chr8 : 51,553,857 – 51,554,935
1,078 bp 76 TFs 1 linked gene
This 1.1 kb open chromatin element is linked to PXDNL and is bound by 76 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PXDNL 255.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:51,548,857 – 51,559,935
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
76 transcription factors
Source
Cell type
ASCL1 3 datasets
Motif DE_36h DE_36h-ASCL1_MA1631.2 9 bp overlap
Motif DE_48h DE_48h-ASCL1_MA1631.2 9 bp overlap
Motif DE_60h DE_60h-ASCL1_MA1631.2 9 bp overlap
BRD4 1 dataset
ChIP MV4-11_IBET151_5000nM GSE120715.BRD4.MV4-11_IBET151_5000nM 191 bp overlap
CHD7 1 dataset
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 518 bp overlap
CTCF 4 datasets
Motif DE_36h DE_36h-CTCF_MA0139.2 15 bp overlap
Motif DE_48h DE_48h-CTCF_MA0139.2 15 bp overlap
Motif DE_60h DE_60h-CTCF_MA0139.2 15 bp overlap
ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 253 bp overlap
Crx 3 datasets
Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
DPRX 3 datasets
Motif DE_36h DE_36h-DPRX_MA1480.2 9 bp overlap
Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap
Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap
Dmbx1 3 datasets
Motif DE_36h DE_36h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap
E2F7 3 datasets
Motif DE_36h DE_36h-E2F7_MA0758.1 14 bp overlap
Motif DE_48h DE_48h-E2F7_MA0758.1 14 bp overlap
Motif DE_60h DE_60h-E2F7_MA0758.1 14 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 366 bp overlap
FIGLA 3 datasets
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FOXA1 3 datasets
ChIP LAPC-4_TFS_p358fs-V5 GSE123618.FOXA1.LAPC-4_TFS_p358fs-V5 190 bp overlap
ChIP LNCaP-abl GSE63034.FOXA1.LNCaP-abl 163 bp overlap
ChIP T-47D_JC4747 GSE126004.FOXA1.T-47D_JC4747 187 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 765 bp overlap
ChIP DE DE-FOXA2-2 783 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 597 bp overlap
ChIP DE DE-GATA4-2 799 bp overlap
ChIP foregut GSE117136.GATA4.foregut 402 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 371 bp overlap
GATA6 15 datasets
ChIP DE DE-GATA6-1 536 bp overlap
ChIP DE DE-GATA6-2 671 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 485 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 802 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 564 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 572 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 754 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 578 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 580 bp overlap
ChIP foregut GSE117136.GATA6.foregut 345 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 493 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 268 bp overlap
GSC 3 datasets
Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
GSC2 3 datasets
Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Gata3 3 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HDAC2 1 dataset
ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 243 bp overlap
Hnf1A 3 datasets
Motif DE_36h DE_36h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap
IRF2 3 datasets
Motif DE_36h DE_36h-IRF2_MA0051.2 16 bp overlap
Motif DE_48h DE_48h-IRF2_MA0051.2 16 bp overlap
Motif DE_60h DE_60h-IRF2_MA0051.2 16 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 317 bp overlap
Lef1 3 datasets
Motif DE_36h DE_36h-Lef1_MA0768.3 8 bp overlap
Motif DE_48h DE_48h-Lef1_MA0768.3 8 bp overlap
Motif DE_60h DE_60h-Lef1_MA0768.3 8 bp overlap
MAFF 3 datasets
Motif DE_36h DE_36h-MAFF_MA0495.4 11 bp overlap
Motif DE_48h DE_48h-MAFF_MA0495.4 11 bp overlap
Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap
MEIS1 3 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MYOD1 3 datasets
Motif DE_36h DE_36h-MYOD1_MA0499.3 9 bp overlap
Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap
Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap
Mecom 3 datasets
Motif DE_36h DE_36h-Mecom_MA0029.2 11 bp overlap
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
NANOG 3 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 240 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 117 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 585 bp overlap
NCOA1 1 dataset
ChIP LS180 GSE39277.NCOA1.LS180 99 bp overlap
NFYB 1 dataset
ChIP WTC11 ENCFF751ZTQ 391 bp overlap
NR6A1 2 datasets
Motif DE_48h DE_48h-NR6A1_MA1541.2 14 bp overlap
Motif DE_60h DE_60h-NR6A1_MA1541.2 14 bp overlap
OTX1 3 datasets
Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
OTX2 3 datasets
Motif DE_36h DE_36h-OTX2_MA0712.3 7 bp overlap
Motif DE_48h DE_48h-OTX2_MA0712.3 7 bp overlap
Motif DE_60h DE_60h-OTX2_MA0712.3 7 bp overlap
PITX1 3 datasets
Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
PITX2 3 datasets
Motif DE_36h DE_36h-PITX2_MA1547.2 8 bp overlap
Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap
Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap
PITX3 3 datasets
Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
PKNOX2 3 datasets
Motif DE_36h DE_36h-PKNOX2_MA0783.1 12 bp overlap
Motif DE_48h DE_48h-PKNOX2_MA0783.1 12 bp overlap
Motif DE_60h DE_60h-PKNOX2_MA0783.1 12 bp overlap
POU2F1 3 datasets
Motif DE_36h DE_36h-POU2F1_MA0785.2 9 bp overlap
Motif DE_48h DE_48h-POU2F1_MA0785.2 9 bp overlap
Motif DE_60h DE_60h-POU2F1_MA0785.2 9 bp overlap
POU2F2 3 datasets
Motif DE_36h DE_36h-POU2F2_MA0507.3 13 bp overlap
Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap
Motif DE_60h DE_60h-POU2F2_MA0507.3 13 bp overlap
POU2F3 3 datasets
Motif DE_36h DE_36h-POU2F3_MA0627.3 9 bp overlap
Motif DE_48h DE_48h-POU2F3_MA0627.3 9 bp overlap
Motif DE_60h DE_60h-POU2F3_MA0627.3 9 bp overlap
POU3F1 3 datasets
Motif DE_36h DE_36h-POU3F1_MA0786.2 10 bp overlap
Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap
Motif DE_60h DE_60h-POU3F1_MA0786.2 10 bp overlap
POU3F2 3 datasets
Motif DE_36h DE_36h-POU3F2_MA0787.1 12 bp overlap
Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap
Motif DE_60h DE_60h-POU3F2_MA0787.1 12 bp overlap
POU3F3 3 datasets
Motif DE_36h DE_36h-POU3F3_MA0788.1 13 bp overlap
Motif DE_48h DE_48h-POU3F3_MA0788.1 13 bp overlap
Motif DE_60h DE_60h-POU3F3_MA0788.1 13 bp overlap
POU3F4 3 datasets
Motif DE_36h DE_36h-POU3F4_MA0789.1 9 bp overlap
Motif DE_48h DE_48h-POU3F4_MA0789.1 9 bp overlap
Motif DE_60h DE_60h-POU3F4_MA0789.1 9 bp overlap
POU5F1B 3 datasets
Motif DE_36h DE_36h-POU5F1B_MA0792.1 9 bp overlap
Motif DE_48h DE_48h-POU5F1B_MA0792.1 9 bp overlap
Motif DE_60h DE_60h-POU5F1B_MA0792.1 9 bp overlap
PPARG 3 datasets
Motif DE_36h DE_36h-PPARG_MA0066.2 19 bp overlap
Motif DE_48h DE_48h-PPARG_MA0066.2 19 bp overlap
Motif DE_60h DE_60h-PPARG_MA0066.2 19 bp overlap
RAD21 1 dataset
ChIP HAP1 GSE126634.RAD21.HAP1 435 bp overlap
RBPJ 3 datasets
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
RHOXF1 3 datasets
Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
RREB1 3 datasets
Motif DE_36h DE_36h-RREB1_MA0073.2 19 bp overlap
Motif DE_48h DE_48h-RREB1_MA0073.2 19 bp overlap
Motif DE_60h DE_60h-RREB1_MA0073.2 19 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 475 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 259 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 256 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 313 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 156 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 243 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 429 bp overlap
SOX13 3 datasets
Motif DE_36h DE_36h-SOX13_MA1120.2 7 bp overlap
Motif DE_48h DE_48h-SOX13_MA1120.2 7 bp overlap
Motif DE_60h DE_60h-SOX13_MA1120.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 478 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 582 bp overlap
SOX2 5 datasets
Motif DE_36h DE_36h-SOX2_MA0143.5 7 bp overlap
Motif DE_48h DE_48h-SOX2_MA0143.5 7 bp overlap
Motif DE_60h DE_60h-SOX2_MA0143.5 7 bp overlap
ChIP HNSC GSE69479.SOX2.HNSC 300 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 269 bp overlap
SPI1 1 dataset
ChIP KG-1 GSE128834.SPI1.KG-1 202 bp overlap
Six3 3 datasets
Motif DE_36h DE_36h-Six3_MA0631.2 11 bp overlap
Motif DE_48h DE_48h-Six3_MA0631.2 11 bp overlap
Motif DE_60h DE_60h-Six3_MA0631.2 11 bp overlap
Sox17 3 datasets
Motif DE_36h DE_36h-Sox17_MA0078.3 10 bp overlap
Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap
Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap
Sox3 3 datasets
Motif DE_36h DE_36h-Sox3_MA0514.3 7 bp overlap
Motif DE_48h DE_48h-Sox3_MA0514.3 7 bp overlap
Motif DE_60h DE_60h-Sox3_MA0514.3 7 bp overlap
Sox5 3 datasets
Motif DE_36h DE_36h-Sox5_MA0087.3 8 bp overlap
Motif DE_48h DE_48h-Sox5_MA0087.3 8 bp overlap
Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap
Sox6 3 datasets
Motif DE_36h DE_36h-Sox6_MA0515.1 10 bp overlap
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap
Sox7 3 datasets
Motif DE_36h DE_36h-Sox7_MA2095.1 10 bp overlap
Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap
Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 271 bp overlap
TCF4 3 datasets
Motif DE_36h DE_36h-TCF4_MA0830.3 8 bp overlap
Motif DE_48h DE_48h-TCF4_MA0830.3 8 bp overlap
Motif DE_60h DE_60h-TCF4_MA0830.3 8 bp overlap
TCF7 3 datasets
Motif DE_36h DE_36h-TCF7_MA0769.3 7 bp overlap
Motif DE_48h DE_48h-TCF7_MA0769.3 7 bp overlap
Motif DE_60h DE_60h-TCF7_MA0769.3 7 bp overlap
TRPS1 3 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
VEZF1 3 datasets
Motif DE_36h DE_36h-VEZF1_MA1578.2 6 bp overlap
Motif DE_48h DE_48h-VEZF1_MA1578.2 6 bp overlap
Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap
ZEB1 3 datasets
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZNF281 3 datasets
Motif DE_36h DE_36h-ZNF281_MA1630.3 10 bp overlap
Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap
Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap
ZNF384 3 datasets
Motif DE_36h DE_36h-ZNF384_MA1125.2 8 bp overlap
Motif DE_48h DE_48h-ZNF384_MA1125.2 8 bp overlap
Motif DE_60h DE_60h-ZNF384_MA1125.2 8 bp overlap
ZNF460 3 datasets
Motif DE_36h DE_36h-ZNF460_MA1596.1 16 bp overlap
Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap
Motif DE_60h DE_60h-ZNF460_MA1596.1 16 bp overlap
ZNF770 3 datasets
Motif DE_36h DE_36h-ZNF770_MA2099.1 8 bp overlap
Motif DE_48h DE_48h-ZNF770_MA2099.1 8 bp overlap
Motif DE_60h DE_60h-ZNF770_MA2099.1 8 bp overlap
Zfp335 3 datasets
Motif DE_36h DE_36h-Zfp335_MA2002.2 7 bp overlap
Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap
Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap
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