chr3 : 40,291,090 – 40,292,047
957 bp 87 TFs 5 linked genes
This 957 bp open chromatin element is linked to 5 target genes and is bound by 87 transcription factors.
Linked Genes
5 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
EIF1B 18.0 kb Distal Multiome
EIF1B-AS1 161.5 kb Distal Multiome
RPL14 165.7 kb Distal Multiome
ZNF620 214.4 kb Distal Multiome
ZNF621 233.3 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:40,286,090 – 40,297,047
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
87 transcription factors
Source
Cell type
BCL6 3 datasets
Motif DE_48h DE_48h-BCL6_MA0463.3 13 bp overlap
Motif DE_60h DE_60h-BCL6_MA0463.3 13 bp overlap
Motif DE_72h DE_72h-BCL6_MA0463.3 13 bp overlap
BRD4 2 datasets
ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 282 bp overlap
ChIP LNCaP-clone-FGC_DHT-Enzalutamide GSE118247.BRD4.LNCaP-clone-FGC_DHT-Enzalutamide 130 bp overlap
CBX3 1 dataset
ChIP K562 ENCFF410AQU 431 bp overlap
CBX5 1 dataset
ChIP K-562 ENCSR272JAT.CBX5.K-562 112 bp overlap
CHD8 1 dataset
ChIP T-47D GSE62428.CHD8.T-47D 149 bp overlap
CTCF 2 datasets
ChIP IMR-90_Ctrl GSE125639.CTCF.IMR-90_Ctrl 187 bp overlap
ChIP T-47D_NaCl-triptolide GSE111923.CTCF.T-47D_NaCl-triptolide 85 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF031ISE 251 bp overlap
DMRTA2 4 datasets
Motif DE_36h DE_36h-DMRTA2_MA1478.2 6 bp overlap
Motif DE_48h DE_48h-DMRTA2_MA1478.2 6 bp overlap
Motif DE_60h DE_60h-DMRTA2_MA1478.2 6 bp overlap
Motif DE_72h DE_72h-DMRTA2_MA1478.2 6 bp overlap
DPRX 3 datasets
Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap
Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap
Motif DE_72h DE_72h-DPRX_MA1480.2 9 bp overlap
Ddit3::Cebpa 3 datasets
Motif DE_48h DE_48h-Ddit3Cebpa_MA0019.2 10 bp overlap
Motif DE_60h DE_60h-Ddit3Cebpa_MA0019.2 10 bp overlap
Motif DE_72h DE_72h-Ddit3Cebpa_MA0019.2 10 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 268 bp overlap
ESR1 2 datasets
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 96 bp overlap
ChIP MCF-7_E2-ICI GSE67295.ESR1.MCF-7_E2-ICI 171 bp overlap
ESRRG 1 dataset
ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 233 bp overlap
ETS1 1 dataset
ChIP SCC-25 GSE109884.ETS1.SCC-25 59 bp overlap
FEZF2 3 datasets
Motif DE_48h DE_48h-FEZF2_MA2341.1 8 bp overlap
Motif DE_60h DE_60h-FEZF2_MA2341.1 8 bp overlap
Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 509 bp overlap
ChIP DE DE-FOXA2-2 429 bp overlap
FOXC1 3 datasets
Motif DE_48h DE_48h-FOXC1_MA0032.2 11 bp overlap
Motif DE_60h DE_60h-FOXC1_MA0032.2 11 bp overlap
Motif DE_72h DE_72h-FOXC1_MA0032.2 11 bp overlap
FOXC2 3 datasets
Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap
Motif DE_60h DE_60h-FOXC2_MA0846.2 11 bp overlap
Motif DE_72h DE_72h-FOXC2_MA0846.2 11 bp overlap
FOXD3 3 datasets
Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap
Motif DE_60h DE_60h-FOXD3_MA0041.3 14 bp overlap
Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap
FOXE1 3 datasets
Motif DE_48h DE_48h-FOXE1_MA1487.3 12 bp overlap
Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap
Motif DE_72h DE_72h-FOXE1_MA1487.3 12 bp overlap
FOXN3 3 datasets
Motif DE_48h DE_48h-FOXN3_MA1489.1 8 bp overlap
Motif DE_60h DE_60h-FOXN3_MA1489.1 8 bp overlap
Motif DE_72h DE_72h-FOXN3_MA1489.1 8 bp overlap
FOXP2 3 datasets
Motif DE_48h DE_48h-FOXP2_MA0593.2 9 bp overlap
Motif DE_60h DE_60h-FOXP2_MA0593.2 9 bp overlap
Motif DE_72h DE_72h-FOXP2_MA0593.2 9 bp overlap
Foxl2 3 datasets
Motif DE_48h DE_48h-Foxl2_MA1607.2 10 bp overlap
Motif DE_60h DE_60h-Foxl2_MA1607.2 10 bp overlap
Motif DE_72h DE_72h-Foxl2_MA1607.2 10 bp overlap
GATA1::TAL1 3 datasets
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 1 dataset
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 154 bp overlap
GATA4 5 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 207 bp overlap
ChIP DE DE-GATA4-1 607 bp overlap
ChIP DE DE-GATA4-2 697 bp overlap
ChIP foregut GSE117136.GATA4.foregut 572 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 513 bp overlap
GATA6 15 datasets
ChIP AGS GSE51705.GATA6.AGS 205 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 132 bp overlap
ChIP DE DE-GATA6-1 563 bp overlap
ChIP DE DE-GATA6-2 697 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 539 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 638 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 385 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 690 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 662 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 537 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 524 bp overlap
ChIP foregut GSE117136.GATA6.foregut 619 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 360 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 506 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 458 bp overlap
GFI1 3 datasets
Motif DE_48h DE_48h-GFI1_MA0038.3 11 bp overlap
Motif DE_60h DE_60h-GFI1_MA0038.3 11 bp overlap
Motif DE_72h DE_72h-GFI1_MA0038.3 11 bp overlap
GSPT2 1 dataset
ChIP HEK293T GSE35197.GSPT2.HEK293T 67 bp overlap
GTF3C2 2 datasets
ChIP H9 GSE94418.GTF3C2.H9 185 bp overlap
ChIP H9 GSE94418.GTF3C2.H9 204 bp overlap
Gfi1B 3 datasets
Motif DE_48h DE_48h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_72h DE_72h-Gfi1B_MA0483.2 10 bp overlap
HIVEP1 1 dataset
ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 141 bp overlap
HNRNPLL 2 datasets
ChIP HepG2 ENCFF952XAB 117 bp overlap
ChIP HepG2 ENCFF952XAB 322 bp overlap
IRF3 3 datasets
Motif DE_48h DE_48h-IRF3_MA1418.2 17 bp overlap
Motif DE_60h DE_60h-IRF3_MA1418.2 17 bp overlap
Motif DE_72h DE_72h-IRF3_MA1418.2 17 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 436 bp overlap
LIN54 3 datasets
Motif DE_48h DE_48h-LIN54_MA0619.2 7 bp overlap
Motif DE_60h DE_60h-LIN54_MA0619.2 7 bp overlap
Motif DE_72h DE_72h-LIN54_MA0619.2 7 bp overlap
Lef1 3 datasets
Motif DE_48h DE_48h-Lef1_MA0768.3 8 bp overlap
Motif DE_60h DE_60h-Lef1_MA0768.3 8 bp overlap
Motif DE_72h DE_72h-Lef1_MA0768.3 8 bp overlap
MAF1 1 dataset
ChIP THP-1_monocytes GSE96800.MAF1.THP-1_monocytes 153 bp overlap
MED1 1 dataset
ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 406 bp overlap
Mecom 3 datasets
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
NKX2-5 1 dataset
ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 242 bp overlap
NR5A1 4 datasets
Motif DE_36h DE_36h-NR5A1_MA1540.3 12 bp overlap
Motif DE_48h DE_48h-NR5A1_MA1540.3 12 bp overlap
Motif DE_60h DE_60h-NR5A1_MA1540.3 12 bp overlap
Motif DE_72h DE_72h-NR5A1_MA1540.3 12 bp overlap
NR6A1 4 datasets
Motif DE_36h DE_36h-NR6A1_MA1541.2 14 bp overlap
Motif DE_48h DE_48h-NR6A1_MA1541.2 14 bp overlap
Motif DE_60h DE_60h-NR6A1_MA1541.2 14 bp overlap
Motif DE_72h DE_72h-NR6A1_MA1541.2 14 bp overlap
OSR1 3 datasets
Motif DE_48h DE_48h-OSR1_MA1542.2 8 bp overlap
Motif DE_60h DE_60h-OSR1_MA1542.2 8 bp overlap
Motif DE_72h DE_72h-OSR1_MA1542.2 8 bp overlap
POU1F1 3 datasets
Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap
Motif DE_60h DE_60h-POU1F1_MA0784.3 14 bp overlap
Motif DE_72h DE_72h-POU1F1_MA0784.3 14 bp overlap
Prdm4 3 datasets
Motif DE_48h DE_48h-Prdm4_MA1647.3 11 bp overlap
Motif DE_60h DE_60h-Prdm4_MA1647.3 11 bp overlap
Motif DE_72h DE_72h-Prdm4_MA1647.3 11 bp overlap
RBPJ 3 datasets
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap
Rfx6 3 datasets
Motif DE_48h DE_48h-Rfx6_MA1724.2 9 bp overlap
Motif DE_60h DE_60h-Rfx6_MA1724.2 9 bp overlap
Motif DE_72h DE_72h-Rfx6_MA1724.2 9 bp overlap
SETDB1 3 datasets
ChIP HEK293 ENCFF676PLV 610 bp overlap
ChIP HEK293 ENCSR348AGV.SETDB1.HEK293 367 bp overlap
ChIP U2OS ENCSR000EYD.SETDB1.U2OS 367 bp overlap
SIX1 4 datasets
Motif DE_36h DE_36h-SIX1_MA1118.2 9 bp overlap
Motif DE_48h DE_48h-SIX1_MA1118.2 9 bp overlap
Motif DE_60h DE_60h-SIX1_MA1118.2 9 bp overlap
Motif DE_72h DE_72h-SIX1_MA1118.2 9 bp overlap
SIX2 4 datasets
Motif DE_36h DE_36h-SIX2_MA1119.2 11 bp overlap
Motif DE_48h DE_48h-SIX2_MA1119.2 11 bp overlap
Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap
Motif DE_72h DE_72h-SIX2_MA1119.2 11 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 283 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 809 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 462 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 395 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 334 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 436 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 554 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 227 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 505 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 498 bp overlap
SOX8 1 dataset
ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 201 bp overlap
SRY 1 dataset
Motif DE_72h DE_72h-SRY_MA0084.2 7 bp overlap
STAT1::STAT2 3 datasets
Motif DE_48h DE_48h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_72h DE_72h-STAT1STAT2_MA0517.2 13 bp overlap
Six4 4 datasets
Motif DE_36h DE_36h-Six4_MA2001.2 7 bp overlap
Motif DE_48h DE_48h-Six4_MA2001.2 7 bp overlap
Motif DE_60h DE_60h-Six4_MA2001.2 7 bp overlap
Motif DE_72h DE_72h-Six4_MA2001.2 7 bp overlap
Stat2 3 datasets
Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap
TBX5 2 datasets
ChIP G296S_4 GSE85628.TBX5.G296S_4 230 bp overlap
ChIP G296S_4 GSE85628.TBX5.G296S_4 287 bp overlap
TCF7 3 datasets
Motif DE_48h DE_48h-TCF7_MA0769.3 7 bp overlap
Motif DE_60h DE_60h-TCF7_MA0769.3 7 bp overlap
Motif DE_72h DE_72h-TCF7_MA0769.3 7 bp overlap
TEAD1 4 datasets
Motif DE_36h DE_36h-TEAD1_MA0090.4 9 bp overlap
Motif DE_48h DE_48h-TEAD1_MA0090.4 9 bp overlap
Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap
Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap
TEAD2 4 datasets
Motif DE_36h DE_36h-TEAD2_MA1121.2 7 bp overlap
Motif DE_48h DE_48h-TEAD2_MA1121.2 7 bp overlap
Motif DE_60h DE_60h-TEAD2_MA1121.2 7 bp overlap
Motif DE_72h DE_72h-TEAD2_MA1121.2 7 bp overlap
TEAD3 4 datasets
Motif DE_36h DE_36h-TEAD3_MA0808.1 8 bp overlap
Motif DE_48h DE_48h-TEAD3_MA0808.1 8 bp overlap
Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap
Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap
TEAD4 4 datasets
Motif DE_36h DE_36h-TEAD4_MA0809.3 8 bp overlap
Motif DE_48h DE_48h-TEAD4_MA0809.3 8 bp overlap
Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap
Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap
TP63 4 datasets
ChIP BxPC-3 GSE115461.TP63.BxPC-3 96 bp overlap
ChIP JHU-029 GSE88859.TP63.JHU-029 53 bp overlap
ChIP SUIT-2 GSE115461.TP63.SUIT-2 190 bp overlap
ChIP keratinocyte_D7 GSE59824.TP63.keratinocyte_D7 64 bp overlap
TP73_TA 1 dataset
ChIP SaOS-2 GSE15780.TP73_TA.SaOS-2 99 bp overlap
TRIM28 3 datasets
ChIP AF22 GSE84259.TRIM28.AF22 343 bp overlap
ChIP K-562 ENCSR474CVP.TRIM28.K-562 352 bp overlap
ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 412 bp overlap
ZBTB18 4 datasets
Motif DE_36h DE_36h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_60h DE_60h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap
ZBTB7A 1 dataset
ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 101 bp overlap
ZIM3 3 datasets
Motif DE_48h DE_48h-ZIM3_MA1709.2 11 bp overlap
Motif DE_60h DE_60h-ZIM3_MA1709.2 11 bp overlap
Motif DE_72h DE_72h-ZIM3_MA1709.2 11 bp overlap
ZNF143 1 dataset
ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 145 bp overlap
ZNF213 3 datasets
Motif DE_48h DE_48h-ZNF213_MA2121.1 12 bp overlap
Motif DE_60h DE_60h-ZNF213_MA2121.1 12 bp overlap
Motif DE_72h DE_72h-ZNF213_MA2121.1 12 bp overlap
ZNF214 5 datasets
Motif DE_48h DE_48h-ZNF214_MA1975.2 13 bp overlap
Motif DE_60h DE_60h-ZNF214_MA1975.2 13 bp overlap
Motif DE_60h DE_60h-ZNF214_MA1975.2 13 bp overlap
Motif DE_72h DE_72h-ZNF214_MA1975.2 13 bp overlap
Motif DE_72h DE_72h-ZNF214_MA1975.2 13 bp overlap
ZNF324 4 datasets
Motif DE_36h DE_36h-ZNF324_MA1977.2 14 bp overlap
Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap
Motif DE_60h DE_60h-ZNF324_MA1977.2 14 bp overlap
Motif DE_72h DE_72h-ZNF324_MA1977.2 14 bp overlap
ZNF384 3 datasets
Motif DE_48h DE_48h-ZNF384_MA1125.2 8 bp overlap
Motif DE_60h DE_60h-ZNF384_MA1125.2 8 bp overlap
Motif DE_72h DE_72h-ZNF384_MA1125.2 8 bp overlap
ZNF416 3 datasets
Motif DE_48h DE_48h-ZNF416_MA1979.2 10 bp overlap
Motif DE_60h DE_60h-ZNF416_MA1979.2 10 bp overlap
Motif DE_72h DE_72h-ZNF416_MA1979.2 10 bp overlap
ZNF677 3 datasets
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap
Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap
ZNF687 1 dataset
ChIP HepG2 ENCFF653WIX 197 bp overlap
ZNF736 1 dataset
ChIP HEK293T GSE78099.ZNF736.HEK293T 120 bp overlap
ZNF93 4 datasets
Motif DE_36h DE_36h-ZNF93_MA1721.2 14 bp overlap
Motif DE_48h DE_48h-ZNF93_MA1721.2 14 bp overlap
Motif DE_60h DE_60h-ZNF93_MA1721.2 14 bp overlap
Motif DE_72h DE_72h-ZNF93_MA1721.2 14 bp overlap
Zic1::Zic2 4 datasets
Motif DE_36h DE_36h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap
Zic2 2 datasets
Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap
Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap
Zic3 4 datasets
Motif DE_36h DE_36h-Zic3_MA0697.3 7 bp overlap
Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap
Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap
Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap
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