chr10 : 22,705,948 – 22,706,483

535 bp 86 TFs 1 linked gene

This 535 bp open chromatin element is linked to PIP4K2A and is bound by 86 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
PIP4K2A		8.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

86 transcription factors

AR 1 dataset

ChIP VCaP_Veh GSE125245.AR.VCaP_Veh 117 bp overlap

ATF2 3 datasets

ChIP Hep-G2 ENCSR047BUZ.ATF2.Hep-G2 99 bp overlap

ChIP K-562 ENCSR869IUD.ATF2.K-562 134 bp overlap

ChIP K562 ENCFF139ZZG 199 bp overlap

BHLHE22 1 dataset

Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap

BRD3 1 dataset

ChIP MV4-11_DMSO GSE120715.BRD3.MV4-11_DMSO 218 bp overlap

BRD4 1 dataset

ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 210 bp overlap

CC2D1A 2 datasets

ChIP K-562 ENCSR343IFJ.CC2D1A.K-562 397 bp overlap

ChIP K562 ENCFF567XUT 445 bp overlap

CDK6 1 dataset

ChIP KB_IL GSE52469.CDK6.KB_IL 88 bp overlap

CHAMP1 3 datasets

ChIP K-562 ENCSR065XVO.CHAMP1.K-562 485 bp overlap

ChIP K562 ENCFF860ZIW 320 bp overlap

ChIP K562 ENCFF860ZIW 444 bp overlap

Crx 1 dataset

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

DACH1 1 dataset

ChIP K-562 ENCSR030TJP.DACH1.K-562 231 bp overlap

DUX4 1 dataset

ChIP WA01 GSE94322.DUX4.WA01 270 bp overlap

Dmbx1 1 dataset

Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap

EGR1 3 datasets

ChIP K-562 ENCSR000BNE.EGR1.K-562 104 bp overlap

ChIP K-562 ENCSR211LTF.EGR1.K-562 234 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 238 bp overlap

ESR1_pS118 1 dataset

ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 176 bp overlap

ESRRB 1 dataset

Motif DE_60h DE_60h-ESRRB_MA0141.4 10 bp overlap

ETV5::DRGX 1 dataset

Motif DE_60h DE_60h-ETV5DRGX_MA1944.2 12 bp overlap

FIP1L1 1 dataset

ChIP Hep-G2 ENCSR313VZG.FIP1L1.Hep-G2 86 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 520 bp overlap

ChIP DE DE-FOXA2-2 377 bp overlap

ChIP PANC-1_HNF1B-OE GSE119930.FOXA2.PANC-1_HNF1B-OE 96 bp overlap

GATA1 2 datasets

ChIP K-562 GSE107726.GATA1.K-562 164 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 164 bp overlap

GATA2 1 dataset

ChIP K562 ENCFF544PCK 251 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 530 bp overlap

ChIP DE DE-GATA4-2 483 bp overlap

ChIP foregut GSE117136.GATA4.foregut 353 bp overlap

GATA6 6 datasets

ChIP AGS GSE51936.GATA6.AGS 95 bp overlap

ChIP DE DE-GATA6-1 535 bp overlap

ChIP DE DE-GATA6-2 497 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 425 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 421 bp overlap

ChIP foregut GSE117136.GATA6.foregut 378 bp overlap

GSC 1 dataset

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

HDGF 1 dataset

ChIP K-562 ENCSR563YDA.HDGF.K-562 219 bp overlap

HMBOX1 2 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 165 bp overlap

ChIP K562 ENCFF317JJX 401 bp overlap

HNF4A 1 dataset

ChIP Hep-G2 ENCSR000BLF.HNF4A.Hep-G2 123 bp overlap

HOXB2::ELK1 1 dataset

Motif DE_60h DE_60h-HOXB2ELK1_MA1957.1 14 bp overlap

MLLT1 2 datasets

ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 146 bp overlap

ChIP K-562 ENCSR107GRP.MLLT1.K-562 78 bp overlap

MNX1 1 dataset

ChIP Hep-G2 ENCSR108MKR.MNX1.Hep-G2 156 bp overlap

MYOG 1 dataset

Motif DE_60h DE_60h-MYOG_MA0500.3 8 bp overlap

NEUROD1 1 dataset

ChIP D283-Med GSE92582.NEUROD1.D283-Med 331 bp overlap

NFIA 1 dataset

Motif DE_60h DE_60h-NFIA_MA0670.2 6 bp overlap

NFIC 1 dataset

Motif DE_60h DE_60h-NFIC_MA0161.3 7 bp overlap

NFIX 1 dataset

Motif DE_60h DE_60h-NFIX_MA0671.2 6 bp overlap

NHLH1 1 dataset

Motif DE_60h DE_60h-NHLH1_MA0048.3 9 bp overlap

NR3C1 1 dataset

ChIP A-549 ENCSR000BJR.NR3C1.A-549 165 bp overlap

Neurod2 1 dataset

Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap

Nr5A2 1 dataset

Motif DE_60h DE_60h-Nr5A2_MA0505.3 9 bp overlap

OTX1 1 dataset

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

Olig2 1 dataset

Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap

PITX1 1 dataset

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

POLR2A 1 dataset

ChIP GM12892 ENCFF245LYF 366 bp overlap

PRDM9 1 dataset

Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap

RBFOX2 2 datasets

ChIP K-562 GSE120104.RBFOX2.K-562 120 bp overlap

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 84 bp overlap

RELA 1 dataset

ChIP KB_IL GSE52469.RELA.KB_IL 111 bp overlap

REST 1 dataset

ChIP PANC-1 ENCSR000BJO.REST.PANC-1 82 bp overlap

RFX1 1 dataset

ChIP Hep-G2 ENCSR928API.RFX1.Hep-G2 252 bp overlap

RHOXF1 1 dataset

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 395 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 167 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 487 bp overlap

SOX18 1 dataset

Motif DE_60h DE_60h-SOX18_MA1563.2 8 bp overlap

SOX4 1 dataset

Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap

SOX8 1 dataset

Motif DE_60h DE_60h-SOX8_MA0868.3 7 bp overlap

SOX9 1 dataset

Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap

SRY 1 dataset

Motif DE_60h DE_60h-SRY_MA0084.2 7 bp overlap

Sox17 1 dataset

Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap

Sox5 1 dataset

Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap

TARDBP 1 dataset

ChIP GM12878 ENCSR412QBS.TARDBP.GM12878 52 bp overlap

TBR1 1 dataset

Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap

TBX21 1 dataset

Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap

TFAP2E 1 dataset

Motif DE_60h DE_60h-TFAP2E_MA1569.2 9 bp overlap

TFAP4 2 datasets

ChIP K562 ENCFF727PXG 336 bp overlap

ChIP K562 ENCFF727PXG 135 bp overlap

TRIM24 3 datasets

ChIP K-562 ENCSR907MZR.TRIM24.K-562 228 bp overlap

ChIP MOLM-13_IACS-9571 GSE100571.TRIM24.MOLM-13_IACS-9571 202 bp overlap

ChIP MOLM-13_dTRIM24 GSE100571.TRIM24.MOLM-13_dTRIM24 138 bp overlap

Tcf12 1 dataset

Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap

ZBTB33 5 datasets

ChIP GM12878 ENCFF818EFA 201 bp overlap

ChIP GM12878 ENCSR542FLV.ZBTB33.GM12878 214 bp overlap

ChIP HepG2 ENCFF778UKV 241 bp overlap

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 344 bp overlap

ChIP K562 ENCFF875HLX 106 bp overlap

ZBTB38 1 dataset

ChIP HepG2 ENCFF875UQX 293 bp overlap

ZFP14 1 dataset

Motif DE_60h DE_60h-ZFP14_MA1972.1 15 bp overlap

ZMYM3 1 dataset

ChIP Hep-G2_Ab_JH39-2-2F10 GSE97661.ZMYM3.Hep-G2_Ab_JH39-2-2F10 136 bp overlap

ZNF143 4 datasets

ChIP CUTLL1 GSE29600.ZNF143.CUTLL1 167 bp overlap

ChIP K-562 GSE39263.ZNF143.K-562 203 bp overlap

ChIP MCF-7 GSE76454.ZNF143.MCF-7 366 bp overlap

ChIP MCF-7_E2 GSE76454.ZNF143.MCF-7_E2 290 bp overlap

ZNF213 1 dataset

Motif DE_60h DE_60h-ZNF213_MA2121.1 12 bp overlap

ZNF214 1 dataset

Motif DE_60h DE_60h-ZNF214_MA1975.2 13 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 154 bp overlap

ZNF675 1 dataset

Motif DE_60h DE_60h-ZNF675_MA1714.2 19 bp overlap

ZNF684 1 dataset

Motif DE_60h DE_60h-ZNF684_MA1600.2 14 bp overlap

ZNF701 1 dataset

Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap

ZNF736 1 dataset

ChIP HEK293T GSE78099.ZNF736.HEK293T 99 bp overlap

ZNF816 1 dataset

Motif DE_60h DE_60h-ZNF816_MA1719.2 15 bp overlap

ZNF85 1 dataset

Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap

Zic2 1 dataset

Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap