chr2 : 208,183,512 – 208,183,833

321 bp 67 TFs 1 linked gene

This 321 bp open chromatin element is linked to C2orf80 and is bound by 67 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
C2orf80		3.2 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

67 transcription factors

ARNT::HIF1A 2 datasets

Motif DE_12h DE_12h-ARNTHIF1A_MA0259.2 5 bp overlap

Motif ES_0h ES_0h-ARNTHIF1A_MA0259.2 5 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 316 bp overlap

ChIP H1 ENCFF399KAM 113 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 221 bp overlap

Ahr::Arnt 2 datasets

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

Motif ES_0h ES_0h-AhrArnt_MA0006.2 5 bp overlap

Atoh1 2 datasets

Motif DE_24h DE_24h-Atoh1_MA1467.3 7 bp overlap

Motif ES_0h ES_0h-Atoh1_MA1467.3 7 bp overlap

BCOR 1 dataset

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 189 bp overlap

CRY1 2 datasets

ChIP U2OS GSE130602.CRY1.U2OS 190 bp overlap

ChIP U2OS_DMSO GSE130506.CRY1.U2OS_DMSO 189 bp overlap

CTCF 7 datasets

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP H1 ENCFF230QSV 162 bp overlap

ChIP H9 ENCFF152GTF 302 bp overlap

ChIP HAP1_clone21_CTCF-TSS-CRISPR_2 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_2 179 bp overlap

ChIP OCI-Ly3 ENCSR756ZKG.CTCF.OCI-Ly3 288 bp overlap

ChIP WA01 ENCSR000DLK.CTCF.WA01 128 bp overlap

ChIP endodermal cell ENCFF471YCZ 142 bp overlap

CTCFL 2 datasets

Motif DE_12h DE_12h-CTCFL_MA1102.3 8 bp overlap

Motif ES_0h ES_0h-CTCFL_MA1102.3 8 bp overlap

E2F6 1 dataset

ChIP WA01 ENCSR000BSI.E2F6.WA01 156 bp overlap

EBF1 1 dataset

ChIP ASC GSE54889.EBF1.ASC 181 bp overlap

EPAS1 2 datasets

Motif DE_12h DE_12h-EPAS1_MA2325.1 9 bp overlap

Motif ES_0h ES_0h-EPAS1_MA2325.1 9 bp overlap

ETS1 1 dataset

ChIP GM23338 ENCFF701IZH 163 bp overlap

EZH2 2 datasets

ChIP DND41 ENCSR000ASW.EZH2.DND41 194 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 321 bp overlap

Elf5 2 datasets

Motif DE_24h DE_24h-Elf5_MA0136.4 8 bp overlap

Motif ES_0h ES_0h-Elf5_MA0136.4 8 bp overlap

GATA6 1 dataset

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 112 bp overlap

Gfi1B 2 datasets

Motif DE_24h DE_24h-Gfi1B_MA0483.2 10 bp overlap

Motif ES_0h ES_0h-Gfi1B_MA0483.2 10 bp overlap

HAND2 2 datasets

Motif DE_24h DE_24h-HAND2_MA1638.2 6 bp overlap

Motif ES_0h ES_0h-HAND2_MA1638.2 6 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 175 bp overlap

HIF1A 2 datasets

Motif DE_12h DE_12h-HIF1A_MA1106.2 6 bp overlap

Motif ES_0h ES_0h-HIF1A_MA1106.2 6 bp overlap

HOXC12 2 datasets

Motif DE_12h DE_12h-HOXC12_MA0906.2 10 bp overlap

Motif ES_0h ES_0h-HOXC12_MA0906.2 10 bp overlap

HOXD11 2 datasets

Motif DE_12h DE_12h-HOXD11_MA0908.2 9 bp overlap

Motif ES_0h ES_0h-HOXD11_MA0908.2 9 bp overlap

IKZF1 1 dataset

ChIP K-562 ENCSR395HWC.IKZF1.K-562 253 bp overlap

INSM1 2 datasets

Motif DE_12h DE_12h-INSM1_MA0155.1 12 bp overlap

Motif ES_0h ES_0h-INSM1_MA0155.1 12 bp overlap

ISL2 2 datasets

Motif DE_12h DE_12h-ISL2_MA0914.2 6 bp overlap

Motif ES_0h ES_0h-ISL2_MA0914.2 6 bp overlap

KLF1 1 dataset

Motif ES_0h ES_0h-KLF1_MA0493.3 8 bp overlap

KLF15 1 dataset

Motif ES_0h ES_0h-KLF15_MA1513.2 8 bp overlap

KLF2 1 dataset

Motif ES_0h ES_0h-KLF2_MA1515.2 8 bp overlap

KLF4 1 dataset

Motif ES_0h ES_0h-KLF4_MA0039.5 8 bp overlap

KLF7 1 dataset

Motif ES_0h ES_0h-KLF7_MA1959.2 8 bp overlap

MAFF 1 dataset

Motif DE_12h DE_12h-MAFF_MA0495.4 11 bp overlap

Mafb 1 dataset

Motif DE_12h DE_12h-Mafb_MA0117.3 11 bp overlap

NANOG 1 dataset

ChIP WA01 ERP004238.NANOG.WA01 177 bp overlap

NEUROD1 2 datasets

Motif DE_24h DE_24h-NEUROD1_MA1109.2 8 bp overlap

Motif ES_0h ES_0h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 2 datasets

Motif DE_24h DE_24h-NEUROG2_MA1642.2 7 bp overlap

Motif ES_0h ES_0h-NEUROG2_MA1642.2 7 bp overlap

Neurod2 2 datasets

Motif DE_24h DE_24h-Neurod2_MA0668.3 8 bp overlap

Motif ES_0h ES_0h-Neurod2_MA0668.3 8 bp overlap

PATZ1 1 dataset

Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 254 bp overlap

POU2F1 1 dataset

ChIP HepG2 ENCFF422JZU 321 bp overlap

POU5F1 1 dataset

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 103 bp overlap

Pparg::Rxra 2 datasets

Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap

Motif ES_0h ES_0h-PpargRxra_MA0065.3 13 bp overlap

Prdm5 2 datasets

Motif DE_24h DE_24h-Prdm5_MA1999.2 11 bp overlap

Motif ES_0h ES_0h-Prdm5_MA1999.2 11 bp overlap

Ptf1A 2 datasets

Motif DE_24h DE_24h-Ptf1A_MA1618.2 9 bp overlap

Motif ES_0h ES_0h-Ptf1A_MA1618.2 9 bp overlap

SIN3A 1 dataset

ChIP HUVEC-C GSE103245.SIN3A.HUVEC-C 157 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 102 bp overlap

SPI1 2 datasets

ChIP DC_96h_donorM GSE128834.SPI1.DC_96h_donorM 168 bp overlap

ChIP primary-neutrophil_donorF GSE128834.SPI1.primary-neutrophil_donorF 148 bp overlap

SPIC 2 datasets

Motif DE_24h DE_24h-SPIC_MA0687.2 13 bp overlap

Motif ES_0h ES_0h-SPIC_MA0687.2 13 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 145 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 62 bp overlap

Spi1 2 datasets

Motif DE_24h DE_24h-Spi1_MA0080.7 13 bp overlap

Motif ES_0h ES_0h-Spi1_MA0080.7 13 bp overlap

TBP 2 datasets

ChIP K-562 GSE55306.TBP.K-562 179 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 167 bp overlap

TBX20 2 datasets

Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap

Motif ES_0h ES_0h-TBX20_MA0689.1 11 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 192 bp overlap

ZBED4 1 dataset

Motif ES_0h ES_0h-ZBED4_MA2328.1 10 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 241 bp overlap

ZFP36 1 dataset

ChIP K-562 ENCSR776CYN.ZFP36.K-562 107 bp overlap

ZNF148 1 dataset

Motif ES_0h ES_0h-ZNF148_MA1653.2 10 bp overlap

ZNF184 2 datasets

Motif DE_12h DE_12h-ZNF184_MA2120.1 13 bp overlap

Motif ES_0h ES_0h-ZNF184_MA2120.1 13 bp overlap

ZNF257 1 dataset

ChIP HEK293T GSE78099.ZNF257.HEK293T 264 bp overlap

ZNF281 1 dataset

Motif ES_0h ES_0h-ZNF281_MA1630.3 10 bp overlap

ZNF320 2 datasets

Motif DE_12h DE_12h-ZNF320_MA1976.2 20 bp overlap

Motif ES_0h ES_0h-ZNF320_MA1976.2 20 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCFF896CCA 251 bp overlap

ZNF530 1 dataset

Motif ES_0h ES_0h-ZNF530_MA1981.2 14 bp overlap

ZNF610 1 dataset

Motif ES_0h ES_0h-ZNF610_MA1713.2 10 bp overlap

ZNF701 1 dataset

Motif ES_0h ES_0h-ZNF701_MA1987.2 17 bp overlap

ZNF75A 2 datasets

Motif DE_12h DE_12h-ZNF75A_MA2097.1 12 bp overlap

Motif ES_0h ES_0h-ZNF75A_MA2097.1 12 bp overlap

ZNF75D 2 datasets

Motif DE_12h DE_12h-ZNF75D_MA1601.2 12 bp overlap

Motif ES_0h ES_0h-ZNF75D_MA1601.2 12 bp overlap

ZNF823 1 dataset

ChIP HEK293T GSE78099.ZNF823.HEK293T 282 bp overlap