chr3 : 69,651,396 – 69,652,499
1,103 bp 88 TFs 1 linked gene
This 1.1 kb open chromatin element is linked to FRMD4B and is bound by 88 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
FRMD4B 109.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:69,646,396 – 69,657,499
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
88 transcription factors
Source
Cell type
BARHL1 2 datasets
Motif DE_48h DE_48h-BARHL1_MA0877.4 6 bp overlap
Motif DE_60h DE_60h-BARHL1_MA0877.4 6 bp overlap
BARHL2 2 datasets
Motif DE_48h DE_48h-BARHL2_MA0635.2 6 bp overlap
Motif DE_60h DE_60h-BARHL2_MA0635.2 6 bp overlap
Bach1::Mafk 2 datasets
Motif DE_60h DE_60h-Bach1Mafk_MA0591.2 12 bp overlap
Motif DE_72h DE_72h-Bach1Mafk_MA0591.2 12 bp overlap
DPRX 3 datasets
Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap
Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap
Motif DE_72h DE_72h-DPRX_MA1480.2 9 bp overlap
Ddit3::Cebpa 2 datasets
Motif DE_48h DE_48h-Ddit3Cebpa_MA0019.2 10 bp overlap
Motif DE_60h DE_60h-Ddit3Cebpa_MA0019.2 10 bp overlap
EOMES 4 datasets
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap
Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 454 bp overlap
ERF::FOXO1 3 datasets
Motif DE_48h DE_48h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_60h DE_60h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_72h DE_72h-ERFFOXO1_MA1936.2 12 bp overlap
ETV5::FOXO1 3 datasets
Motif DE_48h DE_48h-ETV5FOXO1_MA1947.2 10 bp overlap
Motif DE_60h DE_60h-ETV5FOXO1_MA1947.2 10 bp overlap
Motif DE_72h DE_72h-ETV5FOXO1_MA1947.2 10 bp overlap
FEZF2 1 dataset
Motif DE_60h DE_60h-FEZF2_MA2341.1 8 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 727 bp overlap
ChIP DE DE-FOXA2-2 653 bp overlap
FOXO1::ELK3 3 datasets
Motif DE_48h DE_48h-FOXO1ELK3_MA1955.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1ELK3_MA1955.2 13 bp overlap
Motif DE_72h DE_72h-FOXO1ELK3_MA1955.2 13 bp overlap
GATA4 8 datasets
ChIP DE DE-GATA4-1 777 bp overlap
ChIP DE DE-GATA4-2 952 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 352 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 410 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 333 bp overlap
GATA5 3 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 16 datasets
ChIP DE DE-GATA6-1 701 bp overlap
ChIP DE DE-GATA6-2 1019 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 656 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 532 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 381 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 970 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 620 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 638 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 766 bp overlap
ChIP foregut GSE117136.GATA6.foregut 454 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 335 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 323 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 372 bp overlap
Gata3 3 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HDAC2 2 datasets
ChIP RH4_DMSO-6H GSE116344.HDAC2.RH4_DMSO-6H 205 bp overlap
ChIP pre-B-cell GSE107886.HDAC2.pre-B-cell 131 bp overlap
HDAC3 1 dataset
ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 225 bp overlap
Hand1 2 datasets
Motif DE_48h DE_48h-Hand1_MA2123.1 9 bp overlap
Motif DE_60h DE_60h-Hand1_MA2123.1 9 bp overlap
Hand1::Tcf3 3 datasets
Motif DE_48h DE_48h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_72h DE_72h-Hand1Tcf3_MA0092.2 9 bp overlap
Hmga1 1 dataset
Motif DE_60h DE_60h-Hmga1_MA2124.1 8 bp overlap
IRF3 1 dataset
Motif DE_60h DE_60h-IRF3_MA1418.2 17 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 367 bp overlap
KLF1 1 dataset
Motif DE_60h DE_60h-KLF1_MA0493.3 8 bp overlap
KLF10 1 dataset
Motif DE_60h DE_60h-KLF10_MA1511.2 9 bp overlap
KLF11 1 dataset
Motif DE_60h DE_60h-KLF11_MA1512.2 10 bp overlap
KLF14 1 dataset
Motif DE_60h DE_60h-KLF14_MA0740.2 9 bp overlap
KLF16 1 dataset
Motif DE_60h DE_60h-KLF16_MA0741.1 11 bp overlap
KLF2 1 dataset
Motif DE_60h DE_60h-KLF2_MA1515.2 8 bp overlap
KLF4 2 datasets
Motif DE_60h DE_60h-KLF4_MA0039.5 8 bp overlap
ChIP HAP1 GSE130417.KLF4.HAP1 267 bp overlap
KLF5 1 dataset
Motif DE_60h DE_60h-KLF5_MA0599.1 10 bp overlap
MAF::NFE2 2 datasets
Motif DE_60h DE_60h-MAFNFE2_MA0501.2 11 bp overlap
Motif DE_72h DE_72h-MAFNFE2_MA0501.2 11 bp overlap
MAFG::NFE2L1 2 datasets
Motif DE_60h DE_60h-MAFGNFE2L1_MA0089.3 11 bp overlap
Motif DE_72h DE_72h-MAFGNFE2L1_MA0089.3 11 bp overlap
MAFK 1 dataset
Motif DE_60h DE_60h-MAFK_MA0496.4 10 bp overlap
MGA 3 datasets
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap
Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap
MTA2 1 dataset
ChIP RH4 GSE155861.MTA2.RH4 180 bp overlap
MYBL2 2 datasets
Motif DE_48h DE_48h-MYBL2_MA0777.1 15 bp overlap
Motif DE_60h DE_60h-MYBL2_MA0777.1 15 bp overlap
Mafg 3 datasets
Motif DE_60h DE_60h-Mafg_MA0659.4 12 bp overlap
Motif DE_60h DE_60h-Mafg_MA0659.4 12 bp overlap
Motif DE_72h DE_72h-Mafg_MA0659.4 12 bp overlap
NFIC::TLX1 3 datasets
Motif DE_48h DE_48h-NFICTLX1_MA0119.1 14 bp overlap
Motif DE_60h DE_60h-NFICTLX1_MA0119.1 14 bp overlap
Motif DE_72h DE_72h-NFICTLX1_MA0119.1 14 bp overlap
PATZ1 1 dataset
Motif DE_60h DE_60h-PATZ1_MA1961.2 11 bp overlap
POU4F1 2 datasets
Motif DE_48h DE_48h-POU4F1_MA0790.2 12 bp overlap
Motif DE_60h DE_60h-POU4F1_MA0790.2 12 bp overlap
POU4F2 2 datasets
Motif DE_48h DE_48h-POU4F2_MA0683.2 15 bp overlap
Motif DE_60h DE_60h-POU4F2_MA0683.2 15 bp overlap
POU4F3 2 datasets
Motif DE_48h DE_48h-POU4F3_MA0791.2 12 bp overlap
Motif DE_60h DE_60h-POU4F3_MA0791.2 12 bp overlap
Pgr 3 datasets
Motif DE_48h DE_48h-Pgr_MA2323.1 17 bp overlap
Motif DE_60h DE_60h-Pgr_MA2323.1 17 bp overlap
Motif DE_72h DE_72h-Pgr_MA2323.1 17 bp overlap
RREB1 1 dataset
Motif DE_60h DE_60h-RREB1_MA0073.2 19 bp overlap
Rhox11 2 datasets
Motif DE_48h DE_48h-Rhox11_MA0629.2 9 bp overlap
Motif DE_60h DE_60h-Rhox11_MA0629.2 9 bp overlap
SCRT1 3 datasets
Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap
Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap
Motif DE_72h DE_72h-SCRT1_MA0743.3 10 bp overlap
SCRT2 3 datasets
Motif DE_48h DE_48h-SCRT2_MA0744.3 10 bp overlap
Motif DE_60h DE_60h-SCRT2_MA0744.3 10 bp overlap
Motif DE_72h DE_72h-SCRT2_MA0744.3 10 bp overlap
SMAD2 2 datasets
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 872 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 636 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 492 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 303 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 497 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 771 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 579 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 162 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 592 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 625 bp overlap
SPI1 2 datasets
ChIP K-562 ENCSR000BGW.SPI1.K-562 103 bp overlap
ChIP OCI-Ly7 GSE69558.SPI1.OCI-Ly7 146 bp overlap
SREBF1 3 datasets
Motif DE_48h DE_48h-SREBF1_MA0595.1 10 bp overlap
Motif DE_60h DE_60h-SREBF1_MA0595.1 10 bp overlap
Motif DE_72h DE_72h-SREBF1_MA0595.1 10 bp overlap
SREBF2 3 datasets
Motif DE_48h DE_48h-SREBF2_MA0596.1 10 bp overlap
Motif DE_60h DE_60h-SREBF2_MA0596.1 10 bp overlap
Motif DE_72h DE_72h-SREBF2_MA0596.1 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 247 bp overlap
TBX19 1 dataset
Motif DE_60h DE_60h-TBX19_MA0804.2 17 bp overlap
TBXT 1 dataset
Motif DE_60h DE_60h-TBXT_MA0009.2 16 bp overlap
TCF4 1 dataset
ChIP GEN2-2 GSE76147.TCF4.GEN2-2 139 bp overlap
TEAD1 1 dataset
ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 138 bp overlap
TRPS1 3 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
YY1 1 dataset
ChIP RH4_DMSO-6H GSE116344.YY1.RH4_DMSO-6H 145 bp overlap
ZBTB18 3 datasets
Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_60h DE_60h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap
ZBTB24 1 dataset
Motif DE_60h DE_60h-ZBTB24_MA2330.1 10 bp overlap
ZBTB26 3 datasets
Motif DE_48h DE_48h-ZBTB26_MA1579.2 8 bp overlap
Motif DE_60h DE_60h-ZBTB26_MA1579.2 8 bp overlap
Motif DE_72h DE_72h-ZBTB26_MA1579.2 8 bp overlap
ZFP3 1 dataset
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR581GUY.ZFP3.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 55 bp overlap
ZFP42 1 dataset
Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap
ZIC1 2 datasets
Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap
Motif DE_72h DE_72h-ZIC1_MA0696.1 14 bp overlap
ZIC4 2 datasets
Motif DE_60h DE_60h-ZIC4_MA0751.2 14 bp overlap
Motif DE_72h DE_72h-ZIC4_MA0751.2 14 bp overlap
ZIC5 2 datasets
Motif DE_60h DE_60h-ZIC5_MA1584.2 15 bp overlap
Motif DE_72h DE_72h-ZIC5_MA1584.2 15 bp overlap
ZIM3 1 dataset
Motif DE_60h DE_60h-ZIM3_MA1709.2 11 bp overlap
ZKSCAN5 3 datasets
Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_72h DE_72h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF143 1 dataset
Motif DE_60h DE_60h-ZNF143_MA0088.2 16 bp overlap
ZNF148 1 dataset
Motif DE_60h DE_60h-ZNF148_MA1653.2 10 bp overlap
ZNF19 1 dataset
ChIP HEK293T GSE78099.ZNF19.HEK293T 505 bp overlap
ZNF274 2 datasets
Motif DE_48h DE_48h-ZNF274_MA1592.2 12 bp overlap
Motif DE_60h DE_60h-ZNF274_MA1592.2 12 bp overlap
ZNF281 1 dataset
Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap
ZNF558 2 datasets
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
Motif DE_60h DE_60h-ZNF558_MA2335.1 29 bp overlap
ZNF677 3 datasets
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap
Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap
ZNF740 1 dataset
Motif DE_60h DE_60h-ZNF740_MA0753.3 10 bp overlap
ZNF75A 3 datasets
Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_60h DE_60h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_72h DE_72h-ZNF75A_MA2097.1 12 bp overlap
ZNF76 1 dataset
Motif DE_60h DE_60h-ZNF76_MA1716.2 17 bp overlap
ZSCAN31 2 datasets
Motif DE_48h DE_48h-ZSCAN31_MA1722.2 18 bp overlap
Motif DE_60h DE_60h-ZSCAN31_MA1722.2 18 bp overlap
Zfp809 1 dataset
Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap
Zic1::Zic2 2 datasets
Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap
Zic2 2 datasets
Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap
Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap
Zic3 2 datasets
Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap
Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap
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