Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZNF329. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF329 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF329, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:57,410,944–57,411,658 | 744.0 kb | Distal (>10kb) Multiome HiCAR | 612 | |
| chr19:57,477,251–57,477,789 | 677.5 kb | Distal (>10kb) Multiome HiCAR | 582 | |
| chr19:57,487,570–57,488,036 | 667.3 kb | Distal (>10kb) Multiome HiCAR | 483 | |
| chr19:57,559,528–57,559,978 | 595.3 kb | Distal (>10kb) Multiome HiCAR | 564 | |
| chr19:57,578,473–57,579,216 | 576.1 kb | Distal (>10kb) Multiome HiCAR | 668 | |
| chr19:57,583,416–57,584,426 | 571.1 kb | Distal (>10kb) Multiome HiCAR | 462 | |
| chr19:57,614,049–57,614,534 | 540.9 kb | Distal (>10kb) Multiome HiCAR | 661 | |
| chr19:57,632,786–57,633,679 | 521.9 kb | Distal (>10kb) Multiome HiCAR | 652 | |
| chr19:57,708,682–57,709,450 | 445.9 kb | Distal (>10kb) Multiome HiCAR | 199 | |
| chr19:57,746,610–57,747,111 | 408.3 kb | Distal (>10kb) Multiome HiCAR | 625 | |
| chr19:57,887,264–57,887,897 | 267.5 kb | Distal (>10kb) Multiome | 47 | |
| chr19:57,888,389–57,889,457 | 266.1 kb | Distal (>10kb) Multiome | 322 | |
| chr19:57,916,199–57,917,124 | 238.4 kb | Distal (>10kb) Multiome | 535 | |
| chr19:57,934,907–57,935,617 | 219.8 kb | Distal (>10kb) Multiome HiCAR | 259 | |
| chr19:57,947,388–57,948,012 | 207.3 kb | Distal (>10kb) Multiome | 675 | |
| chr19:58,002,336–58,003,368 | 152.3 kb | Distal (>10kb) Multiome | 830 | |
| chr19:58,059,066–58,059,937 | 95.7 kb | Distal (>10kb) Multiome | 284 | |
| chr19:58,097,783–58,098,870 | 56.8 kb | Distal (>10kb) Multiome | 458 | |
| chr19:58,150,278–58,150,941 | 4.4 kb | Proximal (<10kb) Multiome | 533 | |
| chr19:58,154,448–58,155,527 | 5 bp | At TSS Multiome | 802 | |
| chr19:58,182,544–58,183,906 | 28.1 kb | Distal (>10kb) Multiome | 1019 | |
| chr19:58,228,362–58,229,199 | 73.8 kb | Distal (>10kb) Multiome | 706 | |
| chr19:58,278,271–58,279,774 | 123.7 kb | Distal (>10kb) Multiome | 950 | |
| chr19:58,304,887–58,305,868 | 150.2 kb | Distal (>10kb) Multiome | 858 | |
| chr19:58,326,789–58,327,710 | 171.9 kb | Distal (>10kb) Multiome | 985 | |
| chr19:58,347,086–58,347,987 | 192.5 kb | Distal (>10kb) Multiome | 467 | |
| chr19:58,356,174–58,356,775 | 201.4 kb | Distal (>10kb) Multiome | 101 | |
| chr19:58,361,859–58,363,243 | 207.7 kb | Distal (>10kb) Multiome | 972 | |
| chr19:58,380,269–58,381,636 | 226.0 kb | Distal (>10kb) Multiome | 1044 | |
| chr19:58,386,311–58,387,531 | 232.0 kb | Distal (>10kb) Multiome | 1010 | |
| chr19:58,395,438–58,396,606 | 240.6 kb | Distal (>10kb) Multiome | 448 | |
| chr19:58,400,803–58,401,800 | 246.3 kb | Distal (>10kb) Multiome | 728 | |
| chr19:58,408,032–58,409,025 | 253.4 kb | Distal (>10kb) Multiome | 854 | |
| chr19:58,451,175–58,452,075 | 296.4 kb | Distal (>10kb) Multiome | 702 |
Genomic view of the ZNF329 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.