chr5 : 33,929,045 – 33,930,097
1,052 bp 81 TFs 3 linked genes
This 1.1 kb open chromatin element is linked to RXFP3, ADAMTS12, and AMACR and is bound by 81 transcription factors.
Linked Genes
3 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
RXFP3 6.3 kb Proximal Proximity
ADAMTS12 37.6 kb Distal Multiome+HiCAR
AMACR 78.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:33,924,045 – 33,935,097
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
81 transcription factors
Source
Cell type
ATF7 2 datasets
ChIP GM12878 ENCFF037PYH 96 bp overlap
ChIP GM12878 ENCSR014YCR.ATF7.GM12878 138 bp overlap
Ahr::Arnt 2 datasets
Motif DE_60h DE_60h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap
BHLHE40 3 datasets
ChIP GM12878 ENCFF521IZR 120 bp overlap
ChIP GM12878 ENCSR517QHU.BHLHE40.GM12878 137 bp overlap
ChIP GM12878 ENCSR987MTA.BHLHE40.GM12878 66 bp overlap
BRD3 1 dataset
ChIP H-1_DE GSE126661.BRD3.H-1_DE 323 bp overlap
CHD1 1 dataset
ChIP GM12878 ENCFF566UBH 142 bp overlap
DMRTA1 2 datasets
Motif DE_60h DE_60h-DMRTA1_MA1707.2 10 bp overlap
Motif DE_72h DE_72h-DMRTA1_MA1707.2 10 bp overlap
DMRTA2 2 datasets
Motif DE_60h DE_60h-DMRTA2_MA1478.2 6 bp overlap
Motif DE_72h DE_72h-DMRTA2_MA1478.2 6 bp overlap
DMRTC2 2 datasets
Motif DE_60h DE_60h-DMRTC2_MA1479.2 11 bp overlap
Motif DE_72h DE_72h-DMRTC2_MA1479.2 11 bp overlap
DPF2 1 dataset
ChIP GM12878 ENCSR509FWH.DPF2.GM12878 69 bp overlap
DUX4 2 datasets
Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap
Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap
ERF::FIGLA 1 dataset
Motif DE_60h DE_60h-ERFFIGLA_MA1934.2 13 bp overlap
ETV2::FIGLA 1 dataset
Motif DE_60h DE_60h-ETV2FIGLA_MA1941.2 13 bp overlap
ETV2::HOXB13 2 datasets
Motif DE_60h DE_60h-ETV2HOXB13_MA1943.2 13 bp overlap
Motif DE_72h DE_72h-ETV2HOXB13_MA1943.2 13 bp overlap
ETV5::FIGLA 1 dataset
Motif DE_60h DE_60h-ETV5FIGLA_MA1945.2 14 bp overlap
FEZF2 2 datasets
Motif DE_60h DE_60h-FEZF2_MA2341.1 8 bp overlap
Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap
FIGLA 2 datasets
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 904 bp overlap
ChIP DE DE-FOXA2-2 791 bp overlap
FOXD3 2 datasets
Motif DE_60h DE_60h-FOXD3_MA0041.3 14 bp overlap
Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap
FOXE1 2 datasets
Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap
Motif DE_72h DE_72h-FOXE1_MA1487.3 12 bp overlap
FOXK2 1 dataset
ChIP GM12878 ENCSR861JUQ.FOXK2.GM12878 72 bp overlap
GATA2 3 datasets
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
GATA4 8 datasets
ChIP DE DE-GATA4-1 907 bp overlap
ChIP DE DE-GATA4-2 892 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 564 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 732 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 683 bp overlap
GATA5 5 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 17 datasets
ChIP DE DE-GATA6-1 775 bp overlap
ChIP DE DE-GATA6-2 901 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 390 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 651 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 457 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 737 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 730 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 459 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 329 bp overlap
ChIP foregut GSE117136.GATA6.foregut 757 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 408 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 379 bp overlap
GRHL1 5 datasets
Motif DE_48h DE_48h-GRHL1_MA0647.2 10 bp overlap
Motif DE_60h DE_60h-GRHL1_MA0647.2 10 bp overlap
Motif DE_60h DE_60h-GRHL1_MA0647.2 10 bp overlap
Motif DE_72h DE_72h-GRHL1_MA0647.2 10 bp overlap
Motif DE_72h DE_72h-GRHL1_MA0647.2 10 bp overlap
GRHL2 5 datasets
Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap
Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap
Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap
Motif DE_72h DE_72h-GRHL2_MA1105.3 8 bp overlap
Motif DE_72h DE_72h-GRHL2_MA1105.3 8 bp overlap
Gata3 5 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
Gfi1B 1 dataset
Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap
Gli1 3 datasets
Motif DE_48h DE_48h-Gli1_MA1990.2 10 bp overlap
Motif DE_60h DE_60h-Gli1_MA1990.2 10 bp overlap
Motif DE_72h DE_72h-Gli1_MA1990.2 10 bp overlap
Gli2 3 datasets
Motif DE_48h DE_48h-Gli2_MA0734.4 9 bp overlap
Motif DE_60h DE_60h-Gli2_MA0734.4 9 bp overlap
Motif DE_72h DE_72h-Gli2_MA0734.4 9 bp overlap
HIC2 1 dataset
Motif DE_60h DE_60h-HIC2_MA0738.2 6 bp overlap
HLF 2 datasets
Motif DE_60h DE_60h-HLF_MA0043.4 9 bp overlap
Motif DE_72h DE_72h-HLF_MA0043.4 9 bp overlap
IKZF1 1 dataset
ChIP GM12878 ENCFF824TGK 145 bp overlap
IKZF2 1 dataset
ChIP GM12878 ENCFF238LYK 79 bp overlap
IRF3 1 dataset
ChIP GM12878 ENCFF530XSI 118 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 289 bp overlap
KDM1A 1 dataset
ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 285 bp overlap
Lhx3 2 datasets
Motif DE_60h DE_60h-Lhx3_MA0135.2 12 bp overlap
Motif DE_72h DE_72h-Lhx3_MA0135.2 12 bp overlap
MEIS1 5 datasets
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MEIS3 2 datasets
Motif DE_60h DE_60h-MEIS3_MA0775.2 7 bp overlap
Motif DE_72h DE_72h-MEIS3_MA0775.2 7 bp overlap
MLLT1 2 datasets
ChIP GM12878 ENCFF995GXC 279 bp overlap
ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 370 bp overlap
MTA2 2 datasets
ChIP GM12878 ENCFF615CWQ 84 bp overlap
ChIP GM12878 ENCSR293QAR.MTA2.GM12878 217 bp overlap
MYF6 2 datasets
Motif DE_60h DE_60h-MYF6_MA0667.1 10 bp overlap
Motif DE_72h DE_72h-MYF6_MA0667.1 10 bp overlap
Mecom 5 datasets
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
NBN 1 dataset
ChIP GM12878 ENCSR278SQL.NBN.GM12878 67 bp overlap
NFIC 1 dataset
ChIP GM12878 ENCSR000BRN.NFIC.GM12878 86 bp overlap
NKX2-2 2 datasets
Motif DE_60h DE_60h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_72h DE_72h-NKX2-2_MA1645.2 8 bp overlap
NOTCH3 1 dataset
ChIP TALL-1_GSI GSE104261.NOTCH3.TALL-1_GSI 178 bp overlap
NR3C1 1 dataset
ChIP MCF-7_E2_Dex GSE81510.NR3C1.MCF-7_E2_Dex 202 bp overlap
Nr1h3::Rxra 2 datasets
Motif DE_60h DE_60h-Nr1h3Rxra_MA0494.2 16 bp overlap
Motif DE_72h DE_72h-Nr1h3Rxra_MA0494.2 16 bp overlap
Pou5f1::Sox2 2 datasets
Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_72h DE_72h-Pou5f1Sox2_MA0142.1 15 bp overlap
RELA 1 dataset
ChIP GM12878 ENCSR000EAG.RELA.GM12878 64 bp overlap
RELB 2 datasets
ChIP GM12878 ENCFF217ADF 137 bp overlap
ChIP GM12878 ENCSR387QUV.RELB.GM12878 178 bp overlap
REST 1 dataset
ChIP LNCaP GSE119385.REST.LNCaP 78 bp overlap
RFX3 2 datasets
Motif DE_60h DE_60h-RFX3_MA0798.3 16 bp overlap
Motif DE_72h DE_72h-RFX3_MA0798.3 16 bp overlap
SIX1 3 datasets
Motif DE_60h DE_60h-SIX1_MA1118.2 9 bp overlap
Motif DE_60h DE_60h-SIX1_MA1118.2 9 bp overlap
Motif DE_72h DE_72h-SIX1_MA1118.2 9 bp overlap
SIX2 3 datasets
Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap
Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap
Motif DE_72h DE_72h-SIX2_MA1119.2 11 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 905 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 273 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 682 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 780 bp overlap
SOX10 2 datasets
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 536 bp overlap
SREBF1 2 datasets
Motif DE_60h DE_60h-SREBF1_MA0595.1 10 bp overlap
Motif DE_72h DE_72h-SREBF1_MA0595.1 10 bp overlap
SREBF2 2 datasets
Motif DE_60h DE_60h-SREBF2_MA0596.1 10 bp overlap
Motif DE_72h DE_72h-SREBF2_MA0596.1 10 bp overlap
TARDBP 1 dataset
ChIP GM12878 ENCSR412QBS.TARDBP.GM12878 71 bp overlap
TBX21 1 dataset
ChIP GM12878 ENCSR739IHN.TBX21.GM12878 272 bp overlap
TCF4 2 datasets
Motif DE_60h DE_60h-TCF4_MA0830.3 8 bp overlap
Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap
TEAD1 2 datasets
Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap
Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap
TEAD3 2 datasets
Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap
Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap
TFAP2C 1 dataset
ChIP HCC1954 GSE126897.TFAP2C.HCC1954 201 bp overlap
TFAP4::ETV1 1 dataset
Motif DE_60h DE_60h-TFAP4ETV1_MA1966.2 13 bp overlap
TRPS1 5 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
USF1 2 datasets
Motif DE_60h DE_60h-USF1_MA0093.4 10 bp overlap
Motif DE_72h DE_72h-USF1_MA0093.4 10 bp overlap
VEZF1 3 datasets
Motif DE_48h DE_48h-VEZF1_MA1578.2 6 bp overlap
Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap
Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap
ZEB1 2 datasets
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZFP14 2 datasets
Motif DE_60h DE_60h-ZFP14_MA1972.1 15 bp overlap
Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap
ZKSCAN5 1 dataset
Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF136 1 dataset
Motif DE_60h DE_60h-ZNF136_MA1588.1 15 bp overlap
ZNF354A 3 datasets
Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_72h DE_72h-ZNF354A_MA1978.2 20 bp overlap
ZNF680 1 dataset
Motif DE_60h DE_60h-ZNF680_MA1729.2 11 bp overlap
ZNF740 3 datasets
Motif DE_48h DE_48h-ZNF740_MA0753.3 10 bp overlap
Motif DE_60h DE_60h-ZNF740_MA0753.3 10 bp overlap
Motif DE_72h DE_72h-ZNF740_MA0753.3 10 bp overlap
Zfx 5 datasets
Motif DE_48h DE_48h-Zfx_MA0146.3 10 bp overlap
Motif DE_60h DE_60h-Zfx_MA0146.3 10 bp overlap
Motif DE_60h DE_60h-Zfx_MA0146.3 10 bp overlap
Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap
Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap
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