chr2 : 44,166,185 – 44,166,382

197 bp 81 TFs 4 linked genes

This 197 bp open chromatin element is linked to 4 target genes and is bound by 81 transcription factors.

Linked Genes

4 genes

Gene	Dist. to TSS	Distance	Link type
PDSS1P2	at TSS	At TSS	Proximity
ENSG00000285542	2.5 kb	Proximal	Proximity
PPM1B-DT	2.5 kb	Proximal	Proximity
PPM1B	2.5 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

81 transcription factors

AGO2 2 datasets

ChIP HepG2 ENCFF252VFI 197 bp overlap

ChIP HepG2 ENCFF773YDL 197 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 197 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 197 bp overlap

ATF2 1 dataset

ChIP WA01 ENCSR000BQU.ATF2.WA01 141 bp overlap

Ahr::Arnt 2 datasets

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap

BRD4 1 dataset

ChIP hESC GSE33281.BRD4.hESC 79 bp overlap

CBFB 1 dataset

ChIP ME-1 GSE46044.CBFB.ME-1 197 bp overlap

CBX2 1 dataset

ChIP HEK293T GSE34774.CBX2.HEK293T 196 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 125 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 155 bp overlap

E2F6 1 dataset

ChIP WA01 ENCSR000BSI.E2F6.WA01 186 bp overlap

EGR1 1 dataset

Motif DE_12h DE_12h-EGR1_MA0162.5 10 bp overlap

ELK1::HOXA1 1 dataset

Motif DE_12h DE_12h-ELK1HOXA1_MA1931.1 14 bp overlap

ERG 1 dataset

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 197 bp overlap

ESR1 1 dataset

ChIP Ishikawa GSE99905.ESR1.Ishikawa 197 bp overlap

ETV5::DRGX 1 dataset

Motif DE_12h DE_12h-ETV5DRGX_MA1944.2 12 bp overlap

ETV7 1 dataset

Motif DE_12h DE_12h-ETV7_MA1708.2 9 bp overlap

FLI1 1 dataset

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 197 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 197 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 190 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 195 bp overlap

HOXB2::ELK1 1 dataset

Motif DE_12h DE_12h-HOXB2ELK1_MA1957.1 14 bp overlap

IRF3 2 datasets

Motif DE_12h DE_12h-IRF3_MA1418.2 17 bp overlap

Motif DE_24h DE_24h-IRF3_MA1418.2 17 bp overlap

IRF8 2 datasets

Motif DE_12h DE_12h-IRF8_MA0652.2 13 bp overlap

Motif DE_24h DE_24h-IRF8_MA0652.2 13 bp overlap

Irf1 2 datasets

Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap

Motif DE_24h DE_24h-Irf1_MA0050.4 11 bp overlap

JUN 4 datasets

Motif DE_12h DE_12h-JUN_MA0488.2 10 bp overlap

Motif DE_24h DE_24h-JUN_MA0488.2 10 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 197 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 197 bp overlap

JUND 2 datasets

Motif DE_12h DE_12h-JUND_MA0492.2 11 bp overlap

Motif DE_24h DE_24h-JUND_MA0492.2 11 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 197 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 197 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 118 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 197 bp overlap

NFIB 3 datasets

Motif DE_12h DE_12h-NFIB_MA1643.2 17 bp overlap

Motif DE_24h DE_24h-NFIB_MA1643.2 17 bp overlap

Motif ES_0h ES_0h-NFIB_MA1643.2 17 bp overlap

NFIX 3 datasets

Motif DE_12h DE_12h-NFIX_MA1528.2 14 bp overlap

Motif DE_24h DE_24h-NFIX_MA1528.2 14 bp overlap

Motif ES_0h ES_0h-NFIX_MA1528.2 14 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 197 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 197 bp overlap

Nrf1 1 dataset

Motif DE_12h DE_12h-Nrf1_MA0506.3 12 bp overlap

PCBP1 1 dataset

ChIP K-562 GSE120104.PCBP1.K-562 140 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 164 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 197 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 197 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 197 bp overlap

Plagl1 2 datasets

Motif DE_12h DE_12h-Plagl1_MA1615.2 8 bp overlap

Motif DE_24h DE_24h-Plagl1_MA1615.2 8 bp overlap

RARA 2 datasets

ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 197 bp overlap

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 188 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 157 bp overlap

RBFOX2 1 dataset

ChIP HepG2 ENCFF554DMZ 197 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 197 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 197 bp overlap

RXR 1 dataset

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 197 bp overlap

RYBP 1 dataset

ChIP WA01 GSE104690.RYBP.WA01 186 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 197 bp overlap

SMAD2 1 dataset

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 197 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 197 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 151 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 197 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 177 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 197 bp overlap

SOX2 1 dataset

ChIP RENVM GSE49404.SOX2.RENVM 157 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 197 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 197 bp overlap

STAT1::STAT2 2 datasets

Motif DE_12h DE_12h-STAT1STAT2_MA0517.2 13 bp overlap

Motif DE_24h DE_24h-STAT1STAT2_MA0517.2 13 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 191 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 197 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 191 bp overlap

TAF15 2 datasets

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 178 bp overlap

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 170 bp overlap

TAL1 1 dataset

ChIP ME-1 GSE46044.TAL1.ME-1 173 bp overlap

TBP 1 dataset

ChIP WA01 ENCSR000ECB.TBP.WA01 166 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 121 bp overlap

TFAP2B 1 dataset

Motif DE_12h DE_12h-TFAP2B_MA0813.1 13 bp overlap

TFAP2C 2 datasets

Motif DE_12h DE_12h-TFAP2C_MA0814.3 9 bp overlap

Motif DE_24h DE_24h-TFAP2C_MA0814.3 9 bp overlap

TP53 1 dataset

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 197 bp overlap

TP63 1 dataset

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 141 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 197 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 164 bp overlap

WDR5 1 dataset

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 197 bp overlap

YY1 3 datasets

ChIP H1 ENCFF524BTL 197 bp overlap

ChIP H1 ENCFF524BTL 84 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 187 bp overlap

ZBTB33 1 dataset

ChIP K562 ENCFF427SDV 127 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 197 bp overlap

ZFP14 1 dataset

Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap

ZFP57 1 dataset

ChIP hESC GSE115387.ZFP57.hESC 173 bp overlap

ZFX 1 dataset

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 189 bp overlap

ZIC1 1 dataset

Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap

ZIC4 1 dataset

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

ZIC5 1 dataset

Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap

ZNF445 1 dataset

ChIP HEK293T GSE78099.ZNF445.HEK293T 180 bp overlap

ZNF454 1 dataset

Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 141 bp overlap

ZNF530 3 datasets

Motif DE_12h DE_12h-ZNF530_MA1981.2 14 bp overlap

Motif DE_24h DE_24h-ZNF530_MA1981.2 14 bp overlap

Motif ES_0h ES_0h-ZNF530_MA1981.2 14 bp overlap

ZNF610 1 dataset

Motif DE_12h DE_12h-ZNF610_MA1713.2 10 bp overlap

ZNF786 1 dataset

ChIP HEK293T GSE78099.ZNF786.HEK293T 161 bp overlap

ZNF93 1 dataset

Motif DE_12h DE_12h-ZNF93_MA1721.2 14 bp overlap