chr8 : 1,765,557 – 1,766,098
541 bp 71 TFs 3 linked genes
This 541 bp open chromatin element is linked to KBTBD11-OT1, CLN8, and CLN8-AS1 and is bound by 71 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
KBTBD11-OT1 1.7 kb Proximal Proximity
CLN8 1.7 kb Proximal Proximity
CLN8-AS1 2.2 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:1,760,557 – 1,771,098
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
71 transcription factors
Source
Cell type
ARID1A 3 datasets
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 311 bp overlap
ChIP endometrial-epithelial-cells GSE106660.ARID1A.endometrial-epithelial-cells 377 bp overlap
ChIP endometrial-epithelial-cells_KO GSE106660.ARID1A.endometrial-epithelial-cells_KO 319 bp overlap
ARNT 1 dataset
ChIP SK-MEL-28 GSE85352.ARNT.SK-MEL-28 427 bp overlap
BRD4 3 datasets
ChIP CHL-1 GSE95585.BRD4.CHL-1 482 bp overlap
ChIP CHL-1_OTX015 GSE95585.BRD4.CHL-1_OTX015 88 bp overlap
ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 185 bp overlap
CDX2 1 dataset
ChIP intestinal-cell GSE115314.CDX2.intestinal-cell 280 bp overlap
ERF::FOXI1 2 datasets
Motif DE_60h DE_60h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_72h DE_72h-ERFFOXI1_MA1935.2 10 bp overlap
ERG 1 dataset
ChIP aortic-endothelial-cell_D16 GSE139377.ERG.aortic-endothelial-cell_D16 144 bp overlap
ESR1 5 datasets
ChIP MCF-7_D538G_DMSO GSE148277.ESR1.MCF-7_D538G_DMSO 296 bp overlap
ChIP MCF-7_RUNX2_DOX GSE86538.ESR1.MCF-7_RUNX2_DOX 223 bp overlap
ChIP MCF-7_estrogen GSE133941.ESR1.MCF-7_estrogen 215 bp overlap
ChIP T-47D_flp-ctrl GSE99479.ESR1.T-47D_flp-ctrl 173 bp overlap
ChIP breast_tumor_Male_10 GSE104399.ESR1.breast_tumor_Male_10 532 bp overlap
ETV2 2 datasets
Motif DE_60h DE_60h-ETV2_MA0762.2 9 bp overlap
Motif DE_72h DE_72h-ETV2_MA0762.2 9 bp overlap
ETV2::FOXI1 2 datasets
Motif DE_60h DE_60h-ETV2FOXI1_MA1942.2 11 bp overlap
Motif DE_72h DE_72h-ETV2FOXI1_MA1942.2 11 bp overlap
FLI1 2 datasets
ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 378 bp overlap
ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 240 bp overlap
FLI1::FOXI1 2 datasets
Motif DE_60h DE_60h-FLI1FOXI1_MA1950.2 11 bp overlap
Motif DE_72h DE_72h-FLI1FOXI1_MA1950.2 11 bp overlap
FOS 2 datasets
ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 191 bp overlap
ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 183 bp overlap
FOXA1 5 datasets
ChIP LAPC-4_CST_DHT GSE123618.FOXA1.LAPC-4_CST_DHT 99 bp overlap
ChIP LAPC-4_TFS_p358fs-V5 GSE123618.FOXA1.LAPC-4_TFS_p358fs-V5 95 bp overlap
ChIP LNCaP_TFS GSE123618.FOXA1.LNCaP_TFS 102 bp overlap
ChIP T-47D_8h GSE137579.FOXA1.T-47D_8h 140 bp overlap
ChIP T-47D_shRNF2 GSE137579.FOXA1.T-47D_shRNF2 224 bp overlap
FOXA2 4 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 226 bp overlap
ChIP BJ1-hTERT_MimoRelease GSE92491.FOXA2.BJ1-hTERT_MimoRelease 170 bp overlap
ChIP DE DE-FOXA2-1 448 bp overlap
ChIP DE DE-FOXA2-2 469 bp overlap
FOXF1 1 dataset
ChIP GIST48 GSE106624.FOXF1.GIST48 92 bp overlap
FOXH1 2 datasets
Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap
Motif DE_72h DE_72h-FOXH1_MA0479.2 8 bp overlap
FOXO1::ELF1 2 datasets
Motif DE_60h DE_60h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_72h DE_72h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::FLI1 2 datasets
Motif DE_60h DE_60h-FOXO1FLI1_MA1956.2 13 bp overlap
Motif DE_72h DE_72h-FOXO1FLI1_MA1956.2 13 bp overlap
FOXP2 1 dataset
ChIP PFSK1 ENCSR000BGA.FOXP2.PFSK1 93 bp overlap
GATA1 7 datasets
Motif DE_60h DE_60h-GATA1_MA0035.5 7 bp overlap
Motif DE_72h DE_72h-GATA1_MA0035.5 7 bp overlap
ChIP K-562 GSE107726.GATA1.K-562 298 bp overlap
ChIP K-562_MYO1D-Hub_KO GSE107726.GATA1.K-562_MYO1D-Hub_KO 177 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 191 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 225 bp overlap
ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 291 bp overlap
GATA2 16 datasets
ChIP ESF GSE108408.GATA2.ESF 541 bp overlap
ChIP HUVEC-C GSE109625.GATA2.HUVEC-C 234 bp overlap
ChIP HUVEC-C_VEGF_12h GSE109625.GATA2.HUVEC-C_VEGF_12h 159 bp overlap
ChIP HUVEC-C_VEGF_1h GSE109625.GATA2.HUVEC-C_VEGF_1h 259 bp overlap
ChIP HUVEC-C_VEGF_4h GSE109625.GATA2.HUVEC-C_VEGF_4h 242 bp overlap
ChIP Hep-G2 ENCSR897LDT.GATA2.Hep-G2 202 bp overlap
ChIP HepG2 ENCFF905PYM 305 bp overlap
ChIP VCaP_JQ1 GSE125236.GATA2.VCaP_JQ1 150 bp overlap
ChIP dermal-fibroblast GSE51025.GATA2.dermal-fibroblast 196 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 288 bp overlap
ChIP endothelial cell of umbilical vein ENCFF148NLK 195 bp overlap
ChIP endothelial_umbilical-vein ENCSR000EVW.GATA2.endothelial_umbilical-vein 380 bp overlap
ChIP primary-endometrial-stromal-cell_IVD_P1 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P1 541 bp overlap
ChIP primary-endometrial-stromal-cell_IVD_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P2 396 bp overlap
ChIP primary-endometrial-stromal-cell_Veh_P1 GSE145673.GATA2.primary-endometrial-stromal-cell_Veh_P1 438 bp overlap
ChIP primary-endometrial-stromal-cell_Veh_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_Veh_P2 403 bp overlap
GATA3 7 datasets
ChIP Jurkat GSE120063.GATA3.Jurkat 281 bp overlap
ChIP MCF-7 GSE122847.GATA3.MCF-7 266 bp overlap
ChIP MCF-7 GSE133072.GATA3.MCF-7 263 bp overlap
ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 248 bp overlap
ChIP SK-N-SH ENCFF040SSB 287 bp overlap
ChIP T-47D ENCSR000BMX.GATA3.T-47D 210 bp overlap
ChIP T-47D_sc GSE122847.GATA3.T-47D_sc 199 bp overlap
GATA3_Cter 2 datasets
ChIP T-47D_CR3flp GSE99479.GATA3_Cter.T-47D_CR3flp 211 bp overlap
ChIP T-47D_flp-ctrl GSE99479.GATA3_Cter.T-47D_flp-ctrl 167 bp overlap
GATA3_Nter 2 datasets
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 265 bp overlap
ChIP T-47D_flp-ctrl GSE99479.GATA3_Nter.T-47D_flp-ctrl 274 bp overlap
GATA4 8 datasets
ChIP BJ1-hTERT GSE92491.GATA4.BJ1-hTERT 365 bp overlap
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 304 bp overlap
ChIP DE DE-GATA4-1 464 bp overlap
ChIP DE DE-GATA4-2 541 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 186 bp overlap
ChIP foregut GSE117136.GATA4.foregut 498 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 463 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 321 bp overlap
GATA6 15 datasets
ChIP DE DE-GATA6-1 461 bp overlap
ChIP DE DE-GATA6-2 532 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 521 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 541 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 541 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 541 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 541 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 541 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 444 bp overlap
ChIP foregut GSE117136.GATA6.foregut 415 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 310 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 428 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 288 bp overlap
Gata3 2 datasets
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
Hand1::Tcf3 2 datasets
Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_72h DE_72h-Hand1Tcf3_MA0092.2 9 bp overlap
IKZF1 3 datasets
Motif DE_60h DE_60h-IKZF1_MA1508.2 8 bp overlap
Motif DE_72h DE_72h-IKZF1_MA1508.2 8 bp overlap
ChIP K-562 ENCSR395HWC.IKZF1.K-562 225 bp overlap
JUN 6 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 393 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 371 bp overlap
ChIP HAEC_IL1b_4h GSE89970.JUN.HAEC_IL1b_4h 205 bp overlap
ChIP HAEC_TNFa_4h GSE89970.JUN.HAEC_TNFa_4h 168 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 464 bp overlap
ChIP endothelial_umbilical-vein ENCSR000EFA.JUN.endothelial_umbilical-vein 143 bp overlap
JUNB 1 dataset
ChIP HAEC GSE89970.JUNB.HAEC 157 bp overlap
JUND 1 dataset
ChIP SK-N-SH ENCSR000BSK.JUND.SK-N-SH 175 bp overlap
KMT2A 1 dataset
ChIP MV4-11 GSE79899.KMT2A.MV4-11 212 bp overlap
MEIS1 2 datasets
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MEN1 1 dataset
ChIP MCF-7 GSE85317.MEN1.MCF-7 127 bp overlap
MSANTD3 2 datasets
Motif DE_60h DE_60h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_72h DE_72h-MSANTD3_MA1523.2 7 bp overlap
MYCN 1 dataset
ChIP LNCaP_DHT GSE117304.MYCN.LNCaP_DHT 149 bp overlap
Mecom 2 datasets
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
NFIC 2 datasets
ChIP SK-N-SH ENCFF965AKM 150 bp overlap
ChIP SK-N-SH ENCSR000BSV.NFIC.SK-N-SH 245 bp overlap
NKX2-2 2 datasets
Motif DE_60h DE_60h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_72h DE_72h-NKX2-2_MA1645.2 8 bp overlap
PBX3 1 dataset
ChIP SK-N-SH ENCFF876BMC 263 bp overlap
PHOX2B 2 datasets
Motif DE_60h DE_60h-PHOX2B_MA0681.3 12 bp overlap
Motif DE_72h DE_72h-PHOX2B_MA0681.3 12 bp overlap
POLR2A 2 datasets
ChIP PFSK-1 ENCFF576NIT 415 bp overlap
ChIP PFSK-1 ENCFF576NIT 123 bp overlap
PRDM6 3 datasets
ChIP HEK293 ENCFF283AJL 391 bp overlap
ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 460 bp overlap
ChIP HEK293 GSE76494.PRDM6.HEK293 409 bp overlap
PROP1 2 datasets
Motif DE_60h DE_60h-PROP1_MA0715.1 11 bp overlap
Motif DE_72h DE_72h-PROP1_MA0715.1 11 bp overlap
Prdm4 1 dataset
Motif DE_72h DE_72h-Prdm4_MA1647.3 11 bp overlap
RAD21 1 dataset
ChIP HAP1 GSE126634.RAD21.HAP1 147 bp overlap
SIN3A 1 dataset
ChIP PFSK1 ENCSR000BOY.SIN3A.PFSK1 121 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 487 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 458 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 492 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 541 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 541 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 541 bp overlap
SMARCA4 2 datasets
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 190 bp overlap
ChIP MCF-7 GSE140185.SMARCA4.MCF-7 303 bp overlap
SMARCC1 3 datasets
ChIP DE_D1 S10-DE-d1-BAF155-exp1 541 bp overlap
ChIP DE_D1 S15-DE-d1-BAF155-exp1 541 bp overlap
ChIP SYO-1_shCt GSE139053.SMARCC1.SYO-1_shCt 282 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 313 bp overlap
SREBP2 1 dataset
ChIP monocyte_TNF GSE129202.SREBP2.monocyte_TNF 498 bp overlap
SS18 2 datasets
ChIP SYO-1 GSE108025.SS18.SYO-1 325 bp overlap
ChIP SYO-1_shCt GSE139053.SS18.SYO-1_shCt 386 bp overlap
SUPT5H 1 dataset
ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 359 bp overlap
Sox1 2 datasets
Motif DE_60h DE_60h-Sox1_MA0870.1 15 bp overlap
Motif DE_72h DE_72h-Sox1_MA0870.1 15 bp overlap
TCF12 1 dataset
ChIP SK-N-SH ENCFF147AHB 328 bp overlap
TCF7L2 2 datasets
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap
TEAD1 6 datasets
Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap
Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap
Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap
Motif DE_72h DE_72h-TEAD1_MA0090.4 9 bp overlap
ChIP K-562 ENCSR591ASD.TEAD1.K-562 201 bp overlap
ChIP K562 ENCFF465AQA 297 bp overlap
TEAD2 2 datasets
Motif DE_60h DE_60h-TEAD2_MA1121.2 7 bp overlap
Motif DE_72h DE_72h-TEAD2_MA1121.2 7 bp overlap
TEAD3 4 datasets
Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap
Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap
Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap
Motif DE_72h DE_72h-TEAD3_MA0808.1 8 bp overlap
TEAD4 5 datasets
Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap
Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap
ChIP K562 ENCFF673NIK 303 bp overlap
ChIP SK-N-SH ENCSR000BUQ.TEAD4.SK-N-SH 171 bp overlap
ChIP T-47D_Veh GSE125594.TEAD4.T-47D_Veh 291 bp overlap
TRPS1 3 datasets
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ChIP T-47D GSE107013.TRPS1.T-47D 183 bp overlap
ZEB2 1 dataset
ChIP K-562 ENCSR004GKA.ZEB2.K-562 100 bp overlap
ZIM3 2 datasets
Motif DE_60h DE_60h-ZIM3_MA1709.2 11 bp overlap
Motif DE_72h DE_72h-ZIM3_MA1709.2 11 bp overlap
ZNF136 2 datasets
Motif DE_60h DE_60h-ZNF136_MA1588.1 15 bp overlap
Motif DE_72h DE_72h-ZNF136_MA1588.1 15 bp overlap
ZNF274 2 datasets
Motif DE_60h DE_60h-ZNF274_MA1592.2 12 bp overlap
Motif DE_72h DE_72h-ZNF274_MA1592.2 12 bp overlap
ZNF629 1 dataset
ChIP HEK293 ENCSR351NON.ZNF629.HEK293 451 bp overlap
ZNF660 1 dataset
ChIP HEK293 ENCSR283DOU.ZNF660.HEK293 196 bp overlap
ZSCAN5C 2 datasets
ChIP HEK293 ENCFF343DTU 266 bp overlap
ChIP HEK293 ENCSR731AGO.ZSCAN5C.HEK293 272 bp overlap
Huangfu Lab · Publications · Resources · Contact