chr8 : 13,127,586 – 13,127,955
369 bp 65 TFs 1 linked gene
This 369 bp open chromatin element is linked to DLC1 and is bound by 65 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
DLC1 5.5 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:13,122,586 – 13,132,955
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
65 transcription factors
Source
Cell type
ARID2 2 datasets
ChIP Aska-SS GSE108025.ARID2.Aska-SS 280 bp overlap
ChIP Aska-SS_shSSX GSE108025.ARID2.Aska-SS_shSSX 234 bp overlap
BRD4 5 datasets
ChIP MDA-MB-231_DMSO GSE116879.BRD4.MDA-MB-231_DMSO 369 bp overlap
ChIP MDA-MB-231_DMSO_rDNA GSE116879.BRD4.MDA-MB-231_DMSO_rDNA 369 bp overlap
ChIP MDA-MB-231_JQ1-pos_L GSE136151.BRD4.MDA-MB-231_JQ1-pos_L 152 bp overlap
ChIP MDA-MB-231_JQ1_MGSK2801 GSE116879.BRD4.MDA-MB-231_JQ1_MGSK2801 264 bp overlap
ChIP MDA-MB-231_JQ1_MGSK2801_rDNA GSE116879.BRD4.MDA-MB-231_JQ1_MGSK2801_rDNA 264 bp overlap
BRD9 1 dataset
ChIP MDA-MB-231_DMSO GSE116879.BRD9.MDA-MB-231_DMSO 169 bp overlap
CDK8 1 dataset
ChIP myometrium_PT916 GSE128230.CDK8.myometrium_PT916 102 bp overlap
CHD7 2 datasets
ChIP hiPSC_AF22_abD3F5 GSE108506.CHD7.hiPSC_AF22_abD3F5 250 bp overlap
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 316 bp overlap
CTCF 2 datasets
ChIP GP5D GSE51234.CTCF.GP5D 80 bp overlap
ChIP heart_left-ventricle ENCSR544APK.CTCF.heart_left-ventricle 224 bp overlap
E2F1 1 dataset
ChIP MDA-MB-231 GSE95303.E2F1.MDA-MB-231 146 bp overlap
ELF1 2 datasets
ChIP K-562 ENCSR000BMD.ELF1.K-562 147 bp overlap
ChIP K562 ENCFF496AKI 273 bp overlap
EP300 3 datasets
ChIP upper lobe of left lung ENCFF024QBJ 118 bp overlap
ChIP upper lobe of left lung ENCFF306FRW 314 bp overlap
ChIP upper lobe of left lung ENCFF720RAR 241 bp overlap
ERG 1 dataset
ChIP HUVEC-C GSE124891.ERG.HUVEC-C 202 bp overlap
ESR1 1 dataset
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 212 bp overlap
ESR1_pS118 1 dataset
ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 358 bp overlap
ESRRG 1 dataset
ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 172 bp overlap
ETS1 2 datasets
ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 332 bp overlap
ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 205 bp overlap
EZH2 1 dataset
ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 241 bp overlap
FLI1 3 datasets
ChIP A-673_D11 GSE129155.FLI1.A-673_D11 280 bp overlap
ChIP A-673_D14 GSE129155.FLI1.A-673_D14 224 bp overlap
ChIP A-673_D17 GSE129155.FLI1.A-673_D17 231 bp overlap
GATA6 2 datasets
ChIP DE_D1 S41-DE-d1-GATA6-exp2 363 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 363 bp overlap
HAND2 1 dataset
Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap
HMGB2 1 dataset
ChIP HUVEC-C GSE98245.HMGB2.HUVEC-C 315 bp overlap
HNF4A 1 dataset
ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 104 bp overlap
HNRNPH1 2 datasets
ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 238 bp overlap
ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 230 bp overlap
IKZF1 1 dataset
ChIP K-562 ENCSR395HWC.IKZF1.K-562 149 bp overlap
IKZF3 1 dataset
ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 155 bp overlap
JUN 4 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 294 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 369 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 369 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 364 bp overlap
KMT2A 5 datasets
ChIP HEK293T_N-term GSE90762.KMT2A.HEK293T_N-term 341 bp overlap
ChIP HEK293T_N-term_C104 GSE90762.KMT2A.HEK293T_N-term_C104 224 bp overlap
ChIP HEK293T_N-term_C49 GSE90762.KMT2A.HEK293T_N-term_C49 258 bp overlap
ChIP HEK293T_N-term_shCtrl_TASP1-KO GSE90762.KMT2A.HEK293T_N-term_shCtrl_TASP1-KO 224 bp overlap
ChIP Hep-G2 ENCSR692GFR.KMT2A.Hep-G2 123 bp overlap
MAFA 1 dataset
Motif DE_12h DE_12h-MAFA_MA1521.2 13 bp overlap
MED12 2 datasets
ChIP myometrium_PT1063 GSE128230.MED12.myometrium_PT1063 97 bp overlap
ChIP myometrium_PT916 GSE128230.MED12.myometrium_PT916 78 bp overlap
MYBL2 1 dataset
ChIP A-673 GSE119971.MYBL2.A-673 369 bp overlap
NANOG 4 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 312 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 222 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 117 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 189 bp overlap
NFIA 1 dataset
Motif DE_12h DE_12h-NFIA_MA0670.2 6 bp overlap
NFIX 1 dataset
Motif DE_12h DE_12h-NFIX_MA0671.2 6 bp overlap
NKX2-1 1 dataset
ChIP NCI-H3122 GSE39998.NKX2-1.NCI-H3122 229 bp overlap
NR2F2 5 datasets
ChIP K-562 ENCSR000BRS.NR2F2.K-562 162 bp overlap
ChIP liver ENCFF427MRU 338 bp overlap
ChIP liver ENCFF565JGD 244 bp overlap
ChIP liver ENCSR168SMX.NR2F2.liver 369 bp overlap
ChIP liver ENCSR338MMB.NR2F2.liver 245 bp overlap
NR3C1 4 datasets
ChIP A-549 ENCSR000BHF.NR3C1.A-549 167 bp overlap
ChIP A-549 ENCSR000BJR.NR3C1.A-549 104 bp overlap
ChIP BEAS-2B_DEX GSE125623.NR3C1.BEAS-2B_DEX 192 bp overlap
ChIP MDA-MB-231 GSE152203.NR3C1.MDA-MB-231 212 bp overlap
PGR 1 dataset
Motif DE_12h DE_12h-PGR_MA2327.1 9 bp overlap
PHIP 1 dataset
ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 369 bp overlap
POLR2A 17 datasets
ChIP adrenal gland ENCFF843OBJ 339 bp overlap
ChIP endothelial cell of umbilical vein ENCFF091YHT 363 bp overlap
ChIP endothelial cell of umbilical vein ENCFF303XUJ 369 bp overlap
ChIP esophagus muscularis mucosa ENCFF759BBR 354 bp overlap
ChIP esophagus muscularis mucosa ENCFF791ZXN 269 bp overlap
ChIP gastrocnemius medialis ENCFF145VIB 369 bp overlap
ChIP gastroesophageal sphincter ENCFF238INU 369 bp overlap
ChIP sigmoid colon ENCFF754JQR 350 bp overlap
ChIP spleen ENCFF044PYR 144 bp overlap
ChIP spleen ENCFF446ZGT 204 bp overlap
ChIP stomach ENCFF607ZPU 325 bp overlap
ChIP stomach ENCFF820WZN 345 bp overlap
ChIP upper lobe of left lung ENCFF095BJW 339 bp overlap
ChIP upper lobe of left lung ENCFF199JUI 357 bp overlap
ChIP upper lobe of left lung ENCFF504HCM 315 bp overlap
ChIP upper lobe of left lung ENCFF603FIH 257 bp overlap
ChIP upper lobe of left lung ENCFF640VPA 346 bp overlap
PRDM15 1 dataset
ChIP WTC11 ENCFF108TMF 319 bp overlap
Pgr 1 dataset
Motif DE_12h DE_12h-Pgr_MA2323.1 17 bp overlap
RELA 3 datasets
ChIP aortic-endothelial-cell_IL1B_D10 GSE139377.RELA.aortic-endothelial-cell_IL1B_D10 198 bp overlap
ChIP aortic-endothelial-cell_IL1B_D13 GSE139377.RELA.aortic-endothelial-cell_IL1B_D13 185 bp overlap
ChIP aortic-endothelial-cell_IL1B_D33 GSE139377.RELA.aortic-endothelial-cell_IL1B_D33 154 bp overlap
RXRA 1 dataset
ChIP liver ENCFF077DAP 341 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 234 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 336 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 369 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 256 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 369 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 227 bp overlap
SMARCA4 2 datasets
ChIP NPC_K755R-siCT GSE122631.SMARCA4.NPC_K755R-siCT 131 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 348 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 288 bp overlap
SMARCC1 1 dataset
ChIP hiPSC GSE124903.SMARCC1.hiPSC 342 bp overlap
SMC1 1 dataset
ChIP HCAEC GSE101921.SMC1.HCAEC 369 bp overlap
SP1 1 dataset
ChIP liver ENCFF769YSM 369 bp overlap
SP5 1 dataset
Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap
SS18 1 dataset
ChIP Aska-SS_BAF47KO1 GSE108025.SS18.Aska-SS_BAF47KO1 369 bp overlap
Sox11 1 dataset
Motif DE_12h DE_12h-Sox11_MA0869.3 8 bp overlap
T 1 dataset
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 284 bp overlap
TBX3 1 dataset
Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap
TERF2 1 dataset
ChIP LCL GSE55053.TERF2.LCL 122 bp overlap
THAP1 1 dataset
Motif DE_12h DE_12h-THAP1_MA0597.3 8 bp overlap
THRA 1 dataset
Motif DE_12h DE_12h-THRA_MA1969.2 18 bp overlap
ZNF182 1 dataset
ChIP HEK293T GSE78099.ZNF182.HEK293T 115 bp overlap
ZNF274 1 dataset
ChIP Hep-G2 ENCSR871VNN.ZNF274.Hep-G2 309 bp overlap
ZNF320 1 dataset
Motif DE_12h DE_12h-ZNF320_MA1976.2 20 bp overlap
ZNF354C 1 dataset
Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap
ZNF501 1 dataset
ChIP Hep-G2 ENCSR227PHM.ZNF501.Hep-G2 204 bp overlap
ZNF598 1 dataset
ChIP Hep-G2 ENCSR173NAL.ZNF598.Hep-G2 203 bp overlap
ZNF675 1 dataset
Motif DE_12h DE_12h-ZNF675_MA1714.2 19 bp overlap
ZNF83 1 dataset
ChIP K-562 ENCSR257XVY.ZNF83.K-562 239 bp overlap
ZNF90 1 dataset
ChIP HEK293T GSE78099.ZNF90.HEK293T 66 bp overlap
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