chr2 : 166,892,286 – 166,892,839
553 bp 118 TFs 1 linked gene
This 553 bp open chromatin element is linked to XIRP2 and is bound by 118 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
XIRP2 3.8 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:166,887,286 – 166,897,839
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
118 transcription factors
Source
Cell type
ASCL1 2 datasets
Motif DE_12h DE_12h-ASCL1_MA1631.2 9 bp overlap
Motif DE_24h DE_24h-ASCL1_MA1631.2 9 bp overlap
ATF2 1 dataset
ChIP WA01 ENCSR000BQU.ATF2.WA01 156 bp overlap
ATOH7 1 dataset
Motif DE_12h DE_12h-ATOH7_MA1468.1 10 bp overlap
CTNNB1 1 dataset
ChIP hESC_activinA_15h GSE99202.CTNNB1.hESC_activinA_15h 309 bp overlap
Ddit3::Cebpa 2 datasets
Motif DE_12h DE_12h-Ddit3Cebpa_MA0019.2 10 bp overlap
Motif DE_24h DE_24h-Ddit3Cebpa_MA0019.2 10 bp overlap
ERF 2 datasets
Motif DE_12h DE_12h-ERF_MA0760.2 9 bp overlap
Motif DE_24h DE_24h-ERF_MA0760.2 9 bp overlap
ERF::FOXI1 2 datasets
Motif DE_12h DE_12h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_24h DE_24h-ERFFOXI1_MA1935.2 10 bp overlap
ETS1 2 datasets
Motif DE_12h DE_12h-ETS1_MA0098.4 9 bp overlap
Motif DE_24h DE_24h-ETS1_MA0098.4 9 bp overlap
ETS2 2 datasets
Motif DE_12h DE_12h-ETS2_MA1484.2 9 bp overlap
Motif DE_24h DE_24h-ETS2_MA1484.2 9 bp overlap
ETV1 2 datasets
Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap
Motif DE_24h DE_24h-ETV1_MA0761.3 9 bp overlap
ETV2 2 datasets
Motif DE_12h DE_12h-ETV2_MA0762.2 9 bp overlap
Motif DE_24h DE_24h-ETV2_MA0762.2 9 bp overlap
ETV2::FOXI1 2 datasets
Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap
Motif DE_24h DE_24h-ETV2FOXI1_MA1942.2 11 bp overlap
Erg 2 datasets
Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap
Motif DE_24h DE_24h-Erg_MA0474.4 10 bp overlap
Esrrg 2 datasets
Motif DE_12h DE_12h-Esrrg_MA0643.2 9 bp overlap
Motif DE_24h DE_24h-Esrrg_MA0643.2 9 bp overlap
FIGLA 2 datasets
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap
FLI1::FOXI1 2 datasets
Motif DE_12h DE_12h-FLI1FOXI1_MA1950.2 11 bp overlap
Motif DE_24h DE_24h-FLI1FOXI1_MA1950.2 11 bp overlap
FOXA1 3 datasets
Motif DE_12h DE_12h-FOXA1_MA0148.5 8 bp overlap
ChIP HEK293_i176m_TFS GSE123618.FOXA1.HEK293_i176m_TFS 105 bp overlap
ChIP HEK293_r261g_TFS GSE123618.FOXA1.HEK293_r261g_TFS 138 bp overlap
FOXD3 1 dataset
Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap
FOXJ2::ELF1 2 datasets
Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap
Motif DE_24h DE_24h-FOXJ2ELF1_MA1952.2 11 bp overlap
FOXO1::ELF1 2 datasets
Motif DE_12h DE_12h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_24h DE_24h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::ELK1 2 datasets
Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_24h DE_24h-FOXO1ELK1_MA1954.2 13 bp overlap
FOXO1::FLI1 2 datasets
Motif DE_12h DE_12h-FOXO1FLI1_MA1956.2 13 bp overlap
Motif DE_24h DE_24h-FOXO1FLI1_MA1956.2 13 bp overlap
FOXP2 1 dataset
Motif DE_12h DE_12h-FOXP2_MA0593.2 9 bp overlap
Foxl2 1 dataset
Motif DE_12h DE_12h-Foxl2_MA1607.2 10 bp overlap
GABPA 2 datasets
Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap
Motif DE_24h DE_24h-GABPA_MA0062.4 10 bp overlap
GATA6 4 datasets
ChIP DE_D1 S09-DE-d1-GATA6-exp1 275 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 281 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 355 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 341 bp overlap
GFI1 3 datasets
Motif DE_12h DE_12h-GFI1_MA0038.3 11 bp overlap
Motif DE_12h DE_12h-GFI1_MA0038.3 11 bp overlap
Motif DE_12h DE_12h-GFI1_MA0038.3 11 bp overlap
Gfi1B 1 dataset
Motif DE_12h DE_12h-Gfi1B_MA0483.2 10 bp overlap
HAND2 2 datasets
Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap
Motif DE_24h DE_24h-HAND2_MA1638.2 6 bp overlap
Hand1 1 dataset
Motif DE_12h DE_12h-Hand1_MA2123.1 9 bp overlap
Hand1::Tcf3 1 dataset
Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap
Hmga1 1 dataset
Motif DE_12h DE_12h-Hmga1_MA2124.1 8 bp overlap
Hmx3 1 dataset
Motif DE_12h DE_12h-Hmx3_MA0898.2 9 bp overlap
Hnf1A 2 datasets
Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap
Hoxd13 2 datasets
Motif DE_12h DE_12h-Hoxd13_MA0909.4 7 bp overlap
Motif DE_24h DE_24h-Hoxd13_MA0909.4 7 bp overlap
IKZF1 2 datasets
Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap
Motif DE_24h DE_24h-IKZF1_MA1508.2 8 bp overlap
IKZF2 2 datasets
Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap
Motif DE_24h DE_24h-IKZF2_MA2326.1 6 bp overlap
Ikzf3 2 datasets
Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_24h DE_24h-Ikzf3_MA1992.2 9 bp overlap
JUN 3 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 354 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 286 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 358 bp overlap
KLF11 1 dataset
Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap
KLF6 1 dataset
Motif DE_12h DE_12h-KLF6_MA1517.2 9 bp overlap
KLF9 1 dataset
Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap
LEF1 1 dataset
ChIP hESC_WNT3A GSE64758.LEF1.hESC_WNT3A 281 bp overlap
Lef1 1 dataset
Motif DE_12h DE_12h-Lef1_MA0768.3 8 bp overlap
MAFF 1 dataset
Motif DE_12h DE_12h-MAFF_MA0495.4 11 bp overlap
MXI1 1 dataset
Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap
NANOG 6 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 432 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 308 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 372 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 339 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 371 bp overlap
ChIP hESC GSE18292.NANOG.hESC 190 bp overlap
NEUROG1 1 dataset
Motif DE_12h DE_12h-NEUROG1_MA0623.2 10 bp overlap
NEUROG2 1 dataset
Motif DE_12h DE_12h-NEUROG2_MA0669.1 10 bp overlap
NFIL3 2 datasets
Motif DE_12h DE_12h-NFIL3_MA0025.3 9 bp overlap
Motif DE_24h DE_24h-NFIL3_MA0025.3 9 bp overlap
NIPBL 2 datasets
ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 300 bp overlap
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 275 bp overlap
NR4A1 2 datasets
Motif DE_12h DE_12h-NR4A1_MA1112.3 8 bp overlap
Motif DE_12h DE_12h-NR4A1_MA1112.3 8 bp overlap
NR5A1 1 dataset
Motif DE_12h DE_12h-NR5A1_MA1540.3 12 bp overlap
NR6A1 1 dataset
Motif DE_12h DE_12h-NR6A1_MA1541.2 14 bp overlap
Nfat5 1 dataset
Motif DE_12h DE_12h-Nfat5_MA0606.3 8 bp overlap
Nr2e1 1 dataset
Motif DE_12h DE_12h-Nr2e1_MA0676.1 9 bp overlap
PAX6 1 dataset
Motif DE_12h DE_12h-PAX6_MA0069.1 14 bp overlap
POU2F1::SOX2 1 dataset
Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap
POU5F1 3 datasets
ChIP HUES-8 GSE109524.POU5F1.HUES-8 401 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 353 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 228 bp overlap
Pgr 1 dataset
Motif DE_12h DE_12h-Pgr_MA2323.1 17 bp overlap
Pou5f1::Sox2 1 dataset
Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap
RBPJ 3 datasets
Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap
Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap
Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap
SIX1 1 dataset
Motif DE_12h DE_12h-SIX1_MA1118.2 9 bp overlap
SIX2 1 dataset
Motif DE_12h DE_12h-SIX2_MA1119.2 11 bp overlap
SMAD2 1 dataset
Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 461 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 390 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 288 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 386 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 335 bp overlap
SMARCA4 2 datasets
ChIP hiPSC GSE124903.SMARCA4.hiPSC 242 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 243 bp overlap
SMARCB1 1 dataset
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 170 bp overlap
SMARCC1 3 datasets
ChIP DE_D1 S10-DE-d1-BAF155-exp1 288 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 267 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 294 bp overlap
SNAI1 2 datasets
Motif DE_12h DE_12h-SNAI1_MA1558.2 7 bp overlap
Motif DE_24h DE_24h-SNAI1_MA1558.2 7 bp overlap
SNAI3 2 datasets
Motif DE_12h DE_12h-SNAI3_MA1559.2 9 bp overlap
Motif DE_24h DE_24h-SNAI3_MA1559.2 9 bp overlap
SOX10 1 dataset
Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap
SOX13 1 dataset
Motif DE_12h DE_12h-SOX13_MA1120.2 7 bp overlap
SOX2 1 dataset
Motif DE_12h DE_12h-SOX2_MA0143.5 7 bp overlap
SOX4 1 dataset
Motif DE_12h DE_12h-SOX4_MA0867.3 8 bp overlap
SOX8 1 dataset
Motif DE_12h DE_12h-SOX8_MA0868.3 7 bp overlap
SOX9 1 dataset
Motif DE_12h DE_12h-SOX9_MA0077.2 8 bp overlap
SP8 1 dataset
Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap
SRY 1 dataset
Motif DE_12h DE_12h-SRY_MA0084.2 7 bp overlap
Six4 1 dataset
Motif DE_12h DE_12h-Six4_MA2001.2 7 bp overlap
Sox1 1 dataset
Motif DE_12h DE_12h-Sox1_MA0870.1 15 bp overlap
Sox17 1 dataset
Motif DE_12h DE_12h-Sox17_MA0078.3 10 bp overlap
Sox3 1 dataset
Motif DE_12h DE_12h-Sox3_MA0514.3 7 bp overlap
Sox5 1 dataset
Motif DE_12h DE_12h-Sox5_MA0087.3 8 bp overlap
Sox6 1 dataset
Motif DE_12h DE_12h-Sox6_MA0515.1 10 bp overlap
Sox7 1 dataset
Motif DE_12h DE_12h-Sox7_MA2095.1 10 bp overlap
Stat5a::Stat5b 1 dataset
Motif DE_12h DE_12h-Stat5aStat5b_MA0519.2 9 bp overlap
Stat5b 2 datasets
Motif DE_12h DE_12h-Stat5b_MA1625.2 9 bp overlap
Motif DE_12h DE_12h-Stat5b_MA1625.2 9 bp overlap
Stat6 3 datasets
Motif DE_12h DE_12h-Stat6_MA0520.2 10 bp overlap
Motif DE_12h DE_12h-Stat6_MA0520.2 10 bp overlap
Motif DE_24h DE_24h-Stat6_MA0520.2 10 bp overlap
T 1 dataset
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 183 bp overlap
TCF12 2 datasets
Motif DE_12h DE_12h-TCF12_MA1648.2 7 bp overlap
Motif DE_24h DE_24h-TCF12_MA1648.2 7 bp overlap
TCF3 2 datasets
Motif DE_12h DE_12h-TCF3_MA0522.4 7 bp overlap
Motif DE_24h DE_24h-TCF3_MA0522.4 7 bp overlap
TCF7 1 dataset
Motif DE_12h DE_12h-TCF7_MA0769.3 7 bp overlap
TCF7L2 2 datasets
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
TFAP4 1 dataset
Motif DE_12h DE_12h-TFAP4_MA1570.1 10 bp overlap
ZBTB24 2 datasets
Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap
Motif DE_24h DE_24h-ZBTB24_MA2330.1 10 bp overlap
ZEB1 2 datasets
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap
ZIC1 1 dataset
Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap
ZNF143 1 dataset
Motif DE_12h DE_12h-ZNF143_MA0088.2 16 bp overlap
ZNF175 2 datasets
Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap
Motif DE_24h DE_24h-ZNF175_MA2332.1 9 bp overlap
ZNF257 2 datasets
Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap
Motif DE_24h DE_24h-ZNF257_MA1710.2 10 bp overlap
ZNF274 1 dataset
Motif DE_12h DE_12h-ZNF274_MA1592.2 12 bp overlap
ZNF282 1 dataset
Motif DE_12h DE_12h-ZNF282_MA1154.2 15 bp overlap
ZNF331 2 datasets
Motif DE_12h DE_12h-ZNF331_MA1726.2 10 bp overlap
Motif DE_24h DE_24h-ZNF331_MA1726.2 10 bp overlap
ZNF382 1 dataset
Motif DE_12h DE_12h-ZNF382_MA1594.1 24 bp overlap
ZNF454 1 dataset
Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap
ZNF558 1 dataset
Motif DE_12h DE_12h-ZNF558_MA2335.1 29 bp overlap
ZNF677 1 dataset
Motif DE_12h DE_12h-ZNF677_MA2101.1 12 bp overlap
ZNF76 1 dataset
Motif DE_12h DE_12h-ZNF76_MA1716.2 17 bp overlap
ZNF816 2 datasets
Motif DE_12h DE_12h-ZNF816_MA1719.2 15 bp overlap
Motif DE_24h DE_24h-ZNF816_MA1719.2 15 bp overlap
ZNF85 1 dataset
Motif DE_12h DE_12h-ZNF85_MA1720.2 12 bp overlap
ZSCAN16 1 dataset
Motif DE_12h DE_12h-ZSCAN16_MA2100.1 18 bp overlap
ZSCAN31 1 dataset
Motif DE_12h DE_12h-ZSCAN31_MA1722.2 18 bp overlap
Zfp335 2 datasets
Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap
Motif DE_24h DE_24h-Zfp335_MA2002.2 7 bp overlap
Zic1::Zic2 1 dataset
Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap
Zic2 2 datasets
Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap
Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap
Zic3 1 dataset
Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap
Huangfu Lab · Publications · Resources · Contact