chr4 : 163,172,349 – 163,173,039

690 bp 85 TFs 1 linked gene

This 690 bp open chromatin element is linked to NAF1 and is bound by 85 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
NAF1		5.5 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

85 transcription factors

AR 1 dataset

ChIP LNCaP_androgen-N_hypoxia-N GSE114732.AR.LNCaP_androgen-N_hypoxia-N 176 bp overlap

ARGFX 1 dataset

Motif DE_12h DE_12h-ARGFX_MA1463.2 8 bp overlap

BARX1 1 dataset

Motif DE_12h DE_12h-BARX1_MA0875.2 6 bp overlap

BSX 1 dataset

Motif DE_12h DE_12h-BSX_MA0876.2 6 bp overlap

DLX1 1 dataset

Motif DE_12h DE_12h-DLX1_MA0879.3 6 bp overlap

DLX6 1 dataset

Motif DE_12h DE_12h-DLX6_MA0882.2 6 bp overlap

DUX4 1 dataset

Motif DE_12h DE_12h-DUX4_MA0468.1 11 bp overlap

Dlx2 1 dataset

Motif DE_12h DE_12h-Dlx2_MA0885.3 8 bp overlap

Dlx3 1 dataset

Motif DE_12h DE_12h-Dlx3_MA0880.2 6 bp overlap

Dlx4 1 dataset

Motif DE_12h DE_12h-Dlx4_MA0881.2 6 bp overlap

Dlx5 1 dataset

Motif DE_12h DE_12h-Dlx5_MA1476.3 8 bp overlap

Dux 1 dataset

Motif DE_12h DE_12h-Dux_MA0611.3 11 bp overlap

EHF 1 dataset

Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap

ELF3 1 dataset

Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap

ETV2 1 dataset

Motif DE_12h DE_12h-ETV2_MA0762.2 9 bp overlap

ETV7 1 dataset

Motif DE_12h DE_12h-ETV7_MA1708.2 9 bp overlap

Erg 1 dataset

Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap

FEZF1 2 datasets

ChIP HEK293 ENCFF528YED 365 bp overlap

ChIP HEK293 GSE76494.FEZF1.HEK293 162 bp overlap

GABPA 1 dataset

Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap

GATA4 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 120 bp overlap

GATA6 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 434 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 265 bp overlap

GBX2 1 dataset

Motif DE_12h DE_12h-GBX2_MA0890.2 6 bp overlap

GRHL1 1 dataset

Motif DE_12h DE_12h-GRHL1_MA0647.2 10 bp overlap

GRHL2 1 dataset

Motif DE_12h DE_12h-GRHL2_MA1105.3 8 bp overlap

HESX1 1 dataset

Motif DE_12h DE_12h-HESX1_MA0894.2 6 bp overlap

HOXA7 1 dataset

Motif DE_12h DE_12h-HOXA7_MA1498.3 6 bp overlap

Hnf1A 1 dataset

Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap

LBX2 1 dataset

Motif DE_12h DE_12h-LBX2_MA0699.2 6 bp overlap

LHX2 1 dataset

Motif DE_12h DE_12h-LHX2_MA0700.3 6 bp overlap

Lef1 2 datasets

Motif DE_12h DE_12h-Lef1_MA0768.3 8 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MSX1 1 dataset

Motif DE_12h DE_12h-MSX1_MA0666.3 6 bp overlap

MSX2 1 dataset

Motif DE_12h DE_12h-MSX2_MA0708.3 6 bp overlap

Msx3 1 dataset

Motif DE_12h DE_12h-Msx3_MA0709.2 6 bp overlap

NFATC3 2 datasets

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

NFIB 1 dataset

Motif DE_12h DE_12h-NFIB_MA1643.2 17 bp overlap

NFIC 4 datasets

Motif DE_12h DE_12h-NFIC_MA1527.2 15 bp overlap

ChIP Ishikawa ENCSR000BUT.NFIC.Ishikawa 159 bp overlap

ChIP K-562 ENCSR796ITY.NFIC.K-562 410 bp overlap

ChIP K562 ENCFF167YID 333 bp overlap

NFIC::TLX1 1 dataset

Motif DE_12h DE_12h-NFICTLX1_MA0119.1 14 bp overlap

NFIL3 1 dataset

Motif DE_12h DE_12h-NFIL3_MA0025.3 9 bp overlap

NFIX 1 dataset

Motif DE_12h DE_12h-NFIX_MA1528.2 14 bp overlap

NOTCH3 1 dataset

ChIP TALL-1_GSI GSE104261.NOTCH3.TALL-1_GSI 178 bp overlap

NR3C1 1 dataset

ChIP Ishikawa ENCSR000BJC.NR3C1.Ishikawa 121 bp overlap

Nfat5 1 dataset

Motif DE_12h DE_12h-Nfat5_MA0606.3 8 bp overlap

Nfatc1 2 datasets

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 2 datasets

Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap

Nobox 1 dataset

Motif DE_12h DE_12h-Nobox_MA0125.2 6 bp overlap

ONECUT3 1 dataset

Motif DE_12h DE_12h-ONECUT3_MA0757.2 12 bp overlap

PAX7 1 dataset

ChIP H9_DOX GSE98976.PAX7.H9_DOX 243 bp overlap

PHOX2A 1 dataset

Motif DE_12h DE_12h-PHOX2A_MA0713.1 11 bp overlap

PHOX2B 1 dataset

Motif DE_12h DE_12h-PHOX2B_MA0681.3 12 bp overlap

PROP1 1 dataset

Motif DE_12h DE_12h-PROP1_MA0715.1 11 bp overlap

Pax7 1 dataset

Motif DE_12h DE_12h-Pax7_MA0680.3 10 bp overlap

Prdm5 1 dataset

Motif DE_12h DE_12h-Prdm5_MA1999.2 11 bp overlap

RARA 1 dataset

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 283 bp overlap

RAX 1 dataset

Motif DE_12h DE_12h-RAX_MA0718.2 6 bp overlap

RBPJ 1 dataset

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

Rhox11 1 dataset

Motif DE_12h DE_12h-Rhox11_MA0629.2 9 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

SRF 1 dataset

ChIP Ishikawa ENCSR000BTD.SRF.Ishikawa 176 bp overlap

STAT1 1 dataset

Motif DE_12h DE_12h-STAT1_MA0137.4 9 bp overlap

STAT1::STAT2 1 dataset

Motif DE_12h DE_12h-STAT1STAT2_MA0517.2 13 bp overlap

STAT3 1 dataset

Motif DE_12h DE_12h-STAT3_MA0144.3 9 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

Stat5b 1 dataset

Motif DE_12h DE_12h-Stat5b_MA1625.2 9 bp overlap

TCF4 1 dataset

ChIP LS180_125 GSE31939.TCF4.LS180_125 111 bp overlap

TCF7 1 dataset

Motif DE_12h DE_12h-TCF7_MA0769.3 7 bp overlap

TCF7L1 1 dataset

Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 2 datasets

Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap

ChIP HCT-116 ENCSR000EUV.TCF7L2.HCT-116 137 bp overlap

TEAD1 3 datasets

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

ChIP HEK293_siE1A GSE130135.TEAD1.HEK293_siE1A 114 bp overlap

ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 224 bp overlap

TEAD2 1 dataset

Motif DE_12h DE_12h-TEAD2_MA1121.2 7 bp overlap

TEAD3 1 dataset

Motif DE_12h DE_12h-TEAD3_MA0808.1 8 bp overlap

TEAD4 1 dataset

Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap

TFCP2 1 dataset

Motif DE_12h DE_12h-TFCP2_MA1968.2 9 bp overlap

XRCC5 1 dataset

ChIP K-562 GSE120104.XRCC5.K-562 146 bp overlap

ZBTB24 1 dataset

Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 263 bp overlap

ZNF189 1 dataset

Motif DE_12h DE_12h-ZNF189_MA1725.2 9 bp overlap

ZNF214 1 dataset

Motif DE_12h DE_12h-ZNF214_MA1975.2 13 bp overlap

ZNF384 1 dataset

Motif DE_12h DE_12h-ZNF384_MA1125.2 8 bp overlap

ZNF530 1 dataset

Motif DE_12h DE_12h-ZNF530_MA1981.2 14 bp overlap

ZNF701 1 dataset

Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap

ZNF768 1 dataset

Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap

Zfp809 1 dataset

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap

Zic1::Zic2 1 dataset

Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap

Zic3 1 dataset

Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap