chr3 : 124,757,599 – 124,758,508

909 bp 59 TFs 4 linked genes

This 909 bp open chromatin element is linked to 4 target genes and is bound by 59 transcription factors.

Linked Genes

4 genes

Gene	Dist. to TSS	Distance	Link type
ITGB5-AS1	23.2 kb	Distal	Multiome
UMPS	27.5 kb	Distal	Multiome
ITGB5	129.4 kb	Distal	Multiome+HiCAR
HEG1	298.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

59 transcription factors

ARNTL 1 dataset

ChIP U2OS_DMOG GSE85096.ARNTL.U2OS_DMOG 209 bp overlap

BCL3 1 dataset

ChIP A-549 ENCSR000BQH.BCL3.A-549 270 bp overlap

BCL6B 2 datasets

Motif DE_24h DE_24h-BCL6B_MA0731.1 17 bp overlap

Motif DE_72h DE_72h-BCL6B_MA0731.1 17 bp overlap

BRD4 1 dataset

ChIP HAP1 GSE108387.BRD4.HAP1 275 bp overlap

CREB1 1 dataset

Motif DE_72h DE_72h-CREB1_MA0018.5 8 bp overlap

CTCF 1 dataset

Motif DE_72h DE_72h-CTCF_MA1930.2 33 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF335XTP 251 bp overlap

ChIP BLaER1 ENCFF364PUR 51 bp overlap

ETV2::DRGX 2 datasets

Motif DE_12h DE_12h-ETV2DRGX_MA1940.2 12 bp overlap

Motif DE_72h DE_72h-ETV2DRGX_MA1940.2 12 bp overlap

ETV5::DRGX 2 datasets

Motif DE_12h DE_12h-ETV5DRGX_MA1944.2 12 bp overlap

Motif DE_72h DE_72h-ETV5DRGX_MA1944.2 12 bp overlap

FLI1::DRGX 2 datasets

Motif DE_12h DE_12h-FLI1DRGX_MA1949.2 14 bp overlap

Motif DE_72h DE_72h-FLI1DRGX_MA1949.2 14 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 282 bp overlap

GATA6 2 datasets

ChIP DE DE-GATA6-2 289 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 306 bp overlap

HOXB13 2 datasets

Motif DE_24h DE_24h-HOXB13_MA0901.3 9 bp overlap

Motif DE_72h DE_72h-HOXB13_MA0901.3 9 bp overlap

Hoxa13 2 datasets

Motif DE_24h DE_24h-Hoxa13_MA0650.4 8 bp overlap

Motif DE_72h DE_72h-Hoxa13_MA0650.4 8 bp overlap

IRF3 2 datasets

Motif DE_24h DE_24h-IRF3_MA1418.2 17 bp overlap

Motif DE_72h DE_72h-IRF3_MA1418.2 17 bp overlap

JUN 4 datasets

Motif DE_72h DE_72h-JUN_MA0488.2 10 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 518 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 401 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 277 bp overlap

KLF1 1 dataset

Motif DE_72h DE_72h-KLF1_MA0493.3 8 bp overlap

KLF10 1 dataset

Motif DE_72h DE_72h-KLF10_MA1511.2 9 bp overlap

KLF11 1 dataset

Motif DE_72h DE_72h-KLF11_MA1512.2 10 bp overlap

KLF12 1 dataset

Motif DE_72h DE_72h-KLF12_MA0742.2 9 bp overlap

KLF14 1 dataset

Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap

KLF15 1 dataset

Motif DE_72h DE_72h-KLF15_MA1513.2 8 bp overlap

KLF16 1 dataset

Motif DE_72h DE_72h-KLF16_MA0741.1 11 bp overlap

KLF2 1 dataset

Motif DE_72h DE_72h-KLF2_MA1515.2 8 bp overlap

KLF3 1 dataset

ChIP keratinocyte GSE140991.KLF3.keratinocyte 215 bp overlap

KLF4 1 dataset

Motif DE_72h DE_72h-KLF4_MA0039.5 8 bp overlap

KLF5 1 dataset

Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap

KLF7 1 dataset

Motif DE_72h DE_72h-KLF7_MA1959.2 8 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 256 bp overlap

NFATC3 2 datasets

Motif DE_24h DE_24h-NFATC3_MA0625.3 6 bp overlap

Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap

NFATC4 2 datasets

Motif DE_24h DE_24h-NFATC4_MA1525.3 9 bp overlap

Motif DE_72h DE_72h-NFATC4_MA1525.3 9 bp overlap

NR2C2 1 dataset

Motif DE_72h DE_72h-NR2C2_MA0504.2 14 bp overlap

Nfat5 2 datasets

Motif DE_24h DE_24h-Nfat5_MA0606.3 8 bp overlap

Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap

Nfatc1 2 datasets

Motif DE_24h DE_24h-Nfatc1_MA0624.3 6 bp overlap

Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 2 datasets

Motif DE_24h DE_24h-Nfatc2_MA0152.3 8 bp overlap

Motif DE_72h DE_72h-Nfatc2_MA0152.3 8 bp overlap

PATZ1 1 dataset

Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 245 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 327 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 306 bp overlap

RBPJ 2 datasets

Motif DE_24h DE_24h-RBPJ_MA1116.2 6 bp overlap

Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 272 bp overlap

SOX13 2 datasets

Motif DE_12h DE_12h-SOX13_MA1120.2 7 bp overlap

Motif DE_72h DE_72h-SOX13_MA1120.2 7 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 266 bp overlap

SOX2 2 datasets

Motif DE_12h DE_12h-SOX2_MA0143.5 7 bp overlap

Motif DE_72h DE_72h-SOX2_MA0143.5 7 bp overlap

SOX9 2 datasets

Motif DE_12h DE_12h-SOX9_MA0077.2 8 bp overlap

Motif DE_72h DE_72h-SOX9_MA0077.2 8 bp overlap

SP1 1 dataset

Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap

SP2 1 dataset

Motif DE_72h DE_72h-SP2_MA0516.3 9 bp overlap

SP3 1 dataset

Motif DE_72h DE_72h-SP3_MA0746.3 11 bp overlap

SP4 1 dataset

Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap

SP9 1 dataset

Motif DE_72h DE_72h-SP9_MA1564.2 10 bp overlap

Sox17 2 datasets

Motif DE_12h DE_12h-Sox17_MA0078.3 10 bp overlap

Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap

Sox3 2 datasets

Motif DE_12h DE_12h-Sox3_MA0514.3 7 bp overlap

Motif DE_72h DE_72h-Sox3_MA0514.3 7 bp overlap

TBP 2 datasets

Motif DE_24h DE_24h-TBP_MA0108.3 7 bp overlap

Motif DE_72h DE_72h-TBP_MA0108.3 7 bp overlap

TEAD1 2 datasets

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap

TEAD2 2 datasets

Motif DE_12h DE_12h-TEAD2_MA1121.2 7 bp overlap

Motif DE_72h DE_72h-TEAD2_MA1121.2 7 bp overlap

TEAD3 2 datasets

Motif DE_12h DE_12h-TEAD3_MA0808.1 8 bp overlap

Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap

TEAD4 2 datasets

Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap

Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap

YY1 1 dataset

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 107 bp overlap

ZNF148 1 dataset

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap