chr11 : 43,269,226 – 43,269,681

455 bp 80 TFs 1 linked gene

This 455 bp open chromatin element is linked to HNRNPKP3 and is bound by 80 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
HNRNPKP3		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

80 transcription factors

AR 1 dataset

ChIP MCF-7 GSE48930.AR.MCF-7 182 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 417 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 249 bp overlap

ATRX 1 dataset

ChIP metastatic-neuroblastoma_SKNFI GSE100148.ATRX.metastatic-neuroblastoma_SKNFI 455 bp overlap

Atoh1 1 dataset

Motif DE_12h DE_12h-Atoh1_MA1467.3 7 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 232 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 285 bp overlap

BRD4 4 datasets

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 455 bp overlap

ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 133 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 331 bp overlap

ChIP hESC GSE33281.BRD4.hESC 102 bp overlap

CTCF 5 datasets

ChIP 22Rv1 ENCFF466OXN 70 bp overlap

ChIP 22Rv1 ENCFF466OXN 275 bp overlap

ChIP C4-2B ENCFF821XVN 191 bp overlap

ChIP GSC23 GSE139416.CTCF.GSC23 155 bp overlap

ChIP WA01_NEUR GSE52457.CTCF.WA01_NEUR 138 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 126 bp overlap

EGR1 1 dataset

ChIP H1 ENCFF451BLH 223 bp overlap

ELF2 1 dataset

Motif DE_12h DE_12h-ELF2_MA1483.3 10 bp overlap

ELK1 1 dataset

Motif DE_12h DE_12h-ELK1_MA0028.3 9 bp overlap

ERF 1 dataset

Motif DE_12h DE_12h-ERF_MA0760.2 9 bp overlap

ERF::FOXI1 1 dataset

Motif DE_12h DE_12h-ERFFOXI1_MA1935.2 10 bp overlap

ERF::NHLH1 1 dataset

Motif DE_12h DE_12h-ERFNHLH1_MA1938.2 16 bp overlap

ERG 2 datasets

ChIP ME-1 GSE46044.ERG.ME-1 200 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 286 bp overlap

ETS1 2 datasets

Motif DE_12h DE_12h-ETS1_MA0098.4 9 bp overlap

ChIP THP-6_shCtrl GSE138516.ETS1.THP-6_shCtrl 275 bp overlap

ETS2 1 dataset

Motif DE_12h DE_12h-ETS2_MA1484.2 9 bp overlap

ETV1 1 dataset

Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap

ETV2 1 dataset

Motif DE_12h DE_12h-ETV2_MA0762.2 9 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap

ETV3 1 dataset

Motif DE_12h DE_12h-ETV3_MA0763.2 9 bp overlap

ETV4 1 dataset

Motif DE_12h DE_12h-ETV4_MA0764.4 9 bp overlap

EZH2_phosphoT487 1 dataset

ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 410 bp overlap

Elf5 1 dataset

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

Erg 1 dataset

Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap

FEV 1 dataset

Motif DE_12h DE_12h-FEV_MA0156.4 9 bp overlap

FLI1 6 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 355 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 278 bp overlap

ChIP A-673_D14 GSE129155.FLI1.A-673_D14 208 bp overlap

ChIP A-673_D17 GSE129155.FLI1.A-673_D17 293 bp overlap

Motif DE_12h DE_12h-FLI1_MA0475.3 9 bp overlap

ChIP SKNO-1 GSE23730.FLI1.SKNO-1 355 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_12h DE_12h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 283 bp overlap

FOXJ2::ELF1 1 dataset

Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_12h DE_12h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::ELK3 1 dataset

Motif DE_12h DE_12h-FOXO1ELK3_MA1955.2 13 bp overlap

FOXO1::FLI1 1 dataset

Motif DE_12h DE_12h-FOXO1FLI1_MA1956.2 13 bp overlap

Foxn1 1 dataset

Motif DE_12h DE_12h-Foxn1_MA1684.1 6 bp overlap

GABPA 1 dataset

Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap

GATA2 1 dataset

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 242 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 196 bp overlap

HAND2 4 datasets

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 394 bp overlap

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 190 bp overlap

IKZF1 1 dataset

Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

ISL1 1 dataset

ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 361 bp overlap

KDM1A 2 datasets

ChIP SH-SY5Y_B0 GSE58258.KDM1A.SH-SY5Y_B0 353 bp overlap

ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 168 bp overlap

KDM4C 1 dataset

ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 194 bp overlap

MRTFB 1 dataset

ChIP A-673-clone-Asp114 GSE92738.MRTFB.A-673-clone-Asp114 214 bp overlap

MYC 1 dataset

ChIP CD34 GSE85488.MYC.CD34 153 bp overlap

MYCN 4 datasets

ChIP CHP-134 GSE129588.MYCN.CHP-134 408 bp overlap

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 455 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 242 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 455 bp overlap

NEUROD1 2 datasets

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 380 bp overlap

Motif DE_12h DE_12h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 6 datasets

Motif DE_12h DE_12h-NEUROG2_MA1642.2 7 bp overlap

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 262 bp overlap

ChIP MRC-5_NFD_05DPT GSE75910.NEUROG2.MRC-5_NFD_05DPT 261 bp overlap

ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 285 bp overlap

ChIP MRC-5_N_02DPT GSE75910.NEUROG2.MRC-5_N_02DPT 247 bp overlap

ChIP MRC-5_N_1DPT GSE75910.NEUROG2.MRC-5_N_1DPT 226 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA0668.3 8 bp overlap

PHOX2B 1 dataset

ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 403 bp overlap

PITX3 1 dataset

ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 455 bp overlap

POLR2A 1 dataset

ChIP spleen ENCFF446ZGT 290 bp overlap

POU5F1 1 dataset

ChIP BG03 GSE21614.POU5F1.BG03 215 bp overlap

RAD21 1 dataset

ChIP IMR-5 GSE78957.RAD21.IMR-5 136 bp overlap

REST 3 datasets

ChIP hippocampus GSE144226.REST.hippocampus 313 bp overlap

ChIP neural ENCSR000BTV.REST.neural 79 bp overlap

ChIP neural cell ENCFF882LXX 268 bp overlap

RUNX1 2 datasets

ChIP Jurkat GSE85524.RUNX1.Jurkat 217 bp overlap

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 293 bp overlap

Rarb 1 dataset

Motif DE_12h DE_12h-Rarb_MA0858.1 17 bp overlap

Runx1 2 datasets

Motif DE_12h DE_12h-Runx1_MA0002.3 9 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 168 bp overlap

SMAD1 1 dataset

ChIP BG03 GSE36578.SMAD1.BG03 96 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 209 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

TBP 1 dataset

ChIP hiPSC_WTa_RNase-neg GSE128135.TBP.hiPSC_WTa_RNase-neg 200 bp overlap

TEAD4 2 datasets

ChIP BE2C GSE84389.TEAD4.BE2C 382 bp overlap

ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 382 bp overlap

TET2 1 dataset

ChIP Jurkat_RUNX1KD GSE85524.TET2.Jurkat_RUNX1KD 209 bp overlap

TSHZ2 1 dataset

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR282NLQ.TSHZ2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 264 bp overlap

USF1 1 dataset

ChIP SK-N-SH ENCSR000BMF.USF1.SK-N-SH 152 bp overlap

YY1 1 dataset

ChIP SK-N-SH ENCSR000BLZ.YY1.SK-N-SH 141 bp overlap

ZNF175 1 dataset

Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap

ZNF263 1 dataset

ChIP Hep-G2 ENCSR313MMD.ZNF263.Hep-G2 123 bp overlap

ZNF418 1 dataset

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap

ZNF528 1 dataset

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

ZNF768 1 dataset

Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap

ZNF93 1 dataset

Motif DE_12h DE_12h-ZNF93_MA1721.2 14 bp overlap

Zbtb2 1 dataset

Motif DE_12h DE_12h-Zbtb2_MA2340.1 10 bp overlap

Zic1::Zic2 1 dataset

Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 2 datasets

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap

Zic3 1 dataset

Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap