chr3 : 146,058,150 – 146,058,951

801 bp 98 TFs 1 linked gene

This 801 bp open chromatin element is linked to ENSG00000261051 and is bound by 98 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000261051		2.7 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

98 transcription factors

ALX3 1 dataset

Motif DE_60h DE_60h-ALX3_MA0634.2 6 bp overlap

ARGFX 1 dataset

Motif DE_60h DE_60h-ARGFX_MA1463.2 8 bp overlap

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 526 bp overlap

Alx1 1 dataset

Motif DE_60h DE_60h-Alx1_MA0854.2 8 bp overlap

Arid3b 1 dataset

Motif DE_60h DE_60h-Arid3b_MA0601.2 7 bp overlap

CTCF 1 dataset

ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 218 bp overlap

DRGX 1 dataset

Motif DE_60h DE_60h-DRGX_MA1481.2 6 bp overlap

EMX1 1 dataset

Motif DE_60h DE_60h-EMX1_MA0612.3 6 bp overlap

EMX2 1 dataset

Motif DE_60h DE_60h-EMX2_MA0886.2 6 bp overlap

EN1 1 dataset

Motif DE_60h DE_60h-EN1_MA0027.3 6 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 558 bp overlap

EP300 1 dataset

ChIP fibroblast_proliferating GSE106146.EP300.fibroblast_proliferating 130 bp overlap

ESR1 1 dataset

ChIP MCF-7_ethanol_MKL1D200 GSE107476.ESR1.MCF-7_ethanol_MKL1D200 308 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 202 bp overlap

ESX1 1 dataset

Motif DE_60h DE_60h-ESX1_MA0644.3 7 bp overlap

EVX1 1 dataset

Motif DE_60h DE_60h-EVX1_MA0887.2 6 bp overlap

EVX2 1 dataset

Motif DE_60h DE_60h-EVX2_MA0888.2 6 bp overlap

FOSL2 2 datasets

ChIP Hep-G2 ENCSR000BHP.FOSL2.Hep-G2 144 bp overlap

ChIP Hep-G2 ENCSR000BHP.FOSL2.Hep-G2 133 bp overlap

FOXA2 5 datasets

ChIP Caco-2 GSE66218.FOXA2.Caco-2 125 bp overlap

ChIP DE DE-FOXA2-1 713 bp overlap

ChIP DE DE-FOXA2-2 801 bp overlap

ChIP PANC-1 GSE119930.FOXA2.PANC-1 226 bp overlap

ChIP PANC-1_HNF1B-OE GSE119930.FOXA2.PANC-1_HNF1B-OE 241 bp overlap

FOXF1 1 dataset

ChIP GIST-T1 GSE106624.FOXF1.GIST-T1 230 bp overlap

FOXP1 1 dataset

ChIP LNCaP GSE62492.FOXP1.LNCaP 106 bp overlap

GATA1 1 dataset

Motif DE_48h DE_48h-GATA1_MA0035.5 7 bp overlap

GATA1::TAL1 1 dataset

Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 1 dataset

Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap

GATA4 8 datasets

ChIP DE DE-GATA4-1 760 bp overlap

ChIP DE DE-GATA4-2 801 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

ChIP G296S GSE85628.GATA4.G296S 321 bp overlap

ChIP G296S_2 GSE85628.GATA4.G296S_2 321 bp overlap

ChIP foregut GSE117136.GATA4.foregut 561 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 613 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 260 bp overlap

GATA5 1 dataset

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

GATA6 15 datasets

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 102 bp overlap

ChIP DE DE-GATA6-1 794 bp overlap

ChIP DE DE-GATA6-2 801 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 568 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 665 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 543 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 760 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 736 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 664 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 709 bp overlap

ChIP foregut GSE117136.GATA6.foregut 593 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 459 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 335 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 231 bp overlap

GRHL2 1 dataset

Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap

GSX1 1 dataset

Motif DE_60h DE_60h-GSX1_MA0892.2 6 bp overlap

Gata3 1 dataset

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

HIF1A 1 dataset

ChIP NCI-H1299 GSE76770.HIF1A.NCI-H1299 181 bp overlap

HLF 1 dataset

ChIP HepG2 ENCFF854JLR 245 bp overlap

HNF1A 1 dataset

Motif DE_60h DE_60h-HNF1A_MA0046.3 13 bp overlap

HNF1B 1 dataset

Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap

HOXA1 1 dataset

Motif DE_60h DE_60h-HOXA1_MA1495.2 6 bp overlap

HOXA2 1 dataset

Motif DE_60h DE_60h-HOXA2_MA0900.3 6 bp overlap

HOXB2 1 dataset

Motif DE_60h DE_60h-HOXB2_MA0902.3 6 bp overlap

HOXB3 1 dataset

Motif DE_60h DE_60h-HOXB3_MA0903.2 6 bp overlap

HOXB5 1 dataset

Motif DE_60h DE_60h-HOXB5_MA0904.3 6 bp overlap

HOXC8 1 dataset

Motif DE_60h DE_60h-HOXC8_MA1505.2 6 bp overlap

IRF3 1 dataset

Motif DE_48h DE_48h-IRF3_MA1418.2 17 bp overlap

ISX 1 dataset

Motif DE_60h DE_60h-ISX_MA0654.2 6 bp overlap

LMX1A 1 dataset

Motif DE_60h DE_60h-LMX1A_MA0702.3 7 bp overlap

LMX1B 1 dataset

Motif DE_60h DE_60h-LMX1B_MA0703.3 8 bp overlap

Lhx3 1 dataset

Motif DE_60h DE_60h-Lhx3_MA0135.2 12 bp overlap

Lhx4 1 dataset

Motif DE_60h DE_60h-Lhx4_MA0704.2 6 bp overlap

Lhx8 1 dataset

Motif DE_60h DE_60h-Lhx8_MA0705.2 6 bp overlap

MAFF 1 dataset

Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap

MBD4 2 datasets

ChIP Hep-G2 ENCSR000BQW.MBD4.Hep-G2 162 bp overlap

ChIP Hep-G2 ENCSR000BQW.MBD4.Hep-G2 201 bp overlap

MIXL1 1 dataset

Motif DE_60h DE_60h-MIXL1_MA0662.2 6 bp overlap

MNX1 1 dataset

Motif DE_60h DE_60h-MNX1_MA0707.3 6 bp overlap

Mafb 1 dataset

Motif DE_60h DE_60h-Mafb_MA0117.3 11 bp overlap

Mecom 1 dataset

Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap

NKX2-5 2 datasets

ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 262 bp overlap

ChIP hESC_sc-14033 GSE89457.NKX2-5.hESC_sc-14033 205 bp overlap

NKX6-1 1 dataset

Motif DE_60h DE_60h-NKX6-1_MA0674.2 7 bp overlap

NKX6-2 1 dataset

Motif DE_60h DE_60h-NKX6-2_MA0675.2 6 bp overlap

NOTO 1 dataset

Motif DE_60h DE_60h-NOTO_MA0710.2 7 bp overlap

NR2C1 1 dataset

Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap

NR2F2 1 dataset

ChIP liver ENCSR168SMX.NR2F2.liver 172 bp overlap

NRL 1 dataset

Motif DE_60h DE_60h-NRL_MA0842.3 12 bp overlap

Nr1H2 1 dataset

Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap

PDX1 1 dataset

Motif DE_60h DE_60h-PDX1_MA0132.3 6 bp overlap

POLR2A 2 datasets

ChIP gastroesophageal sphincter ENCFF070PCA 279 bp overlap

ChIP gastroesophageal sphincter ENCFF070PCA 341 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_60h DE_60h-POU2F1SOX2_MA1962.1 17 bp overlap

POU6F1 1 dataset

Motif DE_60h DE_60h-POU6F1_MA0628.2 6 bp overlap

PPARG 1 dataset

ChIP Hep-G2 ENCSR130VQL.PPARG.Hep-G2 219 bp overlap

PRRX1 1 dataset

Motif DE_60h DE_60h-PRRX1_MA0716.2 6 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap

RAD21 2 datasets

ChIP HAP1 GSE152721.RAD21.HAP1 691 bp overlap

ChIP HAP1_clone25 GSE152721.RAD21.HAP1_clone25 182 bp overlap

RAX2 1 dataset

Motif DE_60h DE_60h-RAX2_MA0717.2 6 bp overlap

RELA 1 dataset

ChIP aortic-endothelial-cell_IL1B_D7 GSE139377.RELA.aortic-endothelial-cell_IL1B_D7 159 bp overlap

Rhox11 1 dataset

Motif DE_48h DE_48h-Rhox11_MA0629.2 9 bp overlap

SHOX 1 dataset

Motif DE_60h DE_60h-SHOX_MA0630.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 617 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 556 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 259 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 503 bp overlap

SOX2 2 datasets

ChIP HCC95 GSE137459.SOX2.HCC95 328 bp overlap

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 196 bp overlap

SUPT16H 2 datasets

ChIP hiF-T GSE98758.SUPT16H.hiF-T 170 bp overlap

ChIP hiF-T GSE98758.SUPT16H.hiF-T 426 bp overlap

Shox2 1 dataset

Motif DE_60h DE_60h-Shox2_MA0720.2 6 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 191 bp overlap

TCF7L2 1 dataset

Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap

THRB 1 dataset

Motif DE_48h DE_48h-THRB_MA1576.2 18 bp overlap

TLX2 1 dataset

Motif DE_60h DE_60h-TLX2_MA1577.2 6 bp overlap

TRPS1 1 dataset

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

UNCX 1 dataset

Motif DE_60h DE_60h-UNCX_MA0721.2 6 bp overlap

VAX1 1 dataset

Motif DE_60h DE_60h-VAX1_MA0722.2 7 bp overlap

VAX2 1 dataset

Motif DE_60h DE_60h-VAX2_MA0723.3 6 bp overlap

VSX1 1 dataset

Motif DE_60h DE_60h-VSX1_MA0725.2 7 bp overlap

VSX2 1 dataset

Motif DE_60h DE_60h-VSX2_MA0726.2 7 bp overlap

ZKSCAN1 1 dataset

Motif DE_48h DE_48h-ZKSCAN1_MA1585.2 9 bp overlap

ZNF135 1 dataset

Motif DE_48h DE_48h-ZNF135_MA1587.1 14 bp overlap

ZNF677 1 dataset

Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap

ZSCAN21 1 dataset

Motif DE_60h DE_60h-ZSCAN21_MA2336.1 7 bp overlap

Zfp335 1 dataset

Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap

mix-a 1 dataset

Motif DE_60h DE_60h-mix-a_MA0621.2 7 bp overlap