chr3 : 170,595,989 – 170,596,618

629 bp 95 TFs 1 linked gene

This 629 bp open chromatin element is linked to SLC7A14 and is bound by 95 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
SLC7A14		10.0 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

95 transcription factors

AR 1 dataset

ChIP 22Rv1_shKDM3A GSE109748.AR.22Rv1_shKDM3A 133 bp overlap

Arid3a 1 dataset

Motif DE_72h DE_72h-Arid3a_MA0151.1 6 bp overlap

Atf3 1 dataset

Motif DE_72h DE_72h-Atf3_MA1988.2 7 bp overlap

BACH1 1 dataset

Motif DE_72h DE_72h-BACH1_MA1633.2 9 bp overlap

BACH2 1 dataset

Motif DE_72h DE_72h-BACH2_MA1101.3 11 bp overlap

BATF 1 dataset

Motif DE_72h DE_72h-BATF_MA1634.2 7 bp overlap

BATF3 1 dataset

Motif DE_72h DE_72h-BATF3_MA0835.3 7 bp overlap

BATF::JUN 1 dataset

Motif DE_72h DE_72h-BATFJUN_MA0462.3 7 bp overlap

BNC2 1 dataset

Motif DE_72h DE_72h-BNC2_MA1928.2 7 bp overlap

DPF2 1 dataset

ChIP K-562 ENCSR219BXP.DPF2.K-562 195 bp overlap

ESR1 1 dataset

ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 91 bp overlap

ESRRA 1 dataset

ChIP SK-BR-3_EGF GSE81651.ESRRA.SK-BR-3_EGF 83 bp overlap

FIGLA 2 datasets

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOS 1 dataset

Motif DE_72h DE_72h-FOS_MA0476.2 8 bp overlap

FOS::JUN 1 dataset

Motif DE_72h DE_72h-FOSJUN_MA0099.4 9 bp overlap

FOS::JUNB 1 dataset

Motif DE_72h DE_72h-FOSJUNB_MA1134.2 9 bp overlap

FOS::JUND 1 dataset

Motif DE_72h DE_72h-FOSJUND_MA1141.2 9 bp overlap

FOSB::JUNB 1 dataset

Motif DE_72h DE_72h-FOSBJUNB_MA1135.2 9 bp overlap

FOSL1 1 dataset

Motif DE_72h DE_72h-FOSL1_MA0477.3 9 bp overlap

FOSL1::JUN 1 dataset

Motif DE_72h DE_72h-FOSL1JUN_MA1128.2 9 bp overlap

FOSL1::JUNB 1 dataset

Motif DE_72h DE_72h-FOSL1JUNB_MA1137.2 9 bp overlap

FOSL1::JUND 1 dataset

Motif DE_72h DE_72h-FOSL1JUND_MA1142.2 8 bp overlap

FOSL2 1 dataset

Motif DE_72h DE_72h-FOSL2_MA0478.2 10 bp overlap

FOSL2::JUN 1 dataset

Motif DE_72h DE_72h-FOSL2JUN_MA1130.2 9 bp overlap

FOSL2::JUNB 1 dataset

Motif DE_72h DE_72h-FOSL2JUNB_MA1138.2 9 bp overlap

FOSL2::JUND 1 dataset

Motif DE_72h DE_72h-FOSL2JUND_MA1144.2 9 bp overlap

FOXA1 4 datasets

ChIP ZR751_E2 GSE72249.FOXA1.ZR751_E2 149 bp overlap

ChIP ZR751_E2_TAM ERP000380.FOXA1.ZR751_E2_TAM 113 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 132 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 250 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 629 bp overlap

ChIP DE DE-FOXA2-2 629 bp overlap

GATA4 7 datasets

ChIP DE DE-GATA4-1 629 bp overlap

ChIP DE DE-GATA4-2 629 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 619 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 629 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 629 bp overlap

GATA6 10 datasets

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 153 bp overlap

ChIP DE DE-GATA6-1 629 bp overlap

ChIP DE DE-GATA6-2 629 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 338 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 419 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 273 bp overlap

ChIP foregut GSE117136.GATA6.foregut 581 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 629 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 437 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 531 bp overlap

HES6 1 dataset

Motif DE_72h DE_72h-HES6_MA1493.1 10 bp overlap

HNF4A 1 dataset

ChIP liver ENCFF354NRH 223 bp overlap

HOXA10 2 datasets

Motif DE_60h DE_60h-HOXA10_MA0899.2 9 bp overlap

Motif DE_72h DE_72h-HOXA10_MA0899.2 9 bp overlap

HOXD9 2 datasets

Motif DE_60h DE_60h-HOXD9_MA0913.3 9 bp overlap

Motif DE_72h DE_72h-HOXD9_MA0913.3 9 bp overlap

JDP2 1 dataset

Motif DE_72h DE_72h-JDP2_MA0655.1 9 bp overlap

JUN::JUNB 1 dataset

Motif DE_72h DE_72h-JUNJUNB_MA1132.2 8 bp overlap

JUNB 1 dataset

Motif DE_72h DE_72h-JUNB_MA0490.3 9 bp overlap

JUND 1 dataset

Motif DE_72h DE_72h-JUND_MA0491.3 9 bp overlap

Jun 1 dataset

Motif DE_72h DE_72h-Jun_MA0489.3 8 bp overlap

KDM1A 3 datasets

ChIP K-562 GSE117944.KDM1A.K-562 163 bp overlap

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 509 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 616 bp overlap

MAF 2 datasets

Motif DE_60h DE_60h-MAF_MA1520.2 13 bp overlap

Motif DE_72h DE_72h-MAF_MA1520.2 13 bp overlap

MAF::NFE2 1 dataset

Motif DE_72h DE_72h-MAFNFE2_MA0501.2 11 bp overlap

MAFA 2 datasets

Motif DE_60h DE_60h-MAFA_MA1521.2 13 bp overlap

Motif DE_72h DE_72h-MAFA_MA1521.2 13 bp overlap

MAFG::NFE2L1 1 dataset

Motif DE_72h DE_72h-MAFGNFE2L1_MA0089.3 11 bp overlap

MAFK 1 dataset

Motif DE_72h DE_72h-MAFK_MA0496.4 10 bp overlap

MITF 1 dataset

ChIP melanocyte_BRAFV600E GSE50681.MITF.melanocyte_BRAFV600E 210 bp overlap

MXI1 1 dataset

Motif DE_72h DE_72h-MXI1_MA1108.3 6 bp overlap

Mafg 2 datasets

Motif DE_72h DE_72h-Mafg_MA0659.4 12 bp overlap

NFATC3 1 dataset

Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap

NFE2 4 datasets

Motif DE_72h DE_72h-NFE2_MA0841.2 10 bp overlap

ChIP K-562 ENCSR552YGL.NFE2.K-562 199 bp overlap

ChIP K-562 ENCSR000FCC.NFE2.K-562 136 bp overlap

ChIP K562 ENCFF047YKA 363 bp overlap

NR1I2 1 dataset

Motif DE_72h DE_72h-NR1I2_MA1533.2 15 bp overlap

NR2C1 1 dataset

Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap

NR2F1 2 datasets

Motif DE_72h DE_72h-NR2F1_MA0017.3 12 bp overlap

Motif DE_72h DE_72h-NR2F1_MA1538.1 15 bp overlap

NR2F2 1 dataset

Motif DE_72h DE_72h-NR2F2_MA1111.2 7 bp overlap

NR2F6 1 dataset

Motif DE_72h DE_72h-NR2F6_MA1539.1 15 bp overlap

NR4A1 1 dataset

Motif DE_72h DE_72h-NR4A1_MA1112.3 8 bp overlap

NR4A2 1 dataset

Motif DE_72h DE_72h-NR4A2_MA0160.3 8 bp overlap

NRIP1 1 dataset

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 153 bp overlap

Nfat5 1 dataset

Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap

Nfatc1 1 dataset

Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 1 dataset

Motif DE_72h DE_72h-Nfatc2_MA0152.3 8 bp overlap

Nfe2l2 1 dataset

Motif DE_72h DE_72h-Nfe2l2_MA0150.3 11 bp overlap

Nr1H2 1 dataset

Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap

PDX1 1 dataset

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 434 bp overlap

PPARA::RXRA 1 dataset

Motif DE_72h DE_72h-PPARARXRA_MA1148.2 17 bp overlap

Ppara 1 dataset

Motif DE_72h DE_72h-Ppara_MA2338.1 7 bp overlap

Pparg::Rxra 1 dataset

Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap

RARA 1 dataset

Motif DE_72h DE_72h-RARA_MA0730.1 17 bp overlap

RARA::RXRG 1 dataset

Motif DE_72h DE_72h-RARARXRG_MA1149.2 17 bp overlap

RARG 1 dataset

Motif DE_72h DE_72h-RARG_MA1553.2 13 bp overlap

REST 2 datasets

ChIP LNCaP GSE119385.REST.LNCaP 275 bp overlap

ChIP colorectal-cancer_shCDH1 GSE112555.REST.colorectal-cancer_shCDH1 359 bp overlap

RXRA::VDR 1 dataset

Motif DE_72h DE_72h-RXRAVDR_MA0074.1 15 bp overlap

Rarb 1 dataset

Motif DE_72h DE_72h-Rarb_MA0858.1 17 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 469 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 251 bp overlap

SOX10 2 datasets

Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SPIC 2 datasets

Motif DE_60h DE_60h-SPIC_MA0687.2 13 bp overlap

Motif DE_72h DE_72h-SPIC_MA0687.2 13 bp overlap

Spi1 2 datasets

Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap

Motif DE_72h DE_72h-Spi1_MA0080.7 13 bp overlap

Stat2 2 datasets

Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap

Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap

TCF4 2 datasets

Motif DE_60h DE_60h-TCF4_MA0830.3 8 bp overlap

Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap

ZBTB24 1 dataset

Motif DE_72h DE_72h-ZBTB24_MA2330.1 10 bp overlap

ZEB1 2 datasets

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ZKSCAN1 3 datasets

Motif DE_72h DE_72h-ZKSCAN1_MA1585.2 9 bp overlap

ChIP K-562 ENCSR882ERE.ZKSCAN1.K-562 212 bp overlap

ChIP K562 ENCFF977CBA 259 bp overlap

ZNF329 2 datasets

ChIP HEK293 GSE76494.ZNF329.HEK293 160 bp overlap

ChIP HepG2 ENCFF057KSB 477 bp overlap

ZNF384 2 datasets

Motif DE_60h DE_60h-ZNF384_MA1125.2 8 bp overlap

Motif DE_72h DE_72h-ZNF384_MA1125.2 8 bp overlap

ZNF425 1 dataset

ChIP HEK293T GSE78099.ZNF425.HEK293T 190 bp overlap

ZNF507 1 dataset

ChIP K562 ENCFF577IRE 294 bp overlap

ZNF530 1 dataset

Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap

ZNF680 1 dataset

Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap

ZNF708 1 dataset

Motif DE_72h DE_72h-ZNF708_MA1730.2 9 bp overlap

ZSCAN16 2 datasets

Motif DE_60h DE_60h-ZSCAN16_MA2100.1 18 bp overlap

Motif DE_72h DE_72h-ZSCAN16_MA2100.1 18 bp overlap

Zfp335 1 dataset

Motif DE_72h DE_72h-Zfp335_MA2002.2 7 bp overlap