chr8 : 16,504,544 – 16,505,525
981 bp 86 TFs 1 linked gene
This 981 bp open chromatin element is linked to ENSG00000253496 and is bound by 86 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000253496 188.2 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:16,499,544 – 16,510,525
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
86 transcription factors
Source
Cell type
ATF4 2 datasets
Motif DE_36h DE_36h-ATF4_MA0833.3 10 bp overlap
Motif DE_60h DE_60h-ATF4_MA0833.3 10 bp overlap
BARX2 3 datasets
Motif DE_36h DE_36h-BARX2_MA1471.2 9 bp overlap
Motif DE_48h DE_48h-BARX2_MA1471.2 9 bp overlap
Motif DE_60h DE_60h-BARX2_MA1471.2 9 bp overlap
BCL6B 2 datasets
Motif DE_48h DE_48h-BCL6B_MA0731.1 17 bp overlap
Motif DE_60h DE_60h-BCL6B_MA0731.1 17 bp overlap
BHLHE22 2 datasets
Motif DE_36h DE_36h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap
Bach1::Mafk 2 datasets
Motif DE_36h DE_36h-Bach1Mafk_MA0591.2 12 bp overlap
Motif DE_60h DE_60h-Bach1Mafk_MA0591.2 12 bp overlap
Bhlha15 2 datasets
Motif DE_36h DE_36h-Bhlha15_MA1472.3 8 bp overlap
Motif DE_60h DE_60h-Bhlha15_MA1472.3 8 bp overlap
CDK6 1 dataset
ChIP KB_IL GSE52469.CDK6.KB_IL 100 bp overlap
CEBPG 2 datasets
Motif DE_36h DE_36h-CEBPG_MA1636.2 10 bp overlap
Motif DE_60h DE_60h-CEBPG_MA1636.2 10 bp overlap
CTCF 1 dataset
ChIP U-937 ERP008568.CTCF.U-937 212 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 194 bp overlap
EZH2 1 dataset
ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 216 bp overlap
FOXA2 3 datasets
ChIP DE DE-FOXA2-1 548 bp overlap
ChIP DE DE-FOXA2-2 165 bp overlap
ChIP DE DE-FOXA2-2 463 bp overlap
GATA2 3 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 849 bp overlap
ChIP DE DE-GATA4-2 937 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
GATA5 2 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 857 bp overlap
ChIP DE DE-GATA6-2 923 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 772 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 781 bp overlap
GTF2B 1 dataset
ChIP IMR-90_TERT GSE38303.GTF2B.IMR-90_TERT 168 bp overlap
Gata3 5 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HDAC2 1 dataset
ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 204 bp overlap
MAF::NFE2 2 datasets
Motif DE_36h DE_36h-MAFNFE2_MA0501.2 11 bp overlap
Motif DE_60h DE_60h-MAFNFE2_MA0501.2 11 bp overlap
MAFF 1 dataset
Motif DE_48h DE_48h-MAFF_MA0495.4 11 bp overlap
MAFG::NFE2L1 2 datasets
Motif DE_36h DE_36h-MAFGNFE2L1_MA0089.3 11 bp overlap
Motif DE_60h DE_60h-MAFGNFE2L1_MA0089.3 11 bp overlap
MEIS2 1 dataset
Motif DE_48h DE_48h-MEIS2_MA1640.2 9 bp overlap
MGA 3 datasets
Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap
MSC 2 datasets
Motif DE_36h DE_36h-MSC_MA0665.1 10 bp overlap
Motif DE_60h DE_60h-MSC_MA0665.1 10 bp overlap
MTA2 1 dataset
ChIP RH4 GSE155861.MTA2.RH4 279 bp overlap
MYB 1 dataset
ChIP Loucy GSE94000.MYB.Loucy 176 bp overlap
MYF5 2 datasets
Motif DE_36h DE_36h-MYF5_MA1641.2 8 bp overlap
Motif DE_60h DE_60h-MYF5_MA1641.2 8 bp overlap
MYOD1 6 datasets
ChIP RD GSE137168.MYOD1.RD 245 bp overlap
ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 201 bp overlap
ChIP RH30_DMSO GSE85169.MYOD1.RH30_DMSO 470 bp overlap
ChIP RH4 GSE83726.MYOD1.RH4 299 bp overlap
ChIP SMS-CTR GSE137168.MYOD1.SMS-CTR 246 bp overlap
ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 266 bp overlap
Mafb 1 dataset
Motif DE_48h DE_48h-Mafb_MA0117.3 11 bp overlap
NEUROD1 2 datasets
Motif DE_36h DE_36h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap
NFATC3 2 datasets
Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap
Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap
NFIA 3 datasets
Motif DE_36h DE_36h-NFIA_MA0670.2 6 bp overlap
Motif DE_48h DE_48h-NFIA_MA0670.2 6 bp overlap
Motif DE_60h DE_60h-NFIA_MA0670.2 6 bp overlap
NFIC 3 datasets
Motif DE_36h DE_36h-NFIC_MA0161.3 7 bp overlap
Motif DE_48h DE_48h-NFIC_MA0161.3 7 bp overlap
Motif DE_60h DE_60h-NFIC_MA0161.3 7 bp overlap
NFIX 3 datasets
Motif DE_36h DE_36h-NFIX_MA0671.2 6 bp overlap
Motif DE_48h DE_48h-NFIX_MA0671.2 6 bp overlap
Motif DE_60h DE_60h-NFIX_MA0671.2 6 bp overlap
NR2C1 1 dataset
Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap
NR2C2 1 dataset
Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap
NRL 1 dataset
Motif DE_48h DE_48h-NRL_MA0842.3 12 bp overlap
Neurod2 4 datasets
Motif DE_36h DE_36h-Neurod2_MA0668.3 8 bp overlap
Motif DE_36h DE_36h-Neurod2_MA1993.2 6 bp overlap
Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap
Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap
Nfatc1 2 datasets
Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap
Nfe2l2 2 datasets
Motif DE_36h DE_36h-Nfe2l2_MA0150.3 11 bp overlap
Motif DE_60h DE_60h-Nfe2l2_MA0150.3 11 bp overlap
Nr1H2 1 dataset
Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 1 dataset
Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 1 dataset
Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap
ONECUT3 3 datasets
Motif DE_36h DE_36h-ONECUT3_MA0757.2 12 bp overlap
Motif DE_48h DE_48h-ONECUT3_MA0757.2 12 bp overlap
Motif DE_60h DE_60h-ONECUT3_MA0757.2 12 bp overlap
Olig2 2 datasets
Motif DE_36h DE_36h-Olig2_MA1997.2 6 bp overlap
Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap
PAX3 3 datasets
Motif DE_36h DE_36h-PAX3_MA1546.2 14 bp overlap
Motif DE_48h DE_48h-PAX3_MA1546.2 14 bp overlap
Motif DE_60h DE_60h-PAX3_MA1546.2 14 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 292 bp overlap
Pou5f1::Sox2 3 datasets
Motif DE_36h DE_36h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap
Prdm5 2 datasets
Motif DE_36h DE_36h-Prdm5_MA1999.2 11 bp overlap
Motif DE_60h DE_60h-Prdm5_MA1999.2 11 bp overlap
Ptf1A 2 datasets
Motif DE_36h DE_36h-Ptf1A_MA1619.2 8 bp overlap
Motif DE_60h DE_60h-Ptf1A_MA1619.2 8 bp overlap
RARA::RXRA 3 datasets
Motif DE_36h DE_36h-RARARXRA_MA0159.1 17 bp overlap
Motif DE_48h DE_48h-RARARXRA_MA0159.1 17 bp overlap
Motif DE_60h DE_60h-RARARXRA_MA0159.1 17 bp overlap
RBPJ 1 dataset
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
RORA 1 dataset
Motif DE_48h DE_48h-RORA_MA0071.1 10 bp overlap
RORB 1 dataset
Motif DE_48h DE_48h-RORB_MA1150.2 10 bp overlap
RORC 1 dataset
Motif DE_48h DE_48h-RORC_MA1151.2 10 bp overlap
SCRT2 1 dataset
Motif DE_36h DE_36h-SCRT2_MA0744.3 10 bp overlap
SIX2 3 datasets
ChIP HEK GSE73865.SIX2.HEK 318 bp overlap
ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 204 bp overlap
ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 322 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 822 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 778 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 688 bp overlap
SNAI2 5 datasets
ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 165 bp overlap
ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 322 bp overlap
ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 212 bp overlap
ChIP SMS-CTR_shSNAI2 GSE137168.SNAI2.SMS-CTR_shSNAI2 387 bp overlap
ChIP SMS-CTR_shSNAI2 GSE137168.SNAI2.SMS-CTR_shSNAI2 185 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 800 bp overlap
SPI1 1 dataset
ChIP NCI-H929 GSE56857.SPI1.NCI-H929 116 bp overlap
SREBF1 3 datasets
Motif DE_36h DE_36h-SREBF1_MA0595.1 10 bp overlap
Motif DE_48h DE_48h-SREBF1_MA0595.1 10 bp overlap
Motif DE_60h DE_60h-SREBF1_MA0595.1 10 bp overlap
SREBF2 5 datasets
Motif DE_36h DE_36h-SREBF2_MA0596.1 10 bp overlap
Motif DE_48h DE_48h-SREBF2_MA0596.1 10 bp overlap
Motif DE_48h DE_48h-SREBF2_MA0596.1 10 bp overlap
Motif DE_60h DE_60h-SREBF2_MA0596.1 10 bp overlap
Motif DE_60h DE_60h-SREBF2_MA0596.1 10 bp overlap
Stat2 3 datasets
Motif DE_36h DE_36h-Stat2_MA1623.2 10 bp overlap
Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
TAL1 1 dataset
ChIP PRIMA2 GSE33850.TAL1.PRIMA2 200 bp overlap
TAL1::TCF3 2 datasets
Motif DE_36h DE_36h-TAL1TCF3_MA0091.2 10 bp overlap
Motif DE_60h DE_60h-TAL1TCF3_MA0091.2 10 bp overlap
TBX18 3 datasets
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
TFAP2A 2 datasets
Motif DE_36h DE_36h-TFAP2A_MA0003.5 9 bp overlap
Motif DE_60h DE_60h-TFAP2A_MA0003.5 9 bp overlap
TFAP2B 2 datasets
Motif DE_36h DE_36h-TFAP2B_MA0812.2 9 bp overlap
Motif DE_60h DE_60h-TFAP2B_MA0812.2 9 bp overlap
TFAP2C 2 datasets
Motif DE_36h DE_36h-TFAP2C_MA0814.3 9 bp overlap
Motif DE_60h DE_60h-TFAP2C_MA0814.3 9 bp overlap
TFAP2E 2 datasets
Motif DE_36h DE_36h-TFAP2E_MA1569.2 9 bp overlap
Motif DE_60h DE_60h-TFAP2E_MA1569.2 9 bp overlap
TFAP4 2 datasets
Motif DE_36h DE_36h-TFAP4_MA0691.1 10 bp overlap
Motif DE_60h DE_60h-TFAP4_MA0691.1 10 bp overlap
TRPS1 5 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Tcf12 2 datasets
Motif DE_36h DE_36h-Tcf12_MA0521.3 6 bp overlap
Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap
Tcf21 2 datasets
Motif DE_36h DE_36h-Tcf21_MA0832.2 10 bp overlap
Motif DE_60h DE_60h-Tcf21_MA0832.2 10 bp overlap
Twist2 2 datasets
Motif DE_36h DE_36h-Twist2_MA0633.3 6 bp overlap
Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap
Yy1 6 datasets
Motif DE_36h DE_36h-Yy1_MA0095.4 8 bp overlap
Motif DE_36h DE_36h-Yy1_MA0095.4 8 bp overlap
Motif DE_48h DE_48h-Yy1_MA0095.4 8 bp overlap
Motif DE_48h DE_48h-Yy1_MA0095.4 8 bp overlap
Motif DE_60h DE_60h-Yy1_MA0095.4 8 bp overlap
Motif DE_60h DE_60h-Yy1_MA0095.4 8 bp overlap
ZNF317 3 datasets
Motif DE_36h DE_36h-ZNF317_MA1593.2 8 bp overlap
Motif DE_48h DE_48h-ZNF317_MA1593.2 8 bp overlap
Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap
ZNF41 1 dataset
ChIP HEK293 GSE76494.ZNF41.HEK293 208 bp overlap
ZNF547 1 dataset
Motif DE_36h DE_36h-ZNF547_MA2334.1 13 bp overlap
ZNF701 3 datasets
Motif DE_36h DE_36h-ZNF701_MA1987.2 17 bp overlap
Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap
Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap
ZNF708 1 dataset
Motif DE_36h DE_36h-ZNF708_MA1730.2 9 bp overlap
ZNF816 1 dataset
Motif DE_36h DE_36h-ZNF816_MA1719.2 15 bp overlap
Zic2 2 datasets
Motif DE_36h DE_36h-Zic2_MA1629.2 9 bp overlap
Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap
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