chr9:94,250,394–94,250,997

chr9 : 94,250,394 – 94,250,997

603 bp 81 TFs 7 linked genes

This 603 bp open chromatin element is linked to 7 target genes and is bound by 81 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LINC02603		8.3 kb	Proximal	Proximity
ZNF169		8.3 kb	Proximal	Proximity
MIRLET7A1HG		74.4 kb	Distal	Multiome
ENSG00000232063		81.6 kb	Distal	Multiome
MFSD14B		123.8 kb	Distal	Multiome
PTPDC1		220.0 kb	Distal	Multiome
BARX1		295.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

81 transcription factors

ChIP MCF-7_TCDD_45min GSE90550.AHR.MCF-7_TCDD_45min 183 bp overlap

ChIP MCF-7 ERP001226.AR.MCF-7 148 bp overlap

ARID1A 1 dataset

ChIP 12Z GSE129781.ARID1A.12Z 312 bp overlap

ARNT 2 datasets

ChIP MCF-7_aza GSE85352.ARNT.MCF-7_aza 359 bp overlap

ChIP SK-MEL-28 GSE85352.ARNT.SK-MEL-28 286 bp overlap

ATF4 3 datasets

ChIP Jurkat_ZBTB1-KO_Asp-deprivation GSE145783.ATF4.Jurkat_ZBTB1-KO_Asp-deprivation 245 bp overlap

ChIP K-562 ENCSR145TSJ.ATF4.K-562 250 bp overlap

ChIP K562 ENCFF674KTF 291 bp overlap

BRD4 3 datasets

ChIP CHL-1_BAY123897 GSE95585.BRD4.CHL-1_BAY123897 269 bp overlap

ChIP KOPT-K1_E GSE54379.BRD4.KOPT-K1_E 486 bp overlap

ChIP SUM159PT_30nMbortezomib_8h GSE87418.BRD4.SUM159PT_30nMbortezomib_8h 281 bp overlap

CREB1 6 datasets

ChIP Hep-G2 ENCSR112ALD.CREB1.Hep-G2 282 bp overlap

ChIP HepG2 ENCFF792THT 373 bp overlap

ChIP MCF-7 ENCFF341ZEM 295 bp overlap

ChIP MCF-7 ENCFF867SAS 295 bp overlap

ChIP MCF-7 ENCSR897JAS.CREB1.MCF-7 375 bp overlap

ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 351 bp overlap

CTBP1 2 datasets

ChIP MCF-7 ENCFF969VBY 388 bp overlap

ChIP MCF-7 ENCSR636EYA.CTBP1.MCF-7 223 bp overlap

CTCF 2 datasets

Motif DE_24h DE_24h-CTCF_MA1929.2 31 bp overlap

Motif DE_36h DE_36h-CTCF_MA1929.2 31 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 184 bp overlap

ChIP hESC GSE26097.EOMES.hESC 223 bp overlap

ERF::FIGLA 2 datasets

Motif DE_24h DE_24h-ERFFIGLA_MA1934.2 13 bp overlap

Motif DE_36h DE_36h-ERFFIGLA_MA1934.2 13 bp overlap

ChIP Jurkat GSE49091.ERG.Jurkat 124 bp overlap

ESR1 7 datasets

ChIP MCF-7 GSE41561.ESR1.MCF-7 148 bp overlap

ChIP MCF-7 ERP000209.ESR1.MCF-7 124 bp overlap

ChIP MCF-7_E2 GSE102410.ESR1.MCF-7_E2 169 bp overlap

ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 298 bp overlap

ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 298 bp overlap

ChIP MCF-7_shFbxo_E2_SRC-3 GSE119702.ESR1.MCF-7_shFbxo_E2_SRC-3 157 bp overlap

ChIP MCF-7_shFbxo_SRC-3 GSE119702.ESR1.MCF-7_shFbxo_SRC-3 157 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.ETS1.CTV-1_DSG_SPI1-mut 222 bp overlap

ChIP MCF-7 ENCSR569XNP.FOS.MCF-7 357 bp overlap

FOS::JUN 1 dataset

Motif DE_24h DE_24h-FOSJUN_MA1126.2 10 bp overlap

FOXA1 2 datasets

ChIP MCF-7 ERP001226.FOXA1.MCF-7 158 bp overlap

ChIP MCF-7_JC4693 GSE126004.FOXA1.MCF-7_JC4693 267 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 489 bp overlap

ChIP DE DE-FOXA2-2 443 bp overlap

GATA2 1 dataset

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 187 bp overlap

GATA3 3 datasets

ChIP Jurkat GSE76181.GATA3.Jurkat 326 bp overlap

ChIP MCF-7 ENCFF352QVM 195 bp overlap

ChIP MCF-7 ENCFF437NQS 371 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 520 bp overlap

ChIP DE DE-GATA4-2 603 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 582 bp overlap

ChIP DE DE-GATA6-2 584 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 603 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 603 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 603 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 494 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 603 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 603 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 446 bp overlap

ChIP foregut GSE117136.GATA6.foregut 333 bp overlap

HDAC1 1 dataset

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.HDAC1.MCF-7_parental_4-hydroxytamoxifen 213 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 193 bp overlap

HIF1A 2 datasets

ChIP PC-3_hypoxia_siCtrl GSE106305.HIF1A.PC-3_hypoxia_siCtrl 222 bp overlap

ChIP PC-3_hypoxia_siSMAD3 GSE106305.HIF1A.PC-3_hypoxia_siSMAD3 207 bp overlap

Hmga1 2 datasets

Motif DE_24h DE_24h-Hmga1_MA2124.1 8 bp overlap

Motif DE_36h DE_36h-Hmga1_MA2124.1 8 bp overlap

Hnf1A 1 dataset

Motif DE_24h DE_24h-Hnf1A_MA1991.2 10 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 243 bp overlap

Motif DE_24h DE_24h-JUN_MA0488.2 10 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 562 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 427 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 585 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 273 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 578 bp overlap

ChIP MCF-7_abemaciclib GSE157385.JUN.MCF-7_abemaciclib 276 bp overlap

Motif DE_24h DE_24h-JUND_MA0492.2 11 bp overlap

KMT2A 1 dataset

ChIP CCRF-CEM GSE83671.KMT2A.CCRF-CEM 188 bp overlap

ChIP Jurkat GSE94391.LMO1.Jurkat 311 bp overlap

Lef1 4 datasets

Motif DE_24h DE_24h-Lef1_MA0768.3 8 bp overlap

Motif DE_24h DE_24h-Lef1_MA0768.3 8 bp overlap

Motif DE_36h DE_36h-Lef1_MA0768.3 8 bp overlap

Motif DE_36h DE_36h-Lef1_MA0768.3 8 bp overlap

MAF::NFE2 2 datasets

Motif DE_24h DE_24h-MAFNFE2_MA0501.2 11 bp overlap

Motif DE_36h DE_36h-MAFNFE2_MA0501.2 11 bp overlap

ChIP 501-mel GSE61965.MITF.501-mel 231 bp overlap

Msgn1 2 datasets

Motif DE_24h DE_24h-Msgn1_MA1524.3 10 bp overlap

Motif DE_36h DE_36h-Msgn1_MA1524.3 10 bp overlap

Nfe2l2 2 datasets

Motif DE_24h DE_24h-Nfe2l2_MA0150.3 11 bp overlap

Motif DE_36h DE_36h-Nfe2l2_MA0150.3 11 bp overlap

Motif DE_24h DE_24h-PAX6_MA0069.1 14 bp overlap

PHOX2B 2 datasets

Motif DE_24h DE_24h-PHOX2B_MA0681.3 12 bp overlap

Motif DE_36h DE_36h-PHOX2B_MA0681.3 12 bp overlap

PKNOX1 2 datasets

Motif DE_24h DE_24h-PKNOX1_MA0782.3 10 bp overlap

Motif DE_36h DE_36h-PKNOX1_MA0782.3 10 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 403 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 282 bp overlap

Prdm5 1 dataset

Motif DE_24h DE_24h-Prdm5_MA1999.2 11 bp overlap

ChIP MCF-7 ENCSR066TET.RFX1.MCF-7 251 bp overlap

RUNX1 2 datasets

ChIP Jurkat GSE76181.RUNX1.Jurkat 276 bp overlap

ChIP Jurkat GSE68976.RUNX1.Jurkat 222 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 156 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 585 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 603 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 590 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 600 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 603 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 603 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 603 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 529 bp overlap

SMAD3 1 dataset

ChIP PC-3_hypoxia GSE106305.SMAD3.PC-3_hypoxia 172 bp overlap

SMAD3-HIF1A 1 dataset

ChIP PC-3_hypoxia GSE106305.SMAD3-HIF1A.PC-3_hypoxia 174 bp overlap

SMARCA4 3 datasets

ChIP CTV-1_DSG_SPI1-mut GSE128835.SMARCA4.CTV-1_DSG_SPI1-mut 217 bp overlap

ChIP CTV-1_FLAG_SPI1-mut GSE128835.SMARCA4.CTV-1_FLAG_SPI1-mut 184 bp overlap

ChIP CTV-1_delA GSE128835.SMARCA4.CTV-1_delA 210 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 530 bp overlap

SOX14 2 datasets

Motif DE_24h DE_24h-SOX14_MA1562.2 9 bp overlap

Motif DE_36h DE_36h-SOX14_MA1562.2 9 bp overlap

SOX15 2 datasets

Motif DE_24h DE_24h-SOX15_MA1152.2 7 bp overlap

Motif DE_36h DE_36h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 390 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 599 bp overlap

SOX18 2 datasets

Motif DE_24h DE_24h-SOX18_MA1563.2 8 bp overlap

Motif DE_36h DE_36h-SOX18_MA1563.2 8 bp overlap

SOX8 2 datasets

Motif DE_24h DE_24h-SOX8_MA0868.3 7 bp overlap

Motif DE_36h DE_36h-SOX8_MA0868.3 7 bp overlap

SOX9 2 datasets

Motif DE_24h DE_24h-SOX9_MA0077.2 8 bp overlap

Motif DE_36h DE_36h-SOX9_MA0077.2 8 bp overlap

STAT5B 1 dataset

ChIP CD8_H9 GSE64713.STAT5B.CD8_H9 286 bp overlap

Sox17 2 datasets

Motif DE_24h DE_24h-Sox17_MA0078.3 10 bp overlap

Motif DE_36h DE_36h-Sox17_MA0078.3 10 bp overlap

Sox5 2 datasets

Motif DE_24h DE_24h-Sox5_MA0087.3 8 bp overlap

Motif DE_36h DE_36h-Sox5_MA0087.3 8 bp overlap

Sox7 2 datasets

Motif DE_24h DE_24h-Sox7_MA2095.1 10 bp overlap

Motif DE_36h DE_36h-Sox7_MA2095.1 10 bp overlap

Stat2 1 dataset

Motif DE_24h DE_24h-Stat2_MA1623.2 10 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 392 bp overlap

TCF7 2 datasets

Motif DE_24h DE_24h-TCF7_MA0769.3 7 bp overlap

Motif DE_36h DE_36h-TCF7_MA0769.3 7 bp overlap

TCF7L1 2 datasets

Motif DE_24h DE_24h-TCF7L1_MA1421.1 12 bp overlap

Motif DE_36h DE_36h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 2 datasets

Motif DE_24h DE_24h-TCF7L2_MA0523.2 9 bp overlap

Motif DE_36h DE_36h-TCF7L2_MA0523.2 9 bp overlap

TFAP2C 2 datasets

ChIP MCF-7_E2 GSE23852.TFAP2C.MCF-7_E2 261 bp overlap

ChIP MCF-7_ETOH GSE23852.TFAP2C.MCF-7_ETOH 231 bp overlap

THAP1 2 datasets

Motif DE_24h DE_24h-THAP1_MA0597.3 8 bp overlap

Motif DE_36h DE_36h-THAP1_MA0597.3 8 bp overlap

ChIP LX2_CALCIPOTRIOL_TGFB1 GSE38103.VDR.LX2_CALCIPOTRIOL_TGFB1 181 bp overlap

Motif DE_24h DE_24h-Vdr_MA0693.4 7 bp overlap

ZNF143 1 dataset

ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 149 bp overlap

ZNF316 2 datasets

ChIP K-562 ENCSR200JYP.ZNF316.K-562 236 bp overlap

ChIP K562 ENCFF281INV 237 bp overlap

ZNF454 2 datasets

Motif DE_24h DE_24h-ZNF454_MA1712.2 17 bp overlap

Motif DE_36h DE_36h-ZNF454_MA1712.2 17 bp overlap

ZNF513 2 datasets

ChIP HEK293 ENCFF457TCC 405 bp overlap

ChIP HEK293 ENCSR503DPC.ZNF513.HEK293 245 bp overlap

ZNF701 1 dataset

Motif DE_24h DE_24h-ZNF701_MA1987.2 17 bp overlap

ZNF85 1 dataset

Motif DE_36h DE_36h-ZNF85_MA1720.2 12 bp overlap

Zic1::Zic2 1 dataset

Motif DE_36h DE_36h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_36h DE_36h-Zic2_MA1629.2 9 bp overlap

Motif DE_36h DE_36h-Zic3_MA0697.3 7 bp overlap