chr17:7,971,685–7,972,375

chr17 : 7,971,685 – 7,972,375

690 bp 45 TFs 14 linked genes

This 690 bp open chromatin element is linked to 14 target genes and is bound by 45 transcription factors.

Linked Genes

14 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CNTROB		39.8 kb	Distal	Multiome
TRAPPC1		40.0 kb	Distal	Multiome
CHD3		87.1 kb	Distal	Multiome
NAA38		114.4 kb	Distal	Multiome
KDM6B		127.0 kb	Distal	Multiome
PER1		184.4 kb	Distal	Multiome
VAMP2		191.0 kb	Distal	Multiome
TMEM107		204.5 kb	Distal	Multiome
AURKB		238.7 kb	Distal	Multiome
EFNB3		266.7 kb	Distal	Multiome
CTC1		276.1 kb	Distal	Multiome
PFAS		277.4 kb	Distal	Multiome
WRAP53		283.5 kb	Distal	Multiome
TP53		284.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

45 transcription factors

ChIP MCF-7 GSE48930.AR.MCF-7 178 bp overlap

BCL11A 1 dataset

ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 53 bp overlap

BCL6 2 datasets

ChIP HepG2 ENCFF423EJH 187 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 210 bp overlap

ChIP B-cell_GERMINAL_CENTER GSE43350.BCOR.B-cell_GERMINAL_CENTER 149 bp overlap

ChIP H-1_DE GSE126661.BRD3.H-1_DE 397 bp overlap

ChIP K-562 ENCSR000ATW.CBX8.K-562 391 bp overlap

CTCF 131 datasets

ChIP 22Rv1 ENCFF466OXN 117 bp overlap

ChIP 22Rv1_hydroxy_10nM_4h ENCSR847XGE.CTCF.22Rv1_hydroxy_10nM_4h 154 bp overlap

ChIP 786-O_NORMOXIA GSE78113.CTCF.786-O_NORMOXIA 263 bp overlap

ChIP A-549 ENCSR000AUE.CTCF.A-549 263 bp overlap

ChIP A-549 ENCSR000AUF.CTCF.A-549 229 bp overlap

ChIP A-549 ENCSR000DPF.CTCF.A-549 206 bp overlap

ChIP A-673 ENCSR611JJS.CTCF.A-673 170 bp overlap

ChIP A549 ENCFF034FVO 278 bp overlap

ChIP ASC GSE21366.CTCF.ASC 171 bp overlap

ChIP B cell ENCFF500PZO 73 bp overlap

ChIP BJ ENCSR000DQI.CTCF.BJ 215 bp overlap

ChIP C4-2B ENCFF821XVN 76 bp overlap

ChIP CD14-positive monocyte ENCFF087XLR 193 bp overlap

ChIP DOHH2 ENCSR084RDK.CTCF.DOHH2 259 bp overlap

ChIP GM04025_B-lymphocytes GSE111170.CTCF.GM04025_B-lymphocytes 149 bp overlap

ChIP GM04604 GSE148179.CTCF.GM04604 217 bp overlap

ChIP GM04648 GSE148179.CTCF.GM04648 156 bp overlap

ChIP GM09236__B-lymphocytes GSE111170.CTCF.GM09236__B-lymphocytes 91 bp overlap

ChIP GM09237_B-lymphocytes GSE111170.CTCF.GM09237_B-lymphocytes 150 bp overlap

ChIP GM12866 ENCSR000DRF.CTCF.GM12866 141 bp overlap

ChIP GM12867 ENCSR000DRH.CTCF.GM12867 101 bp overlap

ChIP GM12872 ENCSR000DRN.CTCF.GM12872 122 bp overlap

ChIP GM23338 ENCFF832KWE 75 bp overlap

ChIP GP5D GSE51234.CTCF.GP5D 333 bp overlap

ChIP GP5D_SIRAD21 GSE51234.CTCF.GP5D_SIRAD21 91 bp overlap

ChIP HAP1 GSE152721.CTCF.HAP1 97 bp overlap

ChIP HAP1_WT GSE126634.CTCF.HAP1_WT 94 bp overlap

ChIP HAP1_clone21_CTCF-TSS-CRISPR_1 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_1 92 bp overlap

ChIP HAP1_clone21_CTCF-TSS-CRISPR_2 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_2 62 bp overlap

ChIP HAP1_clone21_TSS-CRISPR GSE152721.CTCF.HAP1_clone21_TSS-CRISPR 118 bp overlap

ChIP HCT-116 GSE131606.CTCF.HCT-116 601 bp overlap

ChIP HCT-116 ENCSR240PRQ.CTCF.HCT-116 218 bp overlap

ChIP HCT-116 ENCSR000DTO.CTCF.HCT-116 160 bp overlap

ChIP HCT-116_RAD21-mAC GSE104888.CTCF.HCT-116_RAD21-mAC 178 bp overlap

ChIP HCT-116_RAD21-mAC_500uM_auxin GSE104888.CTCF.HCT-116_RAD21-mAC_500uM_auxin 162 bp overlap

ChIP HCT116 ENCFF209YMI 229 bp overlap

ChIP HEK293 ENCSR000DTW.CTCF.HEK293 106 bp overlap

ChIP HT-1080 GSE135580.CTCF.HT-1080 385 bp overlap

ChIP HT-1080_CBL0137-6h GSE122462.CTCF.HT-1080_CBL0137-6h 207 bp overlap

ChIP HUDEP-2_30min GSE104676.CTCF.HUDEP-2_30min 66 bp overlap

ChIP HeLa GSE126990.CTCF.HeLa 127 bp overlap

ChIP HeLa-Kyoto GSE138405.CTCF.HeLa-Kyoto 127 bp overlap

ChIP HeLa-Kyoto_PDS5-depleted GSE102884.CTCF.HeLa-Kyoto_PDS5-depleted 176 bp overlap

ChIP HeLa-Kyoto_WAPL_PDS-depleted GSE102884.CTCF.HeLa-Kyoto_WAPL_PDS-depleted 128 bp overlap

ChIP HeLa-S3 ENCFF565UFR 141 bp overlap

ChIP HeLa-S3 ENCSR000AOA.CTCF.HeLa-S3 339 bp overlap

ChIP HeLa-S3 ENCSR000DUB.CTCF.HeLa-S3 153 bp overlap

ChIP HeLa-S3 ENCSR000DLO.CTCF.HeLa-S3 88 bp overlap

ChIP HeLa-S3_biotin GSE108869.CTCF.HeLa-S3_biotin 154 bp overlap

ChIP HeLa-S3_shCtrl GSE137848.CTCF.HeLa-S3_shCtrl 191 bp overlap

ChIP HeLa-S3_unsynchro GSE108173.CTCF.HeLa-S3_unsynchro 192 bp overlap

ChIP HeLa_dC9Sun-D3A_MIR152 GSE107607.CTCF.HeLa_dC9Sun-D3A_MIR152 178 bp overlap

ChIP HeLa_dC9Sun-D3A_SHB GSE107607.CTCF.HeLa_dC9Sun-D3A_SHB 202 bp overlap

ChIP Hep-G2 ERP000209.CTCF.Hep-G2 119 bp overlap

ChIP Hep-G2 ENCSR000BIE.CTCF.Hep-G2 92 bp overlap

ChIP K-562_8005 GSE131349.CTCF.K-562_8005 89 bp overlap

ChIP K-562_MonoC GSE137216.CTCF.K-562_MonoC 223 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.CTCF.K-562_dCas9-KRAB 200 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.CTCF.K-562_dCas9-LSD1 127 bp overlap

ChIP KARPAS422 ENCSR113REG.CTCF.KARPAS422 100 bp overlap

ChIP LNCAP ENCFF223HIG 88 bp overlap

ChIP LNCAP ENCFF700QXT 87 bp overlap

ChIP LNCaP-C4-2B ENCSR460LGH.CTCF.LNCaP-C4-2B 234 bp overlap

ChIP Loucy ENCSR464DKE.CTCF.Loucy 300 bp overlap

ChIP MCF-10A GSE98551.CTCF.MCF-10A 220 bp overlap

ChIP MCF-10AT1 GSE98551.CTCF.MCF-10AT1 79 bp overlap

ChIP MCF-7 ENCSR000DMR.CTCF.MCF-7 158 bp overlap

ChIP MCF-7 ENCSR000DMS.CTCF.MCF-7 132 bp overlap

ChIP MCF-7 ENCSR560BUE.CTCF.MCF-7 137 bp overlap

ChIP MCF-7L_t1 GSE108787.CTCF.MCF-7L_t1 183 bp overlap

ChIP MCF-7L_t24 GSE108787.CTCF.MCF-7L_t24 132 bp overlap

ChIP MCF-7L_t4 GSE108787.CTCF.MCF-7L_t4 109 bp overlap

ChIP OCI-LY1 ENCFF455ESK 50 bp overlap

ChIP OCI-Ly1 ENCSR072EUE.CTCF.OCI-Ly1 198 bp overlap

ChIP OCI-Ly7 ENCSR027HML.CTCF.OCI-Ly7 171 bp overlap

ChIP OVCAR-8 GSE70764.CTCF.OVCAR-8 123 bp overlap

ChIP PC-3 ENCSR359LOD.CTCF.PC-3 221 bp overlap

ChIP RWPE-1 ENCSR303GFI.CTCF.RWPE-1 54 bp overlap

ChIP RWPE-2 ENCSR856JJB.CTCF.RWPE-2 82 bp overlap

ChIP RWPE1 ENCFF200GQF 196 bp overlap

ChIP SK-N-SH ENCSR541AMF.CTCF.SK-N-SH 245 bp overlap

ChIP SK-N-SH ENCSR000DXQ.CTCF.SK-N-SH 170 bp overlap

ChIP SLK_Ctrl GSE138105.CTCF.SLK_Ctrl 62 bp overlap

ChIP T-47D GSE111923.CTCF.T-47D 134 bp overlap

ChIP VCaP ENCFF858YQT 139 bp overlap

ChIP WA01 ENCSR000DLK.CTCF.WA01 199 bp overlap

ChIP WA01_MESEN_STEM GSE52457.CTCF.WA01_MESEN_STEM 189 bp overlap

ChIP WI-38 ENCSR000DYB.CTCF.WI-38 158 bp overlap

ChIP activated CD8-positive, alpha-beta T cell ENCFF006MHW 65 bp overlap

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 310 bp overlap

ChIP astrocyte_spinal_cord ENCSR000DSU.CTCF.astrocyte_spinal_cord 111 bp overlap

ChIP cardiac_muscle ENCSR000DTI.CTCF.cardiac_muscle 145 bp overlap

ChIP chondrocyte ENCFF134ORZ 58 bp overlap

ChIP choroid-plexus_epithelial ENCSR000DTL.CTCF.choroid-plexus_epithelial 126 bp overlap

ChIP cortical-interneuron_KCl-neg_JQ1-neg GSE117508.CTCF.cortical-interneuron_KCl-neg_JQ1-neg 84 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF257LSY 57 bp overlap

ChIP endothelial_brain-microvascular ENCSR000DTA.CTCF.endothelial_brain-microvascular 170 bp overlap

ChIP epithelial_retinal_pigment ENCSR000DVI.CTCF.epithelial_retinal_pigment 152 bp overlap

ChIP erythroblast_adult_erythroblasts GSE102184.CTCF.erythroblast_adult_erythroblasts 180 bp overlap

ChIP erythroid GSE67783.CTCF.erythroid 162 bp overlap

ChIP esophagus_squamous-epithelium ENCSR450FRI.CTCF.esophagus_squamous-epithelium 73 bp overlap

ChIP fetal_erythroblasts GSE102184.CTCF.fetal_erythroblasts 128 bp overlap

ChIP fibroblast_AORTIC_ADVENTITIA ENCSR000DPY.CTCF.fibroblast_AORTIC_ADVENTITIA 203 bp overlap

ChIP fibroblast_LUNG ENCSR000ANO.CTCF.fibroblast_LUNG 165 bp overlap

ChIP fibroblast_PULMONARY_ARTERY ENCSR000DUX.CTCF.fibroblast_PULMONARY_ARTERY 128 bp overlap

ChIP fibroblast_VILLOUS_MESENCHYME ENCSR000DVQ.CTCF.fibroblast_VILLOUS_MESENCHYME 122 bp overlap

ChIP gastrocnemius medialis ENCFF071DIF 70 bp overlap

ChIP gastrocnemius medialis ENCFF307PRR 205 bp overlap

ChIP gastrocnemius medialis ENCFF468QWC 163 bp overlap

ChIP gastrocnemius-medialis ENCSR355ALW.CTCF.gastrocnemius-medialis 250 bp overlap

ChIP gastrocnemius-medialis ENCSR594NSU.CTCF.gastrocnemius-medialis 226 bp overlap

ChIP gastrocnemius-medialis ENCSR428BKN.CTCF.gastrocnemius-medialis 182 bp overlap

ChIP glutamatergic neuron ENCFF816BTR 147 bp overlap

ChIP hESC_D5 GSE116862.CTCF.hESC_D5 204 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 138 bp overlap

ChIP heart ENCSR232OFD.CTCF.heart 145 bp overlap

ChIP heart left ventricle ENCFF354HOQ 76 bp overlap

ChIP keratinocyte GSE154221.CTCF.keratinocyte 690 bp overlap

ChIP keratinocyte ENCSR000ALJ.CTCF.keratinocyte 203 bp overlap

ChIP keratinocyte ENCSR000DWX.CTCF.keratinocyte 88 bp overlap

ChIP left ventricle myocardium inferior ENCFF161DPW 67 bp overlap

ChIP leukemia_CEBPA-24h GSE142161.CTCF.leukemia_CEBPA-24h 152 bp overlap

ChIP leukemia_CEBPA-96h GSE142161.CTCF.leukemia_CEBPA-96h 87 bp overlap

ChIP lymphoblast_mut GSE155324.CTCF.lymphoblast_mut 197 bp overlap

ChIP myotube ENCSR000ANS.CTCF.myotube 92 bp overlap

ChIP neural ENCSR822CEA.CTCF.neural 85 bp overlap

ChIP neural progenitor cell ENCFF581WPG 104 bp overlap

ChIP osteoblast ENCSR000APF.CTCF.osteoblast 136 bp overlap

ChIP primary-glioblastoma_G583 GSE121601.CTCF.primary-glioblastoma_G583 132 bp overlap

ChIP prostate_epithelial ENCSR196HOM.CTCF.prostate_epithelial 253 bp overlap

ChIP testis ENCSR753RME.CTCF.testis 75 bp overlap

ChIP ASC GSE54889.EBF1.ASC 112 bp overlap

ChIP ProEs GSE59087.EED.ProEs 173 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 267 bp overlap

ESR1 2 datasets

ChIP MCF-7_IL1b_45m GSE67295.ESR1.MCF-7_IL1b_45m 160 bp overlap

ChIP MCF-7_Veh GSE67295.ESR1.MCF-7_Veh 214 bp overlap

EZH2 3 datasets

ChIP ProEs_SHCTR GSE59087.EZH2.ProEs_SHCTR 336 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 68 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 66 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 368 bp overlap

ChIP DE DE-FOXA2-2 308 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 448 bp overlap

ChIP DE DE-GATA4-2 504 bp overlap

GATA6 10 datasets

ChIP AGS GSE51936.GATA6.AGS 78 bp overlap

ChIP DE DE-GATA6-1 423 bp overlap

ChIP DE DE-GATA6-2 489 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 385 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 362 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 422 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 344 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 436 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 509 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 405 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 222 bp overlap

IRF2BP2 1 dataset

ChIP HEK293 GSE124636.IRF2BP2.HEK293 76 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 293 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 421 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 215 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 331 bp overlap

KDM4C 1 dataset

ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 253 bp overlap

ChIP HEK293 GSE76494.MAZ.HEK293 164 bp overlap

MECOM 1 dataset

ChIP SKH1_E2 GSE102697.MECOM.SKH1_E2 171 bp overlap

MED1 3 datasets

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 380 bp overlap

ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 223 bp overlap

ChIP hMSC-TERT4_D7 GSE104537.MED1.hMSC-TERT4_D7 66 bp overlap

ChIP P493-6_MST-312 GSE77061.MYC.P493-6_MST-312 185 bp overlap

ONECUT2 1 dataset

ChIP PC-3_normoxia GSE106305.ONECUT2.PC-3_normoxia 177 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 218 bp overlap

PDX1 3 datasets

ChIP hESC GSE58685.PDX1.hESC 135 bp overlap

ChIP hiPSC GSE125768.PDX1.hiPSC 360 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 364 bp overlap

POU5F1 1 dataset

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 99 bp overlap

PPARG 2 datasets

ChIP ASC GSE21366.PPARG.ASC 185 bp overlap

ChIP SGBS GSE41629.PPARG.SGBS 136 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 226 bp overlap

ChIP SGBS_TNF GSE64233.RELA.SGBS_TNF 66 bp overlap

ChIP Hep-G2 ENCSR000BHU.RXRA.Hep-G2 111 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 202 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 553 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 515 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 508 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 416 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 404 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 409 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 478 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 452 bp overlap

SMAD4 2 datasets

ChIP HepG2 ENCFF615GTE 229 bp overlap

ChIP endoderm GSE29422.SMAD4.endoderm 197 bp overlap

SMARCA4 1 dataset

ChIP A-549_AG15689 GSE132290.SMARCA4.A-549_AG15689 215 bp overlap

SMARCB1 1 dataset

ChIP proliferating-human-fibroblast_ASO_Ctrl GSE131711.SMARCB1.proliferating-human-fibroblast_ASO_Ctrl 400 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 172 bp overlap

SMC3 3 datasets

ChIP HeLa GSE126990.SMC3.HeLa 196 bp overlap

ChIP HeLa-Kyoto GSE102884.SMC3.HeLa-Kyoto 196 bp overlap

ChIP HeLa-Kyoto GSE138405.SMC3.HeLa-Kyoto 196 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 494 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 613 bp overlap

STAG1 2 datasets

ChIP HeLa GSE126990.STAG1.HeLa 156 bp overlap

ChIP HeLa-Kyoto GSE138405.STAG1.HeLa-Kyoto 156 bp overlap

TEAD1 1 dataset

ChIP adipocyte GSE140782.TEAD1.adipocyte 202 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 199 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 227 bp overlap