chr2 : 235,145,653 – 235,146,792
1,139 bp 76 TFs 2 linked genes
This 1.1 kb open chromatin element is linked to SH3BP4 and ENSG00000235726 and is bound by 76 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SH3BP4 194.2 kb Distal Multiome
ENSG00000235726 257.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:235,140,653 – 235,151,792
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
76 transcription factors
Source
Cell type
ASCL1 1 dataset
Motif DE_48h DE_48h-ASCL1_MA1631.2 9 bp overlap
ATOH7 3 datasets
Motif DE_48h DE_48h-ATOH7_MA1468.1 10 bp overlap
Motif DE_60h DE_60h-ATOH7_MA1468.1 10 bp overlap
Motif DE_72h DE_72h-ATOH7_MA1468.1 10 bp overlap
Ar 3 datasets
Motif DE_48h DE_48h-Ar_MA0007.4 16 bp overlap
Motif DE_60h DE_60h-Ar_MA0007.4 16 bp overlap
Motif DE_72h DE_72h-Ar_MA0007.4 16 bp overlap
Arid3a 3 datasets
Motif DE_48h DE_48h-Arid3a_MA0151.1 6 bp overlap
Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap
Motif DE_72h DE_72h-Arid3a_MA0151.1 6 bp overlap
BRD4 3 datasets
ChIP CHL-1 GSE95585.BRD4.CHL-1 122 bp overlap
ChIP MM1-S GSE43743.BRD4.MM1-S 126 bp overlap
ChIP MM1-S_JQ1_5NM GSE42355.BRD4.MM1-S_JQ1_5NM 127 bp overlap
CTCF 17 datasets
ChIP A-673 ENCSR611JJS.CTCF.A-673 166 bp overlap
ChIP MCF-10A GSE98551.CTCF.MCF-10A 88 bp overlap
ChIP MCF-7 ENCFF198DQX 129 bp overlap
ChIP MCF-7 ENCFF494VXA 129 bp overlap
ChIP MCF-7 ENCSR000DMR.CTCF.MCF-7 93 bp overlap
ChIP MCF-7 ENCSR000AHD.CTCF.MCF-7 64 bp overlap
ChIP MM.1S ENCFF869JMQ 230 bp overlap
ChIP MM1-S ENCSR402IDP.CTCF.MM1-S 168 bp overlap
ChIP chondrocyte ENCFF134ORZ 305 bp overlap
ChIP choroid plexus epithelial cell ENCFF407YNR 149 bp overlap
ChIP choroid-plexus_epithelial ENCSR000DTL.CTCF.choroid-plexus_epithelial 94 bp overlap
ChIP colon_transverse ENCSR102CSD.CTCF.colon_transverse 142 bp overlap
ChIP endodermal cell ENCFF471YCZ 83 bp overlap
ChIP endothelial_brain-microvascular ENCSR000DTA.CTCF.endothelial_brain-microvascular 71 bp overlap
ChIP lung_left_upper-lobe ENCSR972LYL.CTCF.lung_left_upper-lobe 70 bp overlap
ChIP lung_left_upper-lobe ENCSR027FSZ.CTCF.lung_left_upper-lobe 88 bp overlap
ChIP osteoblast ENCSR000APF.CTCF.osteoblast 89 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF460KDD 251 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 221 bp overlap
ESRRA 3 datasets
Motif DE_48h DE_48h-ESRRA_MA0592.4 9 bp overlap
Motif DE_60h DE_60h-ESRRA_MA0592.4 9 bp overlap
Motif DE_72h DE_72h-ESRRA_MA0592.4 9 bp overlap
Elf5 3 datasets
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
Motif DE_60h DE_60h-Elf5_MA0136.4 8 bp overlap
Motif DE_72h DE_72h-Elf5_MA0136.4 8 bp overlap
Esrrg 3 datasets
Motif DE_48h DE_48h-Esrrg_MA0643.2 9 bp overlap
Motif DE_60h DE_60h-Esrrg_MA0643.2 9 bp overlap
Motif DE_72h DE_72h-Esrrg_MA0643.2 9 bp overlap
FIGLA 1 dataset
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
FOSL2 2 datasets
Motif DE_48h DE_48h-FOSL2_MA0478.2 10 bp overlap
Motif DE_60h DE_60h-FOSL2_MA0478.2 10 bp overlap
FOXA1 1 dataset
ChIP LNCaP_F266S_shFOXA1 GSE128883.FOXA1.LNCaP_F266S_shFOXA1 64 bp overlap
FOXA2 1 dataset
ChIP DE DE-FOXA2-1 526 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 922 bp overlap
ChIP DE DE-GATA4-2 902 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 999 bp overlap
ChIP DE DE-GATA6-2 959 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 652 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 653 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 909 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 970 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 665 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 668 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 496 bp overlap
HAND2 5 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 255 bp overlap
Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap
Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap
Motif DE_72h DE_72h-HAND2_MA1638.2 6 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 163 bp overlap
HLF 1 dataset
Motif DE_72h DE_72h-HLF_MA0043.4 9 bp overlap
HNF4A 5 datasets
ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 104 bp overlap
Motif DE_48h DE_48h-HNF4A_MA1494.2 14 bp overlap
Motif DE_60h DE_60h-HNF4A_MA1494.2 14 bp overlap
Motif DE_72h DE_72h-HNF4A_MA0114.5 9 bp overlap
Motif DE_72h DE_72h-HNF4A_MA1494.2 14 bp overlap
HNF4G 1 dataset
Motif DE_72h DE_72h-HNF4G_MA0484.3 9 bp overlap
Hand1::Tcf3 3 datasets
Motif DE_48h DE_48h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_72h DE_72h-Hand1Tcf3_MA0092.2 9 bp overlap
IKZF2 3 datasets
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap
ISL1 1 dataset
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 242 bp overlap
MED1 1 dataset
ChIP MM1-S_JQ1_5NM GSE49224.MED1.MM1-S_JQ1_5NM 228 bp overlap
MYOD1 1 dataset
Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap
NEUROD1 2 datasets
ChIP D283-Med GSE92582.NEUROD1.D283-Med 446 bp overlap
ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 230 bp overlap
NFKB1 1 dataset
ChIP MCF10A-Er-Src_TAM GSE115597.NFKB1.MCF10A-Er-Src_TAM 75 bp overlap
NR2C1 3 datasets
Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap
Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap
Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap
NR2C2 3 datasets
Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap
Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap
Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap
NR2F1 6 datasets
Motif DE_48h DE_48h-NR2F1_MA0017.3 12 bp overlap
Motif DE_48h DE_48h-NR2F1_MA1537.2 13 bp overlap
Motif DE_60h DE_60h-NR2F1_MA0017.3 12 bp overlap
Motif DE_60h DE_60h-NR2F1_MA1537.2 13 bp overlap
Motif DE_72h DE_72h-NR2F1_MA0017.3 12 bp overlap
Motif DE_72h DE_72h-NR2F1_MA1537.2 13 bp overlap
NR2F2 3 datasets
Motif DE_48h DE_48h-NR2F2_MA1111.2 7 bp overlap
Motif DE_60h DE_60h-NR2F2_MA1111.2 7 bp overlap
Motif DE_72h DE_72h-NR2F2_MA1111.2 7 bp overlap
NR3C1 3 datasets
Motif DE_48h DE_48h-NR3C1_MA0113.4 15 bp overlap
Motif DE_60h DE_60h-NR3C1_MA0113.4 15 bp overlap
Motif DE_72h DE_72h-NR3C1_MA0113.4 15 bp overlap
NR3C2 3 datasets
Motif DE_48h DE_48h-NR3C2_MA0727.2 15 bp overlap
Motif DE_60h DE_60h-NR3C2_MA0727.2 15 bp overlap
Motif DE_72h DE_72h-NR3C2_MA0727.2 15 bp overlap
NR4A1 3 datasets
Motif DE_48h DE_48h-NR4A1_MA1112.3 8 bp overlap
Motif DE_60h DE_60h-NR4A1_MA1112.3 8 bp overlap
Motif DE_72h DE_72h-NR4A1_MA1112.3 8 bp overlap
NR4A2 3 datasets
Motif DE_48h DE_48h-NR4A2_MA0160.3 8 bp overlap
Motif DE_60h DE_60h-NR4A2_MA0160.3 8 bp overlap
Motif DE_72h DE_72h-NR4A2_MA0160.3 8 bp overlap
NR5A1 3 datasets
Motif DE_48h DE_48h-NR5A1_MA1540.3 12 bp overlap
Motif DE_60h DE_60h-NR5A1_MA1540.3 12 bp overlap
Motif DE_72h DE_72h-NR5A1_MA1540.3 12 bp overlap
Nr1H2 3 datasets
Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 3 datasets
Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 3 datasets
Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap
Nr2F6 3 datasets
Motif DE_48h DE_48h-Nr2F6_MA0728.1 15 bp overlap
Motif DE_60h DE_60h-Nr2F6_MA0728.1 15 bp overlap
Motif DE_72h DE_72h-Nr2F6_MA0728.1 15 bp overlap
Nr2f6 3 datasets
Motif DE_48h DE_48h-Nr2f6_MA0677.2 13 bp overlap
Motif DE_60h DE_60h-Nr2f6_MA0677.2 13 bp overlap
Motif DE_72h DE_72h-Nr2f6_MA0677.2 13 bp overlap
OTX2 1 dataset
ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 282 bp overlap
PBX1 3 datasets
Motif DE_48h DE_48h-PBX1_MA0070.2 9 bp overlap
Motif DE_60h DE_60h-PBX1_MA0070.2 9 bp overlap
Motif DE_72h DE_72h-PBX1_MA0070.2 9 bp overlap
PHOX2B 1 dataset
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 370 bp overlap
PPARA::RXRA 3 datasets
Motif DE_48h DE_48h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_60h DE_60h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_72h DE_72h-PPARARXRA_MA1148.2 17 bp overlap
Pgr 3 datasets
Motif DE_48h DE_48h-Pgr_MA2323.1 17 bp overlap
Motif DE_60h DE_60h-Pgr_MA2323.1 17 bp overlap
Motif DE_72h DE_72h-Pgr_MA2323.1 17 bp overlap
Ppara 3 datasets
Motif DE_48h DE_48h-Ppara_MA2338.1 7 bp overlap
Motif DE_60h DE_60h-Ppara_MA2338.1 7 bp overlap
Motif DE_72h DE_72h-Ppara_MA2338.1 7 bp overlap
Pparg::Rxra 3 datasets
Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_60h DE_60h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap
Ptf1A 3 datasets
Motif DE_48h DE_48h-Ptf1A_MA1618.2 9 bp overlap
Motif DE_60h DE_60h-Ptf1A_MA1618.2 9 bp overlap
Motif DE_72h DE_72h-Ptf1A_MA1618.2 9 bp overlap
RAD21 4 datasets
ChIP A-549 ENCSR000BUC.RAD21.A-549 58 bp overlap
ChIP A549 ENCFF047SFC 112 bp overlap
ChIP MCF-7 ENCSR000BTQ.RAD21.MCF-7 50 bp overlap
ChIP MCF-7 GSE72082.RAD21.MCF-7 74 bp overlap
RELA 9 datasets
ChIP Detroit-562_Pam2CSK4 GSE91018.RELA.Detroit-562_Pam2CSK4 112 bp overlap
ChIP Detroit-562_Poly-I GSE91018.RELA.Detroit-562_Poly-I 130 bp overlap
ChIP Detroit-562_TNFa GSE91018.RELA.Detroit-562_TNFa 145 bp overlap
ChIP Detroit-562_tri-DAP GSE91018.RELA.Detroit-562_tri-DAP 60 bp overlap
ChIP FaDu_LPS GSE132018.RELA.FaDu_LPS 93 bp overlap
ChIP LNCaP_DHT_TNFA GSE83860.RELA.LNCaP_DHT_TNFA 118 bp overlap
ChIP LNCaP_SICTR_TNFA GSE83860.RELA.LNCaP_SICTR_TNFA 108 bp overlap
ChIP LNCaP_SIFOXA1_TNFA GSE83860.RELA.LNCaP_SIFOXA1_TNFA 126 bp overlap
ChIP SW480_16h_TNFa GSE102796.RELA.SW480_16h_TNFa 197 bp overlap
RORA 3 datasets
Motif DE_48h DE_48h-RORA_MA0071.1 10 bp overlap
Motif DE_60h DE_60h-RORA_MA0071.1 10 bp overlap
Motif DE_72h DE_72h-RORA_MA0071.1 10 bp overlap
RXRB 3 datasets
Motif DE_48h DE_48h-RXRB_MA0855.1 14 bp overlap
Motif DE_60h DE_60h-RXRB_MA0855.1 14 bp overlap
Motif DE_72h DE_72h-RXRB_MA0855.1 14 bp overlap
RXRG 3 datasets
Motif DE_48h DE_48h-RXRG_MA0856.1 14 bp overlap
Motif DE_60h DE_60h-RXRG_MA0856.1 14 bp overlap
Motif DE_72h DE_72h-RXRG_MA0856.1 14 bp overlap
Rarb 3 datasets
Motif DE_48h DE_48h-Rarb_MA0857.1 16 bp overlap
Motif DE_60h DE_60h-Rarb_MA0857.1 16 bp overlap
Motif DE_72h DE_72h-Rarb_MA0857.1 16 bp overlap
Rarg 3 datasets
Motif DE_48h DE_48h-Rarg_MA0859.2 15 bp overlap
Motif DE_60h DE_60h-Rarg_MA0859.2 15 bp overlap
Motif DE_72h DE_72h-Rarg_MA0859.2 15 bp overlap
Rxra 3 datasets
Motif DE_48h DE_48h-Rxra_MA0512.2 14 bp overlap
Motif DE_60h DE_60h-Rxra_MA0512.2 14 bp overlap
Motif DE_72h DE_72h-Rxra_MA0512.2 14 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 550 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 456 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 341 bp overlap
SMARCA4 1 dataset
ChIP NGP GSE134626.SMARCA4.NGP 140 bp overlap
SOX10 3 datasets
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 728 bp overlap
STAG1 2 datasets
ChIP MCF-7 ERP000209.STAG1.MCF-7 84 bp overlap
ChIP MCF-7_E2 ERP000209.STAG1.MCF-7_E2 83 bp overlap
STAT3 1 dataset
ChIP A-137 GSE85579.STAT3.A-137 94 bp overlap
Sox11 3 datasets
Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap
Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap
Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap
TAL1 1 dataset
ChIP PRIMA2 GSE33850.TAL1.PRIMA2 178 bp overlap
TBX2 1 dataset
ChIP Kelly GSE94822.TBX2.Kelly 259 bp overlap
TCF4 2 datasets
Motif DE_48h DE_48h-TCF4_MA0830.3 8 bp overlap
ChIP SK-N-SH ENCFF270OWF 437 bp overlap
TCF7L1 6 datasets
Motif DE_48h DE_48h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_48h DE_48h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap
TWIST1 3 datasets
Motif DE_48h DE_48h-TWIST1_MA1123.3 8 bp overlap
Motif DE_60h DE_60h-TWIST1_MA1123.3 8 bp overlap
Motif DE_72h DE_72h-TWIST1_MA1123.3 8 bp overlap
ZBTB18 3 datasets
Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_60h DE_60h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap
ZEB1 1 dataset
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
ZNF140 3 datasets
Motif DE_48h DE_48h-ZNF140_MA1589.2 19 bp overlap
Motif DE_60h DE_60h-ZNF140_MA1589.2 19 bp overlap
Motif DE_72h DE_72h-ZNF140_MA1589.2 19 bp overlap
ZNF680 3 datasets
Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap
Motif DE_60h DE_60h-ZNF680_MA1729.2 11 bp overlap
Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap
ZNF85 3 datasets
Motif DE_48h DE_48h-ZNF85_MA1720.2 12 bp overlap
Motif DE_48h DE_48h-ZNF85_MA1720.2 12 bp overlap
Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap
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