Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

38 transcription factors

ATF2 1 dataset

ChIP HepG2 ENCFF955VER 91 bp overlap

ATF3 3 datasets

ChIP K-562 ENCSR028UIU.ATF3.K-562 97 bp overlap

ChIP K-562 ENCSR632DCH.ATF3.K-562 53 bp overlap

ChIP K562 ENCFF921JQW 239 bp overlap

ATF4 2 datasets

ChIP K-562 ENCSR145TSJ.ATF4.K-562 117 bp overlap

ChIP K562 ENCFF674KTF 90 bp overlap

ATF7 3 datasets

ChIP Hep-G2 ENCSR545FXC.ATF7.Hep-G2 60 bp overlap

ChIP HepG2 ENCFF470FKK 59 bp overlap

ChIP MCF-7 ENCFF578WKB 58 bp overlap

BRD4 2 datasets

ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 342 bp overlap

ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 201 bp overlap

CEBPB 1 dataset

ChIP K562 ENCFF584CTB 134 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 103 bp overlap

CEBPG 1 dataset

ChIP K562 ENCFF783ADE 141 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF896HSY 166 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 275 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 327 bp overlap

FOXL2 1 dataset

ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 178 bp overlap

GATA1 2 datasets

ChIP K-562 GSE107726.GATA1.K-562 202 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 190 bp overlap

GATA2 1 dataset

ChIP WA09 GSE105081.GATA2.WA09 180 bp overlap

GATA4 8 datasets

ChIP DE DE-GATA4-1 421 bp overlap

ChIP DE DE-GATA4-2 499 bp overlap

Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 499 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 350 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 287 bp overlap

GATA5 3 datasets

Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 21 datasets

ChIP AGS GSE51705.GATA6.AGS 251 bp overlap

ChIP AGS GSE51936.GATA6.AGS 102 bp overlap

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 258 bp overlap

ChIP DE DE-GATA6-1 499 bp overlap

ChIP DE DE-GATA6-2 499 bp overlap

Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 499 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 499 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 401 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 405 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 499 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 499 bp overlap

ChIP YCC-3 GSE51705.GATA6.YCC-3 244 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 499 bp overlap

ChIP foregut GSE117136.GATA6.foregut 405 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 422 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 377 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 442 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 306 bp overlap

Gata3 3 datasets

Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

ISL2 1 dataset

Motif DE_72h DE_72h-ISL2_MA0914.2 6 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 248 bp overlap

JUND 1 dataset

ChIP HepG2 ENCFF869OPW 51 bp overlap

MZF1 1 dataset

Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap

NFATC1 1 dataset

ChIP GM12878 ENCSR000BQL.NFATC1.GM12878 183 bp overlap

NR1D1 1 dataset

Motif DE_72h DE_72h-NR1D1_MA1531.2 14 bp overlap

NR1D2 1 dataset

Motif DE_72h DE_72h-NR1D2_MA1532.2 15 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 438 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 422 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 371 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 141 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 342 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 338 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 345 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 342 bp overlap

SOX6 1 dataset

ChIP K-562 ENCSR788RSW.SOX6.K-562 205 bp overlap

SUPT6H 1 dataset

ChIP HCT-116_Inhibitor GSE130509.SUPT6H.HCT-116_Inhibitor 230 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 182 bp overlap

TBX20 3 datasets

Motif DE_36h DE_36h-TBX20_MA0689.1 11 bp overlap

Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap

Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap

TRPS1 3 datasets

Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

ZBTB24 2 datasets

Motif DE_36h DE_36h-ZBTB24_MA2330.1 10 bp overlap

Motif DE_72h DE_72h-ZBTB24_MA2330.1 10 bp overlap

ZEB2 1 dataset

ChIP K-562 ENCSR004GKA.ZEB2.K-562 248 bp overlap

ZKSCAN1 3 datasets

Motif DE_36h DE_36h-ZKSCAN1_MA1585.2 9 bp overlap

Motif DE_48h DE_48h-ZKSCAN1_MA1585.2 9 bp overlap

Motif DE_72h DE_72h-ZKSCAN1_MA1585.2 9 bp overlap

ZNF140 2 datasets

Motif DE_36h DE_36h-ZNF140_MA1589.2 19 bp overlap

Motif DE_72h DE_72h-ZNF140_MA1589.2 19 bp overlap

ZNF708 3 datasets

Motif DE_36h DE_36h-ZNF708_MA1730.2 9 bp overlap

Motif DE_48h DE_48h-ZNF708_MA1730.2 9 bp overlap

Motif DE_72h DE_72h-ZNF708_MA1730.2 9 bp overlap

Gene	Dist. to TSS	Distance	Link type
ITSN2	80.1 kb	Distal	Multiome
TP53I3	195.2 kb	Distal	Multiome
FAM228B	203.4 kb	Distal	Multiome
SF3B6	204.0 kb	Distal	Multiome
NCOA1	210.9 kb	Distal	Multiome
FKBP1B	230.6 kb	Distal	Multiome
WDCP	233.0 kb	Distal	Multiome

Genome Browser