chr12 : 107,122,282 – 107,122,891
609 bp 88 TFs 3 linked genes
This 609 bp open chromatin element is linked to CRY1, MTERF2, and TMEM263 and is bound by 88 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
CRY1 29.1 kb Distal Multiome
MTERF2 135.5 kb Distal Multiome
TMEM263 166.8 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:107,117,282 – 107,127,891
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
88 transcription factors
Source
Cell type
BRD4 1 dataset
ChIP hESC GSE33281.BRD4.hESC 61 bp overlap
Bcl11B 1 dataset
Motif DE_48h DE_48h-Bcl11B_MA1989.2 9 bp overlap
ELF3 2 datasets
Motif DE_36h DE_36h-ELF3_MA0640.3 9 bp overlap
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 509 bp overlap
ERF::HOXB13 2 datasets
Motif DE_36h DE_36h-ERFHOXB13_MA1937.2 13 bp overlap
Motif DE_48h DE_48h-ERFHOXB13_MA1937.2 13 bp overlap
ESRRA 2 datasets
Motif DE_36h DE_36h-ESRRA_MA0592.4 9 bp overlap
Motif DE_48h DE_48h-ESRRA_MA0592.4 9 bp overlap
ESRRB 2 datasets
Motif DE_36h DE_36h-ESRRB_MA0141.4 10 bp overlap
Motif DE_48h DE_48h-ESRRB_MA0141.4 10 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 241 bp overlap
ETV5::DRGX 2 datasets
Motif DE_36h DE_36h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_48h DE_48h-ETV5DRGX_MA1944.2 12 bp overlap
ETV5::HOXA2 2 datasets
Motif DE_36h DE_36h-ETV5HOXA2_MA1948.2 12 bp overlap
Motif DE_48h DE_48h-ETV5HOXA2_MA1948.2 12 bp overlap
EWSR1-FLI1 2 datasets
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Esrrg 2 datasets
Motif DE_36h DE_36h-Esrrg_MA0643.2 9 bp overlap
Motif DE_48h DE_48h-Esrrg_MA0643.2 9 bp overlap
FLI1::DRGX 2 datasets
Motif DE_36h DE_36h-FLI1DRGX_MA1949.2 14 bp overlap
Motif DE_48h DE_48h-FLI1DRGX_MA1949.2 14 bp overlap
FOXA1 1 dataset
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 228 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 574 bp overlap
ChIP DE DE-FOXA2-2 533 bp overlap
FOXD2 2 datasets
Motif DE_36h DE_36h-FOXD2_MA0847.4 11 bp overlap
Motif DE_48h DE_48h-FOXD2_MA0847.4 11 bp overlap
FOXD3 2 datasets
Motif DE_36h DE_36h-FOXD3_MA0041.3 14 bp overlap
Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap
FOXE1 2 datasets
Motif DE_36h DE_36h-FOXE1_MA1487.3 12 bp overlap
Motif DE_48h DE_48h-FOXE1_MA1487.3 12 bp overlap
FOXO1::ELF1 2 datasets
Motif DE_36h DE_36h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::FLI1 2 datasets
Motif DE_36h DE_36h-FOXO1FLI1_MA1956.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1FLI1_MA1956.2 13 bp overlap
GATA1 2 datasets
Motif DE_36h DE_36h-GATA1_MA0035.5 7 bp overlap
Motif DE_48h DE_48h-GATA1_MA0035.5 7 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 572 bp overlap
ChIP DE DE-GATA4-2 609 bp overlap
ChIP foregut GSE117136.GATA4.foregut 559 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 609 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 394 bp overlap
GATA6 14 datasets
ChIP DE DE-GATA6-1 536 bp overlap
ChIP DE DE-GATA6-2 575 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 585 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 609 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 562 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 526 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 609 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 582 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 516 bp overlap
ChIP foregut GSE117136.GATA6.foregut 548 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 258 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 540 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 419 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 323 bp overlap
HOXD12::ELK1 2 datasets
Motif DE_36h DE_36h-HOXD12ELK1_MA1958.2 13 bp overlap
Motif DE_48h DE_48h-HOXD12ELK1_MA1958.2 13 bp overlap
IKZF1 1 dataset
Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap
IKZF2 2 datasets
Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
JUN 5 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 272 bp overlap
ChIP DE_D1 S13-DE-d1-JUN-exp1 264 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 286 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 348 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 337 bp overlap
KLF1 2 datasets
Motif DE_36h DE_36h-KLF1_MA0493.3 8 bp overlap
Motif DE_48h DE_48h-KLF1_MA0493.3 8 bp overlap
KLF10 2 datasets
Motif DE_36h DE_36h-KLF10_MA1511.2 9 bp overlap
Motif DE_48h DE_48h-KLF10_MA1511.2 9 bp overlap
KLF11 2 datasets
Motif DE_36h DE_36h-KLF11_MA1512.2 10 bp overlap
Motif DE_48h DE_48h-KLF11_MA1512.2 10 bp overlap
KLF14 2 datasets
Motif DE_36h DE_36h-KLF14_MA0740.2 9 bp overlap
Motif DE_48h DE_48h-KLF14_MA0740.2 9 bp overlap
KLF16 2 datasets
Motif DE_36h DE_36h-KLF16_MA0741.1 11 bp overlap
Motif DE_48h DE_48h-KLF16_MA0741.1 11 bp overlap
KLF2 2 datasets
Motif DE_36h DE_36h-KLF2_MA1515.2 8 bp overlap
Motif DE_48h DE_48h-KLF2_MA1515.2 8 bp overlap
KLF4 3 datasets
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 165 bp overlap
Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap
Motif DE_48h DE_48h-KLF4_MA0039.5 8 bp overlap
KLF5 2 datasets
Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
KLF9 2 datasets
Motif DE_36h DE_36h-KLF9_MA1107.3 11 bp overlap
Motif DE_48h DE_48h-KLF9_MA1107.3 11 bp overlap
NANOG 5 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 366 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 221 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 370 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 337 bp overlap
ChIP hESC GSE18292.NANOG.hESC 93 bp overlap
NFATC3 2 datasets
Motif DE_36h DE_36h-NFATC3_MA0625.3 6 bp overlap
Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap
NFATC4 2 datasets
Motif DE_36h DE_36h-NFATC4_MA1525.3 9 bp overlap
Motif DE_48h DE_48h-NFATC4_MA1525.3 9 bp overlap
NR6A1 2 datasets
Motif DE_36h DE_36h-NR6A1_MA1541.2 14 bp overlap
Motif DE_48h DE_48h-NR6A1_MA1541.2 14 bp overlap
Nfatc1 2 datasets
Motif DE_36h DE_36h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap
Nfatc2 2 datasets
Motif DE_36h DE_36h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_48h DE_48h-Nfatc2_MA0152.3 8 bp overlap
Nr5A2 2 datasets
Motif DE_36h DE_36h-Nr5A2_MA0505.3 9 bp overlap
Motif DE_48h DE_48h-Nr5A2_MA0505.3 9 bp overlap
PATZ1 2 datasets
Motif DE_36h DE_36h-PATZ1_MA1961.2 11 bp overlap
Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap
PDX1 2 datasets
ChIP hiPSC GSE125768.PDX1.hiPSC 509 bp overlap
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 271 bp overlap
POU1F1 2 datasets
Motif DE_36h DE_36h-POU1F1_MA0784.3 14 bp overlap
Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap
POU2F1::SOX2 1 dataset
Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F2 2 datasets
Motif DE_36h DE_36h-POU2F2_MA0507.3 13 bp overlap
Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap
POU3F2 2 datasets
Motif DE_36h DE_36h-POU3F2_MA0787.1 12 bp overlap
Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap
POU3F3 2 datasets
Motif DE_36h DE_36h-POU3F3_MA0788.1 13 bp overlap
Motif DE_48h DE_48h-POU3F3_MA0788.1 13 bp overlap
POU5F1 3 datasets
ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 115 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 398 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 332 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 339 bp overlap
PRDM9 2 datasets
Motif DE_36h DE_36h-PRDM9_MA1723.2 20 bp overlap
Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap
Pou5f1::Sox2 2 datasets
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
REST 2 datasets
ChIP H1 ENCFF429RUE 199 bp overlap
ChIP WA01 ENCSR000BHM.REST.WA01 143 bp overlap
RREB1 2 datasets
Motif DE_36h DE_36h-RREB1_MA0073.2 19 bp overlap
Motif DE_48h DE_48h-RREB1_MA0073.2 19 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 509 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 489 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 457 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 469 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 394 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 282 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 433 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 490 bp overlap
SMAD3 1 dataset
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 212 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 244 bp overlap
SMARCA4 2 datasets
ChIP hiPSC GSE124903.SMARCA4.hiPSC 339 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 371 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 254 bp overlap
SMARCC1 2 datasets
ChIP G-401_NoDox GSE71504.SMARCC1.G-401_NoDox 196 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 309 bp overlap
SOX10 1 dataset
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 443 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 505 bp overlap
SOX2 1 dataset
ChIP hiPSC GSE56567.SOX2.hiPSC 241 bp overlap
SP8 2 datasets
Motif DE_36h DE_36h-SP8_MA0747.2 11 bp overlap
Motif DE_48h DE_48h-SP8_MA0747.2 11 bp overlap
SP9 2 datasets
Motif DE_36h DE_36h-SP9_MA1564.2 10 bp overlap
Motif DE_48h DE_48h-SP9_MA1564.2 10 bp overlap
SPIC 2 datasets
Motif DE_36h DE_36h-SPIC_MA0687.2 13 bp overlap
Motif DE_48h DE_48h-SPIC_MA0687.2 13 bp overlap
Spi1 2 datasets
Motif DE_36h DE_36h-Spi1_MA0080.7 13 bp overlap
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 324 bp overlap
TEAD1 2 datasets
Motif DE_48h DE_48h-TEAD1_MA0090.4 9 bp overlap
ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 154 bp overlap
TEAD2 1 dataset
Motif DE_48h DE_48h-TEAD2_MA1121.2 7 bp overlap
TEAD3 1 dataset
Motif DE_48h DE_48h-TEAD3_MA0808.1 8 bp overlap
TEAD4 1 dataset
Motif DE_48h DE_48h-TEAD4_MA0809.3 8 bp overlap
Wt1 2 datasets
Motif DE_36h DE_36h-Wt1_MA1627.2 10 bp overlap
Motif DE_48h DE_48h-Wt1_MA1627.2 10 bp overlap
ZNF136 1 dataset
Motif DE_48h DE_48h-ZNF136_MA1588.1 15 bp overlap
ZNF148 2 datasets
Motif DE_36h DE_36h-ZNF148_MA1653.2 10 bp overlap
Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap
ZNF214 1 dataset
Motif DE_48h DE_48h-ZNF214_MA1975.2 13 bp overlap
ZNF281 2 datasets
Motif DE_36h DE_36h-ZNF281_MA1630.3 10 bp overlap
Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap
ZNF354C 2 datasets
Motif DE_36h DE_36h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_48h DE_48h-ZNF354C_MA0130.1 6 bp overlap
ZNF410 2 datasets
Motif DE_36h DE_36h-ZNF410_MA0752.2 16 bp overlap
Motif DE_48h DE_48h-ZNF410_MA0752.2 16 bp overlap
ZNF547 1 dataset
Motif DE_48h DE_48h-ZNF547_MA2334.1 13 bp overlap
ZNF684 2 datasets
Motif DE_36h DE_36h-ZNF684_MA1600.2 14 bp overlap
Motif DE_48h DE_48h-ZNF684_MA1600.2 14 bp overlap
ZNF707 1 dataset
Motif DE_48h DE_48h-ZNF707_MA1715.1 15 bp overlap
ZNF740 2 datasets
Motif DE_36h DE_36h-ZNF740_MA0753.3 10 bp overlap
Motif DE_48h DE_48h-ZNF740_MA0753.3 10 bp overlap
ZNF823 1 dataset
ChIP HEK293T GSE78099.ZNF823.HEK293T 223 bp overlap
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