chr12 : 93,370,990 – 93,371,306

316 bp 67 TFs 2 linked genes

This 316 bp open chromatin element is linked to ENSG00000257252 and NUDT4 and is bound by 67 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000257252		6.4 kb	Proximal	Proximity
NUDT4		6.6 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

67 transcription factors

BRD2 2 datasets

ChIP K-562_DMSO GSE138084.BRD2.K-562_DMSO 202 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD2.K-562_iBET-IFNG 316 bp overlap

BRD3 2 datasets

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 316 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 148 bp overlap

BRD4 3 datasets

ChIP K-562_DMSO GSE138084.BRD4.K-562_DMSO 260 bp overlap

ChIP K-562_iBET-BD2 GSE138084.BRD4.K-562_iBET-BD2 241 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 207 bp overlap

CC2D1A 1 dataset

ChIP K562 ENCFF567XUT 56 bp overlap

CTCF 2 datasets

ChIP endodermal cell ENCFF471YCZ 316 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 237 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF364PUR 66 bp overlap

EBF1 1 dataset

Motif ES_0h ES_0h-EBF1_MA0154.5 11 bp overlap

ETV2::HOXB13 1 dataset

Motif DE_12h DE_12h-ETV2HOXB13_MA1943.2 13 bp overlap

Ebf4 1 dataset

Motif ES_0h ES_0h-Ebf4_MA2122.1 11 bp overlap

FOXA1 1 dataset

Motif ES_0h ES_0h-FOXA1_MA0148.5 8 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 262 bp overlap

Motif ES_0h ES_0h-FOXA2_MA0047.4 8 bp overlap

FOXA3 1 dataset

Motif ES_0h ES_0h-FOXA3_MA1683.2 7 bp overlap

FOXD1 1 dataset

Motif ES_0h ES_0h-FOXD1_MA0031.2 7 bp overlap

FOXF2 1 dataset

Motif ES_0h ES_0h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif ES_0h ES_0h-FOXG1_MA0613.1 8 bp overlap

FOXI1 1 dataset

Motif ES_0h ES_0h-FOXI1_MA0042.2 7 bp overlap

FOXK1 1 dataset

Motif ES_0h ES_0h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif ES_0h ES_0h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif ES_0h ES_0h-FOXL1_MA0033.2 7 bp overlap

FOXO1::ELK3 1 dataset

Motif DE_12h DE_12h-FOXO1ELK3_MA1955.2 13 bp overlap

FOXO1::FLI1 1 dataset

Motif DE_12h DE_12h-FOXO1FLI1_MA1956.2 13 bp overlap

FOXO4 1 dataset

Motif ES_0h ES_0h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif ES_0h ES_0h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

Motif ES_0h ES_0h-FOXP1_MA0481.4 7 bp overlap

FOXP3 1 dataset

Motif ES_0h ES_0h-FOXP3_MA0850.1 7 bp overlap

FOXP4 1 dataset

Motif ES_0h ES_0h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif ES_0h ES_0h-FOXS1_MA2118.1 8 bp overlap

Foxf1 1 dataset

Motif ES_0h ES_0h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif ES_0h ES_0h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif ES_0h ES_0h-Foxj3_MA0851.2 9 bp overlap

Foxl2 1 dataset

Motif ES_0h ES_0h-Foxl2_MA1607.2 10 bp overlap

Foxo1 1 dataset

Motif ES_0h ES_0h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif ES_0h ES_0h-Foxo3_MA0157.4 7 bp overlap

HDGF 1 dataset

ChIP K-562 ENCSR197ALX.HDGF.K-562 193 bp overlap

HNF4A 1 dataset

ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 159 bp overlap

HSF1 1 dataset

Motif ES_0h ES_0h-HSF1_MA0486.2 13 bp overlap

HSF2 1 dataset

Motif ES_0h ES_0h-HSF2_MA0770.1 13 bp overlap

HSF4 1 dataset

Motif ES_0h ES_0h-HSF4_MA0771.1 13 bp overlap

ID3 1 dataset

ChIP K-562 ENCSR005NMT.ID3.K-562 174 bp overlap

IRF1 1 dataset

ChIP HAEC_IL1b_4h GSE89970.IRF1.HAEC_IL1b_4h 139 bp overlap

IRF2 1 dataset

Motif DE_12h DE_12h-IRF2_MA0051.2 16 bp overlap

IRF4 1 dataset

Motif DE_12h DE_12h-IRF4_MA1419.2 14 bp overlap

IRF7 1 dataset

Motif DE_12h DE_12h-IRF7_MA0772.2 13 bp overlap

IRF8 1 dataset

Motif DE_12h DE_12h-IRF8_MA0652.2 13 bp overlap

IRF9 1 dataset

Motif DE_12h DE_12h-IRF9_MA0653.1 15 bp overlap

Irf1 1 dataset

Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap

KLF4 3 datasets

ChIP WA09 GSE105028.KLF4.WA09 282 bp overlap

ChIP WA09_heat-shock GSE105028.KLF4.WA09_heat-shock 237 bp overlap

ChIP WIBR3 GSE130417.KLF4.WIBR3 140 bp overlap

MYOD1 1 dataset

ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 147 bp overlap

NANOG 3 datasets

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 316 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 316 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 316 bp overlap

NR2C1 1 dataset

ChIP K-562 ENCSR178DEG.NR2C1.K-562 187 bp overlap

NSD2 1 dataset

ChIP K562 ENCFF571LTZ 197 bp overlap

POU5F1 1 dataset

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 316 bp overlap

PRDM14 1 dataset

ChIP primordial-germ-cell-like-cell GSE138674.PRDM14.primordial-germ-cell-like-cell 214 bp overlap

RUNX3 1 dataset

Motif DE_12h DE_12h-RUNX3_MA0684.3 8 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 316 bp overlap

STAT1::STAT2 1 dataset

Motif DE_12h DE_12h-STAT1STAT2_MA0517.2 13 bp overlap

Stat2 1 dataset

Motif DE_12h DE_12h-Stat2_MA1623.2 10 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 316 bp overlap

TEAD3 1 dataset

Motif ES_0h ES_0h-TEAD3_MA0808.1 8 bp overlap

TEAD4 2 datasets

ChIP H1 ENCFF778PAX 245 bp overlap

ChIP SNU-216 GSE44416.TEAD4.SNU-216 316 bp overlap

TFAP2A 1 dataset

ChIP WA09 GSE105081.TFAP2A.WA09 238 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 274 bp overlap

ZBTB7B 1 dataset

ChIP Hep-G2 ENCSR322ULL.ZBTB7B.Hep-G2 160 bp overlap

ZIM3 1 dataset

Motif DE_12h DE_12h-ZIM3_MA1709.2 11 bp overlap

ZNF215 3 datasets

ChIP K-562 ENCSR699RWG.ZNF215.K-562 140 bp overlap

ChIP K562 ENCFF317MOH 281 bp overlap

ChIP K562 ENCFF317MOH 73 bp overlap

ZNF281 2 datasets

Motif ES_0h ES_0h-ZNF281_MA1630.3 10 bp overlap

ChIP K562 ENCFF594VNM 54 bp overlap

ZNF592 2 datasets

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 277 bp overlap

ChIP K562 ENCFF547OSS 124 bp overlap