chr1:99,959,336–99,959,871

chr1 : 99,959,336 – 99,959,871

535 bp 103 TFs 8 linked genes

This 535 bp open chromatin element is linked to 8 target genes and is bound by 103 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000228084		10.4 kb	Distal	Multiome
SLC35A3		10.4 kb	Distal	Multiome
MFSD14A		78.5 kb	Distal	Multiome
AGL		109.2 kb	Distal	Multiome
SASS6		173.3 kb	Distal	Multiome
TRMT13		173.6 kb	Distal	Multiome
FRRS1		193.0 kb	Distal	Multiome
DBT		290.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

103 transcription factors

ARID1B 1 dataset

ChIP K562 ENCFF938UXQ 378 bp overlap

BARX1 2 datasets

Motif DE_36h DE_36h-BARX1_MA0875.2 6 bp overlap

Motif DE_48h DE_48h-BARX1_MA0875.2 6 bp overlap

Motif DE_36h DE_36h-BSX_MA0876.2 6 bp overlap

Motif DE_48h DE_48h-BSX_MA0876.2 6 bp overlap

CBFA2T3 1 dataset

ChIP K562 ENCFF673OEZ 371 bp overlap

DLX1 2 datasets

Motif DE_36h DE_36h-DLX1_MA0879.3 6 bp overlap

Motif DE_48h DE_48h-DLX1_MA0879.3 6 bp overlap

DLX6 2 datasets

Motif DE_36h DE_36h-DLX6_MA0882.2 6 bp overlap

Motif DE_48h DE_48h-DLX6_MA0882.2 6 bp overlap

DMBX1 1 dataset

ChIP K562 ENCFF972HXB 242 bp overlap

DMRTA2 1 dataset

Motif DE_48h DE_48h-DMRTA2_MA1478.2 6 bp overlap

Dlx2 2 datasets

Motif DE_36h DE_36h-Dlx2_MA0885.3 8 bp overlap

Motif DE_48h DE_48h-Dlx2_MA0885.3 8 bp overlap

Dlx3 2 datasets

Motif DE_36h DE_36h-Dlx3_MA0880.2 6 bp overlap

Motif DE_48h DE_48h-Dlx3_MA0880.2 6 bp overlap

Dlx4 2 datasets

Motif DE_36h DE_36h-Dlx4_MA0881.2 6 bp overlap

Motif DE_48h DE_48h-Dlx4_MA0881.2 6 bp overlap

Dlx5 2 datasets

Motif DE_36h DE_36h-Dlx5_MA1476.3 8 bp overlap

Motif DE_48h DE_48h-Dlx5_MA1476.3 8 bp overlap

ERF::FOXI1 1 dataset

Motif DE_48h DE_48h-ERFFOXI1_MA1935.2 10 bp overlap

ETV5::HOXA2 2 datasets

Motif DE_36h DE_36h-ETV5HOXA2_MA1948.2 12 bp overlap

Motif DE_48h DE_48h-ETV5HOXA2_MA1948.2 12 bp overlap

FIGLA 1 dataset

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

FOXA1 1 dataset

Motif DE_48h DE_48h-FOXA1_MA0148.5 8 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 535 bp overlap

ChIP DE DE-FOXA2-2 468 bp overlap

Motif DE_48h DE_48h-FOXA2_MA0047.4 8 bp overlap

FOXA3 1 dataset

Motif DE_48h DE_48h-FOXA3_MA1683.2 7 bp overlap

FOXB1 1 dataset

Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif DE_48h DE_48h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap

FOXD1 1 dataset

Motif DE_48h DE_48h-FOXD1_MA0031.2 7 bp overlap

FOXD2 1 dataset

Motif DE_48h DE_48h-FOXD2_MA0847.4 11 bp overlap

FOXD3 1 dataset

Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap

FOXE1 1 dataset

Motif DE_48h DE_48h-FOXE1_MA1487.3 12 bp overlap

FOXF2 1 dataset

Motif DE_48h DE_48h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif DE_48h DE_48h-FOXG1_MA0613.1 8 bp overlap

FOXI1 1 dataset

Motif DE_48h DE_48h-FOXI1_MA0042.2 7 bp overlap

FOXK1 1 dataset

Motif DE_48h DE_48h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_48h DE_48h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_48h DE_48h-FOXL1_MA0033.2 7 bp overlap

FOXN3 1 dataset

Motif DE_48h DE_48h-FOXN3_MA1489.1 8 bp overlap

FOXO4 1 dataset

Motif DE_48h DE_48h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_48h DE_48h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

Motif DE_48h DE_48h-FOXP1_MA0481.4 7 bp overlap

FOXP2 1 dataset

Motif DE_48h DE_48h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_48h DE_48h-FOXP3_MA0850.1 7 bp overlap

FOXP4 1 dataset

Motif DE_48h DE_48h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif DE_48h DE_48h-FOXS1_MA2118.1 8 bp overlap

Foxf1 1 dataset

Motif DE_48h DE_48h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_48h DE_48h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif DE_48h DE_48h-Foxj3_MA0851.2 9 bp overlap

Foxl2 1 dataset

Motif DE_48h DE_48h-Foxl2_MA1607.2 10 bp overlap

Foxo1 1 dataset

Motif DE_48h DE_48h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_48h DE_48h-Foxo3_MA0157.4 7 bp overlap

Foxq1 1 dataset

Motif DE_48h DE_48h-Foxq1_MA0040.2 10 bp overlap

GATA1::TAL1 2 datasets

Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap

GATA4 7 datasets

ChIP DE DE-GATA4-1 470 bp overlap

ChIP DE DE-GATA4-2 518 bp overlap

Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 176 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 519 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 140 bp overlap

GATA5 4 datasets

Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap

Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

GATA6 15 datasets

ChIP DE DE-GATA6-1 472 bp overlap

ChIP DE DE-GATA6-2 528 bp overlap

Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 469 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 471 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 456 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 535 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 384 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 354 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 329 bp overlap

ChIP foregut GSE117136.GATA6.foregut 203 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 196 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 266 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 137 bp overlap

GBX2 2 datasets

Motif DE_36h DE_36h-GBX2_MA0890.2 6 bp overlap

Motif DE_48h DE_48h-GBX2_MA0890.2 6 bp overlap

Gata3 2 datasets

Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

HESX1 2 datasets

Motif DE_36h DE_36h-HESX1_MA0894.2 6 bp overlap

Motif DE_48h DE_48h-HESX1_MA0894.2 6 bp overlap

HOXA6 2 datasets

Motif DE_36h DE_36h-HOXA6_MA1497.2 7 bp overlap

Motif DE_48h DE_48h-HOXA6_MA1497.2 7 bp overlap

HOXA7 2 datasets

Motif DE_36h DE_36h-HOXA7_MA1498.3 6 bp overlap

Motif DE_48h DE_48h-HOXA7_MA1498.3 6 bp overlap

HOXB6 2 datasets

Motif DE_36h DE_36h-HOXB6_MA1500.2 7 bp overlap

Motif DE_48h DE_48h-HOXB6_MA1500.2 7 bp overlap

HOXB7 2 datasets

Motif DE_36h DE_36h-HOXB7_MA1501.2 7 bp overlap

Motif DE_48h DE_48h-HOXB7_MA1501.2 7 bp overlap

HOXB8 2 datasets

Motif DE_36h DE_36h-HOXB8_MA1502.2 7 bp overlap

Motif DE_48h DE_48h-HOXB8_MA1502.2 7 bp overlap

HOXD8 2 datasets

Motif DE_36h DE_36h-HOXD8_MA0910.3 7 bp overlap

Motif DE_48h DE_48h-HOXD8_MA0910.3 7 bp overlap

HOXD9 2 datasets

Motif DE_36h DE_36h-HOXD9_MA0913.3 9 bp overlap

Motif DE_48h DE_48h-HOXD9_MA0913.3 9 bp overlap

Hmx1 2 datasets

Motif DE_36h DE_36h-Hmx1_MA0896.2 9 bp overlap

Motif DE_48h DE_48h-Hmx1_MA0896.2 9 bp overlap

Hmx2 2 datasets

Motif DE_36h DE_36h-Hmx2_MA0897.2 15 bp overlap

Motif DE_48h DE_48h-Hmx2_MA0897.2 15 bp overlap

Hmx3 2 datasets

Motif DE_36h DE_36h-Hmx3_MA0898.2 9 bp overlap

Motif DE_48h DE_48h-Hmx3_MA0898.2 9 bp overlap

IKZF1 1 dataset

Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 244 bp overlap

LBX2 2 datasets

Motif DE_36h DE_36h-LBX2_MA0699.2 6 bp overlap

Motif DE_48h DE_48h-LBX2_MA0699.2 6 bp overlap

LHX2 2 datasets

Motif DE_36h DE_36h-LHX2_MA0700.3 6 bp overlap

Motif DE_48h DE_48h-LHX2_MA0700.3 6 bp overlap

MEIS1 2 datasets

Motif DE_36h DE_36h-MEIS1_MA1639.2 9 bp overlap

Motif DE_48h DE_48h-MEIS1_MA1639.2 9 bp overlap

MEIS2 2 datasets

Motif DE_36h DE_36h-MEIS2_MA1640.2 9 bp overlap

Motif DE_48h DE_48h-MEIS2_MA1640.2 9 bp overlap

MSX1 2 datasets

Motif DE_36h DE_36h-MSX1_MA0666.3 6 bp overlap

Motif DE_48h DE_48h-MSX1_MA0666.3 6 bp overlap

MSX2 2 datasets

Motif DE_36h DE_36h-MSX2_MA0708.3 6 bp overlap

Motif DE_48h DE_48h-MSX2_MA0708.3 6 bp overlap

Mecom 2 datasets

Motif DE_36h DE_36h-Mecom_MA0029.2 11 bp overlap

Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap

Msx3 2 datasets

Motif DE_36h DE_36h-Msx3_MA0709.2 6 bp overlap

Motif DE_48h DE_48h-Msx3_MA0709.2 6 bp overlap

NFATC3 1 dataset

Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap

NFE2L1 1 dataset

ChIP K562 ENCFF138UHK 184 bp overlap

Nfatc1 1 dataset

Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap

Nobox 2 datasets

Motif DE_36h DE_36h-Nobox_MA0125.2 6 bp overlap

Motif DE_48h DE_48h-Nobox_MA0125.2 6 bp overlap

PBX1 2 datasets

Motif DE_36h DE_36h-PBX1_MA0070.2 9 bp overlap

Motif DE_48h DE_48h-PBX1_MA0070.2 9 bp overlap

PBX2 2 datasets

Motif DE_36h DE_36h-PBX2_MA1113.3 9 bp overlap

Motif DE_48h DE_48h-PBX2_MA1113.3 9 bp overlap

PHOX2A 2 datasets

Motif DE_36h DE_36h-PHOX2A_MA0713.1 11 bp overlap

Motif DE_48h DE_48h-PHOX2A_MA0713.1 11 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 284 bp overlap

PTTG1 1 dataset

ChIP K562 ENCFF017KRM 190 bp overlap

Motif DE_36h DE_36h-RAX_MA0718.2 6 bp overlap

Motif DE_48h DE_48h-RAX_MA0718.2 6 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 535 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 535 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 535 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 483 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 535 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 511 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 535 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 535 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 256 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 383 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 508 bp overlap

STAT1 1 dataset

Motif DE_48h DE_48h-STAT1_MA0137.4 9 bp overlap

Motif DE_48h DE_48h-Spz1_MA0111.1 11 bp overlap

Stat4 1 dataset

Motif DE_48h DE_48h-Stat4_MA0518.2 10 bp overlap

Stat5a 2 datasets

Motif DE_36h DE_36h-Stat5a_MA1624.2 9 bp overlap

Motif DE_48h DE_48h-Stat5a_MA1624.2 9 bp overlap

ChIP K562 ENCFF620GMX 350 bp overlap

TCF12 1 dataset

ChIP K562 ENCFF931DJY 373 bp overlap

Motif DE_48h DE_48h-TCF4_MA0830.3 8 bp overlap

TRPS1 2 datasets

Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

ZNF136 2 datasets

Motif DE_36h DE_36h-ZNF136_MA1588.1 15 bp overlap

Motif DE_48h DE_48h-ZNF136_MA1588.1 15 bp overlap

ZNF143 2 datasets

Motif DE_36h DE_36h-ZNF143_MA0088.2 16 bp overlap

Motif DE_48h DE_48h-ZNF143_MA0088.2 16 bp overlap

ZNF215 1 dataset

ChIP K562 ENCFF317MOH 216 bp overlap

ZNF281 1 dataset

ChIP K562 ENCFF594VNM 252 bp overlap

ZNF592 2 datasets

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 96 bp overlap

ChIP K562 ENCFF547OSS 213 bp overlap

ZNF770 2 datasets

ChIP HEK293 ENCFF468FCG 60 bp overlap

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 51 bp overlap