chr4 : 84,501,767 – 84,502,114
347 bp 54 TFs 1 linked gene
This 347 bp open chromatin element is linked to NKX6-1 and is bound by 54 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
NKX6-1 4.8 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:84,496,767 – 84,507,114
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
54 transcription factors
Source
Cell type
AR 1 dataset
ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 159 bp overlap
ASCL1 1 dataset
Motif DE_12h DE_12h-ASCL1_MA1631.2 9 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 152 bp overlap
BCOR 2 datasets
ChIP WA01 GSE104690.BCOR.WA01 347 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 219 bp overlap
BMPR1A 1 dataset
ChIP HUVEC-C GSE60156.BMPR1A.HUVEC-C 200 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 347 bp overlap
BRD2 2 datasets
ChIP K-562_iBET-BD1-IFNG GSE138084.BRD2.K-562_iBET-BD1-IFNG 201 bp overlap
ChIP MV4-11_IBET151_500nM GSE120715.BRD2.MV4-11_IBET151_500nM 250 bp overlap
BRD4 1 dataset
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 331 bp overlap
CBX4 1 dataset
ChIP hMSC GSE117084.CBX4.hMSC 310 bp overlap
CBX7 1 dataset
ChIP lymphocyte_DMSO GSE110139.CBX7.lymphocyte_DMSO 161 bp overlap
CBX8 1 dataset
ChIP K-562 ENCSR000ATW.CBX8.K-562 322 bp overlap
CTCF 1 dataset
ChIP neural ENCSR822CEA.CTCF.neural 173 bp overlap
ERF::FOXO1 1 dataset
Motif DE_12h DE_12h-ERFFOXO1_MA1936.2 12 bp overlap
ESR1 1 dataset
ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 326 bp overlap
EZH1 1 dataset
ChIP ProEs_SHEZH2 GSE59087.EZH1.ProEs_SHEZH2 136 bp overlap
EZH2 22 datasets
ChIP GM23338 ENCFF613YON 102 bp overlap
ChIP GM23338 ENCFF613YON 307 bp overlap
ChIP H1 ENCFF232NZA 347 bp overlap
ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 347 bp overlap
ChIP Hep-G2 ENCSR000ARI.EZH2.Hep-G2 347 bp overlap
ChIP LNCaP GSE39459.EZH2.LNCaP 169 bp overlap
ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 347 bp overlap
ChIP ProEs_SHCTR GSE59087.EZH2.ProEs_SHCTR 202 bp overlap
ChIP SK-N-SH ENCFF657FZK 277 bp overlap
ChIP astrocyte ENCFF365JTP 347 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 347 bp overlap
ChIP fibroblast of dermis ENCFF029VZK 347 bp overlap
ChIP fibroblast of lung ENCFF479BAW 331 bp overlap
ChIP hepatocyte ENCFF118DKH 82 bp overlap
ChIP hepatocyte ENCFF552DZB 347 bp overlap
ChIP keratinocyte ENCFF070STK 301 bp overlap
ChIP keratinocyte ENCFF070STK 99 bp overlap
ChIP mammary epithelial cell ENCFF224GAI 148 bp overlap
ChIP neural cell ENCFF610EPB 339 bp overlap
ChIP neural progenitor cell ENCFF018MKA 347 bp overlap
ChIP neural progenitor cell ENCFF472NFV 347 bp overlap
ChIP skeletal muscle myoblast ENCFF338LNF 262 bp overlap
FIGLA 1 dataset
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
FOXK1 1 dataset
ChIP WTC11 ENCFF875IGU 305 bp overlap
FOXO1::ELF1 1 dataset
Motif DE_12h DE_12h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 150 bp overlap
GATA2 1 dataset
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 242 bp overlap
GATA6 1 dataset
ChIP DE_D1 S41-DE-d1-GATA6-exp2 185 bp overlap
GTF3C2 1 dataset
ChIP H9 GSE94418.GTF3C2.H9 237 bp overlap
HEXIM1 1 dataset
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 218 bp overlap
JARID2 2 datasets
ChIP AMIPS6 GSE48516.JARID2.AMIPS6 347 bp overlap
ChIP MRC-5_IPS25 GSE48516.JARID2.MRC-5_IPS25 347 bp overlap
JUN 2 datasets
ChIP 786-O GSE86092.JUN.786-O 329 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 256 bp overlap
MGA::EVX1 1 dataset
Motif DE_12h DE_12h-MGAEVX1_MA1960.2 11 bp overlap
MYC 1 dataset
ChIP endothelial_umbilical-vein ENCSR000DLU.MYC.endothelial_umbilical-vein 100 bp overlap
MYCN 2 datasets
ChIP COG-N-415 GSE138295.MYCN.COG-N-415 347 bp overlap
ChIP LA-N-5 GSE138295.MYCN.LA-N-5 347 bp overlap
MYOD1 2 datasets
Motif DE_12h DE_12h-MYOD1_MA0499.3 9 bp overlap
ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 193 bp overlap
NANOG 1 dataset
ChIP HUES-8 GSE109524.NANOG.HUES-8 347 bp overlap
OGG1 1 dataset
ChIP HEK293 GSE89017.OGG1.HEK293 276 bp overlap
PCGF2 1 dataset
ChIP fibroblast_OHT GSE55605.PCGF2.fibroblast_OHT 240 bp overlap
POLR2A 7 datasets
ChIP esophagus muscularis mucosa ENCFF432ZCY 347 bp overlap
ChIP esophagus muscularis mucosa ENCFF432ZCY 188 bp overlap
ChIP esophagus muscularis mucosa ENCFF759BBR 152 bp overlap
ChIP esophagus muscularis mucosa ENCFF791ZXN 257 bp overlap
ChIP gastroesophageal sphincter ENCFF043KAM 273 bp overlap
ChIP gastroesophageal sphincter ENCFF238INU 347 bp overlap
ChIP neural cell ENCFF604SPB 298 bp overlap
POU5F1 4 datasets
ChIP BG03 GSE21614.POU5F1.BG03 207 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 347 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 347 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 246 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 338 bp overlap
RELA 2 datasets
ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 282 bp overlap
ChIP SGBS GSE64233.RELA.SGBS 211 bp overlap
RNF2 6 datasets
ChIP H1 ENCFF239FFS 347 bp overlap
ChIP K-562 ENCSR076YPO.RNF2.K-562 133 bp overlap
ChIP K-562 ENCSR820GND.RNF2.K-562 220 bp overlap
ChIP SYO-1_shCt GSE139053.RNF2.SYO-1_shCt 163 bp overlap
ChIP SYO-1_shRING1A-B GSE139053.RNF2.SYO-1_shRING1A-B 164 bp overlap
ChIP SYO-1_shRING1A-B GSE139053.RNF2.SYO-1_shRING1A-B 90 bp overlap
RUNX1 2 datasets
ChIP Jurkat GSE85524.RUNX1.Jurkat 284 bp overlap
ChIP epididymis_HEE GSE109061.RUNX1.epididymis_HEE 182 bp overlap
RYBP 1 dataset
ChIP WA01 GSE104690.RYBP.WA01 347 bp overlap
SAP30 1 dataset
ChIP WA01 ENCSR000ATR.SAP30.WA01 170 bp overlap
SIN3A 1 dataset
ChIP WA01 ENCSR000EBO.SIN3A.WA01 169 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 272 bp overlap
SMAD2_3 1 dataset
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 293 bp overlap
SUZ12 7 datasets
ChIP GM12878 ENCSR091BOQ.SUZ12.GM12878 51 bp overlap
ChIP H1 ENCFF507HGF 264 bp overlap
ChIP H1 ENCFF881NFR 347 bp overlap
ChIP K-562 ENCSR000AUC.SUZ12.K-562 184 bp overlap
ChIP NT2/D1 ENCFF574SXS 347 bp overlap
ChIP WA01 ENCSR000EUQ.SUZ12.WA01 298 bp overlap
ChIP hMSC GSE125166.SUZ12.hMSC 201 bp overlap
TAF15 1 dataset
ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 170 bp overlap
TCF12 2 datasets
ChIP WA01 ENCSR000BIT.TCF12.WA01 175 bp overlap
ChIP WA01 ENCSR000BIT.TCF12.WA01 87 bp overlap
TCF4 1 dataset
Motif DE_12h DE_12h-TCF4_MA0830.3 8 bp overlap
TGIF2 1 dataset
ChIP WTC11 ENCFF649SHI 326 bp overlap
ZEB1 1 dataset
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
ZNF317 1 dataset
Motif DE_12h DE_12h-ZNF317_MA1593.2 8 bp overlap
ZNF354C 1 dataset
Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap
ZNF549 1 dataset
Motif DE_12h DE_12h-ZNF549_MA1728.2 8 bp overlap
ZNF891 1 dataset
ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 165 bp overlap
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