Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

53 transcription factors

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 376 bp overlap

ChIP K562 ENCFF938UXQ 169 bp overlap

BRD3 1 dataset

ChIP H-1_DE GSE126661.BRD3.H-1_DE 71 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 227 bp overlap

ChIP K562 ENCFF673OEZ 139 bp overlap

CBX2 1 dataset

ChIP K-562 ENCSR000ATU.CBX2.K-562 138 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 583 bp overlap

ETV5::FOXO1 1 dataset

Motif DE_72h DE_72h-ETV5FOXO1_MA1947.2 10 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 626 bp overlap

ChIP DE DE-FOXA2-2 758 bp overlap

FOXC2 1 dataset

Motif DE_72h DE_72h-FOXC2_MA0846.2 11 bp overlap

FOXK2 1 dataset

ChIP K-562 ENCSR302AWT.FOXK2.K-562 243 bp overlap

FOXP1 1 dataset

ChIP LNCaP GSE62492.FOXP1.LNCaP 106 bp overlap

Foxq1 1 dataset

Motif DE_72h DE_72h-Foxq1_MA0040.2 10 bp overlap

GATA1 4 datasets

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 110 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 136 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 236 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 342 bp overlap

GATA2 1 dataset

ChIP TF1 GSE73207.GATA2.TF1 576 bp overlap

GATA3 1 dataset

ChIP MCF-7_E2 GSE60270.GATA3.MCF-7_E2 140 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 716 bp overlap

ChIP DE DE-GATA4-2 762 bp overlap

ChIP foregut GSE117136.GATA4.foregut 605 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 369 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-1 708 bp overlap

ChIP DE DE-GATA6-2 801 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 755 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 361 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 685 bp overlap

ChIP foregut GSE117136.GATA6.foregut 581 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 392 bp overlap

HDAC2 1 dataset

ChIP RH4_DMSO-6H_bioMerck GSE116344.HDAC2.RH4_DMSO-6H_bioMerck 158 bp overlap

HLF 2 datasets

ChIP Hep-G2 ENCSR528PSI.HLF.Hep-G2 177 bp overlap

ChIP HepG2 ENCFF854JLR 245 bp overlap

HNF4A 4 datasets

ChIP Caco-2_PROLIF GSE23436.HNF4A.Caco-2_PROLIF 79 bp overlap

ChIP liver ENCFF354NRH 405 bp overlap

ChIP liver ENCFF449HPV 260 bp overlap

ChIP liver ERP002306.HNF4A.liver 194 bp overlap

HNF4G 1 dataset

ChIP liver ENCFF170YNZ 371 bp overlap

LDB1 1 dataset

ChIP K-562 GSE142227.LDB1.K-562 225 bp overlap

NCOA3 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 132 bp overlap

NCOR1 1 dataset

ChIP K-562 ENCSR798ILC.NCOR1.K-562 141 bp overlap

NFYB 1 dataset

Motif DE_72h DE_72h-NFYB_MA0502.3 9 bp overlap

NR5A1 1 dataset

Motif DE_72h DE_72h-NR5A1_MA1540.3 12 bp overlap

POU2F1 2 datasets

ChIP 22Rv1_DHT GSE123565.POU2F1.22Rv1_DHT 300 bp overlap

ChIP 22Rv1_Veh GSE123565.POU2F1.22Rv1_Veh 343 bp overlap

POU2F3 1 dataset

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 140 bp overlap

PRDM1 1 dataset

ChIP fetal_testis GSE100639.PRDM1.fetal_testis 159 bp overlap

PRDM9 1 dataset

Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap

Pgr 1 dataset

Motif DE_72h DE_72h-Pgr_MA2323.1 17 bp overlap

REST 2 datasets

ChIP LNCaP GSE119385.REST.LNCaP 220 bp overlap

ChIP LNCaP GSE119385.REST.LNCaP 454 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 630 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 595 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 753 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 220 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 513 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 598 bp overlap

SOX6 1 dataset

ChIP K-562 ENCSR788RSW.SOX6.K-562 287 bp overlap

SUZ12 1 dataset

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 314 bp overlap

Spz1 1 dataset

Motif DE_72h DE_72h-Spz1_MA0111.1 11 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 287 bp overlap

TAL1 8 datasets

ChIP CHRF28811 ERP008568.TAL1.CHRF28811 217 bp overlap

ChIP K-562 ENCSR106FRG.TAL1.K-562 199 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 316 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 205 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 182 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 179 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 196 bp overlap

ChIP K562 ENCFF620GMX 261 bp overlap

TCF12 2 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 197 bp overlap

ChIP K562 ENCFF931DJY 244 bp overlap

TRIM24 1 dataset

ChIP K-562 ENCSR907MZR.TRIM24.K-562 142 bp overlap

ZEB2 1 dataset

ChIP K-562 ENCSR004GKA.ZEB2.K-562 194 bp overlap

ZFP14 1 dataset

Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap

ZIC1 1 dataset

Motif DE_72h DE_72h-ZIC1_MA0696.1 14 bp overlap

ZIC4 1 dataset

Motif DE_72h DE_72h-ZIC4_MA0751.2 14 bp overlap

ZIC5 1 dataset

Motif DE_72h DE_72h-ZIC5_MA1584.2 15 bp overlap

ZNF16 1 dataset

Motif DE_72h DE_72h-ZNF16_MA1654.2 21 bp overlap

ZNF418 1 dataset

Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap

Zic1::Zic2 1 dataset

Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 1 dataset

Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap

Zic3 1 dataset

Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap

Gene	Dist. to TSS	Distance	Link type
NPC2	50.7 kb	Distal	Multiome
ISCA2	51.1 kb	Distal	Multiome
VRTN	94.2 kb	Distal	Multiome
ABCD4	139.7 kb	Distal	Multiome
AREL1	270.4 kb	Distal	Multiome
FCF1	270.5 kb	Distal	Multiome

Genome Browser