chr6:167,244,852–167,245,449

chr6 : 167,244,852 – 167,245,449

597 bp 56 TFs 5 linked genes

This 597 bp open chromatin element is linked to 5 target genes and is bound by 56 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
HPAT5		16.9 kb	Distal	Multiome
ENSG00000285730		245.6 kb	Distal	Multiome
CEP43		245.8 kb	Distal	Multiome
ENSG00000227598		246.1 kb	Distal	Multiome
RNASET2		288.6 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

56 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 283 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 169 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 360 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 310 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 296 bp overlap

ChIP MV4-11_IBET151_5000nM GSE120715.BRD3.MV4-11_IBET151_5000nM 167 bp overlap

BRD4 5 datasets

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 98 bp overlap

ChIP cortical-interneuron GSE117508.BRD4.cortical-interneuron 65 bp overlap

ChIP cortical-interneuron_KCl-pos GSE117508.BRD4.cortical-interneuron_KCl-pos 167 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 158 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 257 bp overlap

CEBPB 1 dataset

ChIP H1 ENCFF871PTR 261 bp overlap

CHD7 3 datasets

ChIP H1 ENCFF126NLU 519 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 132 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 106 bp overlap

CREB1 2 datasets

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 92 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 167 bp overlap

CTCF 6 datasets

ChIP HAP1_clone21 GSE152721.CTCF.HAP1_clone21 163 bp overlap

ChIP HAP1_clone21_CTCF-TSS-CRISPR_1 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_1 175 bp overlap

ChIP brain ENCFF685VRG 556 bp overlap

ChIP neural ENCSR822CEA.CTCF.neural 502 bp overlap

ChIP neural cell ENCFF335ADI 178 bp overlap

ChIP neural cell ENCFF335ADI 273 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 400 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 274 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 91 bp overlap

EP300 4 datasets

ChIP H1 ENCFF927IYK 297 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 193 bp overlap

ChIP neural ENCSR843ZUP.EP300.neural 263 bp overlap

ChIP neural cell ENCFF442QNK 118 bp overlap

ChIP GM23338 ENCFF701IZH 377 bp overlap

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 190 bp overlap

HDAC2 2 datasets

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 149 bp overlap

Hand1::Tcf3 1 dataset

Motif ES_0h ES_0h-Hand1Tcf3_MA0092.2 9 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 331 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 335 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 373 bp overlap

KMT2A 1 dataset

ChIP L826 GSE83671.KMT2A.L826 68 bp overlap

ChIP H1 ENCFF914VQY 357 bp overlap

MEIS1 1 dataset

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 561 bp overlap

MYOD1 1 dataset

ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 181 bp overlap

NANOG 11 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 288 bp overlap

ChIP H1 ENCFF747ZPQ 96 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 597 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 597 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 293 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 597 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 597 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 597 bp overlap

ChIP hESC GSE20650.NANOG.hESC 180 bp overlap

ChIP hESC GSE18292.NANOG.hESC 125 bp overlap

NIPBL 6 datasets

ChIP WA09 GSE105028.NIPBL.WA09 430 bp overlap

ChIP WA09_heat-shock GSE105028.NIPBL.WA09_heat-shock 277 bp overlap

ChIP hESC GSE64758.NIPBL.hESC 229 bp overlap

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 236 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 433 bp overlap

ChIP hESC_activin GSE64758.NIPBL.hESC_activin 227 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH3 GSE83726.PAX3-FOXO1.RH3 96 bp overlap

ChIP fetal_testis GSE100639.PAX5.fetal_testis 181 bp overlap

ChIP RCH-ACV GSE85988.PBX1.RCH-ACV 307 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 349 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 107 bp overlap

POU5F1 12 datasets

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 597 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 597 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 138 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 349 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 400 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 231 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 597 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 596 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 314 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 288 bp overlap

RAD21 3 datasets

ChIP H1 ENCFF698EWO 241 bp overlap

ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 171 bp overlap

ChIP neural ENCSR198ZYJ.RAD21.neural 281 bp overlap

ChIP neural ENCSR000BTV.REST.neural 205 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 150 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 482 bp overlap

SIN3A 3 datasets

ChIP HUVEC-C GSE103245.SIN3A.HUVEC-C 162 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 148 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 270 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 153 bp overlap

SMAD2 2 datasets

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 382 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 261 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 336 bp overlap

SMAD3 1 dataset

ChIP hESC GSE29422.SMAD3.hESC 179 bp overlap

SMARCA4 5 datasets

ChIP NSC GSE125033.SMARCA4.NSC 194 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 293 bp overlap

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 347 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 572 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 494 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 328 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 577 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 526 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 478 bp overlap

SMC3 2 datasets

ChIP neural ENCSR404BPV.SMC3.neural 597 bp overlap

ChIP neural cell ENCFF795YGY 185 bp overlap

SOX2 3 datasets

ChIP hESC GSE69479.SOX2.hESC 191 bp overlap

ChIP hESC GSE18292.SOX2.hESC 95 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 361 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 233 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 56 bp overlap

SUZ12 1 dataset

ChIP Aska-SS GSE108025.SUZ12.Aska-SS 152 bp overlap

Motif ES_0h ES_0h-Six4_MA2001.2 7 bp overlap

ChIP hESC GSE122298.TBP.hESC 141 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 139 bp overlap

TCF3 2 datasets

ChIP NPC GSE154479.TCF3.NPC 597 bp overlap

ChIP RCH-ACV GSE85988.TCF3.RCH-ACV 228 bp overlap

TEAD4 3 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 288 bp overlap

Motif ES_0h ES_0h-TEAD4_MA0809.3 8 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 228 bp overlap

TP53 2 datasets

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 537 bp overlap

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 596 bp overlap

TRIM28 2 datasets

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 406 bp overlap

ChIP hESC GSE115387.TRIM28.hESC 178 bp overlap

ZNF143 1 dataset

ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 203 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 333 bp overlap

ZNF549 1 dataset

Motif ES_0h ES_0h-ZNF549_MA1728.2 8 bp overlap