chr7 : 10,975,796 – 10,976,412

616 bp 68 TFs 1 linked gene

This 616 bp open chromatin element is linked to PHF14 and is bound by 68 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
PHF14		2.5 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

68 transcription factors

ASH2L 1 dataset

ChIP Hep-G2 ENCSR508LMH.ASH2L.Hep-G2 277 bp overlap

ATF2 2 datasets

Motif DE_36h DE_36h-ATF2_MA1632.2 10 bp overlap

Motif DE_60h DE_60h-ATF2_MA1632.2 10 bp overlap

ATF3 2 datasets

Motif DE_36h DE_36h-ATF3_MA0605.3 10 bp overlap

Motif DE_60h DE_60h-ATF3_MA0605.3 10 bp overlap

ATF7 2 datasets

Motif DE_36h DE_36h-ATF7_MA0834.2 10 bp overlap

Motif DE_60h DE_60h-ATF7_MA0834.2 10 bp overlap

CREB1 3 datasets

Motif DE_36h DE_36h-CREB1_MA0018.5 8 bp overlap

Motif DE_60h DE_60h-CREB1_MA0018.5 8 bp overlap

CREM 2 datasets

Motif DE_36h DE_36h-CREM_MA0609.3 10 bp overlap

Motif DE_60h DE_60h-CREM_MA0609.3 10 bp overlap

CTCF 1 dataset

ChIP HAP1_clone25 GSE152721.CTCF.HAP1_clone25 164 bp overlap

Creb5 2 datasets

Motif DE_36h DE_36h-Creb5_MA0840.2 10 bp overlap

Motif DE_60h DE_60h-Creb5_MA0840.2 10 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 339 bp overlap

ESR2 2 datasets

Motif DE_36h DE_36h-ESR2_MA0258.2 15 bp overlap

Motif DE_60h DE_60h-ESR2_MA0258.2 15 bp overlap

FOS::JUN 2 datasets

Motif DE_36h DE_36h-FOSJUN_MA1126.2 10 bp overlap

Motif DE_60h DE_60h-FOSJUN_MA1126.2 10 bp overlap

FOSB::JUNB 2 datasets

Motif DE_36h DE_36h-FOSBJUNB_MA1136.1 10 bp overlap

Motif DE_60h DE_60h-FOSBJUNB_MA1136.1 10 bp overlap

FOSL1::JUN 2 datasets

Motif DE_36h DE_36h-FOSL1JUN_MA1129.1 10 bp overlap

Motif DE_60h DE_60h-FOSL1JUN_MA1129.1 10 bp overlap

FOSL2::JUN 2 datasets

Motif DE_36h DE_36h-FOSL2JUN_MA1131.2 10 bp overlap

Motif DE_60h DE_60h-FOSL2JUN_MA1131.2 10 bp overlap

FOSL2::JUNB 2 datasets

Motif DE_36h DE_36h-FOSL2JUNB_MA1139.2 10 bp overlap

Motif DE_60h DE_60h-FOSL2JUNB_MA1139.2 10 bp overlap

FOSL2::JUND 2 datasets

Motif DE_36h DE_36h-FOSL2JUND_MA1145.2 10 bp overlap

Motif DE_60h DE_60h-FOSL2JUND_MA1145.2 10 bp overlap

FOXA2 3 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 232 bp overlap

ChIP DE DE-FOXA2-1 571 bp overlap

ChIP DE DE-FOXA2-2 506 bp overlap

FOXF2 1 dataset

Motif DE_36h DE_36h-FOXF2_MA0030.2 9 bp overlap

FOXK1 1 dataset

Motif DE_36h DE_36h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_36h DE_36h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_36h DE_36h-FOXL1_MA0033.2 7 bp overlap

FOXO4 1 dataset

Motif DE_36h DE_36h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_36h DE_36h-FOXO6_MA0849.1 7 bp overlap

FOXP2 1 dataset

Motif DE_36h DE_36h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_36h DE_36h-FOXP3_MA0850.1 7 bp overlap

Foxf1 1 dataset

Motif DE_36h DE_36h-Foxf1_MA1606.2 7 bp overlap

Foxj3 1 dataset

Motif DE_36h DE_36h-Foxj3_MA0851.2 9 bp overlap

Foxo1 1 dataset

Motif DE_36h DE_36h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_36h DE_36h-Foxo3_MA0157.4 7 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 607 bp overlap

ChIP DE DE-GATA4-2 577 bp overlap

Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 576 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 309 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 537 bp overlap

ChIP DE DE-GATA6-2 510 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 616 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 590 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 616 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 616 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 615 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 616 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 435 bp overlap

HEXIM1-CDK9 1 dataset

ChIP A-375 GSE68047.HEXIM1-CDK9.A-375 133 bp overlap

IKZF3 1 dataset

ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 282 bp overlap

JDP2 2 datasets

Motif DE_36h DE_36h-JDP2_MA0656.2 10 bp overlap

Motif DE_60h DE_60h-JDP2_MA0656.2 10 bp overlap

JUN 4 datasets

Motif DE_36h DE_36h-JUN_MA0488.2 10 bp overlap

Motif DE_60h DE_60h-JUN_MA0488.2 10 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 278 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 258 bp overlap

JUNB 2 datasets

Motif DE_36h DE_36h-JUNB_MA1140.3 11 bp overlap

Motif DE_60h DE_60h-JUNB_MA1140.3 11 bp overlap

JUND 2 datasets

Motif DE_36h DE_36h-JUND_MA0492.2 11 bp overlap

Motif DE_60h DE_60h-JUND_MA0492.2 11 bp overlap

KMT2A 1 dataset

ChIP HEK293T_N-term_C104 GSE90762.KMT2A.HEK293T_N-term_C104 407 bp overlap

MEF2B 1 dataset

ChIP DOHH2 GSE69558.MEF2B.DOHH2 209 bp overlap

MEN1 1 dataset

ChIP MCF-7 GSE85317.MEN1.MCF-7 58 bp overlap

MYBL2 1 dataset

Motif DE_36h DE_36h-MYBL2_MA0777.1 15 bp overlap

NFATC3 1 dataset

Motif DE_36h DE_36h-NFATC3_MA0625.3 6 bp overlap

NR2C1 2 datasets

Motif DE_36h DE_36h-NR2C1_MA1535.2 6 bp overlap

Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap

NR2C2 2 datasets

Motif DE_36h DE_36h-NR2C2_MA1536.2 6 bp overlap

Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap

Nfatc1 1 dataset

Motif DE_36h DE_36h-Nfatc1_MA0624.3 6 bp overlap

Nr1H2 2 datasets

Motif DE_36h DE_36h-Nr1H2_MA1996.2 6 bp overlap

Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 2 datasets

Motif DE_36h DE_36h-Nr1H4_MA1110.3 6 bp overlap

Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 2 datasets

Motif DE_36h DE_36h-Nr1h3_MA2337.1 6 bp overlap

Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap

Nr2e1 1 dataset

Motif DE_36h DE_36h-Nr2e1_MA0676.1 9 bp overlap

ONECUT3 3 datasets

Motif DE_36h DE_36h-ONECUT3_MA0757.2 12 bp overlap

Motif DE_48h DE_48h-ONECUT3_MA0757.2 12 bp overlap

Motif DE_60h DE_60h-ONECUT3_MA0757.2 12 bp overlap

OVOL1 1 dataset

Motif DE_36h DE_36h-OVOL1_MA1544.2 10 bp overlap

PHIP 1 dataset

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 264 bp overlap

PHOX2B 1 dataset

ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 199 bp overlap

POU2F3 1 dataset

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 262 bp overlap

PRDM10 4 datasets

ChIP HEK293 ENCFF145WQQ 292 bp overlap

ChIP HEK293 ENCFF145WQQ 426 bp overlap

ChIP K-562 ENCSR120MPG.PRDM10.K-562 285 bp overlap

ChIP K562 ENCFF740YLK 417 bp overlap

REL 1 dataset

Motif DE_36h DE_36h-REL_MA0101.1 10 bp overlap

RXRA::VDR 3 datasets

Motif DE_36h DE_36h-RXRAVDR_MA0074.1 15 bp overlap

Motif DE_48h DE_48h-RXRAVDR_MA0074.1 15 bp overlap

Motif DE_60h DE_60h-RXRAVDR_MA0074.1 15 bp overlap

Rarb 3 datasets

Motif DE_36h DE_36h-Rarb_MA0857.1 16 bp overlap

Motif DE_48h DE_48h-Rarb_MA0857.1 16 bp overlap

Motif DE_60h DE_60h-Rarb_MA0857.1 16 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 287 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 476 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 322 bp overlap

SRF 1 dataset

Motif DE_36h DE_36h-SRF_MA0083.3 16 bp overlap

Stat6 1 dataset

Motif DE_36h DE_36h-Stat6_MA0520.2 10 bp overlap

Yy1 1 dataset

Motif DE_36h DE_36h-Yy1_MA0095.4 8 bp overlap

ZBTB17 1 dataset

Motif DE_36h DE_36h-ZBTB17_MA2102.1 8 bp overlap

ZNF8 1 dataset

Motif DE_36h DE_36h-ZNF8_MA1718.1 20 bp overlap

ZSCAN5C 1 dataset

ChIP HEK293 ENCSR731AGO.ZSCAN5C.HEK293 199 bp overlap

Zfp335 1 dataset

Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap