chr16 : 51,545,603 – 51,546,571
968 bp 67 TFs 3 linked genes
This 968 bp open chromatin element is linked to HNRNPA1L3, SALL1, and ENSG00000285367 and is bound by 67 transcription factors.
Linked Genes
3 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
HNRNPA1L3 6.9 kb Proximal Proximity
SALL1 393.9 kb Distal Multiome+HiCAR
ENSG00000285367 394.1 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr16:51,540,603 – 51,551,571
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
67 transcription factors
Source
Cell type
Atoh1 3 datasets
Motif DE_48h DE_48h-Atoh1_MA1467.3 7 bp overlap
Motif DE_60h DE_60h-Atoh1_MA1467.3 7 bp overlap
Motif DE_72h DE_72h-Atoh1_MA1467.3 7 bp overlap
BRD3 1 dataset
ChIP H-1_DE GSE126661.BRD3.H-1_DE 283 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF262VBH 520 bp overlap
EGR2 1 dataset
ChIP HEK293 ENCFF336LFH 343 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 525 bp overlap
ETS1 2 datasets
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 206 bp overlap
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 269 bp overlap
EWSR1-FLI1 3 datasets
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2 1 dataset
ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 356 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 884 bp overlap
ChIP DE DE-FOXA2-2 914 bp overlap
GATA2 2 datasets
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 205 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 340 bp overlap
GATA4 9 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 175 bp overlap
ChIP DE DE-GATA4-1 735 bp overlap
ChIP DE DE-GATA4-2 864 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 639 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 602 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 333 bp overlap
GATA5 3 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 17 datasets
ChIP DE DE-GATA6-1 689 bp overlap
ChIP DE DE-GATA6-2 819 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 639 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 687 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 780 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 717 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 771 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 785 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 613 bp overlap
ChIP foregut GSE117136.GATA6.foregut 546 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 629 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 455 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 536 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 357 bp overlap
GLI3 2 datasets
Motif DE_60h DE_60h-GLI3_MA1491.3 15 bp overlap
Motif DE_72h DE_72h-GLI3_MA1491.3 15 bp overlap
GLIS1 2 datasets
Motif DE_60h DE_60h-GLIS1_MA0735.2 15 bp overlap
Motif DE_72h DE_72h-GLIS1_MA0735.2 15 bp overlap
GLIS3 2 datasets
Motif DE_60h DE_60h-GLIS3_MA0737.1 14 bp overlap
Motif DE_72h DE_72h-GLIS3_MA0737.1 14 bp overlap
Gata3 3 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
Gli1 2 datasets
Motif DE_60h DE_60h-Gli1_MA1990.2 10 bp overlap
Motif DE_72h DE_72h-Gli1_MA1990.2 10 bp overlap
Gli2 2 datasets
Motif DE_60h DE_60h-Gli2_MA0734.4 9 bp overlap
Motif DE_72h DE_72h-Gli2_MA0734.4 9 bp overlap
HAND2 3 datasets
Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap
Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap
Motif DE_72h DE_72h-HAND2_MA1638.2 6 bp overlap
JUN 3 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 253 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 455 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 328 bp overlap
LMO2 1 dataset
ChIP Kasumi-1_SICTR GSE60130.LMO2.Kasumi-1_SICTR 177 bp overlap
MED1 1 dataset
ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 284 bp overlap
MITF 2 datasets
Motif DE_60h DE_60h-MITF_MA0620.4 10 bp overlap
Motif DE_72h DE_72h-MITF_MA0620.4 10 bp overlap
MSANTD3 6 datasets
Motif DE_36h DE_36h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_36h DE_36h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_60h DE_60h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_60h DE_60h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_72h DE_72h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_72h DE_72h-MSANTD3_MA1523.2 7 bp overlap
MXI1 2 datasets
Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap
Motif DE_72h DE_72h-MXI1_MA1108.3 6 bp overlap
MZF1 2 datasets
Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap
Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap
Msgn1 2 datasets
Motif DE_60h DE_60h-Msgn1_MA1524.3 10 bp overlap
Motif DE_72h DE_72h-Msgn1_MA1524.3 10 bp overlap
NEUROG2 3 datasets
Motif DE_48h DE_48h-NEUROG2_MA1642.2 7 bp overlap
Motif DE_60h DE_60h-NEUROG2_MA1642.2 7 bp overlap
Motif DE_72h DE_72h-NEUROG2_MA1642.2 7 bp overlap
NFATC3 6 datasets
Motif DE_36h DE_36h-NFATC3_MA0625.3 6 bp overlap
Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap
Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap
Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap
Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap
Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap
NFIX 3 datasets
Motif DE_48h DE_48h-NFIX_MA1528.2 14 bp overlap
Motif DE_60h DE_60h-NFIX_MA1528.2 14 bp overlap
Motif DE_72h DE_72h-NFIX_MA1528.2 14 bp overlap
NR1D2 3 datasets
Motif DE_36h DE_36h-NR1D2_MA1532.2 15 bp overlap
Motif DE_60h DE_60h-NR1D2_MA1532.2 15 bp overlap
Motif DE_72h DE_72h-NR1D2_MA1532.2 15 bp overlap
Nfat5 3 datasets
Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap
Motif DE_60h DE_60h-Nfat5_MA0606.3 8 bp overlap
Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap
Nfatc1 6 datasets
Motif DE_36h DE_36h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap
Nfatc2 3 datasets
Motif DE_48h DE_48h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_60h DE_60h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_72h DE_72h-Nfatc2_MA0152.3 8 bp overlap
Nkx2-1 3 datasets
Motif DE_36h DE_36h-Nkx2-1_MA1994.2 7 bp overlap
Motif DE_60h DE_60h-Nkx2-1_MA1994.2 7 bp overlap
Motif DE_72h DE_72h-Nkx2-1_MA1994.2 7 bp overlap
PDX1 1 dataset
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 309 bp overlap
PSIP1 1 dataset
ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 58 bp overlap
RBPJ 3 datasets
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap
RREB1 3 datasets
Motif DE_36h DE_36h-RREB1_MA0073.2 19 bp overlap
Motif DE_60h DE_60h-RREB1_MA0073.2 19 bp overlap
Motif DE_72h DE_72h-RREB1_MA0073.2 19 bp overlap
RXRB 2 datasets
Motif DE_60h DE_60h-RXRB_MA0855.1 14 bp overlap
Motif DE_72h DE_72h-RXRB_MA0855.1 14 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 143 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 614 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 634 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 485 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 321 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 459 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 517 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 488 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 197 bp overlap
SMARCA4 2 datasets
ChIP hiPSC GSE124903.SMARCA4.hiPSC 110 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 258 bp overlap
SMARCC1 3 datasets
ChIP TTC-549_Dox GSE71504.SMARCC1.TTC-549_Dox 579 bp overlap
ChIP TTC-549_NoDox GSE71504.SMARCC1.TTC-549_NoDox 619 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 183 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 369 bp overlap
SP5 5 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 265 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 183 bp overlap
TEAD1 3 datasets
Motif DE_36h DE_36h-TEAD1_MA0090.4 9 bp overlap
Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap
Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap
TEAD2 3 datasets
Motif DE_36h DE_36h-TEAD2_MA1121.2 7 bp overlap
Motif DE_60h DE_60h-TEAD2_MA1121.2 7 bp overlap
Motif DE_72h DE_72h-TEAD2_MA1121.2 7 bp overlap
TEAD3 3 datasets
Motif DE_36h DE_36h-TEAD3_MA0808.1 8 bp overlap
Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap
Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap
TEAD4 3 datasets
Motif DE_36h DE_36h-TEAD4_MA0809.3 8 bp overlap
Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap
Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap
TFEB 2 datasets
Motif DE_60h DE_60h-TFEB_MA0692.2 8 bp overlap
Motif DE_72h DE_72h-TFEB_MA0692.2 8 bp overlap
TRPS1 3 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
USF1 2 datasets
Motif DE_60h DE_60h-USF1_MA0093.4 10 bp overlap
Motif DE_72h DE_72h-USF1_MA0093.4 10 bp overlap
Wt1 2 datasets
Motif DE_60h DE_60h-Wt1_MA1627.2 10 bp overlap
Motif DE_72h DE_72h-Wt1_MA1627.2 10 bp overlap
ZBTB24 3 datasets
Motif DE_48h DE_48h-ZBTB24_MA2330.1 10 bp overlap
Motif DE_60h DE_60h-ZBTB24_MA2330.1 10 bp overlap
Motif DE_72h DE_72h-ZBTB24_MA2330.1 10 bp overlap
ZFHX2 1 dataset
ChIP HEK293 ENCFF167TUA 425 bp overlap
ZFP14 1 dataset
Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap
ZNF454 3 datasets
Motif DE_48h DE_48h-ZNF454_MA1712.2 17 bp overlap
Motif DE_60h DE_60h-ZNF454_MA1712.2 17 bp overlap
Motif DE_72h DE_72h-ZNF454_MA1712.2 17 bp overlap
ZNF530 3 datasets
Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap
Motif DE_60h DE_60h-ZNF530_MA1981.2 14 bp overlap
Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap
ZNF75A 2 datasets
Motif DE_60h DE_60h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_72h DE_72h-ZNF75A_MA2097.1 12 bp overlap
ZNF76 3 datasets
Motif DE_36h DE_36h-ZNF76_MA1716.2 17 bp overlap
Motif DE_60h DE_60h-ZNF76_MA1716.2 17 bp overlap
Motif DE_72h DE_72h-ZNF76_MA1716.2 17 bp overlap
ZSCAN29 3 datasets
Motif DE_36h DE_36h-ZSCAN29_MA1602.2 11 bp overlap
Motif DE_60h DE_60h-ZSCAN29_MA1602.2 11 bp overlap
Motif DE_72h DE_72h-ZSCAN29_MA1602.2 11 bp overlap
Zfp335 3 datasets
Motif DE_36h DE_36h-Zfp335_MA2002.2 7 bp overlap
Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap
Motif DE_72h DE_72h-Zfp335_MA2002.2 7 bp overlap
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