chr2:24,191,824–24,192,305

chr2 : 24,191,824 – 24,192,305

481 bp 68 TFs 9 linked genes

This 481 bp open chromatin element is linked to 9 target genes and is bound by 68 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TP53I3		106.8 kb	Distal	Multiome
FAM228B		115.1 kb	Distal	Multiome
SF3B6		115.6 kb	Distal	Multiome
FKBP1B		142.3 kb	Distal	Multiome
WDCP		144.6 kb	Distal	Multiome
ITSN2		168.5 kb	Distal	Multiome
UBXN2A		251.5 kb	Distal	Multiome
ATAD2B		264.9 kb	Distal	Multiome
NCOA1		299.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

68 transcription factors

BCL11A 1 dataset

ChIP GM12878 ENCSR000BHA.BCL11A.GM12878 229 bp overlap

CREBBP_M768 1 dataset

ChIP NCI-H3396_E2 GSE32349.CREBBP_M768.NCI-H3396_E2 96 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 248 bp overlap

ChIP GSC23 GSE139416.CTCF.GSC23 203 bp overlap

CTNNB1 2 datasets

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 360 bp overlap

ChIP hiPSC_TT-neg_D2 GSE132532.CTNNB1.hiPSC_TT-neg_D2 361 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 393 bp overlap

ChIP BLaER1 ENCFF680YXW 286 bp overlap

ChIP GM12878 ENCSR509FWH.DPF2.GM12878 117 bp overlap

Motif DE_72h DE_72h-Dux_MA0611.3 11 bp overlap

E2F1 2 datasets

Motif DE_60h DE_60h-E2F1_MA0024.3 12 bp overlap

Motif DE_72h DE_72h-E2F1_MA0024.3 12 bp overlap

E2F2 2 datasets

Motif DE_60h DE_60h-E2F2_MA0864.3 13 bp overlap

Motif DE_72h DE_72h-E2F2_MA0864.3 13 bp overlap

E2F4 2 datasets

Motif DE_60h DE_60h-E2F4_MA0470.3 13 bp overlap

Motif DE_72h DE_72h-E2F4_MA0470.3 13 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 315 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 131 bp overlap

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 265 bp overlap

FEZF2 2 datasets

Motif DE_60h DE_60h-FEZF2_MA2341.1 8 bp overlap

Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 424 bp overlap

ChIP DE DE-FOXA2-2 419 bp overlap

GATA1 2 datasets

ChIP K-562 GSE107726.GATA1.K-562 192 bp overlap

ChIP K562 ENCFF094CMK 231 bp overlap

GATA2 2 datasets

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

ChIP hiPSC_SLC9ebs GSE107639.GATA2.hiPSC_SLC9ebs 295 bp overlap

GATA4 6 datasets

ChIP DE DE-GATA4-1 479 bp overlap

ChIP DE DE-GATA4-2 481 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 368 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 314 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 305 bp overlap

GATA5 1 dataset

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 15 datasets

ChIP DE DE-GATA6-1 443 bp overlap

ChIP DE DE-GATA6-2 481 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 481 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 481 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 481 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 481 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 481 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 481 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 348 bp overlap

ChIP foregut GSE117136.GATA6.foregut 318 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 445 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 314 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 324 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 301 bp overlap

Motif DE_72h DE_72h-GFI1_MA0038.3 11 bp overlap

GFI1B 1 dataset

ChIP SET-2_GSK GSE121424.GFI1B.SET-2_GSK 162 bp overlap

Gata3 1 dataset

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

Gfi1B 1 dataset

Motif DE_72h DE_72h-Gfi1B_MA0483.2 10 bp overlap

HAND2 2 datasets

Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap

Motif DE_72h DE_72h-HAND2_MA1638.2 6 bp overlap

IKZF1 2 datasets

ChIP GM12878 ENCFF753XDO 357 bp overlap

ChIP GM12878 ENCFF824TGK 266 bp overlap

IKZF2 4 datasets

ChIP GM12878 ENCFF238LYK 481 bp overlap

ChIP GM12878 ENCFF918AID 457 bp overlap

ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 350 bp overlap

ChIP GM12878 ENCSR822AHX.IKZF2.GM12878 306 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 311 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 465 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 395 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 437 bp overlap

KMT2B-D 1 dataset

ChIP SW480 GSE115985.KMT2B-D.SW480 408 bp overlap

LEF1 2 datasets

ChIP K-562 ENCSR343ELW.LEF1.K-562 318 bp overlap

ChIP K562 ENCFF198WCP 440 bp overlap

MEIS1 1 dataset

Motif DE_72h DE_72h-MEIS1_MA1639.2 9 bp overlap

MEIS2 1 dataset

Motif DE_72h DE_72h-MEIS2_MA1640.2 9 bp overlap

MGA::EVX1 1 dataset

Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap

MTA2 2 datasets

ChIP GM12878 ENCFF615CWQ 477 bp overlap

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 471 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 226 bp overlap

Motif DE_72h DE_72h-Mafg_MA0659.4 12 bp overlap

NFATC3 1 dataset

ChIP GM12878 ENCSR437GBJ.NFATC3.GM12878 252 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 274 bp overlap

Motif DE_72h DE_72h-PBX2_MA1113.3 9 bp overlap

PLAG1 1 dataset

Motif DE_72h DE_72h-PLAG1_MA0163.1 14 bp overlap

ChIP GM12878 ENCSR387QUV.RELB.GM12878 326 bp overlap

RUNX3 1 dataset

Motif DE_72h DE_72h-RUNX3_MA0684.3 8 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 155 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 481 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 481 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 481 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 481 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 481 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 481 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 388 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 414 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 206 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S10-DE-d1-BAF155-exp1 311 bp overlap

ChIP DE_D1 S15-DE-d1-BAF155-exp1 272 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 378 bp overlap

Stat2 1 dataset

Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 187 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 410 bp overlap

TARDBP 1 dataset

ChIP GM12878 ENCSR412QBS.TARDBP.GM12878 308 bp overlap

Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap

Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap

Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap

TCF12 1 dataset

ChIP GM12878 ENCSR000BGZ.TCF12.GM12878 103 bp overlap

TRPS1 1 dataset

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap

ZBTB33 1 dataset

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 253 bp overlap

ZBTB6 1 dataset

Motif DE_72h DE_72h-ZBTB6_MA1581.2 9 bp overlap

Motif DE_72h DE_72h-ZIM3_MA1709.2 11 bp overlap

ZNF331 1 dataset

Motif DE_72h DE_72h-ZNF331_MA1726.2 10 bp overlap

ZNF410 2 datasets

Motif DE_60h DE_60h-ZNF410_MA0752.2 16 bp overlap

Motif DE_72h DE_72h-ZNF410_MA0752.2 16 bp overlap

ZNF574 2 datasets

Motif DE_60h DE_60h-ZNF574_MA1982.2 14 bp overlap

Motif DE_72h DE_72h-ZNF574_MA1982.2 14 bp overlap

ZNF667 1 dataset

Motif DE_72h DE_72h-ZNF667_MA1984.2 11 bp overlap

ZNF76 1 dataset

Motif DE_72h DE_72h-ZNF76_MA1716.2 17 bp overlap