chr4 : 175,998,915 – 175,999,255

340 bp 64 TFs 1 linked gene

This 340 bp open chromatin element is linked to GPM6A and is bound by 64 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
GPM6A		3.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

64 transcription factors

BCL11A 1 dataset

ChIP WA01 ENCSR000BMJ.BCL11A.WA01 104 bp overlap

BRD4 1 dataset

ChIP HAP1 GSE108387.BRD4.HAP1 199 bp overlap

CHD2 1 dataset

ChIP H1 ENCFF991MKH 234 bp overlap

CHD7 2 datasets

ChIP H1 ENCFF126NLU 340 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 133 bp overlap

DPF2 3 datasets

ChIP BIN-67 GSE117734.DPF2.BIN-67 190 bp overlap

ChIP BIN-67_ctrl GSE117734.DPF2.BIN-67_ctrl 237 bp overlap

ChIP SCCOHT-1 GSE117734.DPF2.SCCOHT-1 175 bp overlap

DRAP1 1 dataset

ChIP GM12878 GSE97661.DRAP1.GM12878 208 bp overlap

EGR1 2 datasets

ChIP H1 ENCFF451BLH 173 bp overlap

ChIP WA01 ENCSR000BJA.EGR1.WA01 135 bp overlap

EHF 1 dataset

Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap

ELF1 1 dataset

Motif DE_12h DE_12h-ELF1_MA0473.4 9 bp overlap

ELF3 3 datasets

Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap

ChIP PDAC GSE64557.ELF3.PDAC 321 bp overlap

ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 301 bp overlap

EP300 2 datasets

ChIP H1 ENCFF927IYK 201 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 153 bp overlap

ERF::FOXO1 1 dataset

Motif DE_12h DE_12h-ERFFOXO1_MA1936.2 12 bp overlap

ETV1 1 dataset

Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap

ETV5::FIGLA 2 datasets

Motif DE_12h DE_12h-ETV5FIGLA_MA1945.2 14 bp overlap

Motif ES_0h ES_0h-ETV5FIGLA_MA1945.2 14 bp overlap

ETV7 1 dataset

Motif DE_12h DE_12h-ETV7_MA1708.2 9 bp overlap

Elf5 1 dataset

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

Erg 1 dataset

Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_12h DE_12h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXP1 1 dataset

ChIP LNCaP GSE62492.FOXP1.LNCaP 77 bp overlap

GABPA 2 datasets

Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap

ChIP WA01 ENCSR000BIW.GABPA.WA01 125 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000BNR.HDAC2.WA01 140 bp overlap

HOXB2::ELK1 1 dataset

Motif DE_12h DE_12h-HOXB2ELK1_MA1957.1 14 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

Ikzf3 1 dataset

Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap

JUND 2 datasets

ChIP H1 ENCFF468JZD 171 bp overlap

ChIP WA01 ENCSR000BKP.JUND.WA01 142 bp overlap

KLF10 2 datasets

ChIP HEK293 ENCFF326EGX 340 bp overlap

ChIP HEK293 ENCSR006GAQ.KLF10.HEK293 265 bp overlap

KLF9 1 dataset

ChIP GBM1A GSE62211.KLF9.GBM1A 122 bp overlap

MAX 2 datasets

ChIP P493-6 GSE36354.MAX.P493-6 162 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 137 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MEIS2 1 dataset

Motif DE_12h DE_12h-MEIS2_MA0774.1 8 bp overlap

MEIS3 1 dataset

Motif DE_12h DE_12h-MEIS3_MA0775.2 7 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 141 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 137 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 289 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 222 bp overlap

NFATC3 1 dataset

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

NKX2-1 1 dataset

ChIP NCI-H3122 GSE39998.NKX2-1.NCI-H3122 123 bp overlap

Nfatc1 1 dataset

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

PBX3 1 dataset

Motif DE_12h DE_12h-PBX3_MA1114.2 11 bp overlap

PKNOX1 1 dataset

Motif DE_12h DE_12h-PKNOX1_MA0782.3 10 bp overlap

POU5F1 2 datasets

ChIP WA01 ENCSR000BMU.POU5F1.WA01 143 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 185 bp overlap

PRDM15 3 datasets

ChIP Hep-G2 ENCSR011INW.PRDM15.Hep-G2 222 bp overlap

ChIP HepG2 ENCFF259LUZ 162 bp overlap

ChIP WTC11 ENCFF108TMF 199 bp overlap

Prdm15 1 dataset

Motif DE_12h DE_12h-Prdm15_MA1616.2 11 bp overlap

RAD21 1 dataset

ChIP HAP1 GSE152721.RAD21.HAP1 90 bp overlap

RELA 1 dataset

ChIP Detroit-562_Poly-I GSE91018.RELA.Detroit-562_Poly-I 233 bp overlap

RREB1 2 datasets

Motif DE_12h DE_12h-RREB1_MA0073.2 19 bp overlap

Motif ES_0h ES_0h-RREB1_MA0073.2 19 bp overlap

SIN3A 2 datasets

ChIP H1 ENCFF042ZSL 312 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 140 bp overlap

SMARCA4 4 datasets

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4 82 bp overlap

ChIP BT-16_Dox GSE71504.SMARCA4.BT-16_Dox 249 bp overlap

ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 144 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 71 bp overlap

SP1 5 datasets

ChIP A-549 ENCSR000BPE.SP1.A-549 164 bp overlap

ChIP H1 ENCFF263FUH 170 bp overlap

ChIP HCT-116 ENCSR000BSF.SP1.HCT-116 181 bp overlap

ChIP HCT116 ENCFF800LBN 261 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 249 bp overlap

SPI1 1 dataset

ChIP EM-3 GSE128834.SPI1.EM-3 158 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

TAF1 1 dataset

ChIP WA01 ENCSR000BHO.TAF1.WA01 118 bp overlap

TBP 1 dataset

ChIP hESC_8h GSE122298.TBP.hESC_8h 110 bp overlap

TBX5 2 datasets

Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap

Motif ES_0h ES_0h-TBX5_MA0807.1 8 bp overlap

TEAD1 1 dataset

ChIP HUCCT1 GSE68296.TEAD1.HUCCT1 215 bp overlap

TEAD4 2 datasets

ChIP H1 ENCFF778PAX 184 bp overlap

ChIP Ishikawa ENCSR000BSW.TEAD4.Ishikawa 126 bp overlap

YY1 4 datasets

ChIP H1 ENCFF524BTL 216 bp overlap

ChIP HCT-116 ENCSR000BNX.YY1.HCT-116 108 bp overlap

ChIP Ishikawa ENCSR000BSY.YY1.Ishikawa 95 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 160 bp overlap

ZBTB12 2 datasets

ChIP HEK293 ENCFF963HPT 331 bp overlap

ChIP HEK293 ENCSR543KOA.ZBTB12.HEK293 280 bp overlap

ZBTB18 1 dataset

Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap

ZNF175 1 dataset

Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap

ZNF189 2 datasets

Motif DE_12h DE_12h-ZNF189_MA1725.2 9 bp overlap

Motif ES_0h ES_0h-ZNF189_MA1725.2 9 bp overlap

ZNF282 2 datasets

Motif DE_12h DE_12h-ZNF282_MA1154.2 15 bp overlap

Motif ES_0h ES_0h-ZNF282_MA1154.2 15 bp overlap

ZNF580 1 dataset

ChIP HEK293 ENCSR668HOP.ZNF580.HEK293 230 bp overlap

ZNF610 2 datasets

ChIP HEK293 ENCFF778UKJ 309 bp overlap

ChIP HEK293 ENCSR691TXI.ZNF610.HEK293 306 bp overlap

ZSCAN31 2 datasets

Motif DE_12h DE_12h-ZSCAN31_MA1722.2 18 bp overlap

Motif ES_0h ES_0h-ZSCAN31_MA1722.2 18 bp overlap

ZXDB 1 dataset

ChIP HEK293 ENCSR559IOZ.ZXDB.HEK293 229 bp overlap