chr5 : 57,019,246 – 57,020,109
863 bp 80 TFs 4 linked genes
This 863 bp open chromatin element is linked to 4 target genes and is bound by 80 transcription factors.
Linked Genes
4 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MIER3 67.6 kb Distal Multiome
SETD9 110.1 kb Distal Multiome
GPBP1 154.3 kb Distal Multiome
MAP3K1 204.2 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:57,014,246 – 57,025,109
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
80 transcription factors
Source
Cell type
Ahr::Arnt 3 datasets
Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_60h DE_60h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap
Arid3a 3 datasets
Motif DE_48h DE_48h-Arid3a_MA0151.1 6 bp overlap
Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap
Motif DE_72h DE_72h-Arid3a_MA0151.1 6 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF364PUR 57 bp overlap
Crx 6 datasets
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
DMRTA2 3 datasets
Motif DE_48h DE_48h-DMRTA2_MA1478.2 6 bp overlap
Motif DE_60h DE_60h-DMRTA2_MA1478.2 6 bp overlap
Motif DE_72h DE_72h-DMRTA2_MA1478.2 6 bp overlap
DUX4 4 datasets
Motif DE_48h DE_48h-DUX4_MA0468.1 11 bp overlap
Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap
Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap
ChIP WA01 GSE94322.DUX4.WA01 197 bp overlap
Dmbx1 3 datasets
Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_72h DE_72h-Dmbx1_MA0883.2 10 bp overlap
ETV2::FIGLA 3 datasets
Motif DE_48h DE_48h-ETV2FIGLA_MA1941.2 13 bp overlap
Motif DE_60h DE_60h-ETV2FIGLA_MA1941.2 13 bp overlap
Motif DE_72h DE_72h-ETV2FIGLA_MA1941.2 13 bp overlap
EWSR1-FLI1 2 datasets
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
Elf5 2 datasets
Motif DE_60h DE_60h-Elf5_MA0136.4 8 bp overlap
Motif DE_72h DE_72h-Elf5_MA0136.4 8 bp overlap
FIGLA 3 datasets
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 692 bp overlap
ChIP DE DE-FOXA2-2 552 bp overlap
FOXH1 3 datasets
Motif DE_48h DE_48h-FOXH1_MA0479.2 8 bp overlap
Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap
Motif DE_72h DE_72h-FOXH1_MA0479.2 8 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 744 bp overlap
ChIP DE DE-GATA4-2 863 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 272 bp overlap
GATA5 3 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 12 datasets
ChIP DE DE-GATA6-1 759 bp overlap
ChIP DE DE-GATA6-2 863 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 462 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 599 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 448 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 840 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 319 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 332 bp overlap
ChIP foregut GSE117136.GATA6.foregut 275 bp overlap
GLIS2 3 datasets
Motif DE_48h DE_48h-GLIS2_MA0736.1 14 bp overlap
Motif DE_60h DE_60h-GLIS2_MA0736.1 14 bp overlap
Motif DE_72h DE_72h-GLIS2_MA0736.1 14 bp overlap
GLIS3 3 datasets
Motif DE_48h DE_48h-GLIS3_MA0737.1 14 bp overlap
Motif DE_60h DE_60h-GLIS3_MA0737.1 14 bp overlap
Motif DE_72h DE_72h-GLIS3_MA0737.1 14 bp overlap
GRHL2 6 datasets
Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap
Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap
Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap
Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap
Motif DE_72h DE_72h-GRHL2_MA1105.3 8 bp overlap
Motif DE_72h DE_72h-GRHL2_MA1105.3 8 bp overlap
GSC 6 datasets
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 6 datasets
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Gata3 3 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HLF 1 dataset
ChIP HepG2 ENCFF854JLR 203 bp overlap
Hnf1A 4 datasets
Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap
IKZF2 2 datasets
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap
IRF9 3 datasets
Motif DE_48h DE_48h-IRF9_MA0653.1 15 bp overlap
Motif DE_60h DE_60h-IRF9_MA0653.1 15 bp overlap
Motif DE_72h DE_72h-IRF9_MA0653.1 15 bp overlap
MSANTD3 3 datasets
Motif DE_48h DE_48h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_60h DE_60h-MSANTD3_MA1523.2 7 bp overlap
Motif DE_72h DE_72h-MSANTD3_MA1523.2 7 bp overlap
MYOD1 3 datasets
Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap
Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap
Motif DE_72h DE_72h-MYOD1_MA0499.3 9 bp overlap
NFKB1 3 datasets
Motif DE_48h DE_48h-NFKB1_MA0105.4 13 bp overlap
Motif DE_60h DE_60h-NFKB1_MA0105.4 13 bp overlap
Motif DE_72h DE_72h-NFKB1_MA0105.4 13 bp overlap
NFYA 3 datasets
Motif DE_48h DE_48h-NFYA_MA0060.4 8 bp overlap
Motif DE_60h DE_60h-NFYA_MA0060.4 8 bp overlap
Motif DE_72h DE_72h-NFYA_MA0060.4 8 bp overlap
NFYB 3 datasets
Motif DE_48h DE_48h-NFYB_MA0502.3 9 bp overlap
Motif DE_60h DE_60h-NFYB_MA0502.3 9 bp overlap
Motif DE_72h DE_72h-NFYB_MA0502.3 9 bp overlap
NFYC 3 datasets
Motif DE_48h DE_48h-NFYC_MA1644.2 7 bp overlap
Motif DE_60h DE_60h-NFYC_MA1644.2 7 bp overlap
Motif DE_72h DE_72h-NFYC_MA1644.2 7 bp overlap
NR2C2 1 dataset
Motif DE_60h DE_60h-NR2C2_MA0504.2 14 bp overlap
NR2F1 3 datasets
Motif DE_48h DE_48h-NR2F1_MA1537.2 13 bp overlap
Motif DE_60h DE_60h-NR2F1_MA1537.2 13 bp overlap
Motif DE_72h DE_72h-NR2F1_MA1537.2 13 bp overlap
NR4A1 1 dataset
Motif DE_60h DE_60h-NR4A1_MA1112.3 8 bp overlap
NR4A2 1 dataset
Motif DE_60h DE_60h-NR4A2_MA0160.3 8 bp overlap
Nr2f6 1 dataset
Motif DE_60h DE_60h-Nr2f6_MA0677.2 13 bp overlap
OTX1 6 datasets
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
PBX1 3 datasets
Motif DE_48h DE_48h-PBX1_MA0070.2 9 bp overlap
Motif DE_60h DE_60h-PBX1_MA0070.2 9 bp overlap
Motif DE_72h DE_72h-PBX1_MA0070.2 9 bp overlap
PITX1 6 datasets
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX2 6 datasets
Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap
Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap
Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap
Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap
Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap
Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap
PITX3 6 datasets
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
PLAG1 3 datasets
Motif DE_48h DE_48h-PLAG1_MA0163.1 14 bp overlap
Motif DE_60h DE_60h-PLAG1_MA0163.1 14 bp overlap
Motif DE_72h DE_72h-PLAG1_MA0163.1 14 bp overlap
PPARA::RXRA 4 datasets
Motif DE_48h DE_48h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_60h DE_60h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_60h DE_60h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_72h DE_72h-PPARARXRA_MA1148.2 17 bp overlap
Pparg::Rxra 4 datasets
Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_60h DE_60h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_60h DE_60h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap
Prdm4 3 datasets
Motif DE_48h DE_48h-Prdm4_MA1647.3 11 bp overlap
Motif DE_60h DE_60h-Prdm4_MA1647.3 11 bp overlap
Motif DE_72h DE_72h-Prdm4_MA1647.3 11 bp overlap
RARA::RXRA 3 datasets
Motif DE_48h DE_48h-RARARXRA_MA0159.1 17 bp overlap
Motif DE_60h DE_60h-RARARXRA_MA0159.1 17 bp overlap
Motif DE_72h DE_72h-RARARXRA_MA0159.1 17 bp overlap
RHOXF1 6 datasets
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
RXRA::VDR 3 datasets
Motif DE_48h DE_48h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_60h DE_60h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_72h DE_72h-RXRAVDR_MA0074.1 15 bp overlap
Rhox11 3 datasets
Motif DE_48h DE_48h-Rhox11_MA0629.2 9 bp overlap
Motif DE_60h DE_60h-Rhox11_MA0629.2 9 bp overlap
Motif DE_72h DE_72h-Rhox11_MA0629.2 9 bp overlap
SCRT1 3 datasets
Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap
Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap
Motif DE_72h DE_72h-SCRT1_MA0743.3 10 bp overlap
SCRT2 3 datasets
Motif DE_48h DE_48h-SCRT2_MA0744.3 10 bp overlap
Motif DE_60h DE_60h-SCRT2_MA0744.3 10 bp overlap
Motif DE_72h DE_72h-SCRT2_MA0744.3 10 bp overlap
SIX1 3 datasets
Motif DE_48h DE_48h-SIX1_MA1118.2 9 bp overlap
Motif DE_60h DE_60h-SIX1_MA1118.2 9 bp overlap
Motif DE_72h DE_72h-SIX1_MA1118.2 9 bp overlap
SIX2 3 datasets
Motif DE_48h DE_48h-SIX2_MA1119.2 11 bp overlap
Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap
Motif DE_72h DE_72h-SIX2_MA1119.2 11 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 333 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 470 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 467 bp overlap
SNAI2 3 datasets
Motif DE_48h DE_48h-SNAI2_MA0745.3 8 bp overlap
Motif DE_60h DE_60h-SNAI2_MA0745.3 8 bp overlap
Motif DE_72h DE_72h-SNAI2_MA0745.3 8 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 309 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 505 bp overlap
SPIC 3 datasets
Motif DE_48h DE_48h-SPIC_MA0687.2 13 bp overlap
Motif DE_60h DE_60h-SPIC_MA0687.2 13 bp overlap
Motif DE_72h DE_72h-SPIC_MA0687.2 13 bp overlap
SREBF2 3 datasets
Motif DE_48h DE_48h-SREBF2_MA0596.1 10 bp overlap
Motif DE_60h DE_60h-SREBF2_MA0596.1 10 bp overlap
Motif DE_72h DE_72h-SREBF2_MA0596.1 10 bp overlap
TBX19 3 datasets
Motif DE_48h DE_48h-TBX19_MA0804.2 17 bp overlap
Motif DE_60h DE_60h-TBX19_MA0804.2 17 bp overlap
Motif DE_72h DE_72h-TBX19_MA0804.2 17 bp overlap
TBX5 1 dataset
Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap
TBXT 3 datasets
Motif DE_48h DE_48h-TBXT_MA0009.2 16 bp overlap
Motif DE_60h DE_60h-TBXT_MA0009.2 16 bp overlap
Motif DE_72h DE_72h-TBXT_MA0009.2 16 bp overlap
TCF7L2 4 datasets
Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap
THRB 3 datasets
Motif DE_48h DE_48h-THRB_MA1574.2 13 bp overlap
Motif DE_60h DE_60h-THRB_MA1574.2 13 bp overlap
Motif DE_72h DE_72h-THRB_MA1574.2 13 bp overlap
TRPS1 3 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ZEB1 3 datasets
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZNF274 3 datasets
Motif DE_48h DE_48h-ZNF274_MA1592.2 12 bp overlap
Motif DE_60h DE_60h-ZNF274_MA1592.2 12 bp overlap
Motif DE_72h DE_72h-ZNF274_MA1592.2 12 bp overlap
ZNF282 3 datasets
Motif DE_48h DE_48h-ZNF282_MA1154.2 15 bp overlap
Motif DE_60h DE_60h-ZNF282_MA1154.2 15 bp overlap
Motif DE_72h DE_72h-ZNF282_MA1154.2 15 bp overlap
ZNF354C 3 datasets
Motif DE_48h DE_48h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_72h DE_72h-ZNF354C_MA0130.1 6 bp overlap
ZNF410 3 datasets
Motif DE_48h DE_48h-ZNF410_MA0752.2 16 bp overlap
Motif DE_60h DE_60h-ZNF410_MA0752.2 16 bp overlap
Motif DE_72h DE_72h-ZNF410_MA0752.2 16 bp overlap
ZNF418 3 datasets
Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap
Motif DE_60h DE_60h-ZNF418_MA1980.1 15 bp overlap
Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap
ZNF549 1 dataset
Motif DE_60h DE_60h-ZNF549_MA1728.2 8 bp overlap
ZNF667 1 dataset
Motif DE_72h DE_72h-ZNF667_MA1984.2 11 bp overlap
ZNF675 3 datasets
Motif DE_48h DE_48h-ZNF675_MA1714.2 19 bp overlap
Motif DE_60h DE_60h-ZNF675_MA1714.2 19 bp overlap
Motif DE_72h DE_72h-ZNF675_MA1714.2 19 bp overlap
ZNF684 3 datasets
Motif DE_48h DE_48h-ZNF684_MA1600.2 14 bp overlap
Motif DE_60h DE_60h-ZNF684_MA1600.2 14 bp overlap
Motif DE_72h DE_72h-ZNF684_MA1600.2 14 bp overlap
ZNF701 2 datasets
Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap
Motif DE_72h DE_72h-ZNF701_MA1987.2 17 bp overlap
ZSCAN4 2 datasets
Motif DE_60h DE_60h-ZSCAN4_MA1155.1 15 bp overlap
Motif DE_72h DE_72h-ZSCAN4_MA1155.1 15 bp overlap
Zfp961 3 datasets
Motif DE_48h DE_48h-Zfp961_MA2126.1 8 bp overlap
Motif DE_60h DE_60h-Zfp961_MA2126.1 8 bp overlap
Motif DE_72h DE_72h-Zfp961_MA2126.1 8 bp overlap
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