 1 dataset
ChIP A-549 ENCSR616MOB.CBX8.A-549 444 bp overlap
CEBPB 1 dataset
ChIP MV4-11 GSE88746.CEBPB.MV4-11 219 bp overlap
CLOCK 1 dataset
ChIP BA40_3 GSE96659.CLOCK.BA40_3 150 bp overlap
CTCF 1 dataset
ChIP THP-1_macrophage_PMA GSE96800.CTCF.THP-1_macrophage_PMA 224 bp overlap
DMRTA1 3 datasets
Motif DE_48h DE_48h-DMRTA1_MA1707.2 10 bp overlap
Motif DE_60h DE_60h-DMRTA1_MA1707.2 10 bp overlap
Motif DE_72h DE_72h-DMRTA1_MA1707.2 10 bp overlap
DMRTC2 2 datasets
Motif DE_48h DE_48h-DMRTC2_MA1479.2 11 bp overlap
Motif DE_72h DE_72h-DMRTC2_MA1479.2 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 270 bp overlap
EZH2 2 datasets
ChIP HCT-116 ENCSR046HGP.EZH2.HCT-116 249 bp overlap
ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 80 bp overlap
FOSB::JUN 2 datasets
Motif DE_48h DE_48h-FOSBJUN_MA1127.1 11 bp overlap
Motif DE_72h DE_72h-FOSBJUN_MA1127.1 11 bp overlap
FOSL2::JUND 2 datasets
Motif DE_48h DE_48h-FOSL2JUND_MA1145.2 10 bp overlap
Motif DE_72h DE_72h-FOSL2JUND_MA1145.2 10 bp overlap
GATA1 1 dataset
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 205 bp overlap
GATA2 2 datasets
ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 241 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 204 bp overlap
GATA3 1 dataset
ChIP MCF-7_E2 GSE29073.GATA3.MCF-7_E2 113 bp overlap
GATA4 8 datasets
ChIP DE DE-GATA4-1 654 bp overlap
ChIP DE DE-GATA4-2 706 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 522 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 282 bp overlap
GATA5 4 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 17 datasets
ChIP AGS GSE51705.GATA6.AGS 175 bp overlap
ChIP DE DE-GATA6-1 641 bp overlap
ChIP DE DE-GATA6-2 706 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 304 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 345 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 597 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 344 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 319 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 187 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 642 bp overlap
ChIP foregut GSE117136.GATA6.foregut 548 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 408 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 231 bp overlap
Gata3 4 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HES6 1 dataset
Motif DE_48h DE_48h-HES6_MA1493.1 10 bp overlap
HIF1A 1 dataset
ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 226 bp overlap
Hic1 1 dataset
Motif DE_48h DE_48h-Hic1_MA0739.2 8 bp overlap
JMJD1C 1 dataset
ChIP HL-60 GSE63484.JMJD1C.HL-60 142 bp overlap
JUN::JUNB 2 datasets
Motif DE_48h DE_48h-JUNJUNB_MA1133.2 11 bp overlap
Motif DE_72h DE_72h-JUNJUNB_MA1133.2 11 bp overlap
KMT2B 2 datasets
ChIP AML GSE112074.KMT2B.AML 454 bp overlap
ChIP AML_OG86 GSE112074.KMT2B.AML_OG86 289 bp overlap
MXI1 1 dataset
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
MYB 2 datasets
ChIP THP-1 GSE90769.MYB.THP-1 452 bp overlap
ChIP THP-1_OG86 GSE90769.MYB.THP-1_OG86 359 bp overlap
MYF5 1 dataset
Motif DE_48h DE_48h-MYF5_MA1641.2 8 bp overlap
MYOD1 1 dataset
Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap
MYOG 1 dataset
Motif DE_48h DE_48h-MYOG_MA0500.3 8 bp overlap
NFIA 1 dataset
Motif DE_48h DE_48h-NFIA_MA0670.2 6 bp overlap
NFIX 1 dataset
Motif DE_48h DE_48h-NFIX_MA0671.2 6 bp overlap
NHLH1 1 dataset
Motif DE_48h DE_48h-NHLH1_MA0048.3 9 bp overlap
NR5A1 2 datasets
Motif DE_48h DE_48h-NR5A1_MA1540.3 12 bp overlap
Motif DE_60h DE_60h-NR5A1_MA1540.3 12 bp overlap
Nanog 4 datasets
Motif DE_36h DE_36h-Nanog_MA2339.1 7 bp overlap
Motif DE_48h DE_48h-Nanog_MA2339.1 7 bp overlap
Motif DE_60h DE_60h-Nanog_MA2339.1 7 bp overlap
Motif DE_72h DE_72h-Nanog_MA2339.1 7 bp overlap
Neurod2 1 dataset
Motif DE_48h DE_48h-Neurod2_MA1993.2 6 bp overlap
OSR2 4 datasets
Motif DE_36h DE_36h-OSR2_MA1646.2 8 bp overlap
Motif DE_48h DE_48h-OSR2_MA1646.2 8 bp overlap
Motif DE_60h DE_60h-OSR2_MA1646.2 8 bp overlap
Motif DE_72h DE_72h-OSR2_MA1646.2 8 bp overlap
Olig2 1 dataset
Motif DE_48h DE_48h-Olig2_MA1997.2 6 bp overlap
POU5F1 3 datasets
ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 195 bp overlap
Motif DE_48h DE_48h-POU5F1_MA1115.2 7 bp overlap
Motif DE_72h DE_72h-POU5F1_MA1115.2 7 bp overlap
PRDM9 2 datasets
Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap
Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap
Pgr 3 datasets
Motif DE_48h DE_48h-Pgr_MA2323.1 17 bp overlap
Motif DE_60h DE_60h-Pgr_MA2323.1 17 bp overlap
Motif DE_72h DE_72h-Pgr_MA2323.1 17 bp overlap
Ptf1A 1 dataset
Motif DE_48h DE_48h-Ptf1A_MA1619.2 8 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 383 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 550 bp overlap
SNAI2 1 dataset
ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 191 bp overlap
SOX10 7 datasets
Motif DE_36h DE_36h-SOX10_MA0442.3 6 bp overlap
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX13 3 datasets
Motif DE_48h DE_48h-SOX13_MA1120.2 7 bp overlap
Motif DE_60h DE_60h-SOX13_MA1120.2 7 bp overlap
Motif DE_72h DE_72h-SOX13_MA1120.2 7 bp overlap
SOX14 3 datasets
Motif DE_48h DE_48h-SOX14_MA1562.2 9 bp overlap
Motif DE_60h DE_60h-SOX14_MA1562.2 9 bp overlap
Motif DE_72h DE_72h-SOX14_MA1562.2 9 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 358 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 660 bp overlap
SOX18 3 datasets
Motif DE_48h DE_48h-SOX18_MA1563.2 8 bp overlap
Motif DE_60h DE_60h-SOX18_MA1563.2 8 bp overlap
Motif DE_72h DE_72h-SOX18_MA1563.2 8 bp overlap
SOX2 4 datasets
Motif DE_48h DE_48h-SOX2_MA0143.5 7 bp overlap
Motif DE_60h DE_60h-SOX2_MA0143.5 7 bp overlap
Motif DE_72h DE_72h-SOX2_MA0143.5 7 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 236 bp overlap
SOX4 9 datasets
Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap
Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap
Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap
Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap
Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap
Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap
Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap
Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap
Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap
SOX8 6 datasets
Motif DE_48h DE_48h-SOX8_MA0868.3 7 bp overlap
Motif DE_48h DE_48h-SOX8_MA0868.3 7 bp overlap
Motif DE_60h DE_60h-SOX8_MA0868.3 7 bp overlap
Motif DE_60h DE_60h-SOX8_MA0868.3 7 bp overlap
Motif DE_72h DE_72h-SOX8_MA0868.3 7 bp overlap
Motif DE_72h DE_72h-SOX8_MA0868.3 7 bp overlap
SOX9 6 datasets
Motif DE_48h DE_48h-SOX9_MA0077.2 8 bp overlap
Motif DE_48h DE_48h-SOX9_MA0077.2 8 bp overlap
Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap
Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap
Motif DE_72h DE_72h-SOX9_MA0077.2 8 bp overlap
Motif DE_72h DE_72h-SOX9_MA0077.2 8 bp overlap
SP1 3 datasets
Motif DE_48h DE_48h-SP1_MA0079.5 9 bp overlap
Motif DE_60h DE_60h-SP1_MA0079.5 9 bp overlap
Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap
SP4 3 datasets
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap
Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap
SP5 3 datasets
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
SPI1 3 datasets
ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 232 bp overlap
ChIP HL-60 ENCFF645GBT 271 bp overlap
ChIP NB4 GSE128834.SPI1.NB4 171 bp overlap
SPIB 3 datasets
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
Motif DE_60h DE_60h-SPIB_MA0081.3 13 bp overlap
Motif DE_72h DE_72h-SPIB_MA0081.3 13 bp overlap
Sox11 3 datasets
Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap
Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap
Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap
Sox17 7 datasets
Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap
Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap
Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap
Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap
Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap
Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap
Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap
Sox3 3 datasets
Motif DE_48h DE_48h-Sox3_MA0514.3 7 bp overlap
Motif DE_60h DE_60h-Sox3_MA0514.3 7 bp overlap
Motif DE_72h DE_72h-Sox3_MA0514.3 7 bp overlap
Sox5 6 datasets
Motif DE_48h DE_48h-Sox5_MA0087.3 8 bp overlap
Motif DE_48h DE_48h-Sox5_MA0087.3 8 bp overlap
Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap
Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap
Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap
Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap
Sox6 6 datasets
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap
Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
Sox7 6 datasets
Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap
Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap
Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap
Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap
Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap
Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap
Spi1 3 datasets
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap
Motif DE_72h DE_72h-Spi1_MA0080.7 13 bp overlap
Stat5a::Stat5b 1 dataset
Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap
TRIM28 1 dataset
ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 143 bp overlap
TRPS1 4 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
Tcf12 1 dataset
Motif DE_48h DE_48h-Tcf12_MA0521.3 6 bp overlap
Twist2 1 dataset
Motif DE_48h DE_48h-Twist2_MA0633.3 6 bp overlap
VEZF1 3 datasets
Motif DE_48h DE_48h-VEZF1_MA1578.2 6 bp overlap
Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap
Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap
ZBTB12 1 dataset
Motif DE_48h DE_48h-ZBTB12_MA1649.2 7 bp overlap
ZBTB18 1 dataset
Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap
ZFP42 3 datasets
Motif DE_48h DE_48h-ZFP42_MA1651.2 13 bp overlap
Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap
Motif DE_72h DE_72h-ZFP42_MA1651.2 13 bp overlap
ZFP69B 1 dataset
ChIP HEK293T GSE78099.ZFP69B.HEK293T 199 bp overlap
ZNF148 3 datasets
Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap
Motif DE_60h DE_60h-ZNF148_MA1653.2 10 bp overlap
Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap
ZNF16 1 dataset
Motif DE_48h DE_48h-ZNF16_MA1654.2 21 bp overlap
ZNF281 3 datasets
Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap
Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
ZNF324 1 dataset
Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap
ZNF382 4 datasets
Motif DE_36h DE_36h-ZNF382_MA1594.1 24 bp overlap
Motif DE_48h DE_48h-ZNF382_MA1594.1 24 bp overlap
Motif DE_60h DE_60h-ZNF382_MA1594.1 24 bp overlap
Motif DE_72h DE_72h-ZNF382_MA1594.1 24 bp overlap
ZNF418 4 datasets
Motif DE_36h DE_36h-ZNF418_MA1980.1 15 bp overlap
Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap
Motif DE_60h DE_60h-ZNF418_MA1980.1 15 bp overlap
Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap
ZNF667 4 datasets
Motif DE_36h DE_36h-ZNF667_MA1984.2 11 bp overlap
Motif DE_48h DE_48h-ZNF667_MA1984.2 11 bp overlap
Motif DE_60h DE_60h-ZNF667_MA1984.2 11 bp overlap
Motif DE_72h DE_72h-ZNF667_MA1984.2 11 bp overlap
ZNF684 2 datasets
Motif DE_48h DE_48h-ZNF684_MA1600.2 14 bp overlap
Motif DE_60h DE_60h-ZNF684_MA1600.2 14 bp overlap
ZNF816 3 datasets
Motif DE_48h DE_48h-ZNF816_MA1719.2 15 bp overlap
Motif DE_60h DE_60h-ZNF816_MA1719.2 15 bp overlap
Motif DE_72h DE_72h-ZNF816_MA1719.2 15 bp overlap
Huangfu Lab · Publications · Resources · Contact