chr18 : 5,287,727 – 5,288,731

1,004 bp 74 TFs 1 linked gene

This 1.0 kb open chromatin element is linked to ZBTB14 and is bound by 74 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ZBTB14		7.0 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

74 transcription factors

BACH2 1 dataset

ChIP OCI-Ly7 GSE44420.BACH2.OCI-Ly7 142 bp overlap

BCL6 6 datasets

ChIP B-cell_GERMINAL_CENTER GSE68349.BCL6.B-cell_GERMINAL_CENTER 524 bp overlap

ChIP B-cell_GERMINAL_CENTER GSE43350.BCL6.B-cell_GERMINAL_CENTER 356 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 123 bp overlap

ChIP OCI-Ly1 GSE107920.BCL6.OCI-Ly1 123 bp overlap

ChIP OCI-Ly7 GSE44420.BCL6.OCI-Ly7 142 bp overlap

ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 923 bp overlap

BCOR 1 dataset

ChIP B-cell_GERMINAL_CENTER GSE43350.BCOR.B-cell_GERMINAL_CENTER 260 bp overlap

BHLHE40 1 dataset

ChIP GM12878 ENCFF521IZR 125 bp overlap

BORCS8-MEF2B,MEF2B 1 dataset

ChIP GM12878 ENCFF427QAI 436 bp overlap

BRD4 3 datasets

ChIP Mutu-1_JQ1 GSE84213.BRD4.Mutu-1_JQ1 253 bp overlap

ChIP OCI-Ly1_DMSO GSE53601.BRD4.OCI-Ly1_DMSO 121 bp overlap

ChIP OCI-Ly1_JQ1 GSE53601.BRD4.OCI-Ly1_JQ1 240 bp overlap

CHD1 1 dataset

ChIP WA01 ENCSR000AQK.CHD1.WA01 172 bp overlap

CREBBP 2 datasets

ChIP tonsil_GCBC_p5 GSE89688.CREBBP.tonsil_GCBC_p5 400 bp overlap

ChIP tonsil_GCBc_p4 GSE89688.CREBBP.tonsil_GCBc_p4 443 bp overlap

CRX 1 dataset

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 445 bp overlap

Crx 1 dataset

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

DMRTA2 1 dataset

Motif DE_60h DE_60h-DMRTA2_MA1478.2 6 bp overlap

DPRX 1 dataset

Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap

Dmbx1 1 dataset

Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap

EBF1 5 datasets

ChIP GM12878 ENCFF167CZS 321 bp overlap

ChIP GM12878 ENCFF813OXE 265 bp overlap

ChIP LCL GSE75503.EBF1.LCL 317 bp overlap

ChIP MUTUL GSE75503.EBF1.MUTUL 266 bp overlap

ChIP MUTUL GSE75503.EBF1.MUTUL 434 bp overlap

EBF3 1 dataset

Motif DE_60h DE_60h-EBF3_MA1637.2 9 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 269 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 213 bp overlap

Ebf2 1 dataset

Motif DE_60h DE_60h-Ebf2_MA1604.2 9 bp overlap

FIGLA 1 dataset

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 953 bp overlap

ChIP DE DE-FOXA2-2 937 bp overlap

FOXO1 1 dataset

ChIP B-cell_GERMINAL_CENTER GSE68349.FOXO1.B-cell_GERMINAL_CENTER 325 bp overlap

FOXP1 2 datasets

ChIP B-cell_CD77-pos GSE114803.FOXP1.B-cell_CD77-pos 230 bp overlap

ChIP U2932 ERP010999.FOXP1.U2932 361 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 694 bp overlap

ChIP DE DE-GATA4-2 768 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 557 bp overlap

ChIP DE DE-GATA6-2 685 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 403 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 324 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 677 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 260 bp overlap

GSC 1 dataset

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

Hic1 4 datasets

Motif DE_36h DE_36h-Hic1_MA0739.2 8 bp overlap

Motif DE_48h DE_48h-Hic1_MA0739.2 8 bp overlap

Motif DE_60h DE_60h-Hic1_MA0739.2 8 bp overlap

Motif DE_72h DE_72h-Hic1_MA0739.2 8 bp overlap

Hnf1A 1 dataset

Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap

JUN::JUNB 1 dataset

Motif DE_60h DE_60h-JUNJUNB_MA1132.2 8 bp overlap

KDM1A 2 datasets

ChIP SU-DHL-4 GSE119038.KDM1A.SU-DHL-4 209 bp overlap

ChIP SU-DHL-4 GSE119038.KDM1A.SU-DHL-4 150 bp overlap

KMT2B 1 dataset

ChIP B-cell_GERMINAL_CENTER_TONSIL GSE67494.KMT2B.B-cell_GERMINAL_CENTER_TONSIL 92 bp overlap

Lef1 1 dataset

Motif DE_60h DE_60h-Lef1_MA0768.3 8 bp overlap

MAFK 1 dataset

ChIP OCI-Ly7 GSE47784.MAFK.OCI-Ly7 244 bp overlap

MED1 1 dataset

ChIP OCI-Ly1 GSE53601.MED1.OCI-Ly1 162 bp overlap

MEF2B 4 datasets

ChIP DLBCL GSE110682.MEF2B.DLBCL 236 bp overlap

ChIP DOHH2 GSE69558.MEF2B.DOHH2 99 bp overlap

ChIP GM12878 ENCSR177VFS.MEF2B.GM12878 247 bp overlap

ChIP tonsil GSE110682.MEF2B.tonsil 529 bp overlap

MEIS1 1 dataset

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

NANOG 2 datasets

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 484 bp overlap

ChIP hESC GSE18292.NANOG.hESC 121 bp overlap

NCOR2 1 dataset

ChIP B-cell_GERMINAL_CENTER GSE43350.NCOR2.B-cell_GERMINAL_CENTER 201 bp overlap

NR2F1 1 dataset

ChIP GM12878 ENCSR514VYD.NR2F1.GM12878 391 bp overlap

Nr1h3::Rxra 1 dataset

Motif DE_60h DE_60h-Nr1h3Rxra_MA0494.2 16 bp overlap

OTX1 1 dataset

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

OTX2 1 dataset

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 294 bp overlap

PAX5 1 dataset

ChIP OCI-Ly7 GSE69558.PAX5.OCI-Ly7 149 bp overlap

PHOX2A 1 dataset

Motif DE_60h DE_60h-PHOX2A_MA0713.1 11 bp overlap

PITX1 1 dataset

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

POLR2A 1 dataset

ChIP Raji ENCFF613VGX 338 bp overlap

PROP1 1 dataset

Motif DE_60h DE_60h-PROP1_MA0715.1 11 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap

Ptf1A 1 dataset

Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap

RBPJ 1 dataset

ChIP MUTUL GSE75503.RBPJ.MUTUL 244 bp overlap

RELA 1 dataset

ChIP BJAB GSE117250.RELA.BJAB 158 bp overlap

RHOXF1 1 dataset

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

Rhox11 1 dataset

Motif DE_60h DE_60h-Rhox11_MA0629.2 9 bp overlap

SIX1 1 dataset

Motif DE_60h DE_60h-SIX1_MA1118.2 9 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 557 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 178 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 260 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 325 bp overlap

SPIB 1 dataset

Motif DE_60h DE_60h-SPIB_MA0081.3 13 bp overlap

STAT1::STAT2 1 dataset

Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap

Sox11 1 dataset

Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap

Spi1 1 dataset

Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap

TCF7L1 1 dataset

Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 1 dataset

Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap

TERF1 1 dataset

ChIP LCL GSE55053.TERF1.LCL 186 bp overlap

TFAP2A 3 datasets

Motif DE_48h DE_48h-TFAP2A_MA0810.2 11 bp overlap

Motif DE_60h DE_60h-TFAP2A_MA0810.2 11 bp overlap

Motif DE_72h DE_72h-TFAP2A_MA0810.2 11 bp overlap

TFAP2B 3 datasets

Motif DE_48h DE_48h-TFAP2B_MA0811.2 11 bp overlap

Motif DE_60h DE_60h-TFAP2B_MA0811.2 11 bp overlap

Motif DE_72h DE_72h-TFAP2B_MA0811.2 11 bp overlap

THRA 1 dataset

Motif DE_60h DE_60h-THRA_MA1969.2 18 bp overlap

ZEB1 1 dataset

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

ZFP42 1 dataset

Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap

ZNF283 1 dataset

ChIP HEK293T GSE78099.ZNF283.HEK293T 157 bp overlap

ZNF382 1 dataset

Motif DE_60h DE_60h-ZNF382_MA1594.1 24 bp overlap