chr2 : 58,312,368 – 58,313,254
886 bp 66 TFs 4 linked genes
This 886 bp open chromatin element is linked to 4 target genes and is bound by 66 transcription factors.
Linked Genes
4 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
FANCL 71.5 kb Distal Multiome
LINC01122 115.6 kb Distal Multiome
ENSG00000289529 166.9 kb Distal Multiome
VRK2 266.0 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:58,307,368 – 58,318,254
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
66 transcription factors
Source
Cell type
ASCL1 4 datasets
Motif DE_36h DE_36h-ASCL1_MA1631.2 9 bp overlap
Motif DE_48h DE_48h-ASCL1_MA1631.2 9 bp overlap
Motif DE_60h DE_60h-ASCL1_MA1631.2 9 bp overlap
Motif DE_72h DE_72h-ASCL1_MA1631.2 9 bp overlap
ATF3 4 datasets
Motif DE_36h DE_36h-ATF3_MA0605.3 10 bp overlap
Motif DE_48h DE_48h-ATF3_MA0605.3 10 bp overlap
Motif DE_60h DE_60h-ATF3_MA0605.3 10 bp overlap
Motif DE_72h DE_72h-ATF3_MA0605.3 10 bp overlap
ATF6 4 datasets
Motif DE_36h DE_36h-ATF6_MA1466.2 13 bp overlap
Motif DE_48h DE_48h-ATF6_MA1466.2 13 bp overlap
Motif DE_60h DE_60h-ATF6_MA1466.2 13 bp overlap
Motif DE_72h DE_72h-ATF6_MA1466.2 13 bp overlap
ATF7 4 datasets
Motif DE_36h DE_36h-ATF7_MA0834.2 10 bp overlap
Motif DE_48h DE_48h-ATF7_MA0834.2 10 bp overlap
Motif DE_60h DE_60h-ATF7_MA0834.2 10 bp overlap
Motif DE_72h DE_72h-ATF7_MA0834.2 10 bp overlap
Atf1 4 datasets
Motif DE_36h DE_36h-Atf1_MA0604.1 8 bp overlap
Motif DE_48h DE_48h-Atf1_MA0604.1 8 bp overlap
Motif DE_60h DE_60h-Atf1_MA0604.1 8 bp overlap
Motif DE_72h DE_72h-Atf1_MA0604.1 8 bp overlap
BARX2 3 datasets
Motif DE_36h DE_36h-BARX2_MA1471.2 9 bp overlap
Motif DE_48h DE_48h-BARX2_MA1471.2 9 bp overlap
Motif DE_60h DE_60h-BARX2_MA1471.2 9 bp overlap
BRD4 1 dataset
ChIP NMC24335 GSE96775.BRD4.NMC24335 423 bp overlap
CREB3 4 datasets
Motif DE_36h DE_36h-CREB3_MA0638.2 12 bp overlap
Motif DE_48h DE_48h-CREB3_MA0638.2 12 bp overlap
Motif DE_60h DE_60h-CREB3_MA0638.2 12 bp overlap
Motif DE_72h DE_72h-CREB3_MA0638.2 12 bp overlap
CREM 4 datasets
Motif DE_36h DE_36h-CREM_MA0609.3 10 bp overlap
Motif DE_48h DE_48h-CREM_MA0609.3 10 bp overlap
Motif DE_60h DE_60h-CREM_MA0609.3 10 bp overlap
Motif DE_72h DE_72h-CREM_MA0609.3 10 bp overlap
CUX1 1 dataset
Motif DE_48h DE_48h-CUX1_MA0754.3 9 bp overlap
CUX2 1 dataset
Motif DE_48h DE_48h-CUX2_MA0755.2 9 bp overlap
Creb5 4 datasets
Motif DE_36h DE_36h-Creb5_MA0840.2 10 bp overlap
Motif DE_48h DE_48h-Creb5_MA0840.2 10 bp overlap
Motif DE_60h DE_60h-Creb5_MA0840.2 10 bp overlap
Motif DE_72h DE_72h-Creb5_MA0840.2 10 bp overlap
DPRX 1 dataset
Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 316 bp overlap
ETV5::FIGLA 2 datasets
Motif DE_48h DE_48h-ETV5FIGLA_MA1945.2 14 bp overlap
Motif DE_60h DE_60h-ETV5FIGLA_MA1945.2 14 bp overlap
FIGLA 4 datasets
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOS::JUN 4 datasets
Motif DE_36h DE_36h-FOSJUN_MA1126.2 10 bp overlap
Motif DE_48h DE_48h-FOSJUN_MA1126.2 10 bp overlap
Motif DE_60h DE_60h-FOSJUN_MA1126.2 10 bp overlap
Motif DE_72h DE_72h-FOSJUN_MA1126.2 10 bp overlap
FOSB::JUN 4 datasets
Motif DE_36h DE_36h-FOSBJUN_MA1127.1 11 bp overlap
Motif DE_48h DE_48h-FOSBJUN_MA1127.1 11 bp overlap
Motif DE_60h DE_60h-FOSBJUN_MA1127.1 11 bp overlap
Motif DE_72h DE_72h-FOSBJUN_MA1127.1 11 bp overlap
FOSB::JUNB 4 datasets
Motif DE_36h DE_36h-FOSBJUNB_MA1136.1 10 bp overlap
Motif DE_48h DE_48h-FOSBJUNB_MA1136.1 10 bp overlap
Motif DE_60h DE_60h-FOSBJUNB_MA1136.1 10 bp overlap
Motif DE_72h DE_72h-FOSBJUNB_MA1136.1 10 bp overlap
FOSL1::JUND 4 datasets
Motif DE_36h DE_36h-FOSL1JUND_MA1143.2 9 bp overlap
Motif DE_48h DE_48h-FOSL1JUND_MA1143.2 9 bp overlap
Motif DE_60h DE_60h-FOSL1JUND_MA1143.2 9 bp overlap
Motif DE_72h DE_72h-FOSL1JUND_MA1143.2 9 bp overlap
FOSL2::JUND 4 datasets
Motif DE_36h DE_36h-FOSL2JUND_MA1145.2 10 bp overlap
Motif DE_48h DE_48h-FOSL2JUND_MA1145.2 10 bp overlap
Motif DE_60h DE_60h-FOSL2JUND_MA1145.2 10 bp overlap
Motif DE_72h DE_72h-FOSL2JUND_MA1145.2 10 bp overlap
FOXA1 1 dataset
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 300 bp overlap
FOXA2 3 datasets
ChIP DE DE-FOXA2-1 512 bp overlap
ChIP DE DE-FOXA2-2 542 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 297 bp overlap
GATA1 1 dataset
Motif DE_48h DE_48h-GATA1_MA0035.5 7 bp overlap
GATA1::TAL1 2 datasets
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 2 datasets
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 607 bp overlap
ChIP DE DE-GATA4-2 704 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 324 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 426 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 490 bp overlap
GATA5 2 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 17 datasets
ChIP AGS GSE51705.GATA6.AGS 283 bp overlap
ChIP DE DE-GATA6-1 568 bp overlap
ChIP DE DE-GATA6-2 751 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 572 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 639 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 783 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 549 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 601 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 534 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 511 bp overlap
ChIP foregut GSE117136.GATA6.foregut 262 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 276 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 269 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 452 bp overlap
Gata3 3 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Hand1 2 datasets
Motif DE_48h DE_48h-Hand1_MA2123.1 9 bp overlap
Motif DE_60h DE_60h-Hand1_MA2123.1 9 bp overlap
JDP2 4 datasets
Motif DE_36h DE_36h-JDP2_MA0656.2 10 bp overlap
Motif DE_48h DE_48h-JDP2_MA0656.2 10 bp overlap
Motif DE_60h DE_60h-JDP2_MA0656.2 10 bp overlap
Motif DE_72h DE_72h-JDP2_MA0656.2 10 bp overlap
JUN 2 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 253 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 371 bp overlap
JUN::JUNB 4 datasets
Motif DE_36h DE_36h-JUNJUNB_MA1133.2 11 bp overlap
Motif DE_48h DE_48h-JUNJUNB_MA1133.2 11 bp overlap
Motif DE_60h DE_60h-JUNJUNB_MA1133.2 11 bp overlap
Motif DE_72h DE_72h-JUNJUNB_MA1133.2 11 bp overlap
JUNB 4 datasets
Motif DE_36h DE_36h-JUNB_MA1140.3 11 bp overlap
Motif DE_48h DE_48h-JUNB_MA1140.3 11 bp overlap
Motif DE_60h DE_60h-JUNB_MA1140.3 11 bp overlap
Motif DE_72h DE_72h-JUNB_MA1140.3 11 bp overlap
LIN54 2 datasets
Motif DE_36h DE_36h-LIN54_MA0619.2 7 bp overlap
Motif DE_48h DE_48h-LIN54_MA0619.2 7 bp overlap
MEF2C 1 dataset
Motif DE_48h DE_48h-MEF2C_MA0497.2 11 bp overlap
Mecom 2 datasets
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Msgn1 3 datasets
Motif DE_36h DE_36h-Msgn1_MA1524.3 10 bp overlap
Motif DE_48h DE_48h-Msgn1_MA1524.3 10 bp overlap
Motif DE_60h DE_60h-Msgn1_MA1524.3 10 bp overlap
ONECUT1 3 datasets
Motif DE_48h DE_48h-ONECUT1_MA0679.3 9 bp overlap
ChIP H9 ERP004206.ONECUT1.H9 247 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 480 bp overlap
ONECUT2 2 datasets
ChIP AGS_Overexpression GSE113045.ONECUT2.AGS_Overexpression 307 bp overlap
Motif DE_48h DE_48h-ONECUT2_MA0756.3 8 bp overlap
PLAG1 3 datasets
Motif DE_48h DE_48h-PLAG1_MA0163.1 14 bp overlap
Motif DE_60h DE_60h-PLAG1_MA0163.1 14 bp overlap
Motif DE_72h DE_72h-PLAG1_MA0163.1 14 bp overlap
PPARA::RXRA 2 datasets
Motif DE_48h DE_48h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_60h DE_60h-PPARARXRA_MA1148.2 17 bp overlap
PROX1 4 datasets
Motif DE_36h DE_36h-PROX1_MA0794.1 12 bp overlap
Motif DE_48h DE_48h-PROX1_MA0794.1 12 bp overlap
Motif DE_60h DE_60h-PROX1_MA0794.1 12 bp overlap
Motif DE_72h DE_72h-PROX1_MA0794.1 12 bp overlap
SMAD2 3 datasets
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 202 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 586 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 603 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 541 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 640 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 575 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 605 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 670 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 667 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 174 bp overlap
SNAI1 4 datasets
Motif DE_36h DE_36h-SNAI1_MA1558.2 7 bp overlap
Motif DE_48h DE_48h-SNAI1_MA1558.2 7 bp overlap
Motif DE_60h DE_60h-SNAI1_MA1558.2 7 bp overlap
Motif DE_72h DE_72h-SNAI1_MA1558.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 412 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 466 bp overlap
TCF12 4 datasets
Motif DE_36h DE_36h-TCF12_MA1648.2 7 bp overlap
Motif DE_48h DE_48h-TCF12_MA1648.2 7 bp overlap
Motif DE_60h DE_60h-TCF12_MA1648.2 7 bp overlap
Motif DE_72h DE_72h-TCF12_MA1648.2 7 bp overlap
TCF3 4 datasets
Motif DE_36h DE_36h-TCF3_MA0522.4 7 bp overlap
Motif DE_48h DE_48h-TCF3_MA0522.4 7 bp overlap
Motif DE_60h DE_60h-TCF3_MA0522.4 7 bp overlap
Motif DE_72h DE_72h-TCF3_MA0522.4 7 bp overlap
TCF4 4 datasets
Motif DE_36h DE_36h-TCF4_MA0830.3 8 bp overlap
Motif DE_48h DE_48h-TCF4_MA0830.3 8 bp overlap
Motif DE_60h DE_60h-TCF4_MA0830.3 8 bp overlap
Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap
TEAD1 2 datasets
Motif DE_48h DE_48h-TEAD1_MA0090.4 9 bp overlap
Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap
TEAD2 2 datasets
Motif DE_48h DE_48h-TEAD2_MA1121.2 7 bp overlap
Motif DE_60h DE_60h-TEAD2_MA1121.2 7 bp overlap
TEAD3 2 datasets
Motif DE_48h DE_48h-TEAD3_MA0808.1 8 bp overlap
Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap
TEAD4 2 datasets
Motif DE_48h DE_48h-TEAD4_MA0809.3 8 bp overlap
Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap
TRPS1 3 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
XBP1 4 datasets
Motif DE_36h DE_36h-XBP1_MA0844.2 11 bp overlap
Motif DE_48h DE_48h-XBP1_MA0844.2 11 bp overlap
Motif DE_60h DE_60h-XBP1_MA0844.2 11 bp overlap
Motif DE_72h DE_72h-XBP1_MA0844.2 11 bp overlap
ZEB1 4 datasets
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZNF136 2 datasets
Motif DE_36h DE_36h-ZNF136_MA1588.1 15 bp overlap
Motif DE_48h DE_48h-ZNF136_MA1588.1 15 bp overlap
ZNF320 3 datasets
Motif DE_48h DE_48h-ZNF320_MA1976.2 20 bp overlap
Motif DE_60h DE_60h-ZNF320_MA1976.2 20 bp overlap
Motif DE_72h DE_72h-ZNF320_MA1976.2 20 bp overlap
ZNF354A 2 datasets
Motif DE_36h DE_36h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
ZNF384 1 dataset
Motif DE_48h DE_48h-ZNF384_MA1125.2 8 bp overlap
ZNF532 1 dataset
ChIP NMC24335 GSE96775.ZNF532.NMC24335 309 bp overlap
Huangfu Lab · Publications · Resources · Contact