chr8 : 5,669,720 – 5,670,425

705 bp 90 TFs 1 linked gene

This 705 bp open chromatin element is linked to ENSG00000254007 and is bound by 90 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000254007		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

90 transcription factors

AR 8 datasets

ChIP LNCaP_DHT GSE125245.AR.LNCaP_DHT 227 bp overlap

ChIP LNCaP_DHTTHZ1 GSE125245.AR.LNCaP_DHTTHZ1 54 bp overlap

ChIP LNCaP_sgCHD1 GSE117430.AR.LNCaP_sgCHD1 247 bp overlap

ChIP LNCaP_sgCtrl GSE117430.AR.LNCaP_sgCtrl 245 bp overlap

ChIP VCaP_DHAT_18H GSE28950.AR.VCaP_DHAT_18H 120 bp overlap

ChIP VCaP_DHAT_2H GSE28950.AR.VCaP_DHAT_2H 283 bp overlap

ChIP VCaP_R1881 GSE32892.AR.VCaP_R1881 227 bp overlap

ChIP VCaP_R1881_4H GSE84432.AR.VCaP_R1881_4H 208 bp overlap

Ar 1 dataset

Motif DE_60h DE_60h-Ar_MA0007.4 16 bp overlap

BARX2 1 dataset

Motif DE_60h DE_60h-BARX2_MA1471.2 9 bp overlap

Bcl11B 1 dataset

Motif DE_60h DE_60h-Bcl11B_MA1989.2 9 bp overlap

CDX1 1 dataset

Motif DE_60h DE_60h-CDX1_MA0878.3 10 bp overlap

CHD7 2 datasets

ChIP WA01 ENCSR000AVA.CHD7.WA01 162 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 479 bp overlap

CUX1 1 dataset

Motif DE_60h DE_60h-CUX1_MA0754.3 9 bp overlap

CUX2 1 dataset

Motif DE_60h DE_60h-CUX2_MA0755.2 9 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF364PUR 251 bp overlap

DMRTA1 2 datasets

Motif DE_48h DE_48h-DMRTA1_MA1707.2 10 bp overlap

Motif DE_60h DE_60h-DMRTA1_MA1707.2 10 bp overlap

DMRTA2 3 datasets

Motif DE_48h DE_48h-DMRTA2_MA1478.2 6 bp overlap

Motif DE_60h DE_60h-DMRTA2_MA1478.2 6 bp overlap

E2F6 1 dataset

ChIP WA01 ENCSR000BSI.E2F6.WA01 148 bp overlap

ELF1 3 datasets

Motif DE_48h DE_48h-ELF1_MA0473.4 9 bp overlap

Motif DE_60h DE_60h-ELF1_MA0473.4 9 bp overlap

Motif DE_72h DE_72h-ELF1_MA0473.4 9 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 464 bp overlap

EP300 1 dataset

ChIP hESC GSE17917.EP300.hESC 293 bp overlap

EZH2 2 datasets

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 306 bp overlap

ChIP neural progenitor cell ENCFF018MKA 586 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 438 bp overlap

FERD3L 1 dataset

Motif DE_60h DE_60h-FERD3L_MA1485.1 14 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 515 bp overlap

ChIP DE DE-FOXA2-2 463 bp overlap

FOXE1 1 dataset

Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap

FOXF2 1 dataset

Motif DE_60h DE_60h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif DE_60h DE_60h-FOXG1_MA0613.1 8 bp overlap

FOXK1 1 dataset

Motif DE_60h DE_60h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_60h DE_60h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_60h DE_60h-FOXL1_MA0033.2 7 bp overlap

FOXN3 1 dataset

Motif DE_60h DE_60h-FOXN3_MA1489.1 8 bp overlap

FOXO4 1 dataset

Motif DE_60h DE_60h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_60h DE_60h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 248 bp overlap

FOXP2 1 dataset

Motif DE_60h DE_60h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_60h DE_60h-FOXP3_MA0850.1 7 bp overlap

Foxf1 1 dataset

Motif DE_60h DE_60h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_60h DE_60h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif DE_60h DE_60h-Foxj3_MA0851.2 9 bp overlap

Foxo1 1 dataset

Motif DE_60h DE_60h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_60h DE_60h-Foxo3_MA0157.4 7 bp overlap

GABPA 3 datasets

Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap

Motif DE_60h DE_60h-GABPA_MA0062.4 10 bp overlap

Motif DE_72h DE_72h-GABPA_MA0062.4 10 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 539 bp overlap

ChIP DE DE-GATA4-2 613 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 494 bp overlap

ChIP DE DE-GATA6-2 641 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 524 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 483 bp overlap

GLI3 3 datasets

Motif DE_48h DE_48h-GLI3_MA1491.3 15 bp overlap

Motif DE_60h DE_60h-GLI3_MA1491.3 15 bp overlap

Motif DE_72h DE_72h-GLI3_MA1491.3 15 bp overlap

Gfi1B 1 dataset

Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap

HDAC2 2 datasets

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 118 bp overlap

HOXB13 1 dataset

ChIP prostate_P13_T GSE130408.HOXB13.prostate_P13_T 64 bp overlap

HOXD11 1 dataset

Motif DE_60h DE_60h-HOXD11_MA0908.2 9 bp overlap

Ikzf3 3 datasets

Motif DE_48h DE_48h-Ikzf3_MA1992.2 9 bp overlap

Motif DE_60h DE_60h-Ikzf3_MA1992.2 9 bp overlap

Motif DE_72h DE_72h-Ikzf3_MA1992.2 9 bp overlap

MZF1 1 dataset

Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap

NANOG 7 datasets

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 240 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 474 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 226 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 480 bp overlap

ChIP hESC GSE18292.NANOG.hESC 375 bp overlap

ChIP hESC GSE20650.NANOG.hESC 222 bp overlap

NFATC3 1 dataset

Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap

Nfatc1 1 dataset

Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 1 dataset

Motif DE_60h DE_60h-Nfatc2_MA0152.3 8 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_60h DE_60h-POU2F1SOX2_MA1962.1 17 bp overlap

POU5F1 2 datasets

ChIP HUES-8 GSE109524.POU5F1.HUES-8 358 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 363 bp overlap

RUNX2 1 dataset

Motif DE_60h DE_60h-RUNX2_MA0511.2 9 bp overlap

Runx1 1 dataset

Motif DE_60h DE_60h-Runx1_MA0002.3 9 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 160 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 595 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 305 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 162 bp overlap

SMAD3-HIF1A 1 dataset

ChIP PC-3_hypoxia GSE106305.SMAD3-HIF1A.PC-3_hypoxia 174 bp overlap

SMARCA4 4 datasets

ChIP NPC GSE122631.SMARCA4.NPC 324 bp overlap

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 284 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 409 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 216 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 306 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 291 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 242 bp overlap

SOX10 1 dataset

Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 361 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 567 bp overlap

SOX2 3 datasets

ChIP HNSC GSE69479.SOX2.HNSC 686 bp overlap

ChIP hESC GSE18292.SOX2.hESC 214 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 188 bp overlap

SOX21 2 datasets

Motif DE_60h DE_60h-SOX21_MA0866.1 15 bp overlap

ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 402 bp overlap

SOX4 1 dataset

Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap

SRY 1 dataset

Motif DE_60h DE_60h-SRY_MA0084.2 7 bp overlap

Sox17 1 dataset

Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap

Sox7 1 dataset

Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap

Stat5a::Stat5b 2 datasets

Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap

Motif DE_60h DE_60h-Stat5aStat5b_MA0519.2 9 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 361 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 220 bp overlap

TCF7L1 1 dataset

Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap

USF1 1 dataset

ChIP WA01 ENCSR000BIU.USF1.WA01 255 bp overlap

YY1 1 dataset

ChIP WA01 ENCSR000BKD.YY1.WA01 143 bp overlap

ZKSCAN5 3 datasets

Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap

Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap

Motif DE_72h DE_72h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF140 1 dataset

Motif DE_60h DE_60h-ZNF140_MA1589.2 19 bp overlap

ZNF143 1 dataset

Motif DE_60h DE_60h-ZNF143_MA0088.2 16 bp overlap

ZNF16 1 dataset

Motif DE_60h DE_60h-ZNF16_MA1654.2 21 bp overlap

ZNF184 2 datasets

Motif DE_60h DE_60h-ZNF184_MA2120.1 13 bp overlap

ZNF189 1 dataset

Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 282 bp overlap

ZNF24 3 datasets

Motif DE_48h DE_48h-ZNF24_MA1124.1 13 bp overlap

Motif DE_60h DE_60h-ZNF24_MA1124.1 13 bp overlap

Motif DE_72h DE_72h-ZNF24_MA1124.1 13 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 317 bp overlap

ZNF549 1 dataset

Motif DE_60h DE_60h-ZNF549_MA1728.2 8 bp overlap

ZNF652 1 dataset

Motif DE_60h DE_60h-ZNF652_MA1657.2 9 bp overlap

ZNF667 2 datasets

Motif DE_48h DE_48h-ZNF667_MA1984.2 11 bp overlap

Motif DE_60h DE_60h-ZNF667_MA1984.2 11 bp overlap

ZNF76 1 dataset

Motif DE_60h DE_60h-ZNF76_MA1716.2 17 bp overlap

ZNF768 1 dataset

Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap